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Searching for up to 100 curated homologs for Ac3H11_3592 FitnessBrowser__acidovorax_3H11:Ac3H11_3592 (263 a.a.)

Found high-coverage hits (≥70%) to 34 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

F9VNL6 glyceraldehyde dehydrogenase (FAD-containing) (subunit 2/3) (EC 1.2.99.8) from Sulfurisphaera tokodaii (see paper)
    37% identity, 99% coverage of query (169 bits)

DCMM_HYDPS / P19914 Carbon monoxide dehydrogenase medium chain; CO dehydrogenase subunit M; CO-DH M; EC 1.2.5.3 from Hydrogenophaga pseudoflava (Pseudomonas carboxydoflava) (see paper)
P19914 aerobic carbon monoxide dehydrogenase (subunit 2/3) (EC 1.2.5.3) from Hydrogenophaga pseudoflava (see 2 papers)
    37% identity, 97% coverage of query (156 bits)

1ffuC / P19914 Carbon monoxide dehydrogenase from hydrogenophaga pseudoflava which lacks the mo-pyranopterin moiety of the molybdenum cofactor (see paper)
    41% identity, 77% coverage of query (152 bits)

Q974U9 glyceraldehyde dehydrogenase (FAD-containing) (subunit 2/3) (EC 1.2.99.8) from Sulfurisphaera tokodaii (see paper)
    33% identity, 98% coverage of query (139 bits)

ndhA / Q59127 NdhA (EC 1.5.99.4) from Paenarthrobacter nicotinovorans (see 2 papers)
NDHM_PAENI / Q59127 Nicotine 6-hydroxylase medium subunit; Nicotine dehydrogenase medium subunit; Nicotine dehydrogenase subunit A; NDH A; EC 1.5.99.4 from Paenarthrobacter nicotinovorans (Arthrobacter nicotinovorans) (see 2 papers)
Q59127 nicotine dehydrogenase (EC 1.5.99.4) from Paenarthrobacter nicotinovorans (see 2 papers)
AAK64243.1 ndhM from Paenarthrobacter nicotinovorans (see paper)
    35% identity, 97% coverage of query (133 bits)

1n5wC / P19920 Crystal structure of the cu,mo-co dehydrogenase (codh); oxidized form (see paper)
    34% identity, 98% coverage of query (131 bits)

DCMM_AFIC5 / P19920 Carbon monoxide dehydrogenase medium chain; CO dehydrogenase subunit M; CO-DH M; EC 1.2.5.3 from Afipia carboxidovorans (strain ATCC 49405 / DSM 1227 / KCTC 32145 / OM5) (Oligotropha carboxidovorans) (see 3 papers)
P19920 aerobic carbon monoxide dehydrogenase (EC 1.2.5.3); anaerobic carbon-monoxide dehydrogenase (subunit 2/3) (EC 1.2.7.4) from Afipia carboxidovorans (see 3 papers)
    34% identity, 98% coverage of query (131 bits)

4zohB / Q974U9 Crystal structure of glyceraldehyde oxidoreductase (see paper)
    32% identity, 98% coverage of query (131 bits)

SSO2636 / Q97VI7 glycolaldehyde oxidoreductase medium subunit from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (see paper)
    33% identity, 100% coverage of query (130 bits)

cutB / Q4J6M6 aldehyde dehydrogenase β subunit (EC 1.2.99.8) from Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770) (see paper)
CUTB_SULAC / Q4J6M6 Glyceraldehyde dehydrogenase medium chain; Glyceraldehyde dehydrogenase subunit B; Glyceraldehyde dehydrogenase subunit beta; EC 1.2.99.8 from Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770) (see paper)
Q4J6M6 glyceraldehyde dehydrogenase (FAD-containing) (subunit 2/3) (EC 1.2.99.8) from Sulfolobus acidocaldarius (see paper)
    33% identity, 90% coverage of query (130 bits)

Build an alignment

Build an alignment for Ac3H11_3592 and 10 homologs with ≥ 30% identity

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Additional hits (identity < 30%)

CDHB_PSEU3 / D7REY4 Caffeine dehydrogenase subunit beta; Caffeine dehydrogenase medium subunit; EC 1.17.5.2 from Pseudomonas sp. (strain CBB1) (see paper)
    28% identity, 98% coverage of query (122 bits)

1t3qC / P72222 Crystal structure of quinoline 2-oxidoreductase from pseudomonas putida 86 (see paper)
    33% identity, 98% coverage of query (122 bits)

P72222 quinoline 2-oxidoreductase (subunit 3/3) (EC 1.3.99.17) from Pseudomonas putida (see paper)
    33% identity, 98% coverage of query (122 bits)

7dqxE / O87681 Crystal structure of xanthine dehydrogenase family protein
    31% identity, 99% coverage of query (121 bits)

kdhA / O87681 ketone dehydrogenase medium subunit (EC 1.5.99.14) from Paenarthrobacter nicotinovorans (see paper)
KDHA_PAENI / O87681 6-hydroxypseudooxynicotine dehydrogenase complex subunit alpha; Ketone dehydrogenase medium FAD subunit; EC 1.5.99.14 from Paenarthrobacter nicotinovorans (Arthrobacter nicotinovorans) (see paper)
AAK64248.1 kdhM from Paenarthrobacter nicotinovorans (see paper)
kdhM / CAC37486.2 ketone dehydrogenase medium subunit from Paenarthrobacter nicotinovorans (see paper)
    31% identity, 99% coverage of query (120 bits)

atcB / A0A127F985 1-testosterone hydratase/dehydrogenase β subunit (EC 1.17.99.11) from Steroidobacter denitrificans (see 2 papers)
A0A127F985 3-oxo-DELTA1-steroid hydratase/dehydrogenase (subunit 2/3) (EC 1.17.99.11) from Steroidobacter denitrificans (see paper)
    34% identity, 97% coverage of query (120 bits)

AO356_02560 Xanthine dehydrogenase (EC 1.17.1.4) from Pseudomonas fluorescens FW300-N2C3
    32% identity, 85% coverage of query (76.3 bits)

3hrdG / Q0QLF4 Crystal structure of nicotinate dehydrogenase (see paper)
    29% identity, 74% coverage of query (74.7 bits)

ndhF / Q0QLF4 nicotinate hydroxylase 33 kD subunit (EC 1.17.1.5) from Eubacterium barkeri (see paper)
NDFS_EUBBA / Q0QLF4 Nicotinate dehydrogenase FAD-subunit; NDH; Nicotinic acid hydroxylase FAD-subunit; NAH; EC 1.17.1.5 from Eubacterium barkeri (Clostridium barkeri) (see 3 papers)
    29% identity, 74% coverage of query (74.3 bits)

hbaD / G3XCQ8 4-hydroxybenzoyl-CoA reductase HbaD subunit (EC 1.1.7.1) from Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009) (see 7 papers)
    29% identity, 79% coverage of query (69.7 bits)

1jroA / O54050 Crystal structure of xanthine dehydrogenase from rhodobacter capsulatus (see paper)
    30% identity, 99% coverage of query (67.8 bits)

2w54A Crystal structure of xanthine dehydrogenase from rhodobacter capsulatus in complex with bound inhibitor pterin-6-aldehyde
    30% identity, 99% coverage of query (67.4 bits)

PS417_20885 Xanthine dehydrogenase (EC 1.17.1.4) from Pseudomonas simiae WCS417
    29% identity, 88% coverage of query (67.0 bits)

O54050 xanthine dehydrogenase (subunit 2/2) (EC 1.17.1.4); xanthine oxidase (EC 1.17.3.2) from Rhodobacter capsulatus (see 2 papers)
xdhA / CAA04469.1 xanthine dehydrogenase from Rhodobacter capsulatus (see paper)
    29% identity, 98% coverage of query (66.6 bits)

5g5gB / P77324 Escherichia coli periplasmic aldehyde oxidase (see paper)
    30% identity, 83% coverage of query (64.3 bits)

YagS / b0285 aldehyde dehydrogenase, FAD-binding subunit (EC 1.2.99.6) from Escherichia coli K-12 substr. MG1655 (see paper)
paoB / P77324 aldehyde dehydrogenase, FAD-binding Fe-S subunit (EC 1.2.99.6) from Escherichia coli (strain K12) (see 3 papers)
PAOB_ECOLI / P77324 Aldehyde oxidoreductase FAD-binding subunit PaoB; EC 1.2.99.6 from Escherichia coli (strain K12) (see 4 papers)
P77324 xanthine dehydrogenase (subunit 2/3) (EC 1.17.1.4) from Escherichia coli (see paper)
    30% identity, 83% coverage of query (64.3 bits)

5y6qB / Q84IX9 Crystal structure of an aldehyde oxidase from methylobacillus sp. Ky4400 (see paper)
    26% identity, 84% coverage of query (63.5 bits)

Dshi_2958 Xanthine dehydrogenase (EC 1.17.1.4) from Dinoroseobacter shibae DFL-12
    30% identity, 88% coverage of query (62.0 bits)

XdhB / b2867 putative xanthine dehydrogenase FAD-binding subunit XdhB (EC 1.17.1.4) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
xdhB / Q46800 putative xanthine dehydrogenase FAD-binding subunit XdhB (EC 1.17.1.4) from Escherichia coli (strain K12) (see 2 papers)
Q46800 xanthine dehydrogenase (subunit 1/2) (EC 1.17.1.4) from Escherichia coli (see paper)
    28% identity, 90% coverage of query (57.0 bits)

hcrB / Q5P3F4 4-hydroxybenzoyl-CoA reductase, β subunit (EC 1.1.7.1) from Aromatoleum aromaticum (strain EbN1) (see 3 papers)
    27% identity, 98% coverage of query (54.3 bits)

1rm6B / O33820 Structure of 4-hydroxybenzoyl-coa reductase from thauera aromatica (see paper)
    29% identity, 76% coverage of query (52.4 bits)

hcrB / O33820 4-hydroxybenzoyl-CoA reductase β subunit (EC 1.1.7.1) from Thauera aromatica (see paper)
HCRB_THAAR / O33820 4-hydroxybenzoyl-CoA reductase subunit beta; 4-HBCR subunit beta; EC 1.1.7.1 from Thauera aromatica (see 2 papers)
hcrB / CAA05039.1 4-Hydroxybenzoyl-CoA reductase beta-subunit from Thauera aromatica (see paper)
    29% identity, 76% coverage of query (52.4 bits)

YgfM / b2880 putative oxidoreductase from Escherichia coli K-12 substr. MG1655 (see paper)
    26% identity, 76% coverage of query (47.4 bits)

XDH1 / Q8GUQ8 xanthine dehydrogenase monomer (EC 1.17.1.4) from Arabidopsis thaliana (see paper)
XDH1_ARATH / Q8GUQ8 Xanthine dehydrogenase 1; AtXDH1; EC 1.17.1.4 from Arabidopsis thaliana (Mouse-ear cress) (see 6 papers)
    23% identity, 70% coverage of query (42.7 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory