Searching for up to 100 curated homologs for BPHYT_RS02050 FitnessBrowser__BFirm:BPHYT_RS02050 (427 a.a.)
Found high-coverage hits (≥70%) to 45 curated proteins.
Removed hits that are identical to the query, leaving 44
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
Ac3H11_2078 D-mannose isomerase (EC 5.3.1.7) from Acidovorax sp. GW101-3H11
57% identity, 93% coverage of query (462 bits)
MANI_MARM1 / F2JVT6 D-mannose isomerase; MI; EC 5.3.1.7 from Marinomonas mediterranea (strain ATCC 700492 / JCM 21426 / NBRC 103028 / MMB-1) (see paper)
56% identity, 91% coverage of query (443 bits)
Sama_0560 D-mannose isomerase (EC 5.3.1.7) from Shewanella amazonensis SB2B
51% identity, 91% coverage of query (392 bits)
HSERO_RS03650 Mannose isomerase (EC 5.3.1.7) from Herbaspirillum seropedicae SmR1
50% identity, 92% coverage of query (353 bits)
AO353_03400 D-mannose isomerase (EC 5.3.1.7) from Pseudomonas fluorescens FW300-N2E3
33% identity, 79% coverage of query (161 bits)
MANI_THEFU / A0A077LPS9 D-mannose isomerase; EC 5.3.1.7 from Thermobifida fusca (Thermomonospora fusca)
35% identity, 77% coverage of query (158 bits)
SQUS_SALTY / Q8ZKT7 Sulfoquinovose isomerase; SQ isomerase; Sulfoquinovose-sulfofructose isomerase; SQ-SF isomerase; EC 5.3.1.31 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 2 papers)
30% identity, 92% coverage of query (152 bits)
PGA1_c16670 D-mannose isomerase (EC 5.3.1.7) from Phaeobacter inhibens BS107
32% identity, 93% coverage of query (150 bits)
Build an alignment for BPHYT_RS02050 and 8 homologs with ≥ 30% identity
Or download the sequences
SquS / b3880 sulfoquinovose isomerase (EC 5.3.1.31; EC 5.3.1.7) from Escherichia coli K-12 substr. MG1655 (see 8 papers)
yihS / P32140 sulfoquinovose isomerase (EC 5.3.1.31; EC 5.3.1.7) from Escherichia coli (strain K12) (see 6 papers)
SQUS_ECOLI / P32140 Sulfoquinovose isomerase; SQ isomerase; Sulfoquinovose-sulfofructose isomerase; SQ-SF isomerase; EC 5.3.1.31 from Escherichia coli (strain K12) (see 3 papers)
yihS / RF|NP_418316 uncharacterized sugar isomerase yihS from Escherichia coli K12 (see paper)
29% identity, 92% coverage of query (150 bits)
7ag4D / Q8ZKT7 Crystal structure of active site mutant of sq isomerase (yihs-h248a) from salmonella enterica in complex with sulfofructose (sf) (see paper)
29% identity, 92% coverage of query (148 bits)
2zblA Functional annotation of salmonella enterica yihs-encoded protein
29% identity, 92% coverage of query (148 bits)
Pf1N1B4_597 D-mannose isomerase (EC 5.3.1.7) from Pseudomonas fluorescens FW300-N1B4
33% identity, 88% coverage of query (146 bits)
PS417_22150 D-mannose isomerase (EC 5.3.1.7) from Pseudomonas simiae WCS417
33% identity, 85% coverage of query (144 bits)
MANI_PSEC1 / A0A0P9JFY5 D-mannose isomerase; PsMIaseA; EC 5.3.1.7 from Pseudomonas cannabina pv. alisalensis (strain ATCC BAA-566 / CFBP 6866 / ICMP 15200 / BS91) (see paper)
32% identity, 86% coverage of query (135 bits)
AO356_05200 D-mannose isomerase (EC 5.3.1.7) from Pseudomonas fluorescens FW300-N2C3
33% identity, 75% coverage of query (130 bits)
3wkgA / F8WRK9 Crystal structure of cellobiose 2-epimerase in complex with glucosylmannose (see paper)
26% identity, 88% coverage of query (97.1 bits)
CEEP_RHOMR / F8WRK9 Cellobiose 2-epimerase; CE; EC 5.1.3.11 from Rhodothermus marinus (Rhodothermus obamensis) (see paper)
F8WRK9 cellobiose epimerase (EC 5.1.3.11) from Rhodothermus marinus (see 5 papers)
26% identity, 88% coverage of query (97.1 bits)
3wkhA Crystal structure of cellobiose 2-epimerase in complex with epilactose
26% identity, 88% coverage of query (97.1 bits)
3wkiA Crystal structure of cellobiose 2-epimerase in complex with cellobiitol
26% identity, 88% coverage of query (97.1 bits)
8h1lB / A0A7U4E834 Crystal structure of glucose-2-epimerase in complex with d-glucitol from runella slithyformis runsl_4512 (see paper)
24% identity, 88% coverage of query (95.5 bits)
A9AYF3 cellobiose epimerase (EC 5.1.3.11) from Herpetosiphon aurantiacus (see paper)
25% identity, 90% coverage of query (92.0 bits)
D0MF61 cellobiose epimerase (EC 5.1.3.11) from Rhodothermus marinus (see paper)
26% identity, 88% coverage of query (91.7 bits)
Q3M763 N-acylglucosamine 2-epimerase (EC 5.1.3.8) from Trichormus variabilis (see 2 papers)
25% identity, 88% coverage of query (88.6 bits)
Dfer_5652 / C6VWU2 mannose 2-epimerase monomer (EC 5.1.3.44) from Dyadobacter fermentans (strain ATCC 700827 / DSM 18053 / CIP 107007 / KCTC 52180 / NS114) (see paper)
C6VWU2 mannose 2-epimerase (EC 5.1.3.44) from Runella slithyformis (see paper)
24% identity, 92% coverage of query (87.0 bits)
G0GBL0 cellobiose epimerase (EC 5.1.3.11) from Spirochaeta thermophila (see paper)
28% identity, 80% coverage of query (83.2 bits)
E0RU15 cellobiose epimerase (EC 5.1.3.11) from Spirochaeta thermophila (see 2 papers)
29% identity, 80% coverage of query (80.5 bits)
D2QDA5 cellobiose epimerase (EC 5.1.3.11) from Spirosoma linguale (see paper)
22% identity, 88% coverage of query (72.4 bits)
A0A0A1HAT7 cellobiose epimerase (EC 5.1.3.11) from uncultured bacterium (see paper)
22% identity, 89% coverage of query (70.1 bits)
A5FA14 cellobiose epimerase (EC 5.1.3.11) from Flavobacterium johnsoniae (see 2 papers)
20% identity, 92% coverage of query (69.7 bits)
A7LVG6 N-acylglucosamine 2-epimerase (EC 5.1.3.8) from Bacteroides ovatus (see paper)
22% identity, 78% coverage of query (68.2 bits)
F5ITJ6 cellobiose epimerase (EC 5.1.3.11) from Dysgonomonas gadei (see paper)
21% identity, 89% coverage of query (65.9 bits)
C6VW66 cellobiose epimerase (EC 5.1.3.11) from Dyadobacter fermentans (see 2 papers)
21% identity, 85% coverage of query (65.1 bits)
CEEP_EUBCE / B3XZI5 Cellobiose 2-epimerase; CE; EC 5.1.3.11 from Eubacterium cellulosolvens (see paper)
B3XZI5 cellobiose epimerase (EC 5.1.3.11) from [Eubacterium] cellulosolvens (see 2 papers)
24% identity, 87% coverage of query (60.8 bits)
ce-ne1 / P0DKY4 lactose 2-epimerase (EC 5.1.3.11) from Ruminococcus albus (see 5 papers)
CEEP_RUMAL / P0DKY4 Cellobiose 2-epimerase; CE; EC 5.1.3.11 from Ruminococcus albus (see 2 papers)
P0DKY4 cellobiose epimerase (EC 5.1.3.11) from Ruminococcus albus (see 5 papers)
21% identity, 86% coverage of query (59.7 bits)
SMc03111 mannose 6-phosphate isomerase (EC 5.3.1.8) from Sinorhizobium meliloti 1021
PMI / AAA26356.1 phosphomannose isomerase from Sinorhizobium meliloti (see paper)
26% identity, 85% coverage of query (59.3 bits)
C6XVU9 cellobiose epimerase (EC 5.1.3.11) from Pedobacter heparinus (see 2 papers)
22% identity, 84% coverage of query (57.8 bits)
bfce / Q5LH66 cellobiose 2-epimerase (EC 5.1.3.11) from Bacteroides fragilis (strain ATCC 25285 / DSM 2151 / CCUG 4856 / JCM 11019 / NCTC 9343 / Onslow) (see 3 papers)
CEEP_BACFN / Q5LH66 Cellobiose 2-epimerase; CE; Mannobiose 2-epimerase; MBE; EC 5.1.3.11 from Bacteroides fragilis (strain ATCC 25285 / DSM 2151 / CCUG 4856 / JCM 11019 / NCTC 9343 / Onslow) (see 2 papers)
Q5LH66 cellobiose epimerase (EC 5.1.3.11) from Bacteroides fragilis (see 3 papers)
23% identity, 86% coverage of query (55.8 bits)
A4XGA6 cellobiose epimerase (EC 5.1.3.11) from Caldicellulosiruptor saccharolyticus (see 7 papers)
21% identity, 91% coverage of query (53.1 bits)
7d5gA Crystal structure of the csce with ligand to have a insight into the catalytic mechanism
21% identity, 91% coverage of query (53.1 bits)
8wbuA / A4XGA6 The crystal structure of circular mannose with mutant h247f of the cellobiose 2-epimerase from caldicellulosiruptor saccharolyticus
21% identity, 91% coverage of query (52.4 bits)
8wbvA The crystal structure of linear mannose with mutant h247f of the cellobiose 2-epimerase from caldicellulosiruptor saccharolyticus
21% identity, 91% coverage of query (52.4 bits)
RENBP_RAT / P51607 N-acylglucosamine 2-epimerase; AGE; GlcNAc 2-epimerase; N-acetyl-D-glucosamine 2-epimerase; Renin-binding protein; RnBP; EC 5.1.3.8 from Rattus norvegicus (Rat) (see 2 papers)
23% identity, 89% coverage of query (50.4 bits)
R7AVK7 cellobiose epimerase (EC 5.1.3.11) from Firmicutes bacterium (see paper)
21% identity, 81% coverage of query (50.1 bits)
RENBP_MOUSE / P82343 N-acylglucosamine 2-epimerase; AGE; GlcNAc 2-epimerase; N-acetyl-D-glucosamine 2-epimerase; Renin-binding protein; RnBP; EC 5.1.3.8 from Mus musculus (Mouse) (see paper)
22% identity, 85% coverage of query (48.5 bits)
Or start over
Lawrence Berkeley National Laboratory