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Searching for up to 100 curated homologs for Ac3H11_2549 FitnessBrowser__acidovorax_3H11:Ac3H11_2549 (464 a.a.)

Found high-coverage hits (≥70%) to 29 curated proteins.

Removed hits that are identical to the query, leaving 28

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

hutF / Q4KJP1 formiminoglutamate deiminase subunit (EC 3.5.3.13) from Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5) (see paper)
    51% identity, 96% coverage of query (433 bits)

PfGW456L13_330 Formiminoglutamic iminohydrolase (EC 3.5.3.13) from Pseudomonas fluorescens GW456-L13
    51% identity, 96% coverage of query (431 bits)

HUTF_PSEAE / Q9HU77 Formimidoylglutamate deiminase; Formiminoglutamate deiminase; N-formimino-L-glutamate deiminase; N-formimino-L-glutamate iminohydrolase; EC 3.5.3.13 from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see 3 papers)
Q9HU77 formimidoylglutamate deiminase (EC 3.5.3.13); formimidoylglutamase (EC 3.5.3.8) from Pseudomonas aeruginosa (see paper)
    53% identity, 96% coverage of query (429 bits)

4rdvB / Q9HU77 The structure of n-formimino-l-glutamate iminohydrolase from pseudomonas aeruginosa complexed with n-formimino-l-aspartate
    53% identity, 96% coverage of query (429 bits)

3mduA The structure of n-formimino-l-glutamate iminohydrolase from pseudomonas aeruginosa complexed with n-guanidino-l-glutamate
    53% identity, 96% coverage of query (429 bits)

Pf1N1B4_1591 Formiminoglutamic iminohydrolase (EC 3.5.3.13) from Pseudomonas fluorescens FW300-N1B4
    51% identity, 96% coverage of query (427 bits)

Pf6N2E2_3808 Formiminoglutamic iminohydrolase (EC 3.5.3.13) from Pseudomonas fluorescens FW300-N2E2
    51% identity, 96% coverage of query (426 bits)

AO356_09645 Formiminoglutamic iminohydrolase (EC 3.5.3.13) from Pseudomonas fluorescens FW300-N2C3
    51% identity, 96% coverage of query (425 bits)

AO353_12235 Formiminoglutamic iminohydrolase (EC 3.5.3.13) from Pseudomonas fluorescens FW300-N2E3
    51% identity, 96% coverage of query (422 bits)

PS417_01705 Formiminoglutamic iminohydrolase (EC 3.5.3.13) from Pseudomonas simiae WCS417
    50% identity, 96% coverage of query (413 bits)

SMc00673 Formiminoglutamic iminohydrolase (EC 3.5.3.13) from Sinorhizobium meliloti 1021
    49% identity, 96% coverage of query (388 bits)

4f0lB / Q2YIL4 Crystal structure of amidohydrolase from brucella melitensis
    47% identity, 98% coverage of query (388 bits)

PGA1_c36360 Formiminoglutamic iminohydrolase (EC 3.5.3.13) from Phaeobacter inhibens BS107
    48% identity, 94% coverage of query (374 bits)

Build an alignment

Build an alignment for Ac3H11_2549 and 13 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

PA0142 / Q9I6Z0 8-oxoguanine deaminase monomer (EC 3.5.4.32) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
OXODE_PSEAE / Q9I6Z0 8-oxoguanine deaminase; EC 3.5.4.32 from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
Q9I6Z0 8-oxoguanine deaminase (EC 3.5.4.32) from Pseudomonas aeruginosa (see paper)
    27% identity, 87% coverage of query (83.2 bits)

4dzhA / Q8P8H1 Crystal structure of an adenosine deaminase from xanthomonas campestris (target nysgrc-200456) with bound zn
    27% identity, 90% coverage of query (80.1 bits)

4f0rA / Q7NZ90 Crystal structure of an adenosine deaminase homolog from chromobacterium violaceum (target nysgrc-019589) bound zn and 5'- methylthioadenosine (unproductive complex)
    25% identity, 82% coverage of query (72.0 bits)

4f0sA Crystal structure of an adenosine deaminase homolog from chromobacterium violaceum (target nysgrc-019589) with bound inosine.
    25% identity, 82% coverage of query (72.0 bits)

8is4A / A0A4Q9D6T1 Structure of an isocytosine specific deaminase vcz in complexed with 5-fu (see paper)
    25% identity, 77% coverage of query (70.5 bits)

A1RCX5 hydroxydechloroatrazine ethylaminohydrolase (EC 3.5.4.43) from Paenarthrobacter aurescens (see paper)
    26% identity, 76% coverage of query (70.5 bits)

atzB / P95442 hydroxyatrazine ethylaminohydrolase monomer (EC 3.5.4.43) from Pseudomonas sp. (strain ADP) (see 2 papers)
ATZB_PSESD / P95442 Hydroxydechloroatrazine ethylaminohydrolase; Hydroxyatrazine hydrolase; EC 3.5.4.43 from Pseudomonas sp. (strain ADP) (see paper)
    26% identity, 76% coverage of query (70.5 bits)

3lnpA / D3KFX9 Crystal structure of amidohydrolase family protein olei01672_1_465 from oleispira antarctica (see paper)
    24% identity, 84% coverage of query (65.1 bits)

4gbdA Crystal structure of adenosine deaminase from pseudomonas aeruginosa pao1 with bound zn and methylthio-coformycin
    25% identity, 90% coverage of query (63.2 bits)

4dykA / Q9HZ64 Crystal structure of an adenosine deaminase from pseudomonas aeruginosa pao1 (target nysgrc-200449) with bound zn
    25% identity, 90% coverage of query (62.8 bits)

Q9HZ64 S-methyl-5'-thioadenosine deaminase (EC 3.5.4.31) from Pseudomonas aeruginosa (see paper)
    25% identity, 90% coverage of query (62.8 bits)

atzA / P72156 AtzA (EC 3.8.1.8) from Pseudomonas sp. (strain ADP) (see 3 papers)
ATZA_PSESD / P72156 Atrazine chlorohydrolase; EC 3.8.1.8 from Pseudomonas sp. (strain ADP) (see 5 papers)
P72156 atrazine chlorohydrolase (EC 3.8.1.8) from Pseudomonas sp. ADP (see paper)
4v1xE / P72156 The structure of the hexameric atrazine chlorohydrolase, atza (see paper)
    22% identity, 75% coverage of query (55.5 bits)

Q8GG87 atrazine chlorohydrolase (EC 3.8.1.8) from Arthrobacter sp. (see paper)
    22% identity, 75% coverage of query (55.1 bits)

triA / Q9EYU0 melamine deaminase subunit (EC 3.5.4.45) from Paracidovorax citrulli (see 2 papers)
TRIA_PARCI / Q9EYU0 Melamine deaminase; EC 3.5.4.45 from Paracidovorax citrulli (Acidovorax citrulli) (see 3 papers)
Q9EYU0 melamine deaminase (EC 3.5.4.45) from Acidovorax citrulli (see 2 papers)
    21% identity, 75% coverage of query (51.6 bits)

IXPDE_UNKP / P0CI72 Isoxanthopterin deaminase; EC 3.5.4.11 from Unknown prokaryotic organism (see paper)
P0CI72 pterin deaminase (EC 3.5.4.11) from unidentified prokaryotic organism (see paper)
    24% identity, 83% coverage of query (47.0 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory