Searching for up to 100 curated homologs for Ac3H11_3016 FitnessBrowser__acidovorax_3H11:Ac3H11_3016 (675 a.a.)
Found high-coverage hits (≥70%) to 41 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
SM_b21124 3-methylcrotonyl-CoA carboxylase, alpha (biotin-containing) subunit (EC 6.4.1.4) from Sinorhizobium meliloti 1021
53% identity, 99% coverage of query (610 bits)
MCCC1 / Q96RQ3 3-methylcrotonyl-CoA carboxylase α subunit (EC 6.4.1.4) from Homo sapiens (see 4 papers)
MCCA_HUMAN / Q96RQ3 Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial; MCCase subunit alpha; 3-methylcrotonyl-CoA carboxylase 1; 3-methylcrotonyl-CoA carboxylase biotin-containing subunit; 3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha; EC 6.4.1.4 from Homo sapiens (Human) (see 15 papers)
47% identity, 99% coverage of query (604 bits)
Sama_1359 3-methylcrotonyl-CoA carboxylase, alpha (biotin-containing) subunit (EC 6.4.1.4) from Shewanella amazonensis SB2B
50% identity, 100% coverage of query (598 bits)
MCCA_MOUSE / Q99MR8 Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial; MCCase subunit alpha; 3-methylcrotonyl-CoA carboxylase 1; 3-methylcrotonyl-CoA carboxylase biotin-containing subunit; 3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha; EC 6.4.1.4 from Mus musculus (Mouse) (see paper)
48% identity, 99% coverage of query (597 bits)
MCCA_ARATH / Q42523 Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial; MCCase subunit alpha; 3-methylcrotonyl-CoA carboxylase 1; 3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha; EC 6.4.1.4 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
Q42523 methylcrotonoyl-CoA carboxylase (EC 6.4.1.4) from Arabidopsis thaliana (see 2 papers)
46% identity, 99% coverage of query (583 bits)
MCCA_ORYSJ / Q2QMG2 Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial; MCCase subunit alpha; 3-methylcrotonyl-CoA carboxylase 1; 3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha; EC 6.4.1.4 from Oryza sativa subsp. japonica (Rice) (see paper)
47% identity, 99% coverage of query (575 bits)
liuD / Q9I299 methylcrotonyl-CoA carboxylase α-subunit (EC 6.4.1.4) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
Q9I299 methylcrotonoyl-CoA carboxylase (subunit 2/2) (EC 6.4.1.4) from Pseudomonas aeruginosa (see 3 papers)
51% identity, 99% coverage of query (573 bits)
AO356_01595 3-methylcrotonyl-CoA carboxylase, alpha (biotin-containing) subunit (EC 6.4.1.4) from Pseudomonas fluorescens FW300-N2C3
51% identity, 99% coverage of query (567 bits)
Pf1N1B4_3984 3-methylcrotonyl-CoA carboxylase, alpha (biotin-containing) subunit (EC 6.4.1.4) from Pseudomonas fluorescens FW300-N1B4
50% identity, 99% coverage of query (559 bits)
Pf6N2E2_2194 3-methylcrotonyl-CoA carboxylase, alpha (biotin-containing) subunit (EC 6.4.1.4) from Pseudomonas fluorescens FW300-N2E2
50% identity, 99% coverage of query (557 bits)
atuF / Q9HZV6 cis-geranyl-CoA carboxylase α-subunit (EC 6.4.1.5) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
45% identity, 98% coverage of query (528 bits)
mccA 3-methylcrotonyl-CoA carboxylase biotin-containig subunit; EC 6.4.1.4 from Emericella nidulans (see paper)
mccA / AAR23110.1 3-methylcrotonyl-CoA carboxylase biotin-containing subunit from Aspergillus nidulans (see paper)
45% identity, 99% coverage of query (503 bits)
ACCA1_MYCTU / P9WPQ3 Biotin-dependent 3-methylcrotonyl-coenzyme A carboxylase alpha1 subunit; EC 6.3.4.14 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
CAA79609.1 biotin carboxyl carrier protein from Mycobacterium tuberculosis (see paper)
45% identity, 98% coverage of query (498 bits)
Dsui_0516 Propionyl-CoA carboxylase biotin-containing subunit (EC 6.4.1.3) from Dechlorosoma suillum PS
46% identity, 98% coverage of query (498 bits)
pccA / Q3J4D9 propionyl-CoA carboxylase α subunit (EC 6.4.1.3) from Cereibacter sphaeroides (strain ATCC 17023 / DSM 158 / JCM 6121 / CCUG 31486 / LMG 2827 / NBRC 12203 / NCIMB 8253 / ATH 2.4.1.) (see paper)
46% identity, 97% coverage of query (495 bits)
Q9FAF5 biotin carboxylase (EC 6.3.4.14) from Myxococcus xanthus (see paper)
53% identity, 72% coverage of query (484 bits)
PCCA_CAEEL / Q19842 Propionyl-CoA carboxylase alpha chain, mitochondrial; PCCase subunit alpha; Propanoyl-CoA:carbon dioxide ligase subunit alpha; EC 6.4.1.3 from Caenorhabditis elegans (see paper)
Q19842 propionyl-CoA carboxylase (subunit 2/2) (EC 6.4.1.3) from Caenorhabditis elegans (see paper)
42% identity, 99% coverage of query (476 bits)
PCCA_PIG / P0DTA4 Propionyl-CoA carboxylase alpha chain, mitochondrial; PCCase subunit alpha; Propanoyl-CoA:carbon dioxide ligase subunit alpha; EC 6.4.1.3 from Sus scrofa (Pig) (see paper)
43% identity, 99% coverage of query (474 bits)
PCCA_MOUSE / Q91ZA3 Propionyl-CoA carboxylase alpha chain, mitochondrial; PCCase subunit alpha; Propanoyl-CoA:carbon dioxide ligase subunit alpha; EC 6.4.1.3 from Mus musculus (Mouse) (see paper)
43% identity, 99% coverage of query (470 bits)
PCCA_RUEPO / Q5LUF3 Propionyl-CoA carboxylase alpha chain; EC 6.4.1.3 from Ruegeria pomeroyi (strain ATCC 700808 / DSM 15171 / DSS-3) (Silicibacter pomeroyi) (see paper)
Q5LUF3 propionyl-CoA carboxylase (EC 6.4.1.3) from Ruegeria pomeroyi (see paper)
43% identity, 98% coverage of query (468 bits)
7ybuA / P05165 Human propionyl-coenzyme a carboxylase
42% identity, 99% coverage of query (466 bits)
PCCA / P05165 propionyl-CoA carboxylase α chain, mitochondrial (EC 6.4.1.3) from Homo sapiens (see 4 papers)
PCCA_HUMAN / P05165 Propionyl-CoA carboxylase alpha chain, mitochondrial; PCCase subunit alpha; Propanoyl-CoA:carbon dioxide ligase subunit alpha; EC 6.4.1.3 from Homo sapiens (Human) (see 11 papers)
P05165 propionyl-CoA carboxylase (subunit 1/2) (EC 6.4.1.3) from Homo sapiens (see paper)
42% identity, 99% coverage of query (464 bits)
Dshi_0723 Propionyl-CoA carboxylase biotin-containing subunit (EC 6.4.1.3) from Dinoroseobacter shibae DFL-12
43% identity, 98% coverage of query (464 bits)
Pcca / P14882 propionyl-CoA carboxylase α subunit (EC 6.4.1.3) from Rattus norvegicus (see paper)
42% identity, 99% coverage of query (463 bits)
3n6rG / Q5LUF3 Crystal structure of the holoenzyme of propionyl-coa carboxylase (pcc) (see paper)
42% identity, 98% coverage of query (449 bits)
8sgxX / A0A640KC69 Leishmania tarentolae propionyl-coa carboxylase (alpha-4-beta-6) (see paper)
41% identity, 99% coverage of query (447 bits)
Q9HPP8 biotin carboxylase (EC 6.3.4.14) from Halobacterium salinarum (see paper)
40% identity, 98% coverage of query (417 bits)
accC / A9W9X0 biotin carboxylase (EC 6.3.4.14) from Chloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl) (see paper)
A9W9X0 biotin carboxylase (EC 6.3.4.14) from Chloroflexus aurantiacus (see paper)
42% identity, 99% coverage of query (416 bits)
8hz4A / A9W9X0 The tetrameric structure of biotin carboxylase from chloroflexus aurantiacus in complex with bicarbonate
48% identity, 70% coverage of query (405 bits)
accC / Q877I5 acyl CoA carboxylase biotin carboxylase subunit (EC 2.1.3.15; EC 6.4.1.3; EC 6.3.4.14) from Acidianus brierleyi (see 2 papers)
Q877I5 biotin carboxylase (EC 6.3.4.14); acetyl-CoA carboxylase (subunit 2/3) (EC 6.4.1.2); propionyl-CoA carboxylase (subunit 1/3) (EC 6.4.1.3) from Acidianus brierleyi (see 2 papers)
accC / BAC55867.1 biotin carboxylase subunit of acetyl-CoA carboxylase from Acidianus brierleyi (see paper)
40% identity, 75% coverage of query (383 bits)
Build an alignment for Ac3H11_3016 and 30 homologs with ≥ 30% identity
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P11029 Acetyl-CoA carboxylase; ACC; EC 6.4.1.2; EC 6.3.4.14 from Gallus gallus (Chicken)
29% identity, 99% coverage of query (273 bits)
ACC1 / Q13085 acetyl-CoA carboxylase 1 (EC 2.1.3.15; EC 6.4.1.2; EC 6.3.4.14) from Homo sapiens (see 6 papers)
ACACA_HUMAN / Q13085 Acetyl-CoA carboxylase 1; ACC1; Acetyl-Coenzyme A carboxylase alpha; ACC-alpha; EC 6.4.1.2 from Homo sapiens (Human) (see 8 papers)
Q13085 acetyl-CoA carboxylase (EC 6.4.1.2) from Homo sapiens (see 13 papers)
29% identity, 99% coverage of query (272 bits)
ACACA_MOUSE / Q5SWU9 Acetyl-CoA carboxylase 1; ACC1; ACC-alpha; Acetyl-CoA carboxylase 265; EC 6.4.1.2 from Mus musculus (Mouse) (see 4 papers)
Q5SWU9 acetyl-CoA carboxylase (EC 6.4.1.2) from Mus musculus (see 2 papers)
29% identity, 99% coverage of query (271 bits)
ACAC_YEAST / Q00955 Acetyl-CoA carboxylase; ACC; Fatty acid synthetase 3; mRNA transport-defective protein 7; EC 6.4.1.2; EC 6.3.4.14 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 13 papers)
Q00955 biotin carboxylase (EC 6.3.4.14); acetyl-CoA carboxylase (EC 6.4.1.2) from Saccharomyces cerevisiae (see 6 papers)
28% identity, 98% coverage of query (269 bits)
ACAC_SCHPO / P78820 Acetyl-CoA carboxylase; ACC; Cell untimely torn protein 6; EC 6.4.1.2; EC 6.3.4.14 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see 2 papers)
cut6 / RF|NP_593271.1 acetyl-CoA/biotin carboxylase; EC 6.3.4.14 from Schizosaccharomyces pombe (see 2 papers)
29% identity, 98% coverage of query (268 bits)
ACACA_RAT / P11497 Acetyl-CoA carboxylase 1; ACC1; ACC-alpha; EC 6.4.1.2 from Rattus norvegicus (Rat) (see 4 papers)
29% identity, 99% coverage of query (263 bits)
5cslB / Q00955 Crystal structure of the 500 kd yeast acetyl-coa carboxylase holoenzyme dimer (see paper)
28% identity, 98% coverage of query (255 bits)
ACACB_MOUSE / E9Q4Z2 Acetyl-CoA carboxylase 2; ACC-beta; EC 6.4.1.2 from Mus musculus (Mouse) (see 10 papers)
29% identity, 96% coverage of query (249 bits)
5cslA / Q00955 Crystal structure of the 500 kd yeast acetyl-coa carboxylase holoenzyme dimer (see paper)
27% identity, 98% coverage of query (249 bits)
ACC2 / O00763 Biotin carboxylase (EC 2.1.3.15; EC 6.4.1.2; EC 6.3.4.14) from Homo sapiens (see 6 papers)
ACACB_HUMAN / O00763 Acetyl-CoA carboxylase 2; ACC-beta; EC 6.4.1.2 from Homo sapiens (Human) (see 12 papers)
O00763 biotin carboxylase (EC 6.3.4.14); acetyl-CoA carboxylase (EC 6.4.1.2) from Homo sapiens (see 11 papers)
29% identity, 96% coverage of query (242 bits)
ACC1 / Q38970 acetyl-CoA carboxylase 1 (EC 6.4.1.2) from Arabidopsis thaliana (see 2 papers)
ACC1_ARATH / Q38970 Acetyl-CoA carboxylase 1; AtACC1; Protein EMBRYO DEFECTIVE 22; Protein GURKE; Protein PASTICCINO 3; EC 6.4.1.2; EC 6.3.4.14 from Arabidopsis thaliana (Mouse-ear cress) (see 10 papers)
Q38970 acetyl-CoA carboxylase (EC 6.4.1.2) from Arabidopsis thaliana (see paper)
28% identity, 96% coverage of query (240 bits)
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Lawrence Berkeley National Laboratory