Searching for up to 100 curated homologs for Ac3H11_552 FitnessBrowser__acidovorax_3H11:Ac3H11_552 (384 a.a.)

Found high-coverage hits (≥70%) to 23 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

Ac3H11_2396 ABC transporter for glutamine/isoleucine/leucine/phenylalanine/proline/serine/tyrosine, substrate-binding component from Acidovorax sp. GW101-3H11
    68% identity, 91% coverage of query (510 bits)

HSERO_RS00870 L-proline ABC transporter, substrate-binding component from Herbaspirillum seropedicae SmR1
    47% identity, 97% coverage of query (323 bits)

AZOBR_RS08260 L-proline and D-alanine ABC transporter, substrate-binding component from Azospirillum brasilense Sp245
    35% identity, 90% coverage of query (181 bits)

Pf6N2E2_2921 ABC transporter for L-leucine/L-phenylalanine/D-alanine, substrate-binding component LivK from Pseudomonas fluorescens FW300-N2E2
    33% identity, 95% coverage of query (168 bits)

BRAC_PSEAE / P21175 Leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein; LIVAT-BP; Leu/Ile/Val/Thr/Ala-binding protein from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see 2 papers)
TC 3.A.1.4.8 / P21175 Leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein, component of Branched chain amino acid uptake transporter. Transports alanine from Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
    32% identity, 97% coverage of query (166 bits)

AABP_PSEAE / Q9HUQ0 Amino acid binding protein from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
    32% identity, 96% coverage of query (154 bits)

TC 3.A.1.4.3 / Q9L3M3 BraC, component of General L- (and D-)amino acid uptake porter (transports acidic, basic, polar, semipolar and hydrophobic amino acids). The amino and carboxyl groups do not need to be α since γ-aminobutyric acid (GABA) is a substrate. The system may function with additional binding proteins since L-alanine uptake is not dependent on BraC from Rhizobium leguminosarum (biovar viciae) (see 2 papers)
braC / CAB75553.1 periplasmic binding protein from Rhizobium leguminosarum bv. viciae (see 2 papers)
    33% identity, 95% coverage of query (154 bits)

3ip5A / Q7CX36 Structure of atu2422-gaba receptor in complex with alanine (see paper)
    34% identity, 90% coverage of query (152 bits)

3ip9A Structure of atu2422-gaba receptor in complex with gaba
    34% identity, 90% coverage of query (152 bits)

3ip7A Structure of atu2422-gaba receptor in complex with valine
    34% identity, 90% coverage of query (152 bits)

3ip6A Structure of atu2422-gaba receptor in complex with proline
    34% identity, 90% coverage of query (152 bits)

3ipcA Structure of atu2422-gaba f77a mutant receptor in complex with leucine
    34% identity, 90% coverage of query (150 bits)

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Build an alignment for Ac3H11_552 and 12 homologs with ≥ 30% identity

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Additional hits (identity < 30%)

LIVB3_RHIJ3 / Q1MDE9 Leu/Ile/Val-binding protein BraC3 from Rhizobium johnstonii (strain DSM 114642 / LMG 32736 / 3841) (Rhizobium leguminosarum bv. viciae) (see paper)
    29% identity, 91% coverage of query (136 bits)

HrbC / b3458 L-leucine/L-phenylalanine ABC transporter periplasmic binding protein (EC 7.4.2.2) from Escherichia coli K-12 substr. MG1655 (see 17 papers)
livK / P04816 L-leucine/L-phenylalanine ABC transporter periplasmic binding protein (EC 7.4.2.2) from Escherichia coli (strain K12) (see 16 papers)
TC 3.A.1.4.1 / P04816 Livk aka B3458, component of Leucine; leucine/isoleucine/valine porter from Escherichia coli (see 9 papers)
livK leucine-specific-binding protein LivK from Escherichia coli K12 (see 9 papers)
    31% identity, 95% coverage of query (134 bits)

1usiA / P04816 L-leucine-binding protein with phenylalanine bound (see paper)
    31% identity, 86% coverage of query (132 bits)

1uskA L-leucine-binding protein with leucine bound
    31% identity, 86% coverage of query (132 bits)

4n0qB / Q8YEE8 Crystal structure of an abc transporter, substrate-binding protein from brucella melitensis 16m in complex with l-leucine using a crystal grown in a crystal former (microlytic)
    26% identity, 91% coverage of query (121 bits)

4q6wA / Q7VS30 Crystal structure of periplasmic binding protein type 1 from bordetella pertussis tohama i complexed with 3-hydroxy benzoic acid
    27% identity, 91% coverage of query (89.4 bits)

TC 3.A.1.4.10 / Q8DQI1 ABC transporter substrate-binding protein-branched chain amino acid transport, component of The branched chain hydrophobic amino acid transporter, LivJFGHM from Streptococcus pneumoniae (strain ATCC BAA-255 / R6)
    31% identity, 86% coverage of query (89.0 bits)

4gnrA / J9PBT7 1.0 angstrom resolution crystal structure of the branched-chain amino acid transporter substrate binding protein livj from streptococcus pneumoniae str. Canada mdr_19a in complex with isoleucine
    31% identity, 86% coverage of query (88.6 bits)

4q6bA Crystal structure of abc transporter substrate-binding protein fromdesulfitobacterium hafniense complex with leu
    25% identity, 84% coverage of query (82.4 bits)

3td9A / Q9X0L9 Crystal structure of a leucine binding protein livk (tm1135) from thermotoga maritima msb8 at 1.90 a resolution
    26% identity, 90% coverage of query (82.0 bits)

GLR35_ARATH / Q9SW97 Glutamate receptor 3.5; Ionotropic glutamate receptor GLR6; Ligand-gated ion channel 3.5 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
    22% identity, 86% coverage of query (47.4 bits)

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