Searching for up to 100 curated homologs for BPHYT_RS02460 FitnessBrowser__BFirm:BPHYT_RS02460 (265 a.a.)
Found high-coverage hits (≥70%) to 100 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
TC 3.A.1.17.4 / Q2BM69 Putative taurin uptake ABC transporter ATP-binding protein, component of The taurine uptake system, TauABC from Neptuniibacter caesariensis
55% identity, 98% coverage of query (306 bits)
Q6RH47 taurine dehydrogenase (EC 1.4.99.2) from Paracoccus pantotrophus (see paper)
58% identity, 95% coverage of query (302 bits)
TauB / b0366 taurine ABC transporter ATP binding subunit (EC 7.6.2.7) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
TauB / Q47538 taurine ABC transporter ATP binding subunit (EC 7.6.2.7) from Escherichia coli (strain K12) (see 3 papers)
TAUB_ECOLI / Q47538 Taurine import ATP-binding protein TauB; EC 7.6.2.7 from Escherichia coli (strain K12) (see 2 papers)
TC 3.A.1.17.1 / Q47538 TauB aka SSIB aka B0366, component of Taurine (2-aminoethane sulfonate) porter from Escherichia coli (see 4 papers)
51% identity, 97% coverage of query (260 bits)
Ac3H11_2560 ABC transporter for L-Histidine, ATPase component from Acidovorax sp. GW101-3H11
45% identity, 96% coverage of query (216 bits)
NRTD_SYNE7 / P38046 Nitrate import ATP-binding protein NrtD; EC 7.3.2.4 from Synechococcus elongatus (strain ATCC 33912 / PCC 7942 / FACHB-805) (Anacystis nidulans R2) (see paper)
TC 3.A.1.16.1 / P38046 NrtD, component of Four component nitrate/nitrite porter (see paper)
46% identity, 90% coverage of query (213 bits)
CMPD_SYNE7 / Q55108 Bicarbonate transport ATP-binding protein CmpD; EC 7.6.2.- from Synechococcus elongatus (strain ATCC 33912 / PCC 7942 / FACHB-805) (Anacystis nidulans R2) (see paper)
TC 3.A.1.16.3 / Q55108 CmpD, component of Bicarbonate porter (activated by low [CO2] mediated by CmpR; (Nishimura et al., 2008)) (see 2 papers)
43% identity, 93% coverage of query (206 bits)
TC 3.A.1.16.2 / O05347 CynD, component of Bispecific cyanate/nitrite transporter
48% identity, 84% coverage of query (202 bits)
AZOBR_RS18550 ABC transporter for nitrate, ATPase component from Azospirillum brasilense Sp245
44% identity, 97% coverage of query (194 bits)
CMPC_SYNE7 / Q55107 Bicarbonate transport ATP-binding protein CmpC; EC 7.6.2.- from Synechococcus elongatus (strain ATCC 33912 / PCC 7942 / FACHB-805) (Anacystis nidulans R2) (see paper)
TC 3.A.1.16.3 / Q55107 CmpC, component of Bicarbonate porter (activated by low [CO2] mediated by CmpR; (Nishimura et al., 2008)) (see 2 papers)
42% identity, 91% coverage of query (192 bits)
TC 3.A.1.16.4 / Q8YRV8 Nitrate transport ATP-binding protein of ABC transporter, component of Nitrate uptake system, NrtABCD from Nostoc sp. (strain PCC 7120 / UTEX 2576) (see paper)
41% identity, 96% coverage of query (187 bits)
NRTC_SYNE7 / P38045 Nitrate import ATP-binding protein NrtC; EC 7.3.2.4 from Synechococcus elongatus (strain ATCC 33912 / PCC 7942 / FACHB-805) (Anacystis nidulans R2) (see 2 papers)
TC 3.A.1.16.1 / P38045 NrtC, component of Four component nitrate/nitrite porter (see paper)
40% identity, 96% coverage of query (177 bits)
TC 3.A.1.17.5 / C0LZR9 OphH, component of The phthalate uptake system, OphFGH from Burkholderia cepacia
41% identity, 91% coverage of query (176 bits)
SSUB_BACSU / P97027 Aliphatic sulfonates import ATP-binding protein SsuB; EC 7.6.2.14 from Bacillus subtilis (strain 168) (see paper)
39% identity, 83% coverage of query (174 bits)
OUSV_DICD3 / E0SCY1 Glycine betaine/choline transport system ATP-binding protein OusV from Dickeya dadantii (strain 3937) (Erwinia chrysanthemi (strain 3937)) (see paper)
41% identity, 85% coverage of query (172 bits)
TC 3.A.1.12.9 / Q8U4S5 OtaA, component of The salt-induced glycine betaine OtaABC transporter from Methanosarcina mazei (see 2 papers)
37% identity, 90% coverage of query (170 bits)
PotG / b0855 putrescine ABC transporter ATP binding subunit (EC 7.6.2.11; EC 7.6.2.16) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
PotG / P31134 putrescine ABC transporter ATP binding subunit (EC 7.6.2.11) from Escherichia coli (strain K12) (see 2 papers)
POTG_ECOLI / P31134 Putrescine transport ATP-binding protein PotG; EC 7.6.2.16 from Escherichia coli (strain K12) (see 2 papers)
TC 3.A.1.11.2 / P31134 PotG aka B0855, component of Putrescine porter from Escherichia coli (see 4 papers)
41% identity, 85% coverage of query (162 bits)
OPUAA_BACSU / P46920 Glycine betaine transport ATP-binding protein OpuAA; Quaternary-amine-transporting ATPase; EC 7.6.2.9 from Bacillus subtilis (strain 168) (see 2 papers)
P46920 ABC-type quaternary amine transporter (EC 7.6.2.9) from Bacillus subtilis (see paper)
TC 3.A.1.12.2 / P46920 OPAA aka OpuAA, component of Glycine betaine OpuAA/AB/AC porter (also transports dimethylsulfonioacetate and dimethylsulfoniopropionate) from Bacillus subtilis (see 4 papers)
41% identity, 74% coverage of query (162 bits)
TC 3.A.1.11.6 / Q1M7Q1 Putative ABC transporter component, component of The γ-aminobutyrate (GABA) uptake system, GtsABCD from Rhizobium leguminosarum bv. viciae (strain 3841) (see paper)
44% identity, 79% coverage of query (159 bits)
SM_b21216 ABC transporter for D-Glucosamine, ATPase component from Sinorhizobium meliloti 1021
42% identity, 80% coverage of query (155 bits)
AO356_13805 ABC transporter for Carnitine, ATPase component from Pseudomonas fluorescens FW300-N2C3
41% identity, 72% coverage of query (153 bits)
Pf6N2E2_4681 ABC transporter for Carnitine, ATPase component from Pseudomonas fluorescens FW300-N2E2
41% identity, 72% coverage of query (152 bits)
PotA / b1126 spermidine preferential ABC transporter ATP binding subunit (EC 7.6.2.11; EC 7.6.2.16) from Escherichia coli K-12 substr. MG1655 (see 5 papers)
PotA / P69874 spermidine preferential ABC transporter ATP binding subunit (EC 7.6.2.11) from Escherichia coli (strain K12) (see 5 papers)
POTA_ECOLI / P69874 Spermidine/putrescine import ATP-binding protein PotA; EC 7.6.2.11 from Escherichia coli (strain K12) (see 6 papers)
TC 3.A.1.11.1 / P69874 Spermidine/putrescine import ATP-binding protein PotA aka B1126, component of Polyamine (putrescine/spermidine) uptake porter from Escherichia coli (see 9 papers)
potA / MB|P69874 spermidine/putrescine ABC transporter, ATP-binding protein PotA; EC 3.6.3.31 from Escherichia coli K12 (see 10 papers)
44% identity, 71% coverage of query (150 bits)
7ahhC Opua inhibited inward-facing, sbd docked
38% identity, 72% coverage of query (142 bits)
7aheC / Q9KIF7 Opua inhibited inward facing (see paper)
38% identity, 72% coverage of query (142 bits)
7ahdC Opua (e190q) occluded
38% identity, 72% coverage of query (142 bits)
2d62A / O57933 Crystal structure of multiple sugar binding transport atp- binding protein
38% identity, 72% coverage of query (134 bits)
Q8TTZ3 ABC-type molybdate transporter (EC 7.3.2.5) from Methanosarcina acetivorans (see paper)
3d31A / Q8TTZ3 Modbc from methanosarcina acetivorans (see paper)
37% identity, 72% coverage of query (132 bits)
1f3oA / Q58206 Crystal structure of mj0796 atp-binding cassette (see paper)
40% identity, 72% coverage of query (132 bits)
1l2tA Dimeric structure of mj0796, a bacterial abc transporter cassette
40% identity, 72% coverage of query (130 bits)
8hplC / A0R2C0 Lpqy-sugabc in state 1 (see paper)
38% identity, 73% coverage of query (130 bits)
1g291 / Q9YGA6 Malk (see paper)
35% identity, 86% coverage of query (130 bits)
5xu1B / Q8DQF8 Structure of a non-canonical abc transporter from streptococcus pneumoniae r6 (see paper)
38% identity, 71% coverage of query (129 bits)
sugC / P9WQI3 ABC-type trehalose transporter ATP-binding protein from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 2 papers)
SUGC_MYCTU / P9WQI3 Trehalose import ATP-binding protein SugC; MtbSugC; Nucleotide-binding domain of SugABC transporter; NBD of SugABC transporter; SugABC transporter ATPase SugC; EC 7.5.2.- from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 2 papers)
TC 3.A.1.1.31 / O50454 PROBABLE SUGAR-TRANSPORT ATP-BINDING PROTEIN ABC TRANSPORTER SUGC, component of The trehalose-recycling ABC transporter, LpqY-SugA-SugB-SugC (essential for virulence) from Mycobacterium tuberculosis (see 2 papers)
38% identity, 72% coverage of query (128 bits)
8hprD Lpqy-sugabc in state 4
38% identity, 72% coverage of query (128 bits)
8hprC Lpqy-sugabc in state 4
38% identity, 72% coverage of query (127 bits)
MetN / b0199 L-methionine/D-methionine ABC transporter ATP binding subunit (EC 7.4.2.11) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
MetN / P30750 L-methionine/D-methionine ABC transporter ATP binding subunit (EC 7.4.2.11) from Escherichia coli (strain K12) (see 3 papers)
METN_ECOLI / P30750 Methionine import ATP-binding protein MetN; EC 7.4.2.11 from Escherichia coli (strain K12) (see 7 papers)
P30750 ABC-type methionine transporter (subunit 2/2) (EC 7.4.2.11) from Escherichia coli (see 3 papers)
TC 3.A.1.24.1 / P30750 MetN, D-methionine transport ATP-binding protein, component of The L- and D-methionine porter (also transports formyl-L-methionine and other methionine derivatives) (Zhang et al., 2003). The 3.7A structure of MetNI has been solved. An allosteric regulatory mechanism operates at the level of transport activity, so increased intracellular levels of the transported ligand stabilize an inward-facing, ATPase-inactive state of MetNI to inhibit further ligand translocation into the cell from Escherichia coli (see 5 papers)
35% identity, 84% coverage of query (125 bits)
MALK_SALTY / P19566 Maltose/maltodextrin import ATP-binding protein MalK; EC 7.5.2.1 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
38% identity, 78% coverage of query (125 bits)
3tuzC Inward facing conformations of the metni methionine abc transporter: cy5 semet soak crystal form
34% identity, 84% coverage of query (124 bits)
3tuiC Inward facing conformations of the metni methionine abc transporter: cy5 native crystal form
34% identity, 84% coverage of query (124 bits)
6cvlD / P30750 Crystal structure of the escherichia coli atpgs-bound metni methionine abc transporter in complex with its metq binding protein (see paper)
34% identity, 84% coverage of query (124 bits)
2awnB / P68187 Crystal structure of the adp-mg-bound e. Coli malk (crystallized with atp-mg) (see paper)
38% identity, 78% coverage of query (124 bits)
1q12A Crystal structure of the atp-bound e. Coli malk
38% identity, 78% coverage of query (124 bits)
3puyA Crystal structure of an outward-facing mbp-maltose transporter complex bound to amp-pnp after crystal soaking of the pretranslocation state
38% identity, 78% coverage of query (124 bits)
3puxA Crystal structure of an outward-facing mbp-maltose transporter complex bound to adp-bef3
38% identity, 78% coverage of query (124 bits)
3puwA Crystal structure of an outward-facing mbp-maltose transporter complex bound to adp-alf4
38% identity, 78% coverage of query (124 bits)
3puvA Crystal structure of an outward-facing mbp-maltose transporter complex bound to adp-vo4
38% identity, 78% coverage of query (124 bits)
MalK / b4035 maltose ABC transporter ATP binding subunit (EC 7.5.2.1) from Escherichia coli K-12 substr. MG1655 (see 31 papers)
MalK / P68187 maltose ABC transporter ATP binding subunit (EC 7.5.2.1) from Escherichia coli (strain K12) (see 29 papers)
MALK_ECOLI / P68187 Maltose/maltodextrin import ATP-binding protein MalK; EC 7.5.2.1 from Escherichia coli (strain K12) (see 6 papers)
P68187 ABC-type maltose transporter (subunit 3/3) (EC 7.5.2.1) from Escherichia coli (see paper)
TC 3.A.1.1.1 / P68187 Maltose/maltodextrin import ATP-binding protein MalK aka B4035, component of Maltooligosaccharide porter. The 3-D structure has been reported by Oldham et al. (2007). An altering access mechanism has been suggested for the maltose transporter resulting from rigid-body rotations (Khare et al., 2009). Bordignon et al. (2010) and Schneider et al. (2012) have reviewed the extensive knowledge available on MalEFGK2, its mode of action and its regulatory interactions from Escherichia coli (see 17 papers)
malK / RF|NP_418459 maltose/maltodextrin import ATP-binding protein malK; EC 3.6.3.19 from Escherichia coli K12 (see 18 papers)
38% identity, 78% coverage of query (124 bits)
1oxvD Crystal structure of glcv, the abc-atpase of the glucose abc transporter from sulfolobus solfataricus
37% identity, 77% coverage of query (122 bits)
1oxvA Crystal structure of glcv, the abc-atpase of the glucose abc transporter from sulfolobus solfataricus
37% identity, 77% coverage of query (122 bits)
GLCV_SACS2 / Q97UY8 Glucose import ATP-binding protein GlcV; EC 7.5.2.- from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus) (see 3 papers)
TC 3.A.1.1.13 / Q97UY8 GlcV, component of Glucose, mannose, galactose porter from Sulfolobus solfataricus (see 3 papers)
1oxuA / Q97UY8 Crystal structure of glcv, the abc-atpase of the glucose abc transporter from sulfolobus solfataricus (see paper)
37% identity, 77% coverage of query (122 bits)
3fvqB / Q5FA19 Crystal structure of the nucleotide binding domain fbpc complexed with atp (see paper)
41% identity, 71% coverage of query (120 bits)
4u00A / Q5SJ55 Crystal structure of ttha1159 in complex with adp (see paper)
38% identity, 86% coverage of query (117 bits)
LolD / b1117 lipoprotein release complex - ATP binding subunit from Escherichia coli K-12 substr. MG1655 (see 2 papers)
LolD / P75957 lipoprotein release complex - ATP binding subunit from Escherichia coli (strain K12) (see paper)
LOLD_ECOLI / P75957 Lipoprotein-releasing system ATP-binding protein LolD; EC 7.6.2.- from Escherichia coli (strain K12) (see paper)
TC 3.A.1.125.1 / P75957 LolD aka B1117, component of Lipoprotein translocation system (translocates lipoproteins from the inner membrane to periplasmic chaperone, LolA, which transfers the lipoproteins to an outer membrane receptor, LolB, which anchors the lipoprotein to the outer membrane of the Gram-negative bacterial cell envelope) (see 1.B.46; Narita et al., 2003; Ito et al., 2006; Watanabe et al., 2007). The structure of ligand-bound LolCDE has been solved (Ito et al., 2006). LolC and LolE each have 4 TMSs (1+3). Unlike most ATP binding cassette transporters mediating the transmembrane flux of substrates, the LolCDE complex catalyzes the extrusion of lipoproteins anchored to the outer leaflet of the inner membrane. The LolCDE complex is unusual in that it can be purified as a liganded form, which is an intermediate of the lipoprotein release reaction (Taniguchi and Tokuda, 2008). LolCDE has been reconstituted from separated subunits from Escherichia coli (see 5 papers)
lolD / GB|BAA35937.2 lipoprotein releasing system, ATP-binding protein; EC 3.6.3.- from Escherichia coli K12 (see 5 papers)
38% identity, 72% coverage of query (116 bits)
7v8iD / P75957 Lolcd(e171q)e with bound amppnp in nanodiscs (see paper)
37% identity, 72% coverage of query (115 bits)
4ymuJ / Q8RCC2 Crystal structure of an amino acid abc transporter complex with arginines and atps (see paper)
36% identity, 72% coverage of query (114 bits)
2awnC / P68187 Crystal structure of the adp-mg-bound e. Coli malk (crystallized with atp-mg) (see paper)
36% identity, 77% coverage of query (113 bits)
5lj7A / Q2EHL8 Structure of aggregatibacter actinomycetemcomitans macb bound to atp (p21) (see paper)
35% identity, 74% coverage of query (112 bits)
5lilA / Q2EHL8 Structure of aggregatibacter actinomycetemcomitans macb bound to atpys (p21) (see paper)
35% identity, 74% coverage of query (111 bits)
1vciA / O57758 Crystal structure of the atp-binding cassette of multisugar transporter from pyrococcus horikoshii ot3 complexed with atp (see paper)
37% identity, 72% coverage of query (111 bits)
3c4jA Abc protein artp in complex with atp-gamma-s
33% identity, 77% coverage of query (106 bits)
3c41J / D0VWX4 Abc protein artp in complex with amp-pnp/mg2+
33% identity, 77% coverage of query (106 bits)
2olkA Abc protein artp in complex with adp-beta-s
33% identity, 77% coverage of query (106 bits)
2oljA Abc protein artp in complex with adp/mg2+
33% identity, 77% coverage of query (106 bits)
P0AAH0 Phosphate import ATP-binding protein PstB; ABC phosphate transporter; Phosphate-transporting ATPase; EC 7.3.2.1 from Escherichia coli (strain K12)
33% identity, 75% coverage of query (104 bits)
8iddA Cryo-em structure of mycobacterium tuberculosis atp bound ftsex/ripc complex in peptidisc
36% identity, 77% coverage of query (104 bits)
8igqA / O05779 Cryo-em structure of mycobacterium tuberculosis adp bound ftsex/ripc complex in peptidisc (see paper)
36% identity, 77% coverage of query (103 bits)
FTSE_MYCTA / A5U7B7 Cell division ATP-binding protein FtsE from Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra) (see 2 papers)
36% identity, 77% coverage of query (103 bits)
7chaI / Q9HVW1 Cryo-em structure of p.Aeruginosa mlafebd with amppnp (see paper)
37% identity, 72% coverage of query (103 bits)
8tzjA / A0A085R4L6 Cryo-em structure of vibrio cholerae ftse/ftsx complex (see paper)
36% identity, 71% coverage of query (103 bits)
5ws4A / A0A0D8G707 Crystal structure of tripartite-type abc transporter macb from acinetobacter baumannii (see paper)
33% identity, 91% coverage of query (102 bits)
7w78A / Q6NEF2 Heme exporter hrtba in complex with mg-amppnp (see paper)
34% identity, 89% coverage of query (101 bits)
7w79A Heme exporter hrtba in complex with mn-amppnp
38% identity, 79% coverage of query (101 bits)
ABCA3_HUMAN / Q99758 Phospholipid-transporting ATPase ABCA3; ABC-C transporter; ATP-binding cassette sub-family A member 3; ATP-binding cassette transporter 3; ATP-binding cassette 3; Xenobiotic-transporting ATPase ABCA3; EC 7.6.2.1; EC 7.6.2.2 from Homo sapiens (Human) (see 18 papers)
TC 3.A.1.211.5 / Q99758 The surfactant-secreting porter, ABCA3 (exports lipids and proteins into lamellar bodies). Fatal surfactant deficiency (FSD) can result from mutations in ABCA3, causing abnormal intracellular localization (type I) or decreased ATP hydrolysis (type II). Other mutations cause pediatric interstitial lung disease (pILD) from Homo sapiens (Human) (see 7 papers)
ABCA3 / RF|NP_001080.2 ATP-binding cassette sub-family A member 3 from Homo sapiens (see paper)
30% identity, 80% coverage of query (101 bits)
P9WQK5 Uncharacterized ABC transporter ATP-binding protein Rv0073 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
35% identity, 80% coverage of query (100 bits)
Build an alignment for BPHYT_RS02460 and 74 homologs with ≥ 30% identity
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7w02A / Q99758 Cryo-em structure of atp-bound abca3 (see paper)
29% identity, 80% coverage of query (99.8 bits)
8i6rB / Q9I6C0 Cryo-em structure of pseudomonas aeruginosa ftse(e163q)x/envc complex with atp in peptidisc (see paper)
37% identity, 78% coverage of query (98.6 bits)
ABCA3_MOUSE / Q8R420 Phospholipid-transporting ATPase ABCA3; ATP-binding cassette sub-family A member 3; Xenobiotic-transporting ATPase ABCA3; EC 7.6.2.1; EC 7.6.2.2 from Mus musculus (Mouse) (see 7 papers)
28% identity, 80% coverage of query (98.2 bits)
8bmpA Cryo-em structure of the folate-specific ecf transporter complex in msp2n2 lipid nanodiscs bound to atp and adp
31% identity, 93% coverage of query (97.8 bits)
6z4wA / Q8DQH4 Ftse structure from streptococcus pneumoniae in complex with adp (space group p 1) (see paper)
31% identity, 80% coverage of query (97.4 bits)
5d3mA / Q1GBJ0 Folate ecf transporter: amppnp bound state (see paper)
31% identity, 89% coverage of query (96.3 bits)
8w6iD / P0A9R7 Cryo-em structure of escherichia coli str k12 ftsex complex with atp- gamma-s in peptidisc
35% identity, 78% coverage of query (96.3 bits)
FtsE / b3463 cell division protein FtsE from Escherichia coli K-12 substr. MG1655 (see 9 papers)
FTSE_ECOLI / P0A9R7 Cell division ATP-binding protein FtsE from Escherichia coli (strain K12) (see 4 papers)
ftsE cell division ATP-binding protein ftsE from Escherichia coli K12 (see 3 papers)
35% identity, 78% coverage of query (96.3 bits)
7d0aB Acinetobacter mlafedb complex in adp-vanadate trapped vclose conformation
33% identity, 77% coverage of query (96.3 bits)
7d08B / A0A086HZU3 Acinetobacter mlafedb complex in atp-bound vtrans1 conformation (see paper)
33% identity, 77% coverage of query (96.3 bits)
6z67B Ftse structure of streptococcus pneumoniae in complex with amppnp at 2.4 a resolution
32% identity, 72% coverage of query (95.9 bits)
6z5uK Cryo-em structure of the a. Baumannii mlabdef complex bound to appnhp
33% identity, 77% coverage of query (95.9 bits)
7ch8I Cryo-em structure of p.Aeruginosa mlafebd with adp-v
38% identity, 72% coverage of query (95.9 bits)
8bmsA Cryo-em structure of the mutant solitary ecf module 2eq in msp2n2 lipid nanodiscs in the atpase closed and atp-bound conformation
30% identity, 93% coverage of query (95.5 bits)
8hd0A Cell divisome spg hydrolysis machinery ftsex-envc
35% identity, 78% coverage of query (95.1 bits)
4zirA Crystal structure of ecfaa' heterodimer bound to amppnp
32% identity, 78% coverage of query (94.7 bits)
4hluA / Q9WY65 Structure of the ecfa-a' heterodimer bound to adp (see paper)
32% identity, 78% coverage of query (94.4 bits)
ABCA1_HUMAN / O95477 Phospholipid-transporting ATPase ABCA1; ATP-binding cassette sub-family A member 1; ATP-binding cassette transporter 1; ABC-1; ATP-binding cassette 1; Cholesterol efflux regulatory protein; EC 7.6.2.1 from Homo sapiens (Human) (see 34 papers)
TC 3.A.1.211.14 / O95477 cAMP-dependent and sulfonylurea-sensitive anion transporter, ABCA1 of 2261 aas. Key gatekeeper influencing and possibly catalyzing intracellular phospholipid and cholesterol transport from Homo sapiens
31% identity, 72% coverage of query (89.7 bits)
ABCA1_MOUSE / P41233 Phospholipid-transporting ATPase ABCA1; ATP-binding cassette sub-family A member 1; ATP-binding cassette transporter 1; ABC-1; ATP-binding cassette 1; EC 7.6.2.1 from Mus musculus (Mouse) (see 2 papers)
31% identity, 72% coverage of query (89.7 bits)
ECFA2_STRT2 / Q5M244 Energy-coupling factor transporter ATP-binding protein EcfA2; ECF transporter A component EcfA2; EC 3.6.3.- from Streptococcus thermophilus (strain ATCC BAA-250 / LMG 18311) (see paper)
TC 3.A.1.25.6 / Q5M244 Energy-coupling factor transporter ATP-binding protein EcfA 1, component of Riboflavin ECF transport system, EcfAA'T/RibU from Streptococcus thermophilus (strain ATCC BAA-250 / LMG 18311)
31% identity, 72% coverage of query (89.0 bits)
7tbwA / O95477 The structure of atp-bound abca1 (see paper)
30% identity, 72% coverage of query (88.2 bits)
4yerA / Q9X1C3 Crystal structure of an abc transporter atp-binding protein (tm_1403) from thermotoga maritima msb8 at 2.35 a resolution
32% identity, 72% coverage of query (85.9 bits)
8f5bA / P78363 Human abca4 structure in complex with amp-pnp
30% identity, 80% coverage of query (85.5 bits)
ABCA9_HUMAN / Q8IUA7 ATP-binding cassette sub-family A member 9; EC 7.6.2.- from Homo sapiens (Human) (see paper)
TC 3.A.1.211.16 / Q8IUA7 ATP-binding cassette sub-family A member 9, ABCA9 of 1624 aas. May play a role in monocyte differentiation and lipid homeostasis. Expressed in fetal tissues with highest expression in fetal heart and kidney. Up-regulated during monocyte differentiation into macrophages. Down-regulated by cholesterol loading of macrophages from Homo sapiens
31% identity, 74% coverage of query (85.1 bits)
7e7oA / P78363 Cryo-em structure of human abca4 in nrpe-bound state (see paper)
28% identity, 72% coverage of query (84.3 bits)
8ee6A / Q8IZY2 Cryo-em structure of human abca7 in pe/ch nanodiscs (see paper)
31% identity, 86% coverage of query (84.0 bits)
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Lawrence Berkeley National Laboratory