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Searching for up to 100 curated homologs for Ac3H11_4818 FitnessBrowser__acidovorax_3H11:Ac3H11_4818 (230 a.a.)

Found high-coverage hits (≥70%) to 19 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

SERCL_ARATH / F4KI56 Metal-independent phosphoserine phosphatase; iPSP; Phosphoglycerate mutase-like protein 3; EC 3.1.3.3 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
    33% identity, 91% coverage of query (105 bits)

YtjC / b4395 putative phosphatase from Escherichia coli K-12 substr. MG1655 (see 7 papers)
gpmB / RF|NP_418812 PGAM from Escherichia coli K12 (see paper)
    32% identity, 82% coverage of query (100 bits)

PSPB_HYDTT / D3DFP8 Putative phosphoserine phosphatase 2; PSP 2; PSPase 2; Metal-independent phosphoserine phosphatase 2; iPSP2; O-phosphoserine phosphohydrolase 2; EC 3.1.3.3 from Hydrogenobacter thermophilus (strain DSM 6534 / IAM 12695 / TK-6) (see paper)
D3DFP8 phosphoserine phosphatase (EC 3.1.3.3) from Hydrogenobacter thermophilus (see paper)
    31% identity, 84% coverage of query (89.0 bits)

Build an alignment

Build an alignment for Ac3H11_4818 and 3 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

PHOE_BACSU / O07617 Uncharacterized phosphatase PhoE; EC 3.1.3.- from Bacillus subtilis (strain 168) (see 2 papers)
    28% identity, 90% coverage of query (83.2 bits)

1h2eA / Q9ALU0 Bacillus stearothermophilus phoe (previously known as yhfr) in complex with phosphate (see paper)
    31% identity, 91% coverage of query (81.3 bits)

1h2fA Bacillus stearothermophilus phoe (previously known as yhfr) in complex with trivanadate
    31% identity, 91% coverage of query (81.3 bits)

YFFL_SCHPO / O94461 Probable phosphatase C1687.21; EC 3.1.3.- from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
    29% identity, 89% coverage of query (75.9 bits)

YO283_YEAST / Q12040 Broad-specificity phosphatase YOR283W; EC 3.1.3.- from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 4 papers)
    32% identity, 70% coverage of query (73.9 bits)

PSPA_HYDTT / D3DFG8 Phosphoserine phosphatase 1; PSP 1; PSPase 1; Metal-independent phosphoserine phosphatase 1; iPSP1; O-phosphoserine phosphohydrolase 1; EC 3.1.3.3 from Hydrogenobacter thermophilus (strain DSM 6534 / IAM 12695 / TK-6) (see paper)
D3DFG8 phosphoserine phosphatase (EC 3.1.3.3) from Hydrogenobacter thermophilus (see 3 papers)
    25% identity, 91% coverage of query (72.0 bits)

4ij6A / D3DFG8 Crystal structure of a novel-type phosphoserine phosphatase mutant (h9a) from hydrogenobacter thermophilus tk-6 in complex with l-phosphoserine (see paper)
    25% identity, 91% coverage of query (68.6 bits)

TIGAR_MOUSE / Q8BZA9 Fructose-2,6-bisphosphatase TIGAR; TP53-induced glycolysis and apoptosis regulator; TP53-induced glycolysis regulatory phosphatase; EC 3.1.3.46 from Mus musculus (Mouse) (see 4 papers)
Q8BZA9 fructose-2,6-bisphosphate 2-phosphatase (EC 3.1.3.46) from Mus musculus (see paper)
    32% identity, 74% coverage of query (68.2 bits)

PhpB / b0638 putative adenosylcobalamin phosphatase/α-ribazole phosphatase (EC 3.1.3.73) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
cobC / P52086 putative adenosylcobalamin phosphatase/α-ribazole phosphatase (EC 3.1.3.73) from Escherichia coli (strain K12) (see 2 papers)
    31% identity, 73% coverage of query (67.8 bits)

cobC / D1BMI5 adenosylcobamide phosphatase (EC 3.1.3.73) from Veillonella parvula (strain ATCC 10790 / DSM 2008 / CCUG 5123 / JCM 12972 / NCTC 11810 / Te3) (see paper)
    27% identity, 83% coverage of query (66.2 bits)

SHB17_YEAST / P36136 Sedoheptulose 1,7-bisphosphatase; EC 3.1.3.37 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 4 papers)
P36136 fructose-bisphosphatase (EC 3.1.3.11) from Saccharomyces cerevisiae (see paper)
    25% identity, 90% coverage of query (65.1 bits)

3lg2A / P36136 A ykr043c/ fructose-1,6-bisphosphate product complex following ligand soaking (see paper)
    25% identity, 90% coverage of query (65.1 bits)

3oi7A Structure of the structure of the h13a mutant of ykr043c in complex with sedoheptulose-1,7-bisphosphate
    25% identity, 90% coverage of query (61.2 bits)

3ll4A Structure of the h13a mutant of ykr043c in complex with fructose-1,6- bisphosphate
    25% identity, 90% coverage of query (61.2 bits)

CA1P_WHEAT / W5EP13 2-carboxy-D-arabinitol-1-phosphatase; EC 3.1.3.63 from Triticum aestivum (Wheat) (see paper)
    28% identity, 79% coverage of query (60.8 bits)

CA1P_ARATH / Q9FNJ9 Probable 2-carboxy-D-arabinitol-1-phosphatase; EC 3.1.3.63 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
    27% identity, 82% coverage of query (60.1 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory