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Searching for up to 100 curated homologs for Ac3H11_545 FitnessBrowser__acidovorax_3H11:Ac3H11_545 (225 a.a.)

Found high-coverage hits (≥70%) to 25 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

pcaH2 / Q93PS2 protocatechuate 3,4-dioxygenase type II β subunit (EC 1.13.11.3) from Hydrogenophaga intermedia (see 4 papers)
    34% identity, 75% coverage of query (81.3 bits)

tcpC / Q471I0 6-chlorohydroxyquinol-1,2-dioxygenase from Cupriavidus pinatubonensis (strain JMP 134 / LMG 1197) (see 2 papers)
TCPC_CUPPJ / Q471I0 6-chlorohydroxyquinol 1,2-dioxygenase; 6-CHQ 1,2-dioxygenase; EC 1.13.11.- from Cupriavidus pinatubonensis (strain JMP 134 / LMG 1197) (Cupriavidus necator (strain JMP 134)) (see 3 papers)
    32% identity, 88% coverage of query (79.7 bits)

AO353_23525 Catechol 1,2-dioxygenase (EC 1.13.11.1) from Pseudomonas fluorescens FW300-N2E3
    33% identity, 79% coverage of query (73.2 bits)

catA-II / BAD11154.1 catechol 1,2-dioxygenase from Arthrobacter sp. BA-5-17 (see paper)
    33% identity, 72% coverage of query (72.4 bits)

catA / A0F0B5 catechol-1,2-dioxygenase (EC 1.13.11.1) from Pseudomonas reinekei (see paper)
A0F0B5 catechol 1,2-dioxygenase (EC 1.13.11.1) from Pseudomonas reinekei (see paper)
    33% identity, 73% coverage of query (72.0 bits)

catAI / BAA75207.1 catechol 1,2-dioxygenase from Frateuria sp. ANA-18 (see paper)
catA1 / BAC82534.1 catechol 1,2-dioxygenase from Frateuria sp. ANA-18 (see 3 papers)
    30% identity, 77% coverage of query (72.0 bits)

catA1 catechol 1,2-dioxygenase 1; EC 1.13.11.1 from Acinetobacter lwoffii (see 2 papers)
    30% identity, 77% coverage of query (71.6 bits)

5vxtB / B1Z4S0 Crystal structure of catechol 1,2-dioxygenase from burkholderia ambifaria
    30% identity, 72% coverage of query (70.5 bits)

PfGW456L13_3822 Catechol 1,2-dioxygenase (EC 1.13.11.1) from Pseudomonas fluorescens GW456-L13
    31% identity, 73% coverage of query (70.1 bits)

CATA_ACIAD / P07773 Catechol 1,2-dioxygenase; 1,2-CTD; EC 1.13.11.1 from Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1) (see paper)
P07773 catechol 1,2-dioxygenase (EC 1.13.11.1) from Acinetobacter baylyi ADP1 (see paper)
catA / AAC46426.1 catechol 1,2-dioxygenase from Acinetobacter baylyi (see 8 papers)
    30% identity, 79% coverage of query (68.9 bits)

5td3A Crystal structure of catechol 1,2-dioxygenase from burkholderia vietnamiensis
    30% identity, 72% coverage of query (68.9 bits)

1dlmA / P07773 Structure of catechol 1,2-dioxygenase from acinetobacter calcoaceticus native data (see paper)
    30% identity, 79% coverage of query (68.6 bits)

1dmhA Structure of catechol 1,2-dioxygenase from acinetobacter sp. Adp1 with bound 4-methylcatechol
    30% identity, 79% coverage of query (68.6 bits)

1dltA Structure of catechol 1,2-dioxygenase from acinetobacter sp. Adp1 with bound catechol
    30% identity, 79% coverage of query (68.6 bits)

catA2 / BAA75211.1 catechol 1,2-dioxygenase from Frateuria sp. ANA-18 (see paper)
    30% identity, 75% coverage of query (66.2 bits)

catA / BAA11859.1 catechol 1,2-dioxgenase from Rhodococcus erythropolis (see paper)
    31% identity, 78% coverage of query (65.9 bits)

catA2 / BAE46387.1 catechol 1,2-dioxygenase from Rhodococcus sp. AN-22 (see paper)
    30% identity, 73% coverage of query (65.9 bits)

Build an alignment

Build an alignment for Ac3H11_545 and 17 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

Q8GAZ6 catechol 1,2-dioxygenase (EC 1.13.11.1) from Burkholderia sp. (see paper)
    29% identity, 75% coverage of query (65.5 bits)

A0A193DXA9 protocatechuate 3,4-dioxygenase (subunit 2/2) (EC 1.13.11.3) from Rhizobium sp. LMB-1 (see paper)
    31% identity, 78% coverage of query (61.6 bits)

pcaG / AAF34267.1 protocatechuate 3,4-dioxygenase alpha chain from Agrobacterium tumefaciens (see 2 papers)
    31% identity, 78% coverage of query (58.2 bits)

tftH / Q45076 hydroxyquinol 1,2-dioxygenase monomer (EC 1.13.11.37) from Burkholderia cepacia (see paper)
    29% identity, 72% coverage of query (58.2 bits)

PRCA_EMENI / Q5AT14 Intradiol ring-cleavage dioxygenase prcA; Protocatechuate 3,4-dioxygenase A; EC 1.13.11.3 from Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) (see paper)
    26% identity, 78% coverage of query (57.8 bits)

PRCA_ASPNC / A2R1P9 Intradiol ring-cleavage dioxygenase prcA; Protocatechuate 3,4-dioxygenase A; EC 1.13.11.3 from Aspergillus niger (strain ATCC MYA-4892 / CBS 513.88 / FGSC A1513)
    24% identity, 78% coverage of query (55.8 bits)

Q9F103 catechol 1,2-dioxygenase (EC 1.13.11.1) from Acinetobacter radioresistens (see 2 papers)
    26% identity, 74% coverage of query (53.9 bits)

2xsrA / Q9F103 Crystal structure of wild type acinetobacter radioresistens catechol 1,2 dioxygenase (see paper)
    26% identity, 74% coverage of query (53.9 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory