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Searching for up to 100 curated homologs for Ac3H11_2944 FitnessBrowser__acidovorax_3H11:Ac3H11_2944 (443 a.a.)

Found high-coverage hits (≥70%) to 100 curated proteins.

Removed hits that are identical to the query, leaving 99

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

4ryaA / B9JRF8 Crystal structure of abc transporter solute binding protein avi_3567 from agrobacterium vitis s4, target efi-510645, with bound d-mannitol
    65% identity, 93% coverage of query (560 bits)

TC 3.A.1.1.5 / O30831 SmoE, component of Hexitol (glucitol; mannitol) porter from Rhodobacter sphaeroides (Rhodopseudomonas sphaeroides)
    60% identity, 98% coverage of query (524 bits)

BPHYT_RS16115 ABC transporter for D-Sorbitol, periplasmic substrate-binding component from Burkholderia phytofirmans PsJN
    57% identity, 99% coverage of query (520 bits)

mtlE / Q4KC57 polyol ABC-type transporter periplasmic substrate-binding protein from Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5) (see paper)
    59% identity, 95% coverage of query (511 bits)

Pf6N2E2_1963 ABC transporter for D-sorbitol, periplasmic substrate-binding component from Pseudomonas fluorescens FW300-N2E2
    58% identity, 94% coverage of query (510 bits)

AO356_00025 ABC transporter for D-Sorbitol, periplasmic substrate-binding component from Pseudomonas fluorescens FW300-N2C3
    57% identity, 94% coverage of query (508 bits)

TC 3.A.1.1.49 / O30491 MtlE, component of The polyol (mannitol, glucitol (sorbitol), arabitol (arabinitol; lyxitol)) uptake porter, MtlEFGK from Pseudomonas fluorescens
    57% identity, 98% coverage of query (501 bits)

PS417_12715 ABC transporter for D-Mannitol and D-Sorbitol, periplasmic substrate-binding protein from Pseudomonas simiae WCS417
    57% identity, 98% coverage of query (500 bits)

MANBP_PSEAE / Q9I1E0 Mannitol-binding protein from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
    58% identity, 93% coverage of query (494 bits)

PGA1_c13210 ABC transporter for D-Sorbitol, periplasmic substrate-binding component from Phaeobacter inhibens BS107
    55% identity, 98% coverage of query (484 bits)

HSERO_RS17000 ABC transporter for D-sorbitol/xylitol, substrate-binding component from Herbaspirillum seropedicae SmR1
    30% identity, 79% coverage of query (119 bits)

Build an alignment

Build an alignment for Ac3H11_2944 and 11 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

5iaiA / B9JM84 Crystal structure of abc transporter solute binding protein arad_9887 from agrobacterium radiobacter k84, target efi-510945 in complex with ribitol
    27% identity, 91% coverage of query (103 bits)

3jzjA / B0B0V1 Crystal structures of the gach receptor of streptomyces glaucescens gla.O in the unliganded form and in complex with acarbose and an acarbose homolog. Comparison with acarbose-loaded maltose binding protein of salmonella typhimurium. (see paper)
    27% identity, 88% coverage of query (87.8 bits)

3k02A Crystal structures of the gach receptor of streptomyces glaucescens gla.O in the unliganded form and in complex with acarbose and an acarbose homolog. Comparison with acarbose-loaded maltose binding protein of salmonella typhimurium.
    27% identity, 88% coverage of query (87.8 bits)

SM_b21221 ABC transporter for D-Glucosamine, periplasmic substrate-binding protein from Sinorhizobium meliloti 1021
    26% identity, 95% coverage of query (85.1 bits)

TC 3.A.1.1.41 / G4FGN8 Extracellular solute-binding protein family 1, component of Trehalose porter. Also binds sucrose (Boucher and Noll, 2011). Induced by glucose and trehalose. Directly regulated by trehalose-responsive regulator TreR from Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
    25% identity, 88% coverage of query (82.8 bits)

6dtqA / G4XU73 Maltose bound t. Maritima male3 (see paper)
    25% identity, 88% coverage of query (82.8 bits)

smoF / A9CEY9 3-(6-sulfo-α-D-quinovosyl)-sn-glycerol binding protein from Agrobacterium fabrum (strain C58 / ATCC 33970) (see paper)
SMOF_AGRFC / A9CEY9 Sulfoquinovosyl glycerol-binding protein SmoF; SQGro-binding protein SmoF; SQ monooxygenase cluster protein F from Agrobacterium fabrum (strain C58 / ATCC 33970) (Agrobacterium tumefaciens (strain C58)) (see 2 papers)
    24% identity, 74% coverage of query (75.1 bits)

TC 3.A.1.1.7 / O51923 MalE aka PF1739, component of Maltose/trehalose porter (see paper)
    24% identity, 92% coverage of query (74.3 bits)

1eu8A / Q7LYW7 Structure of trehalose maltose binding protein from thermococcus litoralis (see paper)
    24% identity, 87% coverage of query (73.6 bits)

MALE_THELN / Q7LYW7 Trehalose/maltose-binding protein MalE; TMBP from Thermococcus litoralis (strain ATCC 51850 / DSM 5473 / JCM 8560 / NS-C) (see 4 papers)
    24% identity, 92% coverage of query (71.6 bits)

Dshi_0547 ABC transporter for Xylitol, periplasmic substrate-binding component from Dinoroseobacter shibae DFL-12
    24% identity, 84% coverage of query (68.9 bits)

YcjN / b1310 putative ABC transporter periplasmic binding protein YcjN from Escherichia coli K-12 substr. MG1655 (see 4 papers)
TC 3.A.1.1.46 / P76042 Putative ABC transporter periplasmic-binding protein YcjN, component of Probable glucoside uptake porter, YcjNOPV from Escherichia coli (strain K12)
    25% identity, 72% coverage of query (63.9 bits)

TC 3.A.1.1.44 / Q7AKP1 Putative maltose-binding protein, component of MalEFG (K unknown), involved in maltose and maltodextrin uptake from Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
    24% identity, 85% coverage of query (61.6 bits)

5ci5A / A8F7X5 Crystal structure of an abc transporter solute binding protein from thermotoga lettingae tmo (tlet_1705, target efi-510544) bound with alpha-d-tagatose
    23% identity, 81% coverage of query (60.1 bits)

6l0zA The crystal structure of salmonella enterica sugar-binding protein male
    25% identity, 87% coverage of query (51.2 bits)

3ehuA / P0AEX9,P34998 Crystal structure of the extracellular domain of human corticotropin releasing factor receptor type 1 (crfr1) in complex with crf (see paper)
    25% identity, 89% coverage of query (50.1 bits)

MalE / b4034 maltose ABC transporter periplasmic binding protein (EC 7.5.2.1) from Escherichia coli K-12 substr. MG1655 (see 50 papers)
MalE / P0AEX9 maltose ABC transporter periplasmic binding protein (EC 7.5.2.1) from Escherichia coli (strain K12) (see 74 papers)
MALE_ECOLI / P0AEX9 Maltose/maltodextrin-binding periplasmic protein; MMBP; Maltodextrin-binding protein; Maltose-binding protein; MBP from Escherichia coli (strain K12) (see 5 papers)
P0AEX9 ABC-type maltose transporter (subunit 1/4) (EC 7.5.2.1) from Escherichia coli (see paper)
P0AEY0 single-stranded DNA cytosine deaminase (EC 3.5.4.38) from Escherichia coli O157:H7 (see paper)
TC 3.A.1.1.1 / P0AEX9 Maltose-binding periplasmic protein MalE aka B4034, component of Maltooligosaccharide porter. The 3-D structure has been reported by Oldham et al. (2007). An altering access mechanism has been suggested for the maltose transporter resulting from rigid-body rotations (Khare et al., 2009). Bordignon et al. (2010) and Schneider et al. (2012) have reviewed the extensive knowledge available on MalEFGK2, its mode of action and its regulatory interactions from Escherichia coli (see 12 papers)
malE / RF|NP_418458 maltose-binding periplasmic protein from Escherichia coli K12 (see 14 papers)
    25% identity, 94% coverage of query (49.3 bits)

8g3yA Mbp-mcl1 in complex with ligand 34
    25% identity, 75% coverage of query (49.3 bits)

6wh0A / A7LM80,C3SHQ8 Crystal structure of hybcl-2-4 with hybax bh3 (see paper)
    24% identity, 90% coverage of query (48.9 bits)

3jyrA Crystal structures of the gach receptor of streptomyces glaucescens gla.O in the unliganded form and in complex with acarbose and an acarbose homolog. Comparison with acarbose-loaded maltose binding protein of salmonella typhimurium.
    25% identity, 87% coverage of query (48.5 bits)

3n96A / P0AEX9,Q13324 Crystal structure of human crfr2 alpha extracellular domain in complex with urocortin 1
    25% identity, 88% coverage of query (48.1 bits)

3c4mA Structure of human parathyroid hormone in complex with the extracellular domain of its g-protein-coupled receptor (pth1r)
    25% identity, 88% coverage of query (48.1 bits)

3l2jA / P0AEX9,Q03431 Dimeric structure of the ligand-free extracellular domain of the human parathyroid hormone receptor (pth1r) (see paper)
    25% identity, 88% coverage of query (47.8 bits)

4my2A / P0AEX9,Q00604 Crystal structure of norrin in fusion with maltose binding protein (see paper)
    25% identity, 88% coverage of query (47.8 bits)

4wmwA The structure of mbp-mcl1 bound to ligand 5 at 1.9a
    25% identity, 75% coverage of query (47.8 bits)

4wmvA Structure of mbp-mcl1 bound to ligand 4 at 2.4a
    25% identity, 75% coverage of query (47.8 bits)

8svyA Mbp-mcl1 in complex with ligand 10
    25% identity, 75% coverage of query (47.8 bits)

BWI76_RS01830 maltose ABC transporter, substrate-binding component MalE from Klebsiella michiganensis M5al
    25% identity, 94% coverage of query (47.4 bits)

3oaiA / P0AEX9,P25189 Crystal structure of the extra-cellular domain of human myelin protein zero (see paper)
    25% identity, 89% coverage of query (47.4 bits)

3n94A / P0AEX9,P41586 Crystal structure of human pituitary adenylate cyclase 1 receptor- short n-terminal extracellular domain (see paper)
    25% identity, 88% coverage of query (47.4 bits)

6ybjA Structure of mbp-mcl-1 in complex with compound 3e
    25% identity, 75% coverage of query (47.4 bits)

5lofA Crystal structure of the mbp-mcl1 complex with highly selective and potent inhibitor of mcl1
    25% identity, 75% coverage of query (47.4 bits)

6qynA Structure of mbp-mcl-1 in complex with compound 10d
    25% identity, 75% coverage of query (47.4 bits)

6qyoA Structure of mbp-mcl-1 in complex with compound 18a
    25% identity, 75% coverage of query (47.4 bits)

6pfoA / P30988 Crystal structure of n-glycosylated human calcitonin receptor extracellular domain in complex with salmon calcitonin (16-32) (see paper)
    25% identity, 88% coverage of query (47.0 bits)

1r6zZ / P0AEX9,Q9VUQ5 The crystal structure of the argonaute2 paz domain (as a mbp fusion) (see paper)
    25% identity, 88% coverage of query (47.0 bits)

6zhoA / O60894,P0AEX9,Q16602 Crystal structure of a cgrp receptor ectodomain heterodimer with bound high affinity inhibitor (see paper)
    25% identity, 89% coverage of query (47.0 bits)

4b3nA / P0AEX9,Q0PF16 Crystal structure of rhesus trim5alpha pry/spry domain (see paper)
    24% identity, 90% coverage of query (47.0 bits)

4rwgA Crystal structure of the clr:ramp1 extracellular domain heterodimer with bound high affinity cgrp analog
    25% identity, 89% coverage of query (47.0 bits)

7p0iA Crystal structure of a cgrp receptor ectodomain heterodimer bound to macrocyclic inhibitor compound 13
    25% identity, 89% coverage of query (47.0 bits)

8ax6A Crystal structure of a cgrp receptor ectodomain heterodimer bound to macrocyclic inhibitor htl0029882
    25% identity, 89% coverage of query (47.0 bits)

7p0fA Crystal structure of a cgrp receptor ectodomain heterodimer bound to macrocyclic inhibitor htl0028125
    25% identity, 89% coverage of query (47.0 bits)

8ax5A Crystal structure of a cgrp receptor ectodomain heterodimer bound to macrocyclic inhibitor htl0029881
    25% identity, 89% coverage of query (47.0 bits)

4rwfA / O60895,P0AEX9,Q16602 Crystal structure of the clr:ramp2 extracellular domain heterodimer with bound adrenomedullin (see paper)
    25% identity, 88% coverage of query (46.6 bits)

4nufA / P0AEX9,Q62227 Crystal structure of shp/eid1 (see paper)
    25% identity, 87% coverage of query (46.6 bits)

8ax7A Crystal structure of a cgrp receptor ectodomain heterodimer bound to macrocyclic inhibitor htl0031448
    25% identity, 89% coverage of query (46.6 bits)

6qykA Structure of mbp-mcl-1 in complex with compound 7a
    25% identity, 75% coverage of query (46.6 bits)

5w1cA Crystal structure of mbp fused activation-induced cytidine deaminase (aid) in complex with cytidine
    25% identity, 88% coverage of query (46.6 bits)

6qxjA Structure of mbp-mcl-1 in complex with compound 6a
    25% identity, 75% coverage of query (46.6 bits)

4xaiA / P0AEY0,Q9NCL0 Crystal structure of red flour beetle nr2e1/tlx (see paper)
    25% identity, 77% coverage of query (46.2 bits)

7uajB / P03126,P0AEX9 Crystal structure of apo hpv16 e6
    25% identity, 76% coverage of query (46.2 bits)

4xajB / P0AEX9,Q9Y466 Crystal structure of human nr2e1/tlx (see paper)
    25% identity, 77% coverage of query (46.2 bits)

6yblA Structure of mbp-mcl-1 in complex with compound 9m
    25% identity, 75% coverage of query (46.2 bits)

6qylA Structure of mbp-mcl-1 in complex with compound 8a
    25% identity, 75% coverage of query (46.2 bits)

6qgdA Structure of human mcl-1 in complex with thienopyrimidine inhibitor
    25% identity, 75% coverage of query (46.2 bits)

4wgiA A single diastereomer of a macrolactam core binds specifically to myeloid cell leukemia 1 (mcl1)
    25% identity, 75% coverage of query (46.2 bits)

8h68A / P0AEX9,Q8MNT9 Crystal structure of caenorhabditis elegans nmad-1 in complex with nog and mg(ii) (see paper)
    25% identity, 75% coverage of query (46.2 bits)

4wthB Ataxin-3 carboxy terminal region - crystal c2 (triclinic)
    25% identity, 89% coverage of query (46.2 bits)

5jonA / O88703,P0AEY0 Crystal structure of the unliganded form of hcn2 cnbd (see paper)
    25% identity, 75% coverage of query (46.2 bits)

4xajC Crystal structure of human nr2e1/tlx
    25% identity, 77% coverage of query (46.2 bits)

3a3cA / P0AEX9,P36046 Crystal structure of tim40/mia40 fusing mbp, c296s and c298s mutant (see paper)
    24% identity, 87% coverage of query (45.8 bits)

4rwgB Crystal structure of the clr:ramp1 extracellular domain heterodimer with bound high affinity cgrp analog
    25% identity, 87% coverage of query (45.8 bits)

6anvA / L7P7M1,P0AEX9 Crystal structure of anti-crispr protein acrf1 (see paper)
    25% identity, 87% coverage of query (45.8 bits)

4pqkB / B1B3N6,P0AEX9 C-terminal domain of DNA binding protein (see paper)
    25% identity, 76% coverage of query (45.8 bits)

4wviA / P0AEX9,Q5HHB9 Crystal structure of the type-i signal peptidase from staphylococcus aureus (spsb) in complex with a substrate peptide (pep2). (see paper)
    25% identity, 87% coverage of query (45.8 bits)

2vgqA / P0AEX9,Q7Z434 Crystal structure of human ips-1 card (see paper)
    24% identity, 90% coverage of query (45.8 bits)

5ttdA / D2KPJ6,P0AEX9 Minor pilin fctb from s. Pyogenes with engineered intramolecular isopeptide bond (see paper)
    25% identity, 75% coverage of query (45.4 bits)

6x91B Crystal structure of mbp-fused human apobec1
    24% identity, 88% coverage of query (45.4 bits)

6x91A / P0AEX9,P41238 Crystal structure of mbp-fused human apobec1 (see paper)
    24% identity, 88% coverage of query (45.4 bits)

4wmxA The structure of mbp-mcl1 bound to ligand 6 at 2.0a
    25% identity, 75% coverage of query (45.4 bits)

7omtA / P0AEX9 Crystal structure of promacrobody 21 with bound maltose (see paper)
    25% identity, 87% coverage of query (45.1 bits)

2v93A Equillibrium mixture of open and partially-closed species in the apo state of maltodextrin-binding protein by paramagnetic relaxation enhancement nmr
    24% identity, 87% coverage of query (44.7 bits)

8el0A Structure of mbp-mcl-1 in complex with a macrocyclic compound
    25% identity, 75% coverage of query (44.7 bits)

3csbA / P0AEX9 Crystal structure of monobody ysx1/maltose binding protein fusion complex (see paper)
    25% identity, 87% coverage of query (44.7 bits)

3rumA New strategy to analyze structures of glycopeptide antibiotic-target complexes
    24% identity, 87% coverage of query (44.7 bits)

8el1A Structure of mbp-mcl-1 in complex with abbv-467
    25% identity, 75% coverage of query (44.7 bits)

1llsA Crystal structure of unliganded maltose binding protein with xenon
    25% identity, 87% coverage of query (44.7 bits)

1ez9B Structure of maltotetraitol bound to open-form maltodextrin binding protein in p1 crystal form
    25% identity, 87% coverage of query (44.7 bits)

8qsoA Crystal structure of human mcl-1 in complex with compound 1
    25% identity, 75% coverage of query (44.7 bits)

8g3xA Mbp-mcl1 in complex with ligand 32
    25% identity, 75% coverage of query (44.7 bits)

8g3wA Mbp-mcl1 in complex with ligand 28
    25% identity, 75% coverage of query (44.7 bits)

8g3uA Mbp-mcl1 in complex with ligand 21
    25% identity, 75% coverage of query (44.7 bits)

8g3tA Mbp-mcl1 in complex with ligand 12
    25% identity, 75% coverage of query (44.7 bits)

8g3sA / Q07820 Mbp-mcl1 in complex with ligand 11 (see paper)
    25% identity, 75% coverage of query (44.7 bits)

1ytvA Maltose-binding protein fusion to a c-terminal fragment of the v1a vasopressin receptor
    25% identity, 87% coverage of query (44.3 bits)

5z0rB / P0AEX9,Q32ZE1 Structural insight into the zika virus capsid encapsulating the viral genome (see paper)
    25% identity, 87% coverage of query (44.3 bits)

6k7fA / P0AEX9,P53220 Crystal structure of mbpholo-tim21 fusion protein with a 17-residue helical linker (see paper)
    25% identity, 74% coverage of query (43.9 bits)

6ybkA Structure of mbp-mcl-1 in complex with compound 4d
    25% identity, 75% coverage of query (43.9 bits)

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory