Searching for up to 100 curated homologs for BPHYT_RS07265 FitnessBrowser__BFirm:BPHYT_RS07265 (174 a.a.)
Found high-coverage hits (≥70%) to 22 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
3HAO_CUPMC / Q1LCS4 3-hydroxyanthranilate 3,4-dioxygenase; 3-hydroxyanthranilate oxygenase; 3-HAO; 3-hydroxyanthranilic acid dioxygenase; HAD; EC 1.13.11.6 from Cupriavidus metallidurans (strain ATCC 43123 / DSM 2839 / NBRC 102507 / CH34) (Ralstonia metallidurans) (see 2 papers)
88% identity, 100% coverage of query (331 bits)
4i3pA 1.96 angstrom x-ray crystal structure of 3-hydroxyanthranilate-3,4- dioxygenase bound with 3-aminosalicylic acid from cupriavidus metallidurans
88% identity, 100% coverage of query (331 bits)
4hvoA 1.75 angstrom x-ray crystal structure of cufe reconstituted 3- hydroxyanthranilate-3,4-dioxygenase from cupriavidus metallidurans
88% identity, 100% coverage of query (331 bits)
4hsjA 1.88 angstrom x-ray crystal structure of piconlinic-bound 3- hydroxyanthranilate-3,4-dioxygenase
88% identity, 100% coverage of query (331 bits)
1yfxA Crystal structure of 3-hydroxyanthranilate-3,4-dioxygenase from ralstonia metallidurans complexed with 4-chloro-3-hydroxyanthranilic acid and no
88% identity, 100% coverage of query (331 bits)
1yfwA Crystal structure of 3-hydroxyanthranilate-3,4-dioxygenase from ralstonia metallidurans complexed with 4-chloro-3-hydroxyanthranilic acid and o2
88% identity, 100% coverage of query (331 bits)
6vi8A / Q1LCS4 Observing a ring-cleaving dioxygenase in action through a crystalline lens - a superoxo bound structure (see paper)
88% identity, 100% coverage of query (330 bits)
6vibA Observing a ring-cleaving dioxygenase in action through a crystalline lens - enol tautomers of acms bidentately bound structure
88% identity, 100% coverage of query (330 bits)
6viaA Observing a ring-cleaving dioxygenase in action through a crystalline lens - a seven-membered lactone bound structure
88% identity, 100% coverage of query (330 bits)
4wzcA Understanding extradiol dioxygenase mechanism in NAD+ biosynthesis by viewing catalytic intermediates - 2,3-cis-4,5-trans acms bound to i142a mutant hao
87% identity, 100% coverage of query (328 bits)
6vi9A Observing a ring-cleaving dioxygenase in action through a crystalline lens - an alkylperoxo bound structure
89% identity, 98% coverage of query (327 bits)
nbaC / Q83V26 3-hydroxyanthranilate 3,4-dioxygenase subunit (EC 1.13.11.6) from Pseudomonas fluorescens (see paper)
3HAO_PSEFL / Q83V26 3-hydroxyanthranilate 3,4-dioxygenase; 3-hydroxyanthranilate oxygenase; 3-HAO; 3-hydroxyanthranilic acid dioxygenase; HAD; EC 1.13.11.6 from Pseudomonas fluorescens (see paper)
Q83V26 3-hydroxyanthranilate 3,4-dioxygenase (EC 1.13.11.6) from Pseudomonas fluorescens (see paper)
nbaC / BAC65311.1 3-hydroxyanthranilate 3,4-dioxygenase from Pseudomonas fluorescens (see paper)
74% identity, 100% coverage of query (282 bits)
nbaC / A4IT48 3-hydroxyanthranilate 3,4-dioxygenase (EC 1.13.11.6) from Geobacillus thermodenitrificans (strain NG80-2) (see paper)
44% identity, 98% coverage of query (166 bits)
3HAO_YEAST / P47096 3-hydroxyanthranilate 3,4-dioxygenase; 3-hydroxyanthranilate oxygenase; 3-HAO; 3-hydroxyanthranilic acid dioxygenase; HAD; Biosynthesis of nicotinic acid protein 1; EC 1.13.11.6 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 4 papers)
P47096 3-hydroxyanthranilate 3,4-dioxygenase (EC 1.13.11.6) from Saccharomyces cerevisiae (see paper)
39% identity, 91% coverage of query (113 bits)
3HAO_BOVIN / Q0VCA8 3-hydroxyanthranilate 3,4-dioxygenase; 3-hydroxyanthranilate oxygenase; 3-HAO; 3-hydroxyanthranilic acid dioxygenase; HAD; EC 1.13.11.6 from Bos taurus (Bovine) (see paper)
Q0VCA8 3-hydroxyanthranilate 3,4-dioxygenase (EC 1.13.11.6) from Bos taurus (see paper)
35% identity, 89% coverage of query (99.8 bits)
3fe5A / Q0VCA8 Crystal structure of 3-hydroxyanthranilate 3,4-dioxygenase from bovine kidney (see paper)
35% identity, 89% coverage of query (99.4 bits)
HAAO / P46952 3-hydroxyanthranilate 3,4-dioxygenase (EC 1.13.11.6) from Homo sapiens (see 2 papers)
3HAO_HUMAN / P46952 3-hydroxyanthranilate 3,4-dioxygenase; 3-hydroxyanthranilate oxygenase; 3-HAO; h3HAO; 3-hydroxyanthranilic acid dioxygenase; HAD; EC 1.13.11.6 from Homo sapiens (Human) (see 3 papers)
P46952 3-hydroxyanthranilate 3,4-dioxygenase (EC 1.13.11.6) from Homo sapiens (see 2 papers)
36% identity, 85% coverage of query (99.4 bits)
5tk5A / P46952 Crystal structure of human 3hao with iron bound in the active site (see paper)
36% identity, 85% coverage of query (99.0 bits)
5tkqA Crystal structure of human 3hao with zinc bound in the active site
36% identity, 85% coverage of query (99.0 bits)
3HAO_MOUSE / Q78JT3 3-hydroxyanthranilate 3,4-dioxygenase; 3-hydroxyanthranilate oxygenase; 3-HAO; 3-hydroxyanthranilic acid dioxygenase; HAD; EC 1.13.11.6 from Mus musculus (Mouse) (see paper)
35% identity, 86% coverage of query (98.2 bits)
3HAO_RAT / P46953 3-hydroxyanthranilate 3,4-dioxygenase; 3-hydroxyanthranilate oxygenase; 3-HAO; 3-hydroxyanthranilic acid dioxygenase; HAD; EC 1.13.11.6 from Rattus norvegicus (Rat) (see paper)
35% identity, 86% coverage of query (95.9 bits)
Build an alignment for BPHYT_RS07265 and 21 homologs with ≥ 30% identity
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ahdA / Q76CA9 4-amino-3-hydroxy-benzoate 2,3-dioxygenase subunit from Bordetella sp. 10d (see paper)
ahdA / BAD08206.1 4-amino-3-hydroxybenzoate 2,3-dioxygenase from Bordetella sp. 10d (see paper)
29% identity, 84% coverage of query (75.5 bits)
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Lawrence Berkeley National Laboratory