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Searching for up to 100 curated homologs for Ac3H11_3317 FitnessBrowser__acidovorax_3H11:Ac3H11_3317 (213 a.a.)

Found high-coverage hits (≥70%) to 100 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

ndmE / R9TPE4 glutathione-S-transferase NdmE (EC 1.14.13.128) from Pseudomonas putida (see paper)
    30% identity, 95% coverage of query (105 bits)

3m3mA / Q4K8I0 Crystal structure of glutathione s-transferase from pseudomonas fluorescens [pf-5]
    36% identity, 89% coverage of query (103 bits)

4gsnB / Q9GPL8 Crystal structure of gste2 zan/u variant from anopheles gambiae (see paper)
    32% identity, 90% coverage of query (100 bits)

Q7PVS6 glutathione transferase (EC 2.5.1.18) from Anopheles gambiae (see paper)
    32% identity, 90% coverage of query (100 bits)

2imkA Structures of an insect epsilon-class glutathione s-transferase from the malaria vector anopheles gambiae: evidence for high ddt- detoxifying activity
    32% identity, 90% coverage of query (100 bits)

4hz2B / A7ILT8 Crystal structure of glutathione s-transferase xaut_3756 (target efi- 507152) from xanthobacter autotrophicus py2
    33% identity, 90% coverage of query (99.0 bits)

3zmkB / G0XSZ1 Anopheles funestus glutathione-s-transferase epsilon 2 (gste2) protein structure from different alelles: a single amino acid change confers high level of ddt resistance and cross resistance to permethrin in a major malaria vector in africa (see paper)
    31% identity, 91% coverage of query (95.9 bits)

Q2YFE3 glutathione transferase (EC 2.5.1.18) from Dermatophagoides pteronyssinus (see paper)
    31% identity, 89% coverage of query (95.1 bits)

GST1B_ANOGA / O77473 Glutathione S-transferase 1, isoform B; AgGst1-alpha; Aggst1-4; GST class-theta; EC 2.5.1.18 from Anopheles gambiae (African malaria mosquito) (see paper)
    30% identity, 89% coverage of query (92.4 bits)

5ft3B / Q5PY77 Aedes aegypti gste2
    34% identity, 98% coverage of query (92.0 bits)

A1ZB72 glutathione transferase (EC 2.5.1.18) from Drosophila melanogaster (see paper)
4pngB / A1ZB72 Glutathione s-transferase from drosophila melanogaster - isozyme e7 (see paper)
    31% identity, 90% coverage of query (91.3 bits)

Build an alignment

Build an alignment for Ac3H11_3317 and 11 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

GST1D_ANOGA / Q93113 Glutathione S-transferase 1, isoform D; AgGst1-alpha; Aggst1-1; Aggst1-6; Aggst2-1; DDT-dehydrochlorinase; GST class-theta; EC 2.5.1.18; EC 4.5.1.1 from Anopheles gambiae (African malaria mosquito) (see 3 papers)
1pn9A / Q93113 Crystal structure of an insect delta-class glutathione s-transferase from a ddt-resistant strain of the malaria vector anopheles gambiae (see paper)
GSTd1-6 / CAB03593.1 GSTD1-6 protein, partial from Anopheles gambiae (see 2 papers)
    28% identity, 90% coverage of query (90.5 bits)

gst3b / CAB38119.1 Glutathione transferase III(b) from Zea mays (see paper)
    34% identity, 91% coverage of query (89.0 bits)

GSTEE_DROME / Q7JYX0 Glutathione S-transferase E14; Protein noppera-bo; EC 2.5.1.18 from Drosophila melanogaster (Fruit fly) (see 3 papers)
    33% identity, 83% coverage of query (88.6 bits)

6t2tA / Q7JYX0 Crystal structure of drosophila melanogaster glutathione s-transferase epsilon 14 in complex with glutathione and 2-methyl-2,4-pentanediol (see paper)
    33% identity, 83% coverage of query (88.2 bits)

gst3a / CAB38118.1 Glutathione transferase III(a) from Zea mays (see paper)
    34% identity, 91% coverage of query (88.2 bits)

1jlvA / Q7KIF2 Anopheles dirus species b glutathione s-transferases 1-3 (see paper)
    29% identity, 88% coverage of query (87.0 bits)

Q8N0B3 glutathione transferase (EC 2.5.1.18) from Nilaparvata lugens (see paper)
    30% identity, 91% coverage of query (86.7 bits)

3wywB / Q8N0B3 Structural characterization of catalytic site of a nilaparvata lugens delta-class glutathione transferase (see paper)
    30% identity, 91% coverage of query (86.7 bits)

3vwxC / Q9U795 Structural analysis of an epsilon-class glutathione s-transferase from housefly, musca domestica (see paper)
    30% identity, 83% coverage of query (85.9 bits)

7daxA Crystal structure of drosophila melanogaster noppera-bo, glutathione s-transferase epsilon 14 (dmgste14), in tdp013-bound form
    32% identity, 83% coverage of query (85.9 bits)

7db3A Crystal structure of drosophila melanogaster noppera-bo, glutathione s-transferase epsilon 14 (dmgste14), in tdp011-bound form
    32% identity, 83% coverage of query (85.9 bits)

7db4A Crystal structure of drosophila melanogaster noppera-bo, glutathione s-transferase epsilon 14 (dmgste14), in tdp012- and glutathione-bound form
    32% identity, 83% coverage of query (85.9 bits)

7dazA Crystal structure of drosophila melanogaster noppera-bo, glutathione s-transferase epsilon 14 (dmgste14), in tdp015- and gsh-bound form
    32% identity, 83% coverage of query (85.9 bits)

6keoAA Glutathione S-transferase E14
    32% identity, 83% coverage of query (85.9 bits)

7db0A Crystal structure of drosophila melanogaster noppera-bo, glutathione s-transferase epsilon 14 (dmgste14), in dimedone-bound form
    32% identity, 83% coverage of query (85.9 bits)

G8F1C9 glutathione transferase (EC 2.5.1.18) from Macaca mulatta (see paper)
A0A023JCN4 glutathione transferase (EC 2.5.1.18) from Macaca fascicularis (see paper)
    28% identity, 90% coverage of query (85.5 bits)

4mpgB / P0CG30 Crystal structure of human glutathione transferase theta-2, complex with glutathione and unknown ligand, target efi-507257
    30% identity, 79% coverage of query (84.7 bits)

Q9U795 glutathione transferase (EC 2.5.1.18) from Musca domestica (see paper)
    30% identity, 83% coverage of query (84.7 bits)

GST2_HUMAN / P0CG29 Glutathione S-transferase theta-2; GST class-theta-2; EC 2.5.1.18 from Homo sapiens (Human) (see 2 papers)
    30% identity, 79% coverage of query (84.7 bits)

8ai8A / Q55139 Crystal structure of glutathione transferase chi 1 from synechocystis sp. Pcc 6803 in complex with glutathione (see paper)
    33% identity, 90% coverage of query (84.3 bits)

GSTT2_HUMAN / P0CG30 Glutathione S-transferase theta-2B; Glutathione S-transferase theta-2; GST class-theta-2; EC 2.5.1.18 from Homo sapiens (Human) (see 3 papers)
P0CG30 glutathione transferase (EC 2.5.1.18) from Homo sapiens (see paper)
    30% identity, 79% coverage of query (84.3 bits)

GSTD3_DROME / Q9VG97 Inactive glutathione S-transferase D3 from Drosophila melanogaster (Fruit fly) (see paper)
    27% identity, 80% coverage of query (84.3 bits)

7pkaA Synechocystis sp. Pcc6803 glutathione transferase chi 1, gsoh bound
    33% identity, 90% coverage of query (84.3 bits)

3ljrA Glutathione transferase (theta class) from human in complex with the glutathione conjugate of 1-menaphthyl sulfate
    30% identity, 79% coverage of query (84.3 bits)

3f63A / Q9GN60 Crystal structure of a delta class gst (adgstd4-4) from anopheles dirus, in complex with s-hexyl glutathione (see paper)
    30% identity, 90% coverage of query (84.0 bits)

Q9GN60 glutathione transferase (EC 2.5.1.18) from Anopheles dirus (see 2 papers)
    30% identity, 90% coverage of query (84.0 bits)

4pnfB / Q7JZM3 Glutathione s-transferase from drosophila melanogaster - isozyme e6 (see paper)
    30% identity, 90% coverage of query (83.6 bits)

7rhpA / A0A7M7GUY7 Crystal structure of honeybee (apis mellifera) glutathione s- transferase amgstd1 (see paper)
    27% identity, 91% coverage of query (83.6 bits)

Q8DMB4 glutathione transferase (EC 2.5.1.18) from Thermosynechococcus vestitus (see paper)
    36% identity, 80% coverage of query (83.6 bits)

Q8GTB8 glutathione transferase (EC 2.5.1.18) from Triticum aestivum (see paper)
    29% identity, 94% coverage of query (82.0 bits)

Q5ISV1 glutathione transferase (EC 2.5.1.18) from Sarcoptes scabiei (see 2 papers)
    33% identity, 88% coverage of query (82.0 bits)

GST1C_ANOGA / Q93112 Glutathione S-transferase 1, isoform C; AgGst1-alpha; Aggst1-5; DDT-dehydrochlorinase; GST class-theta; EC 2.5.1.18; EC 4.5.1.1 from Anopheles gambiae (African malaria mosquito) (see paper)
    26% identity, 88% coverage of query (82.0 bits)

3g7iB Crystal structure of a delta class gst (adgstd4-4) from anopheles dirus, with glutathione complexed in one subunit
    30% identity, 90% coverage of query (81.3 bits)

GSTd1-5 / CAB03592.1 GSTD1-5 protein from Anopheles gambiae (see 2 papers)
    25% identity, 88% coverage of query (80.1 bits)

1r5aA / Q9GQG7 Glutathione s-transferase (see paper)
    28% identity, 87% coverage of query (78.2 bits)

A0A023JCR6 glutathione transferase (EC 2.5.1.18) from Macaca mulatta (see paper)
    31% identity, 90% coverage of query (78.2 bits)

5zwpA / P28338 Crystal structure of the delta-class glutathione transferase from musca domestica (see paper)
    26% identity, 90% coverage of query (78.2 bits)

P42860 glutathione transferase (EC 2.5.1.18) from Lucilia cuprina (see paper)
    26% identity, 90% coverage of query (78.2 bits)

4e8hB / O61996 Structural of bombyx mori glutathione transferase bmgstd1 complex with gtt
    26% identity, 91% coverage of query (77.8 bits)

GSTT1_MOUSE / Q64471 Glutathione S-transferase theta-1; GST class-theta-1; EC 2.5.1.18 from Mus musculus (Mouse) (see paper)
    29% identity, 90% coverage of query (77.4 bits)

GSTD2_DROME / Q9VG98 Glutathione S-transferase D2; EC 2.5.1.18 from Drosophila melanogaster (Fruit fly) (see paper)
Q9VG98 glutathione transferase (EC 2.5.1.18) from Drosophila melanogaster (see paper)
    27% identity, 90% coverage of query (77.0 bits)

GSTT1_RAT / Q01579 Glutathione S-transferase theta-1; GST 5-5; GST class-theta-1; Glutathione S-transferase 5; EC 2.5.1.18 from Rattus norvegicus (Rat) (see 2 papers)
    29% identity, 90% coverage of query (76.6 bits)

GST1 / AAA29287.1 glutathione transferase from Lucilia cuprina (see paper)
    26% identity, 90% coverage of query (76.6 bits)

Q60GK5 glutathione transferase (EC 2.5.1.18) from Bombyx mori (see paper)
    27% identity, 90% coverage of query (76.6 bits)

A0A023JCC0 glutathione transferase (EC 2.5.1.18) from Macaca fascicularis (see paper)
    30% identity, 90% coverage of query (76.3 bits)

GSTD4_DROME / Q9VG96 Glutathione S-transferase D4; EC 2.5.1.18 from Drosophila melanogaster (Fruit fly) (see paper)
    26% identity, 90% coverage of query (76.3 bits)

GSTT1_HUMAN / P30711 Glutathione S-transferase theta-1; GST class-theta-1; Glutathione transferase T1-1; EC 2.5.1.18 from Homo sapiens (Human) (see 4 papers)
P30711 glutathione transferase (EC 2.5.1.18) from Homo sapiens (see 4 papers)
    30% identity, 90% coverage of query (75.9 bits)

2c3qA / P30711 Human glutathione-s-transferase t1-1 w234r mutant, complex with s- hexylglutathione (see paper)
    30% identity, 90% coverage of query (75.9 bits)

3gh6A / Q9VGA1 Crystal structure of glutathione transferase dmgstd10 from drosophila melanogaster, in complex with glutathione (see paper)
    27% identity, 90% coverage of query (75.9 bits)

GSTD5_DROME / Q9VG95 Glutathione S-transferase D5; EC 2.5.1.18 from Drosophila melanogaster (Fruit fly) (see paper)
    26% identity, 90% coverage of query (75.9 bits)

4i97A / R4S8C5 The crystal structure of glutathione s-transferase sniggstd1a from scaptomyza nigrita in complex with glutathione
    26% identity, 90% coverage of query (75.5 bits)

4hi7A / B4KM86 Crystal structure of glutathione transferase homolog from drosophilia mojavensis, target efi-501819, with bound glutathione
    28% identity, 89% coverage of query (75.1 bits)

Q2YFE6 glutathione transferase (EC 2.5.1.18) from Sarcoptes scabiei (see paper)
    29% identity, 86% coverage of query (75.1 bits)

A0T2X7 glutathione transferase (EC 2.5.1.18) from Vitis vinifera (see paper)
    29% identity, 90% coverage of query (74.3 bits)

A6MN06 glutathione transferase (EC 2.5.1.18) from Alitta succinea (see paper)
    29% identity, 88% coverage of query (73.9 bits)

HPM2_HYPSB / B3FWR8 Glutathione S-transferase hmp2; Hypothemycin biosynthesis cluster protein hpm2; EC 2.5.1.18 from Hypomyces subiculosus (Nectria subiculosa) (see 10 papers)
    29% identity, 82% coverage of query (73.9 bits)

GSTF1_ORYSJ / O65857 Probable glutathione S-transferase GSTF1; GST-I; EC 2.5.1.18 from Oryza sativa subsp. japonica (Rice)
    28% identity, 93% coverage of query (72.8 bits)

GSTT2_MOUSE / Q61133 Glutathione S-transferase theta-2; GST class-theta-2; EC 2.5.1.18 from Mus musculus (Mouse) (see paper)
    30% identity, 79% coverage of query (72.8 bits)

GSTT2_RAT / P30713 Glutathione S-transferase theta-2; GST 12-12; GST class-theta-2; Glutathione S-transferase 12; Glutathione S-transferase Yrs-Yrs; EC 2.5.1.18 from Rattus norvegicus (Rat) (see 2 papers)
    30% identity, 79% coverage of query (72.0 bits)

Q8LGN5 glutathione transferase (EC 2.5.1.18) from Triticum aestivum (see paper)
    27% identity, 94% coverage of query (72.0 bits)

GSTT2_ANOGA / Q94999 Glutathione S-transferase 2; Aggst1-2; GST class-theta; EC 2.5.1.18 from Anopheles gambiae (African malaria mosquito) (see paper)
    26% identity, 90% coverage of query (72.0 bits)

4mf6A / B1FXZ2 Crystal structure of glutathione transferase bgramdraft_1843 from burkholderia graminis, target efi-507289, with two glutathione molecules bound per one protein subunit
    30% identity, 77% coverage of query (71.6 bits)

GSTD7_DROME / Q9VG93 Glutathione S-transferase D7; EC 2.5.1.18 from Drosophila melanogaster (Fruit fly) (see paper)
    25% identity, 90% coverage of query (71.2 bits)

GSTD6_DROME / Q9VG94 Glutathione S-transferase D6; EC 2.5.1.18 from Drosophila melanogaster (Fruit fly) (see paper)
    27% identity, 90% coverage of query (71.2 bits)

GSTD1_DROME / P20432 Glutathione S-transferase D1; DDT-dehydrochlorinase; EC 2.5.1.18; EC 4.5.1.1 from Drosophila melanogaster (Fruit fly) (see 2 papers)
    25% identity, 90% coverage of query (70.9 bits)

3makA / P20432 Crystal structure of glutathione transferase dmgstd1 from drosophila melanogaster, in complex with glutathione (see paper)
    25% identity, 90% coverage of query (70.9 bits)

GSTT3_MOUSE / Q99L20 Glutathione S-transferase theta-3; EC 2.5.1.18 from Mus musculus (Mouse) (see paper)
    28% identity, 90% coverage of query (70.9 bits)

4nhzH / A5EI34 Crystal structure of glutathione transferase bbta-3750 from bradyrhizobium sp., Target efi-507290, with one glutathione bound
    28% identity, 89% coverage of query (70.5 bits)

CH_124240 putative glutathione S-transferase [Botryotinia fuckeliana] from Magnaporthe grisea 70-15 (see paper)
    26% identity, 84% coverage of query (70.5 bits)

4f0bA / I7A570 Crystal structure of the glutathione transferase ure2p1 from phanerochaete chrysosporium. (see paper)
    26% identity, 82% coverage of query (70.1 bits)

Q8GRI3 glutathione transferase (EC 2.5.1.18) from Triticum aestivum (see paper)
    27% identity, 94% coverage of query (70.1 bits)

GSTF1_TOBAC / P30109 Glutathione S-transferase PARB; GST class-phi; EC 2.5.1.18 from Nicotiana tabacum (Common tobacco) (see paper)
    27% identity, 90% coverage of query (69.7 bits)

nagL / O86043 glutathion-dependent maleylpyruvate isomerase (EC 5.2.1.4) from Ralstonia sp. (see paper)
NAGL_RALSP / O86043 Maleylpyruvate isomerase; MPI; Naphthalene degradation protein L; EC 5.2.1.4 from Ralstonia sp. (see 2 papers)
    33% identity, 85% coverage of query (69.7 bits)

2jl4A Holo structure of maleyl pyruvate isomerase, a bacterial glutathione- s-transferase in zeta class
    33% identity, 85% coverage of query (69.7 bits)

2v6kA / O86043 Structure of maleyl pyruvate isomerase, a bacterial glutathione-s- transferase in zeta class, in complex with substrate analogue dicarboxyethyl glutathione (see paper)
    33% identity, 85% coverage of query (69.3 bits)

4zb6D / A0A0R4I980 Crystal structure of glutathione transferase ure2p4 from phanerochaete chrysosporium in complex with oxidized glutathione. (see paper)
    30% identity, 84% coverage of query (69.3 bits)

GSTF2_TOBAC / P46440 Glutathione S-transferase APIC; GST class-phi; EC 2.5.1.18 from Nicotiana tabacum (Common tobacco)
    27% identity, 90% coverage of query (69.3 bits)

6tk8AAA f122t variant from alopecurus myosuroides
    26% identity, 92% coverage of query (69.3 bits)

GSTF_HYOMU / P46423 Glutathione S-transferase; 25 kDa auxin-binding protein; GST class-phi; EC 2.5.1.18 from Hyoscyamus muticus (Egyptian henbane) (see paper)
    29% identity, 84% coverage of query (68.9 bits)

5f06A / U5GTL0 Crystal structure of glutathione transferase f7 from populus trichocarpa (see paper)
    27% identity, 92% coverage of query (68.9 bits)

7oboAAA Glutathione transferase
    26% identity, 92% coverage of query (68.9 bits)

6rivA Crystal structure of alopecurus myosuroides gstf
    26% identity, 92% coverage of query (68.9 bits)

4f0cA / I7B368 Crystal structure of the glutathione transferase ure2p5 from phanerochaete chrysosporium (see paper)
    26% identity, 97% coverage of query (68.6 bits)

1k0cC Ure2p in complex with s-p-nitrobenzylglutathione
    27% identity, 84% coverage of query (68.6 bits)

GST1A_ANOGA / O77462 Glutathione S-transferase 1, isoform A; AgGst1-alpha; Aggst1-3; GST class-theta; EC 2.5.1.18 from Anopheles gambiae (African malaria mosquito) (see paper)
    30% identity, 76% coverage of query (68.2 bits)

4zbaA / A0A0R4I985 Crystal structure of the glutathione transferase ure2p8 from phanerochaete chrysosporium with oxidized glutathione. (see paper)
    28% identity, 89% coverage of query (68.2 bits)

4zbbA Crystal structure of the glutathione transferase ure2p8 from phanerochaete chrysosporium complexed with glutathionyl-s- dinitrobenzene.
    28% identity, 89% coverage of query (68.2 bits)

GSTFA_ARATH / P42761 Glutathione S-transferase F10; AtGSTF10; AtGSTF4; GST class-phi member 10; Protein EARLY RESPONSE TO DEHYDRATION 13; EC 2.5.1.18 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
    25% identity, 85% coverage of query (67.8 bits)

6tahB 6tahB
    26% identity, 85% coverage of query (67.0 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory