Searching for up to 100 curated homologs for Ac3H11_4666 Phosphoribosylglycinamide formyltransferase 2 (EC 2.1.2.-) (400 a.a.)
Found high-coverage hits (≥70%) to 37 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
purT / Q58881 phosphoribosylglycinamide formyltransferase monomer (EC 6.3.1.21) from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (see paper)
59% identity, 98% coverage of query (434 bits)
PurT / b1849 phosphoribosylglycinamide formyltransferase 2 (EC 2.7.2.15; EC 2.7.2.1) from Escherichia coli K-12 substr. MG1655 (see 10 papers)
purT / P33221 phosphoribosylglycinamide formyltransferase 2 (EC 6.3.1.21; EC 2.7.2.15) from Escherichia coli (strain K12) (see 8 papers)
PURT_ECOLI / P33221 Formate-dependent phosphoribosylglycinamide formyltransferase; 5'-phosphoribosylglycinamide transformylase 2; Formate-dependent GAR transformylase; GAR transformylase 2; GART 2; GAR transformylase T; Non-folate glycinamide ribonucleotide transformylase; Phosphoribosylglycinamide formyltransferase 2; EC 6.3.1.21 from Escherichia coli (strain K12) (see 6 papers)
P33221 phosphoribosylglycinamide formyltransferase 2 (EC 6.3.1.21) from Escherichia coli (see 5 papers)
59% identity, 99% coverage of query (426 bits)
1eyzA / P33221 Structure of escherichia coli purt-encoded glycinamide ribonucleotide transformylase complexed with mg and amppnp (see paper)
59% identity, 99% coverage of query (419 bits)
1kjiA Crystal structure of glycinamide ribonucleotide transformylase in complex with mg-amppcp
59% identity, 99% coverage of query (419 bits)
1ez1A Structure of escherichia coli purt-encoded glycinamide ribonucleotide transformylase complexed with mg, amppnp, and gar
59% identity, 99% coverage of query (419 bits)
E8X9F0 phosphoribosylglycinamide formyltransferase 2 (EC 6.3.1.21) from Salmonella enterica subsp. enterica serovar Typhimurium (see paper)
57% identity, 99% coverage of query (417 bits)
1kjjA Crystal structure of glycniamide ribonucleotide transformylase in complex with mg-atp-gamma-s
58% identity, 99% coverage of query (414 bits)
1kj8A Crystal structure of purt-encoded glycinamide ribonucleotide transformylase in complex with mg-atp and gar
58% identity, 99% coverage of query (414 bits)
1kjqA Crystal structure of glycinamide ribonucleotide transformylase in complex with mg-adp
58% identity, 99% coverage of query (412 bits)
O58056 Formate-dependent phosphoribosylglycinamide formyltransferase; 5'-phosphoribosylglycinamide transformylase 2; Formate-dependent GAR transformylase; GAR transformylase 2; GART 2; Non-folate glycinamide ribonucleotide transformylase; Phosphoribosylglycinamide formyltransferase 2; EC 6.3.1.21 from Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)
47% identity, 99% coverage of query (354 bits)
2dwcB / O58056 Crystal structure of probable phosphoribosylglycinamide formyl transferase from pyrococcus horikoshii ot3 complexed with adp
46% identity, 99% coverage of query (331 bits)
P95197 phosphoribosylglycinamide formyltransferase 2 (EC 6.3.1.21) from Mycobacterium tuberculosis (see paper)
40% identity, 98% coverage of query (258 bits)
Build an alignment for Ac3H11_4666 and 12 homologs with ≥ 30% identity
Or download the sequences
Q2QJL2 5-(carboxyamino)imidazole ribonucleotide mutase (EC 5.4.99.18) from Acetobacter aceti (see paper)
purK / AAZ04484.1 N5-carboxyaminoimidazole ribonucleotide synthetase from Acetobacter aceti (see paper)
29% identity, 93% coverage of query (133 bits)
3r5hA Crystal structure of adp-air complex of purk: n5-carboxyaminoimidazole ribonucleotide synthetase (see paper)
27% identity, 93% coverage of query (111 bits)
P15567 phosphoribosylaminoimidazole carboxylase (EC 4.1.1.21) from Schizosaccharomyces pombe (see paper)
ade6 / RF|NP_588141.1 phosphoribosylaminoimidazole carboxylase Ade6; EC 4.1.1.21 from Schizosaccharomyces pombe (see paper)
28% identity, 90% coverage of query (110 bits)
3v4sA Crystal structure of adp-atp complex of purk: n5-carboxyaminoimidazole ribonucleotide synthetase
27% identity, 93% coverage of query (110 bits)
3q2oB Crystal structure of purk: n5-carboxyaminoimidazole ribonucleotide synthetase
27% identity, 92% coverage of query (109 bits)
3v4sB Crystal structure of adp-atp complex of purk: n5-carboxyaminoimidazole ribonucleotide synthetase
27% identity, 92% coverage of query (109 bits)
4dlkA Crystal structure of atp-ca++ complex of purk: n5- carboxyaminoimidazole ribonucleotide synthetase
27% identity, 92% coverage of query (109 bits)
Q01930 phosphoribosylaminoimidazole carboxylase (EC 4.1.1.21) from Ogataea methanolica (see paper)
27% identity, 90% coverage of query (107 bits)
5jqwA The crystal structure of phosphoribosylaminoimidazole carboxylase atpase subunit of francisella tularensis subsp. Tularensis schu s4 in complex with adp
29% identity, 78% coverage of query (107 bits)
4ma0A The crystal structure of phosphoribosylaminoimidazole carboxylase atpase subunit of francisella tularensis subsp. Tularensis schu s4 in complex with partially hydrolysed atp
29% identity, 78% coverage of query (107 bits)
4mamA / Q5NGE8 The crystal structure of phosphoribosylaminoimidazole carboxylase atpase subunit of francisella tularensis subsp. Tularensis schu s4 in complex with an adp analog, amp-cp
29% identity, 78% coverage of query (106 bits)
Q9UVE6 phosphoribosylaminoimidazole carboxylase (EC 4.1.1.21) from Zygosaccharomyces rouxii (see paper)
27% identity, 91% coverage of query (105 bits)
ADE2 / AAA96380.1 phosphoribosylaminoimidazole carboxylase from Schwanniomyces occidentalis (see paper)
25% identity, 90% coverage of query (100 bits)
4ma5A The crystal structure of phosphoribosylaminoimidazole carboxylase atpase subunit of francisella tularensis subsp. Tularensis schu s4 in complex with an atp analog, amp-pnp.
29% identity, 78% coverage of query (98.6 bits)
ADE2 / P21264 phosphoribosylaminoimidazole carboxylase (EC 4.1.1.21) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see 3 papers)
PUR6_YEAST / P21264 Phosphoribosylaminoimidazole carboxylase; AIR carboxylase; AIRC; EC 4.1.1.21 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
P21264 phosphoribosylaminoimidazole carboxylase (EC 4.1.1.21) from Saccharomyces cerevisiae (see paper)
25% identity, 90% coverage of query (97.1 bits)
AN3626 phosphoribosyl-aminoimidazole carboxylase (AFU_orthologue; AFUA_4G12600) from Emericella nidulans (see paper)
26% identity, 85% coverage of query (90.5 bits)
3ax6A / Q9WYS8 Crystal structure of n5-carboxyaminoimidazole ribonucleotide synthetase from thermotoga maritima
26% identity, 91% coverage of query (90.1 bits)
3k5hA / A1CII2 Crystal structure of carboxyaminoimidazole ribonucleotide synthase from asperigillus clavatus complexed with atp (see paper)
25% identity, 85% coverage of query (86.7 bits)
A1CII2 5-(carboxyamino)imidazole ribonucleotide synthase (EC 6.3.4.18) from Aspergillus clavatus (see paper)
25% identity, 85% coverage of query (86.7 bits)
3k5iA Crystal structure of n5-carboxyaminoimidazole synthase from aspergillus clavatus in complex with adp and 5-aminoimadazole ribonucleotide
25% identity, 85% coverage of query (86.7 bits)
3aw8A / Q5SKY0 Crystal structure of n5-carboxyaminoimidazole ribonucleotide synthetase from thermus thermophilus hb8
30% identity, 73% coverage of query (86.3 bits)
Q92210 phosphoribosylaminoimidazole carboxylase (EC 4.1.1.21) from Candida albicans (see paper)
ADE2 phosphoribosylaminoimadazole carboxylase from Candida albicans (see 8 papers)
24% identity, 90% coverage of query (79.7 bits)
A0A0H3KFM7 5-(carboxyamino)imidazole ribonucleotide synthase (EC 6.3.4.18) from Staphylococcus aureus (see paper)
23% identity, 92% coverage of query (77.8 bits)
3orqA / A0A0H3KFM7 Crystal structure of n5-carboxyaminoimidazole synthetase from staphylococcus aureus complexed with adp (see paper)
23% identity, 92% coverage of query (77.8 bits)
PURK_MYCTU / P9WHL9 N5-carboxyaminoimidazole ribonucleotide synthase; N5-CAIR synthase; 5-(carboxyamino)imidazole ribonucleotide synthetase; EC 6.3.4.18 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
28% identity, 88% coverage of query (67.8 bits)
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Lawrence Berkeley National Laboratory