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Searching for up to 100 curated homologs for Ac3H11_4183 FitnessBrowser__acidovorax_3H11:Ac3H11_4183 (272 a.a.)

Found high-coverage hits (≥70%) to 22 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

TC 3.A.1.11.3 / Q44381 MotD, component of Mannopine porter from Agrobacterium tumefaciens (see paper)
    38% identity, 88% coverage of query (168 bits)

TC 3.A.1.11.6 / Q1M7Q2 Putative spermidine/putrescine transport system ABC transporter permease component, component of The γ-aminobutyrate (GABA) uptake system, GtsABCD from Rhizobium leguminosarum bv. viciae (strain 3841) (see paper)
    36% identity, 86% coverage of query (167 bits)

PotC / b1124 spermidine preferential ABC transporter membrane subunit PotC (EC 7.6.2.11; EC 7.6.2.16) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
PotC / P0AFK6 spermidine preferential ABC transporter membrane subunit PotC (EC 7.6.2.11) from Escherichia coli (strain K12) (see 2 papers)
POTC_ECOLI / P0AFK6 Spermidine/putrescine transport system permease protein PotC from Escherichia coli (strain K12) (see paper)
TC 3.A.1.11.1 / P0AFK6 Spermidine/putrescine transport system permease protein PotC aka B1124, component of Polyamine (putrescine/spermidine) uptake porter from Escherichia coli (see 5 papers)
potC spermidine/putrescine ABC transporter, permease protein PotC from Escherichia coli K12 (see paper)
    31% identity, 82% coverage of query (113 bits)

TC 3.A.1.11.4 / O70071 ChtK, component of Chrysopine porter
    34% identity, 85% coverage of query (112 bits)

YdcV / b1443 putative ABC transporter membrane subunit YdcV from Escherichia coli K-12 substr. MG1655 (see 4 papers)
ydcV / P0AFR9 putative ABC transporter membrane subunit YdcV from Escherichia coli (strain K12) (see 4 papers)
YDCV_ECOLI / P0AFR9 Inner membrane ABC transporter permease protein YdcV from Escherichia coli (strain K12) (see 2 papers)
    36% identity, 87% coverage of query (105 bits)

PotI / b0857 putrescine ABC transporter membrane subunit PotI (EC 7.6.2.11; EC 7.6.2.16) from Escherichia coli K-12 substr. MG1655 (see 2 papers)
PotI / P0AFL1 putrescine ABC transporter membrane subunit PotI (EC 7.6.2.11) from Escherichia coli (strain K12) (see paper)
POTI_ECOLI / P0AFL1 Putrescine transport system permease protein PotI from Escherichia coli (strain K12) (see 3 papers)
TC 3.A.1.11.2 / P0AFL1 PotI aka B0857, component of Putrescine porter from Escherichia coli (see 5 papers)
    35% identity, 82% coverage of query (104 bits)

Build an alignment

Build an alignment for Ac3H11_4183 and 6 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

G7SFQ8 ABC-type polyamine transporter (subunit 2/4) (EC 7.6.2.11) from Streptococcus suis (see paper)
    28% identity, 89% coverage of query (97.1 bits)

TC 3.A.1.11.7 / Q97Q44 Spermidine/putrescine ABC transporter, permease protein, component of The spermidine/putrescine uptake porter, PotABCD from Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)
    24% identity, 88% coverage of query (88.6 bits)

TC 3.A.1.6.5 / Q8U4K4 WtpB, component of Tungsten (KM=20pM)/molybdate (KM=10nM) porter from Pyrococcus furiosus (see paper)
    26% identity, 82% coverage of query (75.5 bits)

TC 3.A.1.1.6 / Q48397 CymG, component of Cyclodextrin porter from Klebsiella oxytoca (see paper)
    30% identity, 72% coverage of query (69.3 bits)

smoH / Q7CS31 ABC-type 3-(6-sulfo-α-D-quinovosyl)-sn-glycerol transporter permease subunit from Agrobacterium fabrum (strain C58 / ATCC 33970) (see paper)
    26% identity, 71% coverage of query (68.6 bits)

TC 3.A.1.20.1 / O54371 BitE, component of The iron transporter, BitABCDEF from Treponema hyodysenteriae (Serpulina hyodysenteriae) (see paper)
    25% identity, 92% coverage of query (64.7 bits)

WTPB_ARCFU / O30143 Molybdate/tungstate transport system permease protein WtpB from Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16) (see paper)
TC 3.A.1.6.8 / O30143 Molybdate/tungstate transport system permease protein WtpB, component of Molybdate/tungstate transport system, ModABC (WtpABC) (ModA binds to ModBC with high affinity (0.11%u03BCM) and dissociates slowly; the complex is destabilized by nucleotide and substrate binding from Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)
    25% identity, 76% coverage of query (62.8 bits)

TC 3.A.1.20.1 / O54372 BitF, component of The iron transporter, BitABCDEF from Treponema hyodysenteriae (Serpulina hyodysenteriae) (see paper)
    25% identity, 80% coverage of query (62.8 bits)

TC 3.A.1.1.38 / Q9WYQ1 Sugar ABC transporter, permease protein, component of Inositol phosphate porter (Rodionova et al. 2013). Binds inositol phosphate with low Kd and inositol with a lower affinity from Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
    27% identity, 73% coverage of query (61.2 bits)

PGA1_c27950 N-Acetyl-D-glucosamine ABC transport system, permease component 2 from Phaeobacter inhibens BS107
    27% identity, 75% coverage of query (60.1 bits)

A0A0K2E5X6 ABC-type polyamine transporter (subunit 3/4) (EC 7.6.2.11) from Streptococcus suis (see paper)
    29% identity, 74% coverage of query (60.1 bits)

sugB / P9WG01 ABC-type trehalose transporter integral membrane protein from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 2 papers)
SUGB_MYCTU / P9WG01 Trehalose transport system permease protein SugB from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
TC 3.A.1.1.31 / O50453 PROBABLE SUGAR-TRANSPORT INTEGRAL MEMBRANE PROTEIN ABC TRANSPORTER SUGB, component of The trehalose-recycling ABC transporter, LpqY-SugA-SugB-SugC (essential for virulence) from Mycobacterium tuberculosis (see 3 papers)
    26% identity, 74% coverage of query (58.9 bits)

MALG_THELN / Q7LYX6 Trehalose/maltose transport system permease protein MalG from Thermococcus litoralis (strain ATCC 51850 / DSM 5473 / JCM 8560 / NS-C) (see 3 papers)
TC 3.A.1.1.7 / O51925 MalG aka PF1741, component of Maltose/trehalose porter (see paper)
    25% identity, 81% coverage of query (57.8 bits)

TC 3.A.1.11.3 / Q44382 MotC, component of Mannopine porter from Agrobacterium tumefaciens (see paper)
    25% identity, 92% coverage of query (57.8 bits)

TC 3.A.1.6.3 / P71745 CysT aka RV2399C aka MTCY253.22 aka MT2470, component of Sulfate porter from Mycobacterium tuberculosis (see 3 papers)
    29% identity, 72% coverage of query (57.4 bits)

TC 3.A.1.1.5 / O30833 SmoG, component of Hexitol (glucitol; mannitol) porter from Rhodobacter sphaeroides (Rhodopseudomonas sphaeroides) (see paper)
    28% identity, 74% coverage of query (55.5 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory