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Searching for up to 100 curated homologs for Ac3H11_13 FitnessBrowser__acidovorax_3H11:Ac3H11_13 (261 a.a.)

Found high-coverage hits (≥70%) to 32 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

PHEC_PSEAE / Q01269 Cyclohexadienyl dehydratase; EC 4.2.1.51; EC 4.2.1.91 from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
Q01269 arogenate dehydratase (EC 4.2.1.91) from Pseudomonas aeruginosa (see 3 papers)
    37% identity, 89% coverage of query (164 bits)

5t0wA Crystal structure of the ancestral amino acid-binding protein anccdt- 1, a precursor of cyclohexadienyl dehydratase
    34% identity, 89% coverage of query (130 bits)

Build an alignment

Build an alignment for Ac3H11_13 and 2 homologs with ≥ 30% identity

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Additional hits (identity < 30%)

5kkwA / Q4FLR5 Crystal structure of sar11_1068 bound to a sulfobetaine (3-(1- methylpiperidinium-1-yl)propane-1-sulfonate)
    28% identity, 79% coverage of query (87.0 bits)

3k4uE / Q7MAG0 Crystal structure of putative binding component of abc transporter from wolinella succinogenes dsm 1740 complexed with lysine
    25% identity, 85% coverage of query (82.8 bits)

Ac3H11_2555 ABC transporter for L-Histidine, periplasmic substrate-binding component 1 from Acidovorax sp. GW101-3H11
    27% identity, 85% coverage of query (76.3 bits)

TcyJ / b1920 cystine ABC transporter periplasmic binding protein (EC 7.4.2.12) from Escherichia coli K-12 substr. MG1655 (see 12 papers)
tcyJ / P0AEM9 cystine ABC transporter periplasmic binding protein (EC 7.4.2.12) from Escherichia coli (strain K12) (see 13 papers)
TCYJ_ECOLI / P0AEM9 L-cystine-binding protein TcyJ; CBP; Protein FliY; Sulfate starvation-induced protein 7; SSI7 from Escherichia coli (strain K12) (see 6 papers)
TC 3.A.1.3.10 / P0AEM9 Cystine-binding periplasmic protein FLIY aka CysX aka B1920, component of Cystine/cysteine/diaminopimelate transporter, CysXYZ; these proteins are also designated FliY/YecS/YecC from Escherichia coli (see 7 papers)
    24% identity, 97% coverage of query (72.8 bits)

4zv2A An ancestral arginine-binding protein bound to glutamine
    25% identity, 85% coverage of query (71.6 bits)

4zv1A An ancestral arginine-binding protein bound to arginine (see paper)
    25% identity, 85% coverage of query (70.1 bits)

4h5fA Crystal structure of an amino acid abc transporter substrate-binding protein from streptococcus pneumoniae canada mdr_19a bound to l- arginine, form 1
    29% identity, 83% coverage of query (67.4 bits)

2ylnA / Q5F9M1 Crystal structure of the l-cystine solute receptor of neisseria gonorrhoeae in the closed conformation (see paper)
    25% identity, 90% coverage of query (66.6 bits)

cjaA / CAJ20048.1 glutamine-binding protein from Campylobacter jejuni (see paper)
    29% identity, 77% coverage of query (63.9 bits)

AAC45332.1 high affinity cystine binding protein from Lactobacillus reuteri (see 4 papers)
    23% identity, 81% coverage of query (58.2 bits)

2yjpA / Q5F5B5 Crystal structure of the solute receptors for l-cysteine of neisseria gonorrhoeae (see paper)
    25% identity, 87% coverage of query (57.0 bits)

TCYA_BACSU / P42199 L-cystine-binding protein TcyA from Bacillus subtilis (strain 168) (see paper)
TC 3.A.1.3.14 / P42199 TcyA (YckK), component of Uptake system for L-cystine from Bacillus subtilis (see 5 papers)
    22% identity, 99% coverage of query (57.0 bits)

4ymxA / Q8RCC4 Crystal structure of the substrate binding protein of an amino acid abc transporter (see paper)
    24% identity, 85% coverage of query (55.8 bits)

GlnH / b0811 L-glutamine ABC transporter periplasmic binding protein (EC 7.4.2.1) from Escherichia coli K-12 substr. MG1655 (see 13 papers)
GlnH / P0AEQ3 L-glutamine ABC transporter periplasmic binding protein (EC 7.4.2.1) from Escherichia coli (strain K12) (see 13 papers)
GLNH_ECOLI / P0AEQ3 Glutamine-binding periplasmic protein; GlnBP from Escherichia coli (strain K12) (see paper)
TC 3.A.1.3.2 / P0AEQ3 Glutamine-binding periplasmic protein GlnH aka B0811 aka GlnBP, component of Three component ABC L-glutamine porter. The basal ATPase activity (ATP hydrolysis in the absence of substrate) is mainly caused by the docking of the closed-unliganded state of GlnH onto the transporter domain of GlnPQ. Unlike glutamine, arginine binds both GlnH domains, but does not trigger their closing. Comparison of the ATPase activity in nanodiscs with glutamine transport in proteoliposomes suggested that the stoichiometry of ATP per substrate is close to two from Escherichia coli (see 7 papers)
glnH / GB|AAN79369.1 glutamine ABC transporter, periplasmic glutamine-binding protein GlnH from Escherichia coli (see 7 papers)
    24% identity, 98% coverage of query (55.5 bits)

6svfA / Q9WZ62 Crystal structure of the p235gk mutant of argbp from t. Maritima (see paper)
    22% identity, 88% coverage of query (54.7 bits)

8gtuA / C6XGT2 Crystal structure of putative amino acid binding periplasmic abc transporter protein from candidatus liberibacter asiaticus in complex with clidinium (see paper)
    24% identity, 85% coverage of query (52.8 bits)

C6XGT2 ABC-type cystine transporter (EC 7.4.2.12) from Candidatus Liberibacter asiaticus (see paper)
    24% identity, 85% coverage of query (52.4 bits)

8gu1A Crystal structure of putative amino acid binding periplasmic abc transporter protein from candidatus liberibacter asiaticus in complex with pimozide
    24% identity, 85% coverage of query (52.4 bits)

6aalA Crystal structure of putative amino acid binding periplasmic abc transporter protein from candidatus liberibacter asiaticus in complex with arginine
    24% identity, 85% coverage of query (52.4 bits)

6a80A Crystal structure of putative amino acid binding periplasmic abc transporter protein from candidatus liberibacter asiaticus in complex with cystine
    24% identity, 85% coverage of query (52.4 bits)

ArtI / b0863 putative ABC transporter periplasmic binding protein ArtI from Escherichia coli K-12 substr. MG1655 (see 3 papers)
ARTI_ECOLI / P30859 Putative ABC transporter arginine-binding protein 2 from Escherichia coli (strain K12) (see paper)
TC 3.A.1.3.3 / P30859 ArtI aka B0863, component of Arginine porter from Escherichia coli (see 7 papers)
    23% identity, 95% coverage of query (50.4 bits)

8eyzA / P0AEQ3 Engineered glutamine binding protein bound to gln and a cobaloxime ligand (see paper)
    24% identity, 85% coverage of query (49.7 bits)

HP15_3031 L-arginine ABC transporter, periplasmic substrate-binding component ArtJ/HisJ/ArtI/AotJ/ArgT from Marinobacter adhaerens HP15
    24% identity, 80% coverage of query (48.5 bits)

2q2cA Crystal structures of the arginine-, lysine-, histidine-binding protein artj from the thermophilic bacterium geobacillus stearothermophilus
    22% identity, 85% coverage of query (48.5 bits)

2pvuA Crystal structures of the arginine-, lysine-, histidine-binding protein artj from the thermophilic bacterium geobacillus stearothermophilus
    22% identity, 85% coverage of query (48.5 bits)

2q2aA / D0VWX8 Crystal structures of the arginine-, lysine-, histidine-binding protein artj from the thermophilic bacterium geobacillus stearothermophilus (see paper)
    22% identity, 85% coverage of query (48.1 bits)

ARTJ_CHLPN / Q9Z869 Probable ABC transporter arginine-binding protein ArtJ from Chlamydia pneumoniae (Chlamydophila pneumoniae) (see 2 papers)
    22% identity, 95% coverage of query (47.8 bits)

3qaxB / Q9Z869 Crystal structure analysis of the cpb0502
    22% identity, 84% coverage of query (47.0 bits)

4c0rA / Q93DA5 Molecular and structural basis of glutathione import in gram-positive bacteria via gsht and the cystine abc importer tcybc of streptococcus mutans. (see paper)
    21% identity, 85% coverage of query (44.3 bits)

8ovoA / P37902,P42212 X-ray structure of the sf-iglusnfr-s72a in complex with l-aspartate
    26% identity, 90% coverage of query (44.3 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory