Sites on a Tree

 

Searching for up to 100 curated homologs for Ac3H11_1539 UDP-N-acetylglucosamine 4,6-dehydratase (EC 4.2.1.-) (606 a.a.)

Found high-coverage hits (≥70%) to 9 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

wbiI / GI|3135688 putative epimerase/dehydratase WbiI from Burkholderia pseudomallei (see paper)
    47% identity, 91% coverage of query (461 bits)

wbgZ / Q9F736 UDP-N-acetylglucosamine 4,6-dehydratase (configuration-retaining) (EC 4.2.1.135) from Shigella sonnei (see paper)
    40% identity, 91% coverage of query (383 bits)

EPSC_BACSU / P71052 Probable polysaccharide biosynthesis protein EpsC from Bacillus subtilis (strain 168) (see paper)
    41% identity, 91% coverage of query (362 bits)

RfbU / CAA69127.1 mannosyl-transferase from Vibrio cholerae (see paper)
    40% identity, 91% coverage of query (353 bits)

cpsE polysaccharide capsule synthesis protein CpsE from Streptococcus iniae (see paper)
    38% identity, 86% coverage of query (343 bits)

P72145 UDP-N-acetylglucosamine 4,6-dehydratase (configuration-inverting) (EC 4.2.1.115) from Pseudomonas aeruginosa (see paper)
    40% identity, 92% coverage of query (340 bits)

wbpM / Q9KIC5 UDP-N-acetylglucosamine 4,6-dehydratase (configuration-retaining) (EC 4.2.1.135) from Pseudomonas aeruginosa (see 6 papers)
    40% identity, 92% coverage of query (338 bits)

pglF / Q0P9D4 UDP-N-acetylglucosamine C-6 dehydratase (EC 4.2.1.135) from Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168) (see 3 papers)
PGLF_CAMJE / Q0P9D4 UDP-N-acetyl-alpha-D-glucosamine C6 dehydratase; UDP-GlcNAc C6 dehydratase; Protein glycosylation pathway protein F; UDP-N-acetylglucosamine 4,6-dehydratase (configuration-retaining); EC 4.2.1.135 from Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168) (see paper)
    36% identity, 97% coverage of query (328 bits)

wbkD / Q2YMM0 UDP-N-acetylglucosamine 4,6-dehydratase (configuration-retaining) (EC 4.2.1.135) from Brucella abortus (strain 2308) (see 2 papers)
    37% identity, 86% coverage of query (287 bits)

Build an alignment

Build an alignment for Ac3H11_1539 and 9 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

No additional hits (below 30% identity) were found

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory