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Searching for up to 100 curated homologs for Ac3H11_2950 N-acetyl-gamma-glutamyl-phosphate reductase (EC 1.2.1.38) (312 a.a.)

Found high-coverage hits (≥70%) to 19 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

SMc01801 N-acetylglutamylphosphate reductase (EC 1.2.1.38) from Sinorhizobium meliloti 1021
    53% identity, 97% coverage of query (328 bits)

argC / CAC29374.1 acetylglutamylphosphate reductase from Rhizobium etli (see paper)
    50% identity, 97% coverage of query (297 bits)

Ga0059261_0351 N-acetylglutamylphosphate reductase (EC 1.2.1.38) from Sphingomonas koreensis DSMZ 15582
    49% identity, 97% coverage of query (251 bits)

Build an alignment

Build an alignment for Ac3H11_2950 and 3 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

ARGC_ARATH / Q93Z70 Probable N-acetyl-gamma-glutamyl-phosphate reductase, chloroplastic; AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase; EC 1.2.1.38 from Arabidopsis thaliana (Mouse-ear cress)
    29% identity, 97% coverage of query (101 bits)

ARGC_ORYSJ / Q6AV34 Probable N-acetyl-gamma-glutamyl-phosphate reductase, chloroplastic; AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase; EC 1.2.1.38 from Oryza sativa subsp. japonica (Rice) (see paper)
    30% identity, 89% coverage of query (101 bits)

ARG5,6 arginine biosynthetic enzyme activities from Candida albicans (see 3 papers)
    27% identity, 84% coverage of query (99.0 bits)

ARG56_SCHPO / P31318 Protein arg11, mitochondrial; EC 1.2.1.38; EC 2.7.2.8 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
arg11 / GI|1204210 N-acetyl-gamma-glutamyl-phosphate reductase/acetylglutamate kinase; EC 1.2.1.38; EC 2.7.2.8 from Schizosaccharomyces pombe (see 2 papers)
    30% identity, 85% coverage of query (97.1 bits)

Echvi_3847 N-succinylglutamylphosphate reductase (EC 1.2.1.-) from Echinicola vietnamensis KMM 6221, DSM 17526
    28% identity, 98% coverage of query (97.1 bits)

CA265_RS18540 N-succinylglutamylphosphate reductase (EC 1.2.1.38) from Pedobacter sp. GW460-11-11-14-LB5
    28% identity, 90% coverage of query (95.9 bits)

argC / CAB95020.1 n-acetylglutamate 5-semialdehyde dehydrogenase from Moritella abyssi (see paper)
    29% identity, 83% coverage of query (94.0 bits)

ARGC_GEOSE / Q07906 N-acetyl-gamma-glutamyl-phosphate reductase; AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase; EC 1.2.1.38 from Geobacillus stearothermophilus (Bacillus stearothermophilus) (see paper)
    31% identity, 84% coverage of query (92.8 bits)

BT3759 N-succinylglutamylphosphate reductase (EC 1.2.1.-) from Bacteroides thetaiotaomicron VPI-5482
    25% identity, 98% coverage of query (92.8 bits)

ARG56_YEAST / Q01217 Protein ARG5,6, mitochondrial; EC 1.2.1.38; EC 2.7.2.8 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 3 papers)
Q01217 acetylglutamate kinase (EC 2.7.2.8) from Saccharomyces cerevisiae (see paper)
ARG5,6 / CAA40336.1 acetylglutamate kinase from Saccharomyces cerevisiae (see paper)
    30% identity, 85% coverage of query (81.6 bits)

N515DRAFT_3769 N-acetylglutamylphosphate reductase (EC 1.2.1.38) from Dyella japonica UNC79MFTsu3.2
    28% identity, 82% coverage of query (75.9 bits)

2ozpA Crystal structure of n-acetyl-gamma-glutamyl-phosphate reductase (ttha1904) from thermus thermophilus
    25% identity, 93% coverage of query (72.4 bits)

lysY / O50146 [amino-group carrier protein]-L-2-aminoadipate 6-phosphate reductase (EC 1.2.1.103) from Thermus thermophilus (strain ATCC BAA-163 / DSM 7039 / HB27) (see 2 papers)
LYSY_THET2 / O50146 [LysW]-L-2-aminoadipate 6-phosphate reductase; EC 1.2.1.103 from Thermus thermophilus (strain ATCC BAA-163 / DSM 7039 / HB27) (see 2 papers)
O50146 [amino group carrier protein]-6-phospho-L-2-aminoadipate reductase (EC 1.2.1.103); [amino-group carrier protein]-5-phospho-L-glutamate reductase (EC 1.2.1.106) from Thermus thermophilus (see paper)
    25% identity, 93% coverage of query (70.9 bits)

ArgC / b3958 N-acetylglutamylphosphate reductase (EC 1.2.1.38) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
argC / P11446 N-acetylglutamylphosphate reductase (EC 1.2.1.38) from Escherichia coli (strain K12) (see 4 papers)
ARGC_ECOLI / P11446 N-acetyl-gamma-glutamyl-phosphate reductase; AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase; EC 1.2.1.38 from Escherichia coli (strain K12) (see paper)
P11446 N-acetyl-gamma-glutamyl-phosphate reductase (EC 1.2.1.38) from Escherichia coli (see paper)
    28% identity, 95% coverage of query (70.5 bits)

Q5JFW1 [amino-group carrier protein]-5-phospho-L-glutamate reductase (EC 1.2.1.106) from Thermococcus kodakarensis (see paper)
    24% identity, 82% coverage of query (67.0 bits)

5einA / O50146 Crystal structure of c148a mutant of lysy from thermus thermophilus in complex with NADP+ and lysw-gamma-aminoadipic acid (see paper)
    24% identity, 93% coverage of query (61.2 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory