Sites on a Tree

 

Searching for up to 100 curated homologs for Ac3H11_2062 FitnessBrowser__acidovorax_3H11:Ac3H11_2062 (416 a.a.)

Found high-coverage hits (≥70%) to 15 curated proteins.

Removed hits that are identical to the query, leaving 14

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

5dviA / H7BRJ8 High resolution crystal structure of glucose complexed periplasmic glucose binding protein (ppgbp) from p. Putida csv86 (see paper)
    57% identity, 95% coverage of query (436 bits)

5dvjA Crystal structure of galactose complexed periplasmic glucose binding protein (ppgbp) from p. Putida csv86
    57% identity, 95% coverage of query (436 bits)

PfGW456L13_1894 ABC transporter for D-Galactose and D-Glucose, periplasmic substrate-binding component from Pseudomonas fluorescens GW456-L13
    54% identity, 97% coverage of query (422 bits)

PS417_22145 glucose/xylose ABC transporter, periplasmic substrate-binding component from Pseudomonas simiae WCS417
    53% identity, 98% coverage of query (406 bits)

8hqqA / Q4FMK2 Crystal structure of the glucose-binding protein sar11_0769 from "candidatus pelagibacter ubique" htcc1062 bound to glucose
    52% identity, 91% coverage of query (399 bits)

TC 3.A.1.1.30 / Q88P38 GtsA (GLcE), component of Glucose porter, GtsABCD from Pseudomonas putida (strain KT2440) (see paper)
    52% identity, 93% coverage of query (389 bits)

4r2bA / A6X5L9 Crystal structure of sugar transporter oant_3817 from ochrobactrum anthropi, target efi-510528, with bound glucose
    48% identity, 94% coverage of query (367 bits)

SMc04259 ABC transporter for D-Cellobiose and D-Salicin, periplasmic substrate-binding protein from Sinorhizobium meliloti 1021
    36% identity, 94% coverage of query (224 bits)

TC 3.A.1.1.24 / Q72KX2 Glucose-binding protein aka TT_C0328, component of The glucose/mannose porter TTC0326-8 plus MalK1 (ABC protein, shared with 3.A.1.1.25) from Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) (see paper)
    32% identity, 93% coverage of query (164 bits)

2b3bA / Q72KX2 Thermus thermophilus glucose/galactose binding protein with bound glucose (see paper)
    32% identity, 87% coverage of query (151 bits)

2b3fA Thermus thermophilus glucose/galactose binding protein bound with galactose
    32% identity, 87% coverage of query (151 bits)

2b3bC Thermus thermophilus glucose/galactose binding protein with bound glucose
    32% identity, 87% coverage of query (151 bits)

Build an alignment

Build an alignment for Ac3H11_2062 and 12 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

GLCS_SACS2 / Q97UZ1 Glucose-binding protein GlcS; GBP from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus) (see 2 papers)
TC 3.A.1.1.13 / Q97UZ1 GlcS, component of Glucose, mannose, galactose porter from Sulfolobus solfataricus (see paper)
    23% identity, 81% coverage of query (75.5 bits)

XACG_HALVD / D4GP35 Xylose/arabinose-binding protein XacG from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii) (see paper)
    22% identity, 88% coverage of query (72.4 bits)

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory