Searching for up to 100 curated homologs for Ac3H11_3309 FitnessBrowser__acidovorax_3H11:Ac3H11_3309 (548 a.a.)
Found high-coverage hits (≥70%) to 100 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
pdc / Q5NYJ8 phenylpyruvate decarboxylase (EC 4.1.1.43) from Aromatoleum aromaticum (strain EbN1) (see 2 papers)
59% identity, 99% coverage of query (620 bits)
2q5oA X-ray structure of phenylpyruvate decarboxylase in complex with 3- deaza-thdp and phenylpyruvate
58% identity, 97% coverage of query (580 bits)
ipdC / P51852 phenylpyruvate decarboxylase (EC 4.1.1.43) from Azospirillum brasilense (see 2 papers)
P51852 indolepyruvate decarboxylase (EC 4.1.1.74) from Azospirillum brasilense (see 2 papers)
57% identity, 98% coverage of query (577 bits)
2q5qA X-ray structure of phenylpyruvate decarboxylase in complex with 3- deaza-thdp and 5-phenyl-2-oxo-valeric acid
57% identity, 97% coverage of query (576 bits)
2q5lA / P51852 X-ray structure of phenylpyruvate decarboxylase in complex with 2-(1- hydroxyethyl)-3-deaza-thdp (see paper)
57% identity, 97% coverage of query (564 bits)
ipdC / CAA67899.1 indole-3-pyruvate decarboxylase from Azospirillum brasilense (see paper)
56% identity, 98% coverage of query (560 bits)
2nxwA Crystal structure of phenylpyruvate decarboxylase of azospirillum brasilense
57% identity, 97% coverage of query (557 bits)
2q5jA X-ray structure of phenylpyruvate decarboxylase in complex with 3- deaza-thdp
56% identity, 97% coverage of query (551 bits)
KDC_MYCTU / P9WG37 Alpha-keto-acid decarboxylase; KDC; EC 4.1.1.- from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
P9WG37 branched-chain-2-oxoacid decarboxylase (EC 4.1.1.72) from Mycobacterium tuberculosis (see paper)
32% identity, 95% coverage of query (191 bits)
Build an alignment for Ac3H11_3309 and 9 homologs with ≥ 30% identity
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Q9UUT6 pyruvate decarboxylase (EC 4.1.1.1) from Zygosaccharomyces bisporus (see paper)
26% identity, 99% coverage of query (184 bits)
PDC1_CANGA / Q6FJA3 Pyruvate decarboxylase; EC 4.1.1.1 from Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138) (Yeast) (Nakaseomyces glabratus) (see paper)
27% identity, 96% coverage of query (182 bits)
Q12629 pyruvate decarboxylase (EC 4.1.1.1) from Kluyveromyces lactis (see paper)
26% identity, 99% coverage of query (181 bits)
2vjyA / Q12629 Pyruvate decarboxylase from kluyveromyces lactis in complex with the substrate analogue methyl acetylphosphonate (see paper)
26% identity, 99% coverage of query (181 bits)
PDC1_CANAL / P83779 Pyruvate decarboxylase; EC 4.1.1.1 from Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) (see paper)
PDC11 pyruvate decarboxylase from Candida albicans (see 5 papers)
27% identity, 96% coverage of query (181 bits)
PDC5 / P16467 pyruvate decarboxylase 2 monomer (EC 4.1.1.1; EC 4.1.1.43; EC 4.1.1.74; EC 4.1.1.72) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see 8 papers)
PDC5_YEAST / P16467 Pyruvate decarboxylase isozyme 2; Thiamine pyrophosphate-dependent 2-oxo-acid decarboxylase; 2ODC; EC 4.1.1.-; EC 4.1.1.43; EC 4.1.1.72; EC 4.1.1.74 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 15 papers)
P16467 pyruvate decarboxylase (EC 4.1.1.1) from Saccharomyces cerevisiae (see 2 papers)
26% identity, 99% coverage of query (180 bits)
6efhA Pyruvate decarboxylase from kluyveromyces lactis soaked with pyruvamide
26% identity, 97% coverage of query (180 bits)
PDC13 / AAP75899.1 pyruvate decarboxylase from Lachancea kluyveri (see paper)
26% identity, 99% coverage of query (179 bits)
2vbfB / Q6QBS4 The holostructure of the branched-chain keto acid decarboxylase (kdca) from lactococcus lactis (see paper)
26% identity, 97% coverage of query (177 bits)
2vbgA The complex structure of the branched-chain keto acid decarboxylase (kdca) from lactococcus lactis with 2r-1-hydroxyethyl-deazathdp
26% identity, 97% coverage of query (177 bits)
5npuA Inferred ancestral pyruvate decarboxylase (see paper)
28% identity, 99% coverage of query (176 bits)
6vgsBBB / A0A0B8QZ66 6vgsBBB (see paper)
25% identity, 97% coverage of query (176 bits)
PDC1 / P06169 pyruvate decarboxylase (EC 4.1.1.1; EC 4.1.1.80; EC 4.1.1.43; EC 4.1.1.74; EC 4.1.1.72) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see 8 papers)
PDC1_YEAST / P06169 Pyruvate decarboxylase isozyme 1; Thiamine pyrophosphate-dependent 2-oxo-acid decarboxylase; 2ODC; EC 4.1.1.-; EC 4.1.1.43; EC 4.1.1.72; EC 4.1.1.74 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 20 papers)
P06169 pyruvate decarboxylase (EC 4.1.1.1) from Saccharomyces cerevisiae (see 4 papers)
25% identity, 96% coverage of query (175 bits)
A0A125STX6 pyruvate decarboxylase (EC 4.1.1.1) from Phanerochaete sordida (see paper)
28% identity, 86% coverage of query (174 bits)
Q2UKV4 phenylpyruvate decarboxylase (EC 4.1.1.43) from Aspergillus oryzae (see paper)
27% identity, 96% coverage of query (174 bits)
1qpbA Pyruvate decarboyxlase from yeast (form b) complexed with pyruvamide
25% identity, 96% coverage of query (173 bits)
kivD / Q684J7 α-ketoisovalerate decarboxylase subunit (EC 4.1.1.72) from Lactococcus lactis subsp. lactis (see 2 papers)
Q684J7 pyruvate decarboxylase (EC 4.1.1.1); branched-chain-2-oxoacid decarboxylase (EC 4.1.1.72) from Lactococcus lactis subsp. lactis (see 6 papers)
25% identity, 97% coverage of query (172 bits)
1ovmA / P23234 Crystal structure of indolepyruvate decarboxylase from enterobacter cloacae (see paper)
27% identity, 97% coverage of query (171 bits)
C4R3T2 pyruvate decarboxylase (EC 4.1.1.1) from Komagataella pastoris (see paper)
26% identity, 97% coverage of query (169 bits)
THI3 / Q07471 keto-isocaproate decarboxylase subunit (EC 4.1.1.72) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see 4 papers)
THI3_YEAST / Q07471 Thiamine metabolism regulatory protein THI3; Keto isocaproate decarboxylase 1; Thiamine pyrophosphate-dependent 2-oxo-acid decarboxylase; 2ODC; EC 4.1.1.72 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 8 papers)
Q07471 branched-chain-2-oxoacid decarboxylase (EC 4.1.1.72) from Saccharomyces cerevisiae (see 2 papers)
24% identity, 95% coverage of query (169 bits)
V6RPS5 pyruvate decarboxylase (EC 4.1.1.1) from Fusarium graminearum (see paper)
26% identity, 95% coverage of query (168 bits)
PDC4_SCHPO / O42873 Putative pyruvate decarboxylase C3G9.11c; EC 4.1.1.1 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
27% identity, 95% coverage of query (168 bits)
8hp4A / C5MDS4 Ctpdc complex
26% identity, 96% coverage of query (167 bits)
2vk1A / P06169 Crystal structure of the saccharomyces cerevisiae pyruvate decarboxylase variant d28a in complex with its substrate (see paper)
25% identity, 96% coverage of query (167 bits)
ipdC / P23234 indole-3-pyruvate decarboxylase subunit (EC 4.1.1.74) from Enterobacter cloacae (see 2 papers)
DCIP_ENTCL / P23234 Indole-3-pyruvate decarboxylase; Indolepyruvate decarboxylase; EC 4.1.1.74 from Enterobacter cloacae (see paper)
P23234 indolepyruvate decarboxylase (EC 4.1.1.74) from Enterobacter cloacae (see paper)
27% identity, 97% coverage of query (166 bits)
PDC6 / P26263 pyruvate decarboxylase 3 monomer (EC 4.1.1.1; EC 4.1.1.80; EC 4.1.1.43; EC 4.1.1.74; EC 4.1.1.72) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see 9 papers)
PDC6_YEAST / P26263 Pyruvate decarboxylase isozyme 3; Thiamine pyrophosphate-dependent 2-oxo-acid decarboxylase; 2ODC; EC 4.1.1.-; EC 4.1.1.43; EC 4.1.1.72; EC 4.1.1.74 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 13 papers)
P26263 pyruvate decarboxylase (EC 4.1.1.1) from Saccharomyces cerevisiae (see 2 papers)
26% identity, 99% coverage of query (165 bits)
PDC12 / AAP75898.1 pyruvate decarboxylase from Lachancea kluyveri (see paper)
25% identity, 99% coverage of query (164 bits)
C7JF72 pyruvate decarboxylase (EC 4.1.1.1) from Acetobacter pasteurianus (see paper)
25% identity, 99% coverage of query (164 bits)
2w93A Crystal structure of the saccharomyces cerevisiae pyruvate decarboxylase variant e477q in complex with the surrogate pyruvamide
25% identity, 96% coverage of query (162 bits)
Q92345 Probable pyruvate decarboxylase C1F8.07c; EC 4.1.1.1 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
26% identity, 99% coverage of query (161 bits)
2vbiA / Q8L388 Holostructure of pyruvate decarboxylase from acetobacter pasteurianus
25% identity, 99% coverage of query (160 bits)
Q659I2 pyruvate decarboxylase (EC 4.1.1.1) from Wickerhamomyces anomalus (see paper)
27% identity, 85% coverage of query (159 bits)
Q93EN4 pyruvate decarboxylase (EC 4.1.1.1) from Sarcina ventriculi (see paper)
25% identity, 96% coverage of query (158 bits)
6efgD / Q12629 Pyruvate decarboxylase from kluyveromyces lactis
25% identity, 97% coverage of query (158 bits)
A0A068LJY3 pyruvate decarboxylase (subunit 2/3) (EC 4.1.1.1) from Hevea brasiliensis (see paper)
25% identity, 99% coverage of query (157 bits)
Q8L388 pyruvate decarboxylase (EC 4.1.1.1) from Acetobacter pasteurianus (see paper)
25% identity, 99% coverage of query (156 bits)
PDC1 / P51850 pyruvate decarboxylase (EC 4.1.1.1) from Pisum sativum (see paper)
26% identity, 99% coverage of query (154 bits)
A0A068LJJ5 pyruvate decarboxylase (subunit 3/3) (EC 4.1.1.1) from Hevea brasiliensis (see paper)
25% identity, 99% coverage of query (151 bits)
PDC4_ARATH / Q9M040 Pyruvate decarboxylase 4; AtPDC4; EC 4.1.1.1 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
Q9M040 pyruvate decarboxylase (EC 4.1.1.1) from Arabidopsis thaliana (see paper)
25% identity, 99% coverage of query (146 bits)
PDC3_ARATH / Q9M039 Pyruvate decarboxylase 3; AtPDC3; EC 4.1.1.1 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
Q9M039 pyruvate decarboxylase (EC 4.1.1.1) from Arabidopsis thaliana (see paper)
25% identity, 99% coverage of query (144 bits)
Q8KTX6 pyruvate decarboxylase (EC 4.1.1.1) from Zymobacter palmae (see paper)
24% identity, 100% coverage of query (142 bits)
PDC2_ARATH / Q9FFT4 Pyruvate decarboxylase 2; AtPDC2; EC 4.1.1.1 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
Q9FFT4 pyruvate decarboxylase (EC 4.1.1.1) from Arabidopsis thaliana (see 2 papers)
25% identity, 99% coverage of query (142 bits)
5eujE / Q8KTX6 5eujE (see paper)
24% identity, 100% coverage of query (142 bits)
PDC1_ARATH / O82647 Pyruvate decarboxylase 1; AtPDC1; EC 4.1.1.1 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
O82647 pyruvate decarboxylase (EC 4.1.1.1) from Arabidopsis thaliana (see paper)
24% identity, 99% coverage of query (141 bits)
ipdC / P71323 indolepyruvate decarboxylase subunit (EC 4.1.1.74) from Enterobacter agglomerans (see paper)
27% identity, 97% coverage of query (139 bits)
A0A068LQF7 pyruvate decarboxylase (EC 4.1.1.1) from Hevea brasiliensis (see paper)
25% identity, 99% coverage of query (138 bits)
A0A068LJB0 pyruvate decarboxylase (subunit 1/3) (EC 4.1.1.1) from Hevea brasiliensis (see paper)
26% identity, 99% coverage of query (137 bits)
B0ZS79 pyruvate decarboxylase (EC 4.1.1.1) from Prunus armeniaca (see paper)
24% identity, 99% coverage of query (134 bits)
1zpdA Pyruvate decarboxylase from zymomonas mobilis
24% identity, 99% coverage of query (134 bits)
pdc / P06672 pyruvate decarboxylase monomer (EC 4.1.1.1) from Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4) (see paper)
P06672 pyruvate decarboxylase (EC 4.1.1.1) from Zymomonas mobilis (see 5 papers)
24% identity, 99% coverage of query (133 bits)
2wvgA Structural insights into the pre-reaction state of pyruvate decarboxylase from zymomonas mobilis
24% identity, 99% coverage of query (133 bits)
2wvaE Structural insights into the pre-reaction state of pyruvate decarboxylase from zymomonas mobilis
24% identity, 99% coverage of query (133 bits)
2wvaA Structural insights into the pre-reaction state of pyruvate decarboxylase from zymomonas mobilis
24% identity, 99% coverage of query (133 bits)
P06672 Pyruvate decarboxylase; PDC; EC 4.1.1.1 from Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4)
24% identity, 99% coverage of query (133 bits)
3oe1A Pyruvate decarboxylase variant glu473asp from z. Mobilis in complex with reaction intermediate 2-lactyl-thdp
24% identity, 99% coverage of query (133 bits)
D9J047 pyruvate dehydrogenase system (EC 1.2.1.104); pyruvate decarboxylase (EC 4.1.1.1) from Zymomonas mobilis (see paper)
24% identity, 99% coverage of query (130 bits)
ARO10 / Q06408 2-keto-3-methylvalerate decarboxylase subunit (EC 4.1.1.1; EC 4.1.1.74; EC 4.1.1.43; EC 4.1.1.72) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see 5 papers)
ARO10_YEAST / Q06408 Transaminated amino acid decarboxylase; Thiamine diphosphate-dependent phenylpyruvate decarboxylase; PPDC; Thiamine pyrophosphate-dependent 2-oxo-acid decarboxylase; 2ODC; Transaminated branched-chain amino acid decarboxylase; EC 4.1.1.-; EC 4.1.1.43; EC 4.1.1.72; EC 4.1.1.74; EC 4.1.1.80 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 8 papers)
Q06408 phenylpyruvate decarboxylase (EC 4.1.1.43) from Saccharomyces cerevisiae (see paper)
23% identity, 89% coverage of query (129 bits)
P37251 acetolactate synthase (EC 2.2.1.6) from Bacillus subtilis (see paper)
26% identity, 90% coverage of query (125 bits)
Q8U2A4 acetolactate synthase (EC 2.2.1.6) from Pyrococcus furiosus (see paper)
27% identity, 91% coverage of query (125 bits)
5tmaA / P06672 Zymomonas mobilis pyruvate decarboxylase mutant pdc-2.3 (see paper)
24% identity, 99% coverage of query (124 bits)
A0A075Q354 pyruvate decarboxylase (EC 4.1.1.1) from Gluconacetobacter diazotrophicus (see paper)
26% identity, 99% coverage of query (123 bits)
A9H275 pyruvate decarboxylase (EC 4.1.1.1) from Gluconacetobacter diazotrophicus (see paper)
26% identity, 97% coverage of query (122 bits)
Q8RL88 acetolactate synthase (subunit 2/2) (EC 2.2.1.6) from Geobacillus stearothermophilus (see paper)
ilvB / AAL99356.1 acetohydroxy acid synthase large subunit from Geobacillus stearothermophilus (see paper)
27% identity, 93% coverage of query (122 bits)
4cokB / A9H275 Functional and structural characterization of pyruvate decarboxylase from gluconoacetobacter diazotrophicus (see paper)
26% identity, 99% coverage of query (122 bits)
6lpiB / P08142 Crystal structure of ahas holo-enzyme (see paper)
27% identity, 84% coverage of query (119 bits)
IlvB / b3671 acetohydroxy acid synthase I subunit IlvB (EC 2.2.1.6) from Escherichia coli K-12 substr. MG1655 (see 7 papers)
ilvB / P08142 acetohydroxy acid synthase I subunit IlvB (EC 2.2.1.6) from Escherichia coli (strain K12) (see 4 papers)
P08142 acetolactate synthase (subunit 2/2) (EC 2.2.1.6) from Escherichia coli (see paper)
27% identity, 84% coverage of query (119 bits)
P45261 acetolactate synthase (EC 2.2.1.6) from Haemophilus influenzae (see paper)
23% identity, 94% coverage of query (116 bits)
1t9cA Crystal structure of yeast acetohydroxyacid synthase in complex with a sulfonylurea herbicide, sulfometuron methyl
25% identity, 90% coverage of query (115 bits)
1t9dA Crystal structure of yeast acetohydroxyacid synthase in complex with a sulfonylurea herbicide, metsulfuron methyl
25% identity, 90% coverage of query (115 bits)
1t9aA Crystal structure of yeast acetohydroxyacid synthase in complex with a sulfonylurea herbicide, tribenuron methyl
25% identity, 90% coverage of query (115 bits)
ilvB / O08353 acetohydroxy-acid synthase large subunit (EC 2.2.1.6) from Methanococcus aeolicus (see 2 papers)
23% identity, 91% coverage of query (114 bits)
ILVB_YEAST / P07342 Acetolactate synthase catalytic subunit, mitochondrial; Acetohydroxy-acid synthase catalytic subunit; AHAS; ALS; EC 2.2.1.6 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 2 papers)
P07342 acetolactate synthase (EC 2.2.1.6) from Saccharomyces cerevisiae (see 5 papers)
25% identity, 90% coverage of query (114 bits)
1t9bA / P07342 Crystal structure of yeast acetohydroxyacid synthase in complex with a sulfonylurea herbicide, chlorsulfuron (see paper)
25% identity, 90% coverage of query (113 bits)
6u9dB / P07342 Saccharomyces cerevisiae acetohydroxyacid synthase (see paper)
25% identity, 90% coverage of query (113 bits)
1t9dB Crystal structure of yeast acetohydroxyacid synthase in complex with a sulfonylurea herbicide, metsulfuron methyl
25% identity, 90% coverage of query (113 bits)
1t9bB Crystal structure of yeast acetohydroxyacid synthase in complex with a sulfonylurea herbicide, chlorsulfuron
25% identity, 90% coverage of query (111 bits)
1n0hA Crystal structure of yeast acetohydroxyacid synthase in complex with a sulfonylurea herbicide, chlorimuron ethyl
25% identity, 90% coverage of query (111 bits)
5wkcA Saccharomyces cerevisiae acetohydroxyacid synthase in complex with the herbicide penoxsulam
25% identity, 90% coverage of query (110 bits)
6bd3A Saccharomyces cerevisiae acetohydroxyacid synthase
25% identity, 90% coverage of query (109 bits)
6bd9A Saccharomyces cerevisiae acetohydroxyacid synthase
25% identity, 90% coverage of query (107 bits)
5imsA Saccharomyces cerevisiae acetohydroxyacid synthase
25% identity, 90% coverage of query (107 bits)
1jscA Crystal structure of the catalytic subunit of yeast acetohydroxyacid synthase: a target for herbicidal inhibitors
25% identity, 90% coverage of query (106 bits)
6dekA Crystal structure of candida albicans acetohydroxyacid synthase catalytic subunit
24% identity, 94% coverage of query (105 bits)
6wo1A / Q96VZ6 Hybrid acetohydroxyacid synthase complex structure with cryptococcus neoformans ahas catalytic subunit and saccharomyces cerevisiae ahas regulatory subunit (see paper)
26% identity, 81% coverage of query (104 bits)
6deqA / A0A1D8PJF9 Crystal structure of candida albicans acetohydroxyacid synthase in complex with the herbicide penoxsulam (see paper)
23% identity, 94% coverage of query (103 bits)
7egvA / A0A2N1LPC4 Acetolactate synthase from trichoderma harzianum with inhibitor harzianic acid (see paper)
26% identity, 89% coverage of query (103 bits)
6derA Crystal structure of candida albicans acetohydroxyacid synthase in complex with the herbicide metosulam
23% identity, 94% coverage of query (101 bits)
6desA Crystal structure of candida albicans acetohydroxyacid synthase in complex with the herbicide propoxycarbazone
23% identity, 94% coverage of query (101 bits)
6depA Crystal structure of candida albicans acetohydroxyacid synthase in complex with the herbicide sulfometuron methyl
23% identity, 94% coverage of query (101 bits)
6deoA Crystal structure of candida albicans acetohydroxyacid synthase in complex with the herbicide iodomuron methyl
23% identity, 94% coverage of query (101 bits)
6denA Crystal structure of candida albicans acetohydroxyacid synthase in complex with the herbicide iodomuron ethyl
23% identity, 94% coverage of query (100 bits)
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