Searching for up to 100 curated homologs for Ac3H11_2743 FitnessBrowser__acidovorax_3H11:Ac3H11_2743 (362 a.a.)
Found high-coverage hits (≥70%) to 47 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
ACMSD_RAT / Q8R5M5 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; Picolinate carboxylase; EC 4.1.1.45 from Rattus norvegicus (Rat) (see 2 papers)
Q8R5M5 aminocarboxymuconate-semialdehyde decarboxylase (EC 4.1.1.45) from Rattus norvegicus (see 3 papers)
28% identity, 85% coverage of query (121 bits)
4ofcA / Q8TDX5 2.0 angstroms x-ray crystal structure of human 2-amino-3- carboxymuconate-6-semialdehye decarboxylase (see paper)
28% identity, 95% coverage of query (120 bits)
ACMSD / Q8TDX5 aminocarboxymuconate-semialdehyde decarboxylase (EC 4.1.1.45) from Homo sapiens (see 2 papers)
ACMSD_HUMAN / Q8TDX5 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; Picolinate carboxylase; EC 4.1.1.45 from Homo sapiens (Human) (see 2 papers)
Q8TDX5 aminocarboxymuconate-semialdehyde decarboxylase (EC 4.1.1.45) from Homo sapiens (see 5 papers)
28% identity, 95% coverage of query (120 bits)
4ih3A 2.5 angstroms x-ray crystal structure of of human 2-amino-3- carboxymuconate-6-semialdehyde decarboxylase in complex with dipicolinic acid
28% identity, 95% coverage of query (120 bits)
2wm1A The crystal structure of human alpha-amino-beta-carboxymuconate- epsilon-semialdehyde decarboxylase in complex with 1,3- dihydroxyacetonephosphate suggests a regulatory link between NAD synthesis and glycolysis
28% identity, 95% coverage of query (120 bits)
ACMSD_MOUSE / Q8R519 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; Picolinate carboxylase; EC 4.1.1.45 from Mus musculus (Mouse) (see paper)
Q8R519 aminocarboxymuconate-semialdehyde decarboxylase (EC 4.1.1.45) from Mus musculus (see paper)
28% identity, 85% coverage of query (119 bits)
7pwyA Structure of human dimeric acmsd in complex with the inhibitor tes- 1025
30% identity, 76% coverage of query (119 bits)
nbaD / A4IT47 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase (EC 4.1.1.45) from Geobacillus thermodenitrificans (strain NG80-2) (see paper)
30% identity, 78% coverage of query (117 bits)
7pwyC / Q8TDX5 Structure of human dimeric acmsd in complex with the inhibitor tes- 1025 (see paper)
29% identity, 76% coverage of query (115 bits)
6m53B / N1S495 Crystal structure of 2, 3-dihydroxybenzoic acid decarboxylase from fusarium oxysporum (see paper)
28% identity, 75% coverage of query (104 bits)
X0JT48 o-pyrocatechuate decarboxylase (EC 4.1.1.46) from Fusarium odoratissimum NRRL 54006 (see paper)
28% identity, 75% coverage of query (103 bits)
7bpcA Crystal structure of 2, 3-dihydroxybenzoic acid decarboxylase from fusarium oxysporum in complex with 2,5-dhba
28% identity, 75% coverage of query (103 bits)
7bp1A Crystal structure of 2, 3-dihydroxybenzoic acid decarboxylase from fusarium oxysporum in complex with catechol
28% identity, 75% coverage of query (103 bits)
picC / A0A1X9WE52 3,6-dihydroxypicolinate decarboxylase from Alcaligenes faecalis (see paper)
28% identity, 82% coverage of query (94.0 bits)
praH / C4TP08 5-carboxy-2-hydroxymuconate-6-semialdehyde decarboxylase from Paenibacillus sp. JJ-1b (see 3 papers)
praH / BAH79106.1 5-carboxy-2-hydroxymuconate-6-semialdehyde decarboxylase from Paenibacillus sp. JJ-1b (see paper)
25% identity, 72% coverage of query (92.4 bits)
tsdA / Q0SFL6 γ-resorcylate decarboxylase (EC 4.1.1.103) from Rhodococcus jostii (strain RHA1) (see 2 papers)
GRDC_RHOJR / Q0SFL6 Gamma-resorcylate decarboxylase; GRA decarboxylase; 2,6-dihydroxybenzoate decarboxylase; EC 4.1.1.103 from Rhodococcus jostii (strain RHA1) (see paper)
27% identity, 78% coverage of query (92.0 bits)
nbaD / Q83V25 2-amino-3-carboxymuconate 6-semialdehyde decarboxylase (EC 4.1.1.45) from Pseudomonas fluorescens (see paper)
Q83V25 aminocarboxymuconate-semialdehyde decarboxylase (EC 4.1.1.45) from Pseudomonas fluorescens (see 2 papers)
nbaD / BAC65312.1 2-amino-3-carboxymuconate 6-semialdehyde decarboxylase from Pseudomonas fluorescens (see paper)
26% identity, 85% coverage of query (91.7 bits)
7k13C Acmsd in complex with diflunisal derivative 14
26% identity, 85% coverage of query (91.7 bits)
7k12A Acmsd in complex with diflunisal
26% identity, 85% coverage of query (91.7 bits)
2hbvA Crystal structure of alpha-amino-beta-carboxymuconate-epsilon- semialdehyde-decarboxylase (acmsd)
26% identity, 85% coverage of query (91.7 bits)
4qroA / Q12BV1 Crystal structure of dihydroxybenzoic acid decarbboxylase bpro_2061 (target efi-500288) from polaromonas sp. Js666 with bound manganese and an inhibitor, 2-nitroresorcinol
26% identity, 76% coverage of query (89.7 bits)
4eraA / Q83V25 Evidence for a dual role of an active site histidine in alpha-amino- beta-carboxymuconate-epsilon-semialdehyde decarboxylase (see paper)
25% identity, 85% coverage of query (89.4 bits)
GRDC_POLSJ / Q12BV1 Gamma-resorcylate decarboxylase; Gamma-RSD; 2,6-dihydroxybenzoate decarboxylase; 2,6-DHBD; EC 4.1.1.103 from Polaromonas sp. (strain JS666 / ATCC BAA-500) (see paper)
Q12BV1 gamma-resorcylate decarboxylase (EC 4.1.1.103) from Polaromonas sp. JS666 (see paper)
26% identity, 75% coverage of query (89.4 bits)
4ergA Evidence for a dual role of an active site histidine in alpha-amino- beta-carboxymuconate-epsilon-semialdehyde decarboxylase
25% identity, 85% coverage of query (89.4 bits)
graF / Q60GU1 γ-resorcylate decarboxylase monomer (EC 4.1.1.103) from Rhizobium sp. (strain MTP-10005) (see 2 papers)
GRDC_RHIS5 / Q60GU1 Gamma-resorcylate decarboxylase; GRDC; Gamma-RDC; 2,6-dihydroxybenzoate decarboxylase; EC 4.1.1.103 from Rhizobium sp. (strain MTP-10005) (see 3 papers)
Q60GU1 gamma-resorcylate decarboxylase (EC 4.1.1.103) from Rhizobium sp. (see 3 papers)
26% identity, 76% coverage of query (89.0 bits)
2dvtA / Q60GU1 Crystal structure of 2,6-dihydroxybenzoate decarboxylase from rhizobium
26% identity, 75% coverage of query (88.6 bits)
2dvxA Crystal structure of 2,6-dihydroxybenzoate decarboxylase complexed with inhibitor 2,3-dihydroxybenzaldehyde
26% identity, 75% coverage of query (88.6 bits)
2dvuA Crystal structure of 2,6-dihydroxybenzoate decarboxylase complexed with 2,6-dihydroxybenzoate
26% identity, 75% coverage of query (88.6 bits)
GRDC_RHIRD / Q60FX6 Gamma-resorcylate decarboxylase; 2,6-dihydroxybenzoate decarboxylase; Reversible gamma-RA decarboxylase; EC 4.1.1.103 from Rhizobium radiobacter (Agrobacterium tumefaciens) (Agrobacterium radiobacter) (see paper)
Q60FX6 gamma-resorcylate decarboxylase (EC 4.1.1.103) from Agrobacterium tumefaciens (see paper)
26% identity, 75% coverage of query (88.2 bits)
7wjrA Crystal structure of dihydroxybenzoate decarboxylase mutant a63s from aspergillus oryzae in complex with catechol
26% identity, 77% coverage of query (86.7 bits)
7a19A / P80402 2,3-dihydroxybenzoate decarboxylase of aspergillus oryzae (see paper)
25% identity, 77% coverage of query (85.5 bits)
ligW2 / Q84IP8 5-carboxyvanillate decarboxylase from Sphingomonas paucimobilis (see 2 papers)
27% identity, 75% coverage of query (79.3 bits)
ligW / Q8RJ47 5-carboxyvanillate decarboxylase from Sphingomonas paucimobilis (see 2 papers)
ligW / BAB85806.1 5-carboxyvanillate decarboxylase from Sphingomonas paucimobilis (see 3 papers)
ligW / BAB86295.1 5-carboxyvanillate decarboxylase from Sphingomonas paucimobilis (see paper)
28% identity, 70% coverage of query (75.9 bits)
4icmA / G2IN12 Crystal structure of 5-carboxyvanillate decarboxylase ligw from sphingomonas paucimobilis
28% identity, 70% coverage of query (75.9 bits)
4ni8A Crystal structure of 5-carboxyvanillate decarboxylase ligw from sphingomonas paucimobilis complexed with mn and 5-methoxyisophtalic acid
28% identity, 70% coverage of query (75.9 bits)
4ng3A Crystal structure of 5-carboxyvanillate decarboxylase from sphingomonas paucimobilis complexed with 4-hydroxy-3-methoxy-5- nitrobenzoic acid
28% identity, 70% coverage of query (75.9 bits)
4l6dA Crystal structure of 5-carboxyvanillate decarboxylase from sphingomonas paucimobilis complexed with vanillic acid
28% identity, 70% coverage of query (75.9 bits)
4hjwC / E9F0X0 Crystal structure of metarhizium anisopliae idcase in apo form (see paper)
24% identity, 85% coverage of query (75.1 bits)
6dxsA / G2IQQ5 Crystal structure of the ligj hydratase e284q mutant substrate complex with (3z)-2-keto-4-carboxy-3-hexenedioate (see paper)
26% identity, 73% coverage of query (72.0 bits)
6dxqA Crystal structure of the ligj hydratase product complex with 4- carboxy-4-hydroxy-2-oxoadipate
26% identity, 73% coverage of query (72.0 bits)
LIGJ_SPHSK / G2IQQ5 2-keto-4-carboxy-3-hexenedioate hydratase; KCH hydratase; EC 4.2.1.- from Sphingobium sp. (strain NBRC 103272 / SYK-6) (see 3 papers)
ligJ / BAA97116.1 4-oxalomesaconate hydratase from Sphingomonas paucimobilis (see 3 papers)
ligJ / BAB88741.1 4-oxalomesaconate hydratase from Sphingomonas paucimobilis (see 5 papers)
26% identity, 73% coverage of query (71.6 bits)
proH / Q9AQI1 subunit of 4-oxalomesaconate hydratase (EC 4.2.1.83) from Pseudomonas straminea (see 3 papers)
proH / BAB21455.1 4-Oxalomesaconate hydratase from Pseudomonas straminea (see 2 papers)
26% identity, 72% coverage of query (68.2 bits)
ORSB_EMENI / Q5AUW9 Decarboxylase orsB; Orsellinic acid/F9775 biosynthesis cluster protein B; EC 4.1.1.- from Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) (see 4 papers)
orsB putative amidohydrolase from Emericella nidulans (see paper)
26% identity, 76% coverage of query (67.0 bits)
PATG_PENEN / A0A075TXZ1 6-methylsalicylic acid decarboxylase; Patulin biosynthesis cluster protein G; EC 4.1.1.52 from Penicillium expansum (Blue mold rot fungus) (see 8 papers)
25% identity, 73% coverage of query (65.1 bits)
3ij6A / Q5FK79 Crystal structure of an uncharacterized metal-dependent hydrolase from lactobacillus acidophilus
22% identity, 78% coverage of query (59.7 bits)
patG / A1CFL4 6-methylsalicylate decarboxylase (EC 4.1.1.52) from Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107) (see 2 papers)
PATG_ASPCL / A1CFL4 6-methylsalicylic acid decarboxylase; Patulin synthesis protein G; EC 4.1.1.52 from Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107) (see 4 papers)
26% identity, 72% coverage of query (57.4 bits)
T1PRE6 6-methylsalicylate decarboxylase (EC 4.1.1.52) from Aspergillus clavatus (see paper)
26% identity, 72% coverage of query (55.5 bits)
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Lawrence Berkeley National Laboratory