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Searching for up to 100 curated homologs for Ac3H11_1480 Aldehyde dehydrogenase B (EC 1.2.1.22) (486 a.a.)

Found high-coverage hits (≥70%) to 100 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

davD / Q9I6M5 glutarate semialdehyde dehydrogenase (EC 1.2.1.20) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see 2 papers)
DAVD_PSEAE / Q9I6M5 Glutarate-semialdehyde dehydrogenase; EC 1.2.1.- from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
    65% identity, 99% coverage of query (684 bits)

A0A0F4THK8 succinate-semialdehyde dehydrogenase [NAD(P)+] (EC 1.2.1.16) from Pseudomonas fluorescens (see paper)
    65% identity, 99% coverage of query (674 bits)

gabD / Q4KKA2 NAD(P)-dependent succinate-semialdehyde dehydrogenase (EC 1.2.1.16) from Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5) (see paper)
    65% identity, 99% coverage of query (669 bits)

PfGW456L13_495 Glutarate-semialdehyde dehydrogenase (EC 1.2.1.20) from Pseudomonas fluorescens GW456-L13
    64% identity, 99% coverage of query (667 bits)

gabD1 / Q0K2K1 NAD(P)+-dependent succinate semialdehyde dehydrogenase monomer (EC 1.2.1.16) from Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier 337) (see paper)
Q0K2K1 succinate-semialdehyde dehydrogenase [NAD(P)+] (EC 1.2.1.16) from Cupriavidus necator (see paper)
    66% identity, 99% coverage of query (664 bits)

GabD / b2661 succinate-semialdehyde dehydrogenase (NADP+) GabD (EC 1.2.1.79) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
gabD / P25526 succinate-semialdehyde dehydrogenase (NADP+) GabD (EC 1.2.1.79; EC 1.2.1.20) from Escherichia coli (strain K12) (see 22 papers)
GABD_ECOLI / P25526 Succinate-semialdehyde dehydrogenase [NADP(+)] GabD; SSDH; Glutarate-semialdehyde dehydrogenase; EC 1.2.1.79; EC 1.2.1.- from Escherichia coli (strain K12) (see 4 papers)
P25526 succinate-semialdehyde dehydrogenase (NADP+) (EC 1.2.1.79) from Escherichia coli K-12 (see paper)
GB|AAC75708.1 succinate-semialdehyde dehydrogenase [NAD(P)+]; EC 1.2.1.16 from Escherichia coli K12 (see 5 papers)
    64% identity, 99% coverage of query (664 bits)

3jz4A / P25526 Crystal structure of e. Coli NADP dependent enzyme (see paper)
    64% identity, 99% coverage of query (662 bits)

AO353_11505 succinate-semialdehyde dehydrogenase (EC 1.2.1.16) from Pseudomonas fluorescens FW300-N2E3
    64% identity, 99% coverage of query (660 bits)

Q88RC0 glutarate-semialdehyde dehydrogenase (EC 1.2.1.20) from Pseudomonas putida (see 2 papers)
    64% identity, 99% coverage of query (659 bits)

SLAD_PSEPU / P0DOV9 3-sulfolactaldehyde dehydrogenase; SLA dehydrogenase; EC 1.2.1.97 from Pseudomonas putida (Arthrobacter siderocapsulatus) (see paper)
    63% identity, 99% coverage of query (655 bits)

gabD / Q9RBF6 NADP-dependent succinate semialdehyde dehydrogenase (EC 1.2.1.79) from Cupriavidus necator (see paper)
Q9RBF6 succinate-semialdehyde dehydrogenase [NAD(P)+] (EC 1.2.1.16); succinate-semialdehyde dehydrogenase (NADP+) (EC 1.2.1.79) from Cupriavidus necator (see paper)
    65% identity, 99% coverage of query (653 bits)

SO1275 succinate-semialdehyde dehydrogenase (NADP+) [EC: 1.2.1.16] from Shewanella oneidensis MR-1
    65% identity, 99% coverage of query (641 bits)

nmpF / A0A222FYW4 succinate-semialdehyde dehydrogenase (NAD+) (EC 1.2.1.24) from Alicycliphilus sp. (see paper)
    64% identity, 98% coverage of query (632 bits)

TGNE_ACIAD / Q6F9G0 Succinate semialdehyde dehydrogenase; SSA dehydrogenase; EC 1.2.1.24 from Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1) (see paper)
    58% identity, 99% coverage of query (598 bits)

SSDH_ARATH / Q9SAK4 Succinate-semialdehyde dehydrogenase, mitochondrial; At-SSADH1; Aldehyde dehydrogenase family 5 member F1; NAD(+)-dependent succinic semialdehyde dehydrogenase; Protein ENLARGED FIL EXPRESSING DOMAIN 1; EC 1.2.1.24 from Arabidopsis thaliana (Mouse-ear cress) (see 8 papers)
    57% identity, 99% coverage of query (580 bits)

A0A0D5YDF1 succinate-semialdehyde dehydrogenase (NADP+) (EC 1.2.1.79) from Acinetobacter baumannii (see paper)
    60% identity, 93% coverage of query (576 bits)

8c54A Cryo-em structure of nadh bound sla dehydrogenase rlgabd from rhizobium leguminosarum bv. Trifolii srd1565
    58% identity, 99% coverage of query (574 bits)

SSDH_RAT / P51650 Succinate-semialdehyde dehydrogenase, mitochondrial; SSADH; Aldehyde dehydrogenase family 5 member A1; NAD(+)-dependent succinic semialdehyde dehydrogenase; EC 1.2.1.24 from Rattus norvegicus (Rat) (see paper)
P51650 aldehyde dehydrogenase (NAD+) (EC 1.2.1.3) from Rattus norvegicus (see paper)
    53% identity, 98% coverage of query (540 bits)

Q9VBP6 succinate-semialdehyde dehydrogenase (NAD+) (EC 1.2.1.24) from Drosophila melanogaster (see paper)
    53% identity, 98% coverage of query (537 bits)

AN3829 succinate-semialdehyde dehydrogenase (Eurofung) from Emericella nidulans (see 2 papers)
    52% identity, 99% coverage of query (537 bits)

ALDH5A1 / P51649 Succinate-semialdehyde dehydrogenase, mitochondrial (EC 1.2.1.24) from Homo sapiens (see 7 papers)
SSDH_HUMAN / P51649 Succinate-semialdehyde dehydrogenase, mitochondrial; Aldehyde dehydrogenase family 5 member A1; NAD(+)-dependent succinic semialdehyde dehydrogenase; EC 1.2.1.24 from Homo sapiens (Human) (see 7 papers)
P51649 succinate-semialdehyde dehydrogenase (NAD+) (EC 1.2.1.24) from Homo sapiens (see 9 papers)
    53% identity, 99% coverage of query (528 bits)

Q3MSM3 succinate-semialdehyde dehydrogenase (NAD+) (EC 1.2.1.24) from Hylobates lar (see paper)
    53% identity, 99% coverage of query (528 bits)

Q6A2H1 succinate-semialdehyde dehydrogenase (NAD+) (EC 1.2.1.24) from Gorilla gorilla (see paper)
    53% identity, 99% coverage of query (527 bits)

Q3MSM4 succinate-semialdehyde dehydrogenase (NAD+) (EC 1.2.1.24) from Pan paniscus (see paper)
    53% identity, 99% coverage of query (527 bits)

2w8qA / P51649 The crystal structure of human ssadh in complex with ssa. (see paper)
    53% identity, 99% coverage of query (527 bits)

2w8rA The crystal structure of human ssadh in complex with NAD+
    53% identity, 99% coverage of query (527 bits)

Q6A2H0 succinate-semialdehyde dehydrogenase (NAD+) (EC 1.2.1.24) from Pan troglodytes (see paper)
    53% identity, 99% coverage of query (526 bits)

Q6A2H2 succinate-semialdehyde dehydrogenase (NAD+) (EC 1.2.1.24) from Pongo pygmaeus pygmaeus (see paper)
    53% identity, 99% coverage of query (526 bits)

B0JFD4 succinate-semialdehyde dehydrogenase (NAD+) (EC 1.2.1.24) from Lucilia cuprina (see paper)
    50% identity, 98% coverage of query (521 bits)

GABD_BACSU / P94428 Succinate-semialdehyde dehydrogenase [NADP(+)]; SSDH; EC 1.2.1.79 from Bacillus subtilis (strain 168) (see 3 papers)
P94428 succinate-semialdehyde dehydrogenase [NAD(P)+] (EC 1.2.1.16) from Bacillus subtilis (see paper)
    54% identity, 93% coverage of query (506 bits)

SSDH1_SCHPO / Q9US47 Putative succinate-semialdehyde dehydrogenase C1002.12c [NADP(+)]; SSDH; EC 1.2.1.16 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
    49% identity, 99% coverage of query (490 bits)

UGA2 / P38067 NAD(P)-dependent succinate semialdehyde dehydrogenase (EC 1.2.1.16) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see paper)
    50% identity, 99% coverage of query (487 bits)

doeC / E1V7V8 aspartate-semialdehyde dehydrogenase (non-phosphorylating) from Halomonas elongata (strain ATCC 33173 / DSM 2581 / NBRC 15536 / NCIMB 2198 / 1H9) (see paper)
DOEC_HALED / E1V7V8 Aspartate-semialdehyde dehydrogenase (Non-phosphorylating); EC 1.2.1.- from Halomonas elongata (strain ATCC 33173 / DSM 2581 / NBRC 15536 / NCIMB 2198 / 1H9) (see paper)
    51% identity, 99% coverage of query (478 bits)

SSDH2_SCHPO / Q9UTM8 Putative succinate-semialdehyde dehydrogenase C139.05 [NADP(+)]; SSDH; EC 1.2.1.16 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
    43% identity, 97% coverage of query (426 bits)

SSDH_PAENI / Q8GAI8 Succinate-semialdehyde dehydrogenase; SsaDH; EC 1.2.1.16 from Paenarthrobacter nicotinovorans (Arthrobacter nicotinovorans) (see paper)
    50% identity, 85% coverage of query (395 bits)

chnE / Q9R2F4 6-oxohexanoate dehydrogenase (EC 1.2.1.63) from Acinetobacter johnsonii (see 2 papers)
    40% identity, 96% coverage of query (368 bits)

5x5tA / Q1JUP4 Crystal structure of alpha-ketoglutarate semialdehyde dehydrogenase (kgsadh) from azospirillum brasilense (see paper)
    43% identity, 97% coverage of query (365 bits)

KGSD1_AZOBR / Q1JUP4 Alpha-ketoglutaric semialdehyde dehydrogenase 1; alphaKGSA dehydrogenase 1; 2,5-dioxovalerate dehydrogenase 1; 2-oxoglutarate semialdehyde dehydrogenase 1; KGSADH-I; Succinate-semialdehyde dehydrogenase [NAD(+)]; SSDH; EC 1.2.1.26; EC 1.2.1.24 from Azospirillum brasilense (see paper)
Q1JUP4 succinate-semialdehyde dehydrogenase (NAD+) (EC 1.2.1.24); 2,5-dioxovalerate dehydrogenase (EC 1.2.1.26) from Azospirillum brasilense (see 4 papers)
    42% identity, 100% coverage of query (365 bits)

5x5uA Crystal structure of alpha-ketoglutarate-semialdehyde dehydrogenase (kgsadh) complexed with NAD
    43% identity, 97% coverage of query (365 bits)

ALD5 / P40047 aldehyde dehydrogenase, mitochondrial (EC 1.2.1.4; EC 1.2.1.3) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see paper)
ALDH5_YEAST / P40047 Aldehyde dehydrogenase 5, mitochondrial; EC 1.2.1.-; EC 1.2.1.4 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 6 papers)
    41% identity, 95% coverage of query (349 bits)

4pxlA / Q8S532 Structure of zm aldh2-3 (rf2c) in complex with NAD (see paper)
    41% identity, 96% coverage of query (343 bits)

4neaA / A0A0H2X0S3 1.90 angstrom resolution crystal structure of betaine aldehyde dehydrogenase (betb) from staphylococcus aureus in complex with NAD+ and bme-free cys289 (see paper)
    38% identity, 97% coverage of query (343 bits)

aldA / RF|XP_658158.1 aldehyde dehydrogenase ALDH; EC 1.2.1.3 from Emericella nidulans (see 5 papers)
    41% identity, 95% coverage of query (342 bits)

Q9L4P8 betaine-aldehyde dehydrogenase (EC 1.2.1.8) from Staphylococcus aureus (see paper)
    38% identity, 97% coverage of query (342 bits)

AL2C4_ARATH / Q56YU0 Aldehyde dehydrogenase family 2 member C4; ALDH1a; Protein REDUCED EPIDERMAL FLUORESCENCE 1; EC 1.2.1.3 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
    38% identity, 98% coverage of query (342 bits)

cymC / O33455 cumic aldehyde dehydrogenase (EC 1.2.1.29) from Pseudomonas putida (see paper)
cymc / AAB62298.1 p-cumic aldehyde dehydrogenase from Pseudomonas putida (see 3 papers)
    41% identity, 98% coverage of query (341 bits)

AL1A1_RAT / P51647 Aldehyde dehydrogenase 1A1; 3-deoxyglucosone dehydrogenase; ALDH-E1; ALHDII; Aldehyde dehydrogenase family 1 member A1; Aldehyde dehydrogenase, cytosolic; Retinal dehydrogenase 1; RALDH 1; RalDH1; EC 1.2.1.19; EC 1.2.1.28; EC 1.2.1.3; EC 1.2.1.36 from Rattus norvegicus (Rat) (see 3 papers)
P51647 retinal dehydrogenase (EC 1.2.1.36) from Rattus norvegicus (see 5 papers)
    39% identity, 98% coverage of query (340 bits)

ahgD / H2IFE7 3,6-anhydro-L-galactose dehydrogenase (EC 1.2.1.92) from Vibrio sp. (strain EJY3) (see paper)
AHGD_VIBSJ / H2IFE7 3,6-anhydro-alpha-L-galactose dehydrogenase; AHG dehydrogenase; EC 1.2.1.92 from Vibrio sp. (strain EJY3) (see paper)
H2IFE7 3,6-anhydro-alpha-L-galactose dehydrogenase (EC 1.2.1.92) from Vibrio sp. (see paper)
    38% identity, 97% coverage of query (337 bits)

Q9LRE9 aldehyde dehydrogenase [NAD(P)+] (EC 1.2.1.5) from Oryza sativa (see paper)
    41% identity, 96% coverage of query (336 bits)

AL1A7_MOUSE / O35945 Aldehyde dehydrogenase, cytosolic 1; ALDH class 1; ALDH-E1; ALHDII; Aldehyde dehydrogenase family 1 member A7; Aldehyde dehydrogenase phenobarbital-inducible; EC 1.2.1.3 from Mus musculus (Mouse) (see paper)
O35945 aldehyde dehydrogenase (NAD+) (EC 1.2.1.3) from Mus musculus (see paper)
    38% identity, 98% coverage of query (334 bits)

Q9FAB1 long-chain-aldehyde dehydrogenase (EC 1.2.1.48) from Geobacillus thermoleovorans (see paper)
    42% identity, 96% coverage of query (334 bits)

6j76A Structure of 3,6-anhydro-l-galactose dehydrogenase in complex with nap (see paper)
    37% identity, 96% coverage of query (334 bits)

AL1A1_MOUSE / P24549 Aldehyde dehydrogenase 1A1; 3-deoxyglucosone dehydrogenase; ALDH-E1; ALHDII; Aldehyde dehydrogenase family 1 member A1; Aldehyde dehydrogenase, cytosolic; Retinal dehydrogenase 1; RALDH 1; RalDH1; EC 1.2.1.19; EC 1.2.1.28; EC 1.2.1.3; EC 1.2.1.36 from Mus musculus (Mouse) (see 4 papers)
P24549 retinal dehydrogenase (EC 1.2.1.36) from Mus musculus (see 3 papers)
    38% identity, 98% coverage of query (333 bits)

Q9FRX7 aldehyde dehydrogenase [NAD(P)+] (EC 1.2.1.5) from Oryza sativa (see paper)
    39% identity, 96% coverage of query (333 bits)

AL1L1_MOUSE / Q8R0Y6 Cytosolic 10-formyltetrahydrofolate dehydrogenase; 10-FTHFDH; FDH; Aldehyde dehydrogenase family 1 member L1; EC 1.5.1.6 from Mus musculus (Mouse) (see paper)
    39% identity, 98% coverage of query (332 bits)

4pz2B / W8SZG1 Structure of zm aldh2-6 (rf2f) in complex with NAD (see paper)
    40% identity, 98% coverage of query (332 bits)

ALDH4_BACSU / O34660 Putative aldehyde dehydrogenase DhaS; EC 1.2.1.3 from Bacillus subtilis (strain 168) (see paper)
    39% identity, 96% coverage of query (332 bits)

7rluA / P28037 Structure of aldh1l1 (10-formyltetrahydrofolate dehydrogenase) in complex with NADP (see paper)
    38% identity, 99% coverage of query (331 bits)

4go2A Crystal structure of thE C-terminal domain of 10'formyltetrahydrofolate dehydrogenase in complex with thio-NADP
    38% identity, 99% coverage of query (331 bits)

2o2rA Crystal structure of thE C-terminal domain of rat 10'formyltetrahydrofolate dehydrogenase in complex with NADPH
    38% identity, 99% coverage of query (331 bits)

praB / C4TP02 2-hydroxymuconate-6-semialdehyde dehydrogenase (EC 1.2.1.85) from Paenibacillus sp. JJ-1b (see paper)
praB / BAH79100.1 2-hydroxymuconate-6-semialdehyde dehydrogenase from Paenibacillus sp. JJ-1b (see paper)
    38% identity, 96% coverage of query (330 bits)

AL1L1_RAT / P28037 Cytosolic 10-formyltetrahydrofolate dehydrogenase; 10-FTHFDH; FDH; Aldehyde dehydrogenase family 1 member L1; FBP-CI; EC 1.5.1.6 from Rattus norvegicus (Rat) (see 7 papers)
P28037 formyltetrahydrofolate dehydrogenase (EC 1.5.1.6) from Rattus norvegicus (see 3 papers)
    38% identity, 99% coverage of query (329 bits)

AL1A7_RAT / P13601 Aldehyde dehydrogenase, cytosolic 1; ALDH class 1; ALDH-E1; ALHDII; Aldehyde dehydrogenase family 1 member A7; Aldehyde dehydrogenase phenobarbital-inducible; EC 1.2.1.3 from Rattus norvegicus (Rat) (see paper)
    38% identity, 98% coverage of query (328 bits)

O14293 Putative aldehyde dehydrogenase-like protein C9E9.09c; EC 1.2.1.- from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
    38% identity, 95% coverage of query (328 bits)

BADH1_ORYSJ / O24174 Betaine aldehyde dehydrogenase 1; OsBADH1; EC 1.2.1.8 from Oryza sativa subsp. japonica (Rice) (see 3 papers)
O24174 betaine-aldehyde dehydrogenase (EC 1.2.1.8) from Oryza sativa Japonica Group (see paper)
    39% identity, 97% coverage of query (324 bits)

7radA Crystal structure analysis of aldh1b1
    37% identity, 98% coverage of query (323 bits)

7mjdA Crystal structure analysis of aldh1b1
    37% identity, 98% coverage of query (323 bits)

7mjcA / P30837 Crystal structure analysis of aldh1b1
    37% identity, 98% coverage of query (323 bits)

7yjjC Human cytosolic 10-formyltetrahydrofolate dehydrogenase and gossypol complex
    39% identity, 96% coverage of query (321 bits)

ALDH1A2 / O94788 retinal dehydrogenase 2 (EC 1.2.1.36) from Homo sapiens (see 4 papers)
AL1A2_HUMAN / O94788 Retinal dehydrogenase 2; RALDH 2; RalDH2; Aldehyde dehydrogenase family 1 member A2; ALDH1A2; Retinaldehyde-specific dehydrogenase type 2; RALDH(II); EC 1.2.1.36 from Homo sapiens (Human) (see 3 papers)
O94788 retinal dehydrogenase (EC 1.2.1.36) from Homo sapiens (see 6 papers)
    37% identity, 99% coverage of query (321 bits)

2opxA Crystal structure of lactaldehyde dehydrogenase from escherichia coli
    38% identity, 96% coverage of query (321 bits)

7qk9A Crystal structure of the aldh1a3-atp complex
    37% identity, 96% coverage of query (320 bits)

AL1A2_RAT / Q63639 Retinal dehydrogenase 2; RALDH 2; RalDH2; Aldehyde dehydrogenase family 1 member A2; ALDH1A2; Retinaldehyde-specific dehydrogenase type 2; RALDH(II); EC 1.2.1.36 from Rattus norvegicus (Rat) (see paper)
Q63639 retinal dehydrogenase (EC 1.2.1.36) from Rattus norvegicus (see 4 papers)
    38% identity, 96% coverage of query (320 bits)

7a6qB Crystal structure of human aldehyde dehydrogenase 1a3 in complex with selective nr6 inhibitor compound
    37% identity, 96% coverage of query (320 bits)

7a6qA / P47895 Crystal structure of human aldehyde dehydrogenase 1a3 in complex with selective nr6 inhibitor compound (see paper)
    37% identity, 96% coverage of query (320 bits)

5fhzA Human aldehyde dehydrogenase 1a3 complexed with NAD(+) and retinoic acid
    37% identity, 96% coverage of query (320 bits)

ALDH1L1 / O75891 10-formyltetrahydrofolate dehydrogenase 1 (EC 3.5.1.10; EC 1.5.1.6) from Homo sapiens (see 7 papers)
AL1L1_HUMAN / O75891 Cytosolic 10-formyltetrahydrofolate dehydrogenase; 10-FTHFDH; FDH; Aldehyde dehydrogenase family 1 member L1; EC 1.5.1.6 from Homo sapiens (Human) (see 3 papers)
O75891 formyltetrahydrofolate dehydrogenase (EC 1.5.1.6) from Homo sapiens (see paper)
    39% identity, 96% coverage of query (320 bits)

ALDH1A3 / P47895 retinal dehydrogenase 3 (EC 1.2.1.36) from Homo sapiens (see 3 papers)
AL1A3_HUMAN / P47895 Retinaldehyde dehydrogenase 3; RALDH-3; RalDH3; Aldehyde dehydrogenase 6; Aldehyde dehydrogenase family 1 member A3; ALDH1A3; EC 1.2.1.36 from Homo sapiens (Human) (see 9 papers)
P47895 retinal dehydrogenase (EC 1.2.1.36); aldehyde dehydrogenase [NAD(P)+] (EC 1.2.1.5) from Homo sapiens (see 6 papers)
    37% identity, 96% coverage of query (320 bits)

ALDH1L2 / Q3SY69 10-formyltetrahydrofolate dehydrogenase 2 (EC 3.5.1.10; EC 1.5.1.6) from Homo sapiens (see 4 papers)
AL1L2_HUMAN / Q3SY69 Mitochondrial 10-formyltetrahydrofolate dehydrogenase; Mitochondrial 10-FTHFDH; mtFDH; Aldehyde dehydrogenase family 1 member L2; EC 1.5.1.6 from Homo sapiens (Human) (see 2 papers)
Q3SY69 formyltetrahydrofolate dehydrogenase (EC 1.5.1.6) from Homo sapiens (see paper)
    38% identity, 97% coverage of query (320 bits)

2impA Crystal structure of lactaldehyde dehydrogenase from e. Coli: the ternary complex with lactate (occupancy 0.5) and nadh. Crystals soaked with (l)-lactate.
    38% identity, 96% coverage of query (320 bits)

2iluA / P25553 Crystal structure of lactaldehyde dehydrogenase from e. Coli: the binary complex with NADPH (see paper)
    38% identity, 96% coverage of query (320 bits)

Ald / b1415 aldehyde dehydrogenase A (EC 1.2.1.22; EC 1.2.1.21) from Escherichia coli K-12 substr. MG1655 (see 20 papers)
aldA / P25553 aldehyde dehydrogenase A (EC 1.2.1.22; EC 1.2.1.21) from Escherichia coli (strain K12) (see 19 papers)
ALDA_ECOLI / P25553 Lactaldehyde dehydrogenase; Aldehyde dehydrogenase A; Glycolaldehyde dehydrogenase; EC 1.2.1.22; EC 1.2.1.21 from Escherichia coli (strain K12) (see 8 papers)
P25553 lactaldehyde dehydrogenase (EC 1.2.1.22); D-glyceraldehyde dehydrogenase (NADP+) (EC 1.2.1.89) from Escherichia coli (see 2 papers)
    38% identity, 96% coverage of query (320 bits)

6b5hA Aldh1a2 liganded with NAD and 1-(4-cyanophenyl)-n-(3-fluorophenyl)-3- [4-(methylsulfonyl)phenyl]-1h-pyrazole-4-carboxamide (compound cm121)
    38% identity, 96% coverage of query (319 bits)

6b5gA Aldh1a2 liganded with NAD and (3-ethoxythiophen-2-yl){4-[4-nitro-3- (pyrrolidin-1-yl)phenyl]piperazin-1-yl}methanone (compound 6-118)
    38% identity, 96% coverage of query (319 bits)

6aljA / O94788 Aldh1a2 liganded with NAD and compound win18,446 (see paper)
    38% identity, 96% coverage of query (319 bits)

6tgwA Crystal structure of human aldehyde dehydrogenase 1a3 in complex with a selective inhibitor
    37% identity, 96% coverage of query (317 bits)

BADH_SPIOL / P17202 Aminoaldehyde dehydrogenase BADH; 4-trimethylammoniobutyraldehyde dehydrogenase BADH; Aminobutyraldehyde dehydrogenase BADH; Betaine aldehyde dehydrogenase; SoBADH; EC 1.2.1.-; EC 1.2.1.47; EC 1.2.1.19; EC 1.2.1.8 from Spinacia oleracea (Spinach) (see 5 papers)
P17202 betaine-aldehyde dehydrogenase (EC 1.2.1.8) from Spinacia oleracea (see 3 papers)
    37% identity, 96% coverage of query (317 bits)

3u4jA / Q930S8 Crystal structure of NAD-dependent aldehyde dehydrogenase from sinorhizobium meliloti
    41% identity, 97% coverage of query (317 bits)

6tryA Crystal structure of human aldehyde dehydrogenase 1a3 in complex with mf13 inhibitor compound
    37% identity, 96% coverage of query (316 bits)

4cazA / Q9HTJ1 Crystal structure of betaine aldehyde dehydrogenase from pseudomonas aeruginosa in complex with nadh
    38% identity, 96% coverage of query (316 bits)

2woxA Betaine aldehyde dehydrogenase from pseudomonas aeruginosa with NAD(p) h-catalytic thiol adduct.
    38% identity, 96% coverage of query (316 bits)

2wmeA Crystallographic structure of betaine aldehyde dehydrogenase from pseudomonas aeruginosa
    38% identity, 96% coverage of query (316 bits)

6te5B Crystal structure of human aldehyde dehydrogenase 1a3 in complex with lq43 inhibitor compound
    37% identity, 96% coverage of query (316 bits)

BETB_PSEAE / Q9HTJ1 NAD/NADP-dependent betaine aldehyde dehydrogenase; BADH; EC 1.2.1.8 from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see 3 papers)
Q9HTJ1 betaine-aldehyde dehydrogenase (EC 1.2.1.8) from Pseudomonas aeruginosa (see 5 papers)
    38% identity, 96% coverage of query (315 bits)

AL1A1_HORSE / P15437 Aldehyde dehydrogenase 1A1; 3-deoxyglucosone dehydrogenase; ALDH-E1; ALHDII; Aldehyde dehydrogenase family 1 member A1; Aldehyde dehydrogenase, cytosolic; Retinal dehydrogenase 1; RALDH 1; RalDH1; EC 1.2.1.19; EC 1.2.1.28; EC 1.2.1.3; EC 1.2.1.36 from Equus caballus (Horse) (see paper)
    37% identity, 98% coverage of query (315 bits)

6wsbA / Q3JLL8 Crystal structure of a betaine aldehyde dehydrogenase from burkholderia pseudomallei bound to cofactor NAD (see paper)
    42% identity, 96% coverage of query (315 bits)

AL1A1_SHEEP / P51977 Aldehyde dehydrogenase 1A1; 3-deoxyglucosone dehydrogenase; ALDH-E1; ALHDII; Aldehyde dehydrogenase family 1 member A1; Aldehyde dehydrogenase, cytosolic; Retinal dehydrogenase 1; RALDH 1; RalDH1; EC 1.2.1.19; EC 1.2.1.28; EC 1.2.1.3; EC 1.2.1.36 from Ovis aries (Sheep) (see 2 papers)
    38% identity, 96% coverage of query (315 bits)

5ac0A Ovis aries aldehyde dehydrogenase 1a1 in complex with a duocarmycin analog
    38% identity, 96% coverage of query (314 bits)

5abmA / P51977 Sheep aldehyde dehydrogenase 1a1 (see paper)
    38% identity, 96% coverage of query (314 bits)

1bxsA Sheep liver class 1 aldehyde dehydrogenase with NAD bound
    38% identity, 96% coverage of query (314 bits)

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Build an alignment for Ac3H11_1480 and 100 homologs with ≥ 30% identity

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory