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Searching for up to 100 curated homologs for Ac3H11_517 FitnessBrowser__acidovorax_3H11:Ac3H11_517 (552 a.a.)

Found high-coverage hits (≥70%) to 16 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

B0V8W9 NAD+ synthase (glutamine-hydrolysing) (EC 6.3.5.1) from Acinetobacter baumannii (see paper)
    46% identity, 100% coverage of query (491 bits)

NADE_ACIAD / Q6F8K4 Glutamine-dependent NAD(+) synthetase; NAD synthetase; NAD(+) synthase [glutamine-hydrolyzing]; EC 6.3.5.1 from Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1) (see paper)
    47% identity, 100% coverage of query (485 bits)

5khaA / V5VHL3 Structure of glutamine-dependent NAD+ synthetase from acinetobacter baumannii in complex with adenosine diphosphate (adp)
    43% identity, 100% coverage of query (450 bits)

NADE_RHOCA / Q03638 Glutamine-dependent NAD(+) synthetase; NAD(+) synthase [glutamine-hydrolyzing]; EC 6.3.5.1 from Rhodobacter capsulatus (Rhodopseudomonas capsulata) (see paper)
nadE / GB|CAA42042.1 NAD(+) synthase (glutamine-hydrolyzing); EC 6.3.5.1 from Rhodobacter capsulatus (see 2 papers)
    48% identity, 99% coverage of query (443 bits)

Build an alignment

Build an alignment for Ac3H11_517 and 4 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

D8IS59 NAD+ synthase (glutamine-hydrolysing) (EC 6.3.5.1) from Herbaspirillum seropedicae (see paper)
    27% identity, 85% coverage of query (143 bits)

NADE_MYCTU / P9WJJ3 Glutamine-dependent NAD(+) synthetase; NAD(+) synthase [glutamine-hydrolyzing]; EC 6.3.5.1 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 4 papers)
P9WJJ3 NAD+ synthase (glutamine-hydrolysing) (EC 6.3.5.1) from Mycobacterium tuberculosis (see paper)
nadE NAD(+) synthase (glutamine-hydrolyzing); EC 6.3.5.1 from Mycobacterium tuberculosis (see 3 papers)
    23% identity, 98% coverage of query (120 bits)

3dlaA X-ray crystal structure of glutamine-dependent NAD+ synthetase from mycobacterium tuberculosis bound to naad+ and don
    24% identity, 98% coverage of query (117 bits)

6ofcB / P9WJJ3 Crystal structure of m. Tuberculosis glutamine-dependent NAD+ synthetase complexed with sulfonamide derivative 1, pyrophosphate, and glutamine (see paper)
    23% identity, 98% coverage of query (114 bits)

3sytA Crystal structure of glutamine-dependent NAD+ synthetase from m. Tuberculosis bound to amp/ppi, NAD+, and glutamate
    24% identity, 98% coverage of query (114 bits)

3sezA Crystal structure of c176a mutant of glutamine-dependent NAD+ synthetase from m. Tuberculosis in complex with atp and naad+
    24% identity, 98% coverage of query (112 bits)

6ofcC Crystal structure of m. Tuberculosis glutamine-dependent NAD+ synthetase complexed with sulfonamide derivative 1, pyrophosphate, and glutamine
    23% identity, 98% coverage of query (111 bits)

3sytD Crystal structure of glutamine-dependent NAD+ synthetase from m. Tuberculosis bound to amp/ppi, NAD+, and glutamate
    24% identity, 98% coverage of query (111 bits)

3dlaB X-ray crystal structure of glutamine-dependent NAD+ synthetase from mycobacterium tuberculosis bound to naad+ and don
    23% identity, 98% coverage of query (110 bits)

3seqA Crystal structure of c176a mutant of glutamine-dependent NAD+ synthetase from m. Tuberculosis in complex with ampcpp and naad+
    23% identity, 98% coverage of query (110 bits)

3seqD / P9WJJ3 Crystal structure of c176a mutant of glutamine-dependent NAD+ synthetase from m. Tuberculosis in complex with ampcpp and naad+ (see paper)
    24% identity, 98% coverage of query (107 bits)

3sezC Crystal structure of c176a mutant of glutamine-dependent NAD+ synthetase from m. Tuberculosis in complex with atp and naad+
    24% identity, 98% coverage of query (106 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory