Searching for up to 100 curated homologs for Ac3H11_2202 FitnessBrowser__acidovorax_3H11:Ac3H11_2202 (535 a.a.)
Found high-coverage hits (≥70%) to 18 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
4ga6A / Q5JCX3 Crystal structure of amp phosphorylasE C-terminal deletion mutant in complex with substrates (see paper)
42% identity, 84% coverage of query (322 bits)
deoA / Q5JCX3 AMP phosphorylase (EC 2.4.2.57) from Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (see 2 papers)
AMPPA_THEKO / Q5JCX3 AMP phosphorylase; AMPpase; Nucleoside monophosphate phosphorylase; NMP phosphorylase; EC 2.4.2.57 from Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (Pyrococcus kodakaraensis (strain KOD1)) (see 3 papers)
Q5JCX3 AMP phosphorylase (EC 2.4.2.57) from Thermococcus kodakarensis (see 3 papers)
42% identity, 86% coverage of query (322 bits)
4ga4A Crystal structure of amp phosphorylase n-terminal deletion mutant
44% identity, 76% coverage of query (305 bits)
1brwA / P77836 The crystal structure of pyrimidine nucleoside phosphorylase in a closed conformation (see paper)
30% identity, 71% coverage of query (145 bits)
1brwB The crystal structure of pyrimidine nucleoside phosphorylase in a closed conformation
30% identity, 71% coverage of query (145 bits)
Build an alignment for Ac3H11_2202 and 5 homologs with ≥ 30% identity
Or download the sequences
5olnB / P39142 X-ray structure of the complex pyrimidine-nucleoside phosphorylase from bacillus subtilis at 1.88 a (see paper)
29% identity, 71% coverage of query (135 bits)
PDP_BACSU / P39142 Pyrimidine-nucleoside phosphorylase; PYNP; Py-NPase; EC 2.4.2.2 from Bacillus subtilis (strain 168) (see paper)
pdp / GB|CAB15976.2 pyrimidine-nucleoside phosphorylase; EC 2.4.2.2 from Bacillus subtilis (see paper)
29% identity, 71% coverage of query (134 bits)
A0A0D1XZI7 pyrimidine-nucleoside phosphorylase (EC 2.4.2.2) from Aneurinibacillus migulanus (see paper)
29% identity, 71% coverage of query (134 bits)
Q99N42 thymidine phosphorylase (EC 2.4.2.4) from Mus musculus (see 2 papers)
29% identity, 70% coverage of query (133 bits)
TYMP / P19971 thymidine phosphorylase monomer (EC 2.4.2.3; EC 2.4.2.2) from Homo sapiens (see 13 papers)
TYPH_HUMAN / P19971 Thymidine phosphorylase; TP; Gliostatin; Platelet-derived endothelial cell growth factor; PD-ECGF; TdRPase; EC 2.4.2.4 from Homo sapiens (Human) (see 6 papers)
P19971 thymidine phosphorylase (EC 2.4.2.4) from Homo sapiens (see 30 papers)
29% identity, 73% coverage of query (124 bits)
2j0fA / P19971 Structural basis for non-competitive product inhibition in human thymidine phosphorylase: implication for drug design (see paper)
29% identity, 70% coverage of query (124 bits)
2wk6A Structural features of native human thymidine phosphorylase and in complex with 5-iodouracil
29% identity, 70% coverage of query (124 bits)
1uouA Crystal structure of human thymidine phosphorylase in complex with a small molecule inhibitor
29% identity, 73% coverage of query (123 bits)
P75052 thymidine phosphorylase (EC 2.4.2.4) from Mycoplasma pneumoniae (see paper)
26% identity, 73% coverage of query (122 bits)
5ey3A / Q7CP66 X-ray structure of the thymidine phosphorylase from salmonella typhimurium in complex with cytidine and sulphate
26% identity, 71% coverage of query (107 bits)
Q7CP66 thymidine phosphorylase (EC 2.4.2.4) from Salmonella enterica subsp. enterica serovar Typhimurium (see paper)
26% identity, 71% coverage of query (107 bits)
4yyyB X-ray structure of the thymidine phosphorylase from salmonella typhimurium in complex with uridine
26% identity, 71% coverage of query (107 bits)
4yekA X-ray structure of the thymidine phosphorylase from salmonella typhimurium in complex with thymidine
26% identity, 71% coverage of query (107 bits)
Or start over
Lawrence Berkeley National Laboratory