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Searching for up to 100 curated homologs for BPHYT_RS01855 FitnessBrowser__BFirm:BPHYT_RS01855 (368 a.a.)

Found high-coverage hits (≥70%) to 10 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

L2HDH_ACHAE / A0A0M7LBC1 L-2-hydroxyglutarate dehydrogenase; EC 1.1.99.2 from Achromobacter aegrifaciens (see paper)
    66% identity, 98% coverage of query (479 bits)

3dmeA / Q7VU70 Crystal structure of conserved exported protein from bordetella pertussis. Northeast structural genomics target ber141
    64% identity, 98% coverage of query (468 bits)

L2HDH_ACCRE / A0A011QK89 L-2-hydroxyglutarate dehydrogenase; EC 1.1.99.2 from Accumulibacter regalis (see paper)
    57% identity, 96% coverage of query (408 bits)

L2HDH_ARATH / Q9LES4 L-2-hydroxyglutarate dehydrogenase, mitochondrial; EC 1.1.99.2 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
    48% identity, 98% coverage of query (379 bits)

8w7fB / Q9VJ28 Structure of drosophila melanogaster l-2-hydroxyglutarate dehydrogenase bound with fad and a sulfate ion (see paper)
    30% identity, 94% coverage of query (132 bits)

8w78A Structure of drosophila melanogaster l-2-hydroxyglutarate dehydrogenase in complex with fad and 2-oxoglutarate
    30% identity, 94% coverage of query (129 bits)

Build an alignment

Build an alignment for BPHYT_RS01855 and 6 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

GLPDH_CALMK / A0A0R3K2G2 Glycerol 3-phosphate dehydrogenase; EC 1.1.99.- from Caloramator mitchellensis (see paper)
    27% identity, 98% coverage of query (125 bits)

LHGD_SALHO / A0A5Y6MCT2 L-2-hydroxyglutarate dehydrogenase; L2HG dehydrogenase; L2HG:quinone oxidoreductase; EC 1.1.5.13 from Salmonella houtenae (see paper)
    28% identity, 82% coverage of query (112 bits)

lhgO / Q88IT9 (S)-2-hydroxyglutarate oxidase from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440) (see 2 papers)
    25% identity, 92% coverage of query (100 bits)

Q70GP9 glycerol-3-phosphate oxidase (EC 1.1.3.21) from Mycoplasma mycoides subsp. mycoides (see paper)
glpO glycerol-3-phosphate oxidase; EC 1.1.3.21 from Mycoplasma mycoides subsp. mycoides SC (see paper)
    26% identity, 96% coverage of query (75.5 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory