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Searching for up to 100 curated homologs for BPHYT_RS07260 FitnessBrowser__BFirm:BPHYT_RS07260 (143 a.a.)

Found high-coverage hits (≥70%) to 20 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

nbaF / Q83V27 2-aminomuconate deaminase (EC 3.5.99.5) from Pseudomonas fluorescens (see paper)
    71% identity, 94% coverage of query (205 bits)

amnD / Q9KWS2 2-aminomuconate deaminase monomer (EC 3.5.99.5) from Pseudomonas sp. (see 2 papers)
AMND_PSESP / Q9KWS2 2-aminomuconate deaminase; EC 3.5.99.5 from Pseudomonas sp. (see 2 papers)
    65% identity, 99% coverage of query (194 bits)

RIDA_PYRFU / Q8U308 2-iminobutanoate/2-iminopropanoate deaminase; Enamine/imine deaminase; EC 3.5.99.10 from Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1) (see paper)
Q8U308 2-iminobutanoate/2-iminopropanoate deaminase (EC 3.5.99.10) from Pyrococcus furiosus (see paper)
    41% identity, 86% coverage of query (96.7 bits)

Q973T6 2-iminobutanoate/2-iminopropanoate deaminase (EC 3.5.99.10) from Sulfurisphaera tokodaii (see paper)
    37% identity, 85% coverage of query (75.9 bits)

Build an alignment

Build an alignment for BPHYT_RS07260 and 4 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

MMF1_YEAST / P40185 Protein MMF1, mitochondrial; Isoleucine biosynthesis and maintenance of intact mitochondria 1; Maintenance of mitochondrial function 1 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 3 papers)
    29% identity, 97% coverage of query (70.9 bits)

HMF1_YEAST / P40037 Protein HMF1; High dosage growth inhibitor; Homologous mitochondrial matrix factor 1 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 2 papers)
    32% identity, 78% coverage of query (68.6 bits)

2b33B / Q9WY58 Crystal structure of a putative endoribonuclease (tm0215) from thermotoga maritima msb8 at 2.30 a resolution
    36% identity, 85% coverage of query (66.6 bits)

YhaR / b3113 putative enamine/imine deaminase from Escherichia coli K-12 substr. MG1655 (see 2 papers)
TDCF_ECOLI / P0AGL2 Putative reactive intermediate deaminase TdcF; EC 3.5.4.- from Escherichia coli (strain K12) (see paper)
    29% identity, 90% coverage of query (66.6 bits)

2uykC / P0AGL2 Crystal structure of e. Coli tdcf with bound serine (see paper)
    29% identity, 90% coverage of query (66.2 bits)

2uynA Crystal structure of e. Coli tdcf with bound 2-ketobutyrate
    29% identity, 90% coverage of query (66.2 bits)

ahdB / B5U8R1 2-amino-5-carboxymuconic 6-semialdehyde deaminase subunit from Bordetella sp. 10d (see paper)
    34% identity, 79% coverage of query (62.4 bits)

RIDA_ARATH / Q94JQ4 Reactive Intermediate Deaminase A, chloroplastic; 2-iminobutanoate/2-iminopropanoate deaminase; EC 3.5.99.10 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
Q94JQ4 2-iminobutanoate/2-iminopropanoate deaminase (EC 3.5.99.10) from Arabidopsis thaliana (see paper)
    30% identity, 83% coverage of query (61.6 bits)

5hp8A / Q94JQ4 Crystal structures of rida in complex with pyruvate (see paper)
    31% identity, 78% coverage of query (58.5 bits)

RIDA_DERFA / A0A1J1DL12 2-iminobutanoate/2-iminopropanoate deaminase; Allergen Der f 34; Enamine/imine deaminase; Allergen Der f 34.0101; EC 3.5.99.10 from Dermatophagoides farinae (American house dust mite) (see paper)
    26% identity, 87% coverage of query (57.8 bits)

Q880Z0 2-iminobutanoate/2-iminopropanoate deaminase (EC 3.5.99.10) from Pseudomonas syringae pv. tomato (see paper)
    31% identity, 83% coverage of query (55.5 bits)

3lybB Structure of putative endoribonuclease(kp1_3112) from klebsiella pneumoniae
    27% identity, 80% coverage of query (54.7 bits)

YcdK / b1010 putative aminoacrylate peracid reductase RutC from Escherichia coli K-12 substr. MG1655 (see 7 papers)
rutC / P0AFQ5 3-aminoacrylate deaminase from Escherichia coli (strain K12) (see 8 papers)
RUTC_ECOLI / P0AFQ5 3-aminoacrylate deaminase RutC; 3-AA deaminase; EC 3.5.-.- from Escherichia coli (strain K12) (see 5 papers)
RUTC_ECOL6 / P0AFQ6 3-aminoacrylate deaminase RutC; 3-AA deaminase; EC 3.5.-.- from Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) (see paper)
    28% identity, 90% coverage of query (54.3 bits)

UK114_DROME / Q9V3W0 RutC family protein UK114 from Drosophila melanogaster (Fruit fly) (see paper)
    27% identity, 94% coverage of query (54.3 bits)

3k0tC / Q88BE5 Crystal structure of pspto -psp protein in complex with d-beta-glucose from pseudomonas syringae pv. Tomato str. Dc3000 (see paper)
    27% identity, 83% coverage of query (52.8 bits)

YjgH / b4248 RutC family protein YjgH from Escherichia coli K-12 substr. MG1655 (see 2 papers)
yjgH / RF|NP_418669 UPF0076 protein yjgH from Escherichia coli K12 (see paper)
    29% identity, 86% coverage of query (46.6 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory