Searching for up to 100 curated homologs for BPHYT_RS11060 FitnessBrowser__BFirm:BPHYT_RS11060 (392 a.a.)
Found high-coverage hits (≥70%) to 54 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
7on9A / C4TP09 Crystal structure of para-hydroxybenzoate-3-hydroxylase prai (see paper)
61% identity, 99% coverage of query (500 bits)
PRAI_PAESP / C4TP09 4-hydroxybenzoate 3-monooxygenase (NAD(P)H); 4-hydroxybenzoate 3-hydroxylase; 4HB 3-hydroxylase; EC 1.14.13.33 from Paenibacillus sp. (see paper)
praI / BAH79107.1 4-hydroxybenzoate 3-hydroxylase from Paenibacillus sp. JJ-1b (see paper)
61% identity, 99% coverage of query (499 bits)
PHHY_PSEAE / P20586 p-hydroxybenzoate hydroxylase; PHBH; 4-hydroxybenzoate 3-monooxygenase; EC 1.14.13.2 from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see 7 papers)
1d7lA / P20586 Structure-function correlations of the reaction of reduced nicotinamide analogs with p-hydroxybenzoate hydroxylase substituted with a series of 8-substituted flavins (see paper)
53% identity, 99% coverage of query (413 bits)
1iusA P-hydroxybenzoate hydroxylase complexed with 4-aminobenzoate at ph 5.0
53% identity, 99% coverage of query (413 bits)
1dodA The mobil flavin of 4-oh benzoate hydroxylase: motion of a prosthetic group regulates catalysis
53% identity, 99% coverage of query (413 bits)
1bf3A P-hydroxybenzoate hydroxylase (phbh) mutant with cys 116 replaced by ser (c116s) and arg 42 replaced by lys (r42k), in complex with fad and 4-hydroxybenzoic acid
52% identity, 99% coverage of query (412 bits)
1pbcA Crystal structures of wild-type p-hydroxybenzoate hydroxylase complexed with 4-aminobenzoate, 2,4-dihydroxybenzoate and 2-hydroxy- 4-aminobenzoate and of the try222ala mutant, complexed with 2- hydroxy-4-aminobenzoate. Evidence for a proton channel and a new binding mode of the flavin ring
52% identity, 99% coverage of query (412 bits)
pobA / P00438 p-hydroxybenzoate hydroxylase (EC 1.14.13.2) from Pseudomonas fluorescens (see 2 papers)
PHHY_PSEFL / P00438 p-hydroxybenzoate hydroxylase; PHBH; PHBHase; 4-hydroxybenzoate 3-monooxygenase; EC 1.14.13.2 from Pseudomonas fluorescens (see 13 papers)
52% identity, 99% coverage of query (411 bits)
1k0lA Pseudomonas aeruginosa phbh r220q free of p-ohb
52% identity, 99% coverage of query (410 bits)
1k0jA Pseudomonas aeruginosa phbh r220q in complex with NADPH and free of p- ohb
52% identity, 99% coverage of query (410 bits)
2phhA The coenzyme analogue adenosine 5-diphosphoribose displaces fad in the active site of p-hydroxybenzoate hydroxylase. An x-ray crystallographic investigation
52% identity, 99% coverage of query (410 bits)
1pdhA Crystal structure of p-hydroxybenzoate hydroxylase reconstituted with the modified fad present in alcohol oxidase from methylotrophic yeasts: evidence for an arabinoflavin
52% identity, 99% coverage of query (410 bits)
Pf6N2E2_2914 4-hydroxybenzoate 3-monooxygenase (EC 1.14.13.2) from Pseudomonas fluorescens FW300-N2E2
51% identity, 99% coverage of query (404 bits)
RR42_RS21940 4-hydroxybenzoate 3-monooxygenase (EC 1.14.13.2) from Cupriavidus basilensis FW507-4G11
53% identity, 99% coverage of query (404 bits)
1ykjB A45g p-hydroxybenzoate hydroxylase with p-hydroxybenzoate bound
52% identity, 99% coverage of query (403 bits)
pobA / Q9R9T1 p-hydroxybenzoate hydroxylase (EC 1.14.13.2) from Pseudomonas putida (see paper)
Q9R9T1 4-hydroxybenzoate 3-monooxygenase (EC 1.14.13.2) from Pseudomonas putida (see paper)
49% identity, 99% coverage of query (385 bits)
pobA / AAA73519.1 4-hydroxybenzoate hydroxylase from Rhizobium leguminosarum (see paper)
49% identity, 99% coverage of query (384 bits)
8jqoA Protocatecuate hydroxylase from xylophilus ampelinus complexed with imidazole (see paper)
48% identity, 99% coverage of query (381 bits)
6dllB / Q88H28 2.2 angstrom resolution crystal structure of p-hydroxybenzoate hydroxylase from pseudomonas putida in complex with fad. (see paper)
48% identity, 99% coverage of query (380 bits)
pobA / F2JUE7 4-hydroxybenzoate 3-monooxygenase (EC 1.14.13.2) from Marinomonas mediterranea (strain ATCC 700492 / JCM 21426 / NBRC 103028 / MMB-1) (see paper)
47% identity, 99% coverage of query (365 bits)
8jqoD Protocatecuate hydroxylase from xylophilus ampelinus complexed with imidazole (see paper)
39% identity, 98% coverage of query (275 bits)
Build an alignment for BPHYT_RS11060 and 21 homologs with ≥ 30% identity
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tsdB / Q0SFL5 resorcinol 4-hydroxylase (NADH) (EC 1.14.13.220) from Rhodococcus jostii (strain RHA1) (see 2 papers)
TSDB_RHOJR / Q0SFL5 Probable NADH-specific resorcinol 4-hydroxylase; EC 1.14.13.220 from Rhodococcus jostii (strain RHA1) (see paper)
26% identity, 83% coverage of query (77.8 bits)
oxyS / L8EUQ6 anhydrotetracycline monooxygenase monomer (EC 1.14.13.234; EC 1.14.13.38) from Streptomyces rimosus subsp. rimosus (strain ATCC 10970 / DSM 40260 / JCM 4667 / NRRL 2234) (see 6 papers)
OXYS_STRR1 / L8EUQ6 12-dehydrotetracycline 5-monooxygenase/anhydrotetracycline 6-monooxygenase; EC 1.14.13.234; EC 1.14.13.38 from Streptomyces rimosus subsp. rimosus (strain ATCC 10970 / DSM 40260 / JCM 4667 / NRRL 2234) (see paper)
L8EUQ6 5a,11a-dehydrotetracycline 5-monooxygenase (EC 1.14.13.234) from Streptomyces rimosus subsp. rimosus (see paper)
28% identity, 84% coverage of query (71.2 bits)
4k2xB / L8EUQ6 Oxys anhydrotetracycline hydroxylase from streptomyces rimosus (see paper)
27% identity, 84% coverage of query (69.7 bits)
OTCC_STRRM / Q58PK7 Anhydrotetracycline monooxygenase; EC 1.14.13.38 from Streptomyces rimosus (see paper)
Q58PK7 anhydrotetracycline 6-monooxygenase (EC 1.14.13.38) from Streptomyces rimosus (see paper)
28% identity, 84% coverage of query (69.3 bits)
SDNN_SORAA / A0A1B4XBH7 FAD-dependent monooxygenase sdnN; Sordarin/hypoxysordarin biosynthesis cluster protein N; EC 1.-.-.- from Sordaria araneosa (Pleurage araneosa) (see paper)
24% identity, 79% coverage of query (64.7 bits)
6u0sA Crystal structure of the flavin-dependent monooxygenase piee in complex with fad and substrate
26% identity, 78% coverage of query (62.8 bits)
6u0pC / W0C4C9 Crystal structure of piee, the flavin-dependent monooxygenase involved in the biosynthesis of piericidin a1 (see paper)
26% identity, 78% coverage of query (62.4 bits)
7oujAAA / Q8KY42 7oujAAA (see paper)
28% identity, 74% coverage of query (61.6 bits)
8fhjC Crystal structure of a fad monooxygenease from methylocystis sp. Strain sb2 (see paper)
24% identity, 94% coverage of query (60.8 bits)
PYRE3_STRRG / K7QRJ5 Dialkyldecalin synthase; FAD-dependent [4+2] cyclase; EC 5.5.1.- from Streptomyces rugosporus (see 2 papers)
25% identity, 78% coverage of query (60.5 bits)
5xgvA / K7QRJ5 The structure of diels-alderase pyre3 in the biosynthetic pathway of pyrroindomycins (see paper)
25% identity, 76% coverage of query (59.3 bits)
ROX_STRVP / F2R776 Rifampicin monooxygenase; RIFMO; EC 1.14.13.211 from Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745) (see paper)
23% identity, 85% coverage of query (58.2 bits)
6brdA / F2R776 Crystal structure of rifampin monooxygenase from streptomyces venezuelae, complexed with rifampin and fad (see paper)
23% identity, 85% coverage of query (58.2 bits)
hspB / F8G0M4 6-hydroxy-3-succinoyl-pyridine hydroxylase monomer (EC 1.14.13.163) from Pseudomonas putida (strain DSM 28022 / S16) (see paper)
HSPB_PSEP6 / F8G0M4 6-hydroxy-3-succinoylpyridine 3-monooxygenase HspB; 6-hydroxy-3-succinoylpyridine hydroxylase; HSP hydroxylase; EC 1.14.13.163 from Pseudomonas putida (strain DSM 28022 / S16) (see 2 papers)
F8G0M4 6-hydroxy-3-succinoylpyridine 3-monooxygenase (EC 1.14.13.163) from Pseudomonas putida (see paper)
25% identity, 84% coverage of query (57.8 bits)
6ui5A / Q1MX79 Tmn9 in complex with cofactor fad
24% identity, 82% coverage of query (57.4 bits)
Cgl1158 / Q8NR94 resorcinol 4-hydroxylase (NADPH) (EC 1.14.13.219) from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) (see 2 papers)
RES4H_CORGL / Q8NR94 NADPH-dependent resorcinol 4-hydroxylase; Resorcinol hydroxylase; EC 1.14.13.219 from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) (see paper)
24% identity, 89% coverage of query (55.8 bits)
DPMAE_METAN / P9WEY1 FAD-dependent monooxygenase dpmaE; Diterpenoid pyrone biosynthesis cluster protein E; EC 1.-.-.- from Metarhizium anisopliae (Entomophthora anisopliae) (see paper)
22% identity, 95% coverage of query (55.8 bits)
1-NH / A0A140DCH8 1-naphthol 2-hydroxylase monomer from Pseudomonas sp. C5pp (see 5 papers)
22% identity, 83% coverage of query (54.7 bits)
orf19.5443 kynurenine 3-monooxygenase; EC 1.14.13.9 from Candida albicans (see 2 papers)
23% identity, 79% coverage of query (53.1 bits)
NTNK_NECSZ / A0A455M7R7 FAD-dependent monooxygenase ntnK; Nectripenoid biosynthesis cluster protein K; EC 1.-.-.- from Nectria sp. (see paper)
23% identity, 80% coverage of query (52.8 bits)
6c7sA Structure of rifampicin monooxygenase with product bound
25% identity, 82% coverage of query (52.0 bits)
5koxA Structure of rifampicin monooxygenase complexed with rifampicin
25% identity, 82% coverage of query (52.0 bits)
ROX_NOCFA / Q5YTV5 Rifampicin monooxygenase; RIFMO; EC 1.14.13.211 from Nocardia farcinica (strain IFM 10152) (see 3 papers)
Q5YTV5 rifampicin monooxygenase (EC 1.14.13.211) from Nocardia farcinica (see paper)
25% identity, 82% coverage of query (52.0 bits)
5kowA / Q5YTV5 Structure of rifampicin monooxygenase (see paper)
25% identity, 82% coverage of query (52.0 bits)
7yj0D Structural basis of oxepinone formation by a flavin-monooxygenase vibo
24% identity, 79% coverage of query (52.0 bits)
jadF / Q5U915 UWM6 dehydratase from Streptomyces venezuelae (see 4 papers)
26% identity, 82% coverage of query (51.6 bits)
DNRF_STRPE / P32009 Aklavinone 12-hydroxylase DnrF; Aklavinone 11-hydroxylase; EC 1.14.13.180 from Streptomyces peucetius (see paper)
P32009 aklavinone 12-hydroxylase (EC 1.14.13.180) from Streptomyces peucetius (see paper)
dnrF / AAC43342.1 aklavinone C-11 hydroxylase from Streptomyces peucetius (see paper)
24% identity, 74% coverage of query (51.2 bits)
dnrF / P72495 aklavinone 12-hydroxylase (EC 1.14.13.180) from Streptomyces peucetius subsp. caesius (see paper)
DNRF_STRC0 / P72495 Aklavinone 12-hydroxylase DnrF; Aklavinone 11-hydroxylase; EC 1.14.13.180 from Streptomyces peucetius subsp. caesius (see paper)
P72495 aklavinone 12-hydroxylase (EC 1.14.13.180) from Streptomyces peucetius (see paper)
dnrF / AAA62496.1 aklavinone C-11 hydroxylase from Streptomyces peucetius (see paper)
23% identity, 79% coverage of query (50.1 bits)
A5LGH2 2,4-dichlorophenol 6-monooxygenase (EC 1.14.13.20) from Bradyrhizobium sp. (see paper)
24% identity, 80% coverage of query (50.1 bits)
DNRF_STREF / Q54530 Aklavinone 12-hydroxylase RdmE; Aklavinone 11-hydroxylase; EC 1.14.13.180 from Streptomyces purpurascens (see 2 papers)
Q54530 aklavinone 12-hydroxylase (EC 1.14.13.180) from Streptomyces purpurascens (see paper)
3ihgA / Q54530 Crystal structure of a ternary complex of aklavinone-11 hydroxylase with fad and aklavinone (see paper)
23% identity, 76% coverage of query (49.7 bits)
MO1_ARATH / O81815 Monooxygenase 1; AtMO1; EC 1.14.13.- from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
24% identity, 81% coverage of query (47.4 bits)
vppD / A0A075XAG5 6-hydroxy-3-succinoyl-pyridine hydroxylase (EC 1.14.13.163) from Ochrobactrum sp. SJY1 (see 2 papers)
A0A075XAG5 6-hydroxy-3-succinoylpyridine 3-monooxygenase (EC 1.14.13.163) from Ochrobactrum sp. (see paper)
24% identity, 81% coverage of query (47.4 bits)
W8E0Y0 6-hydroxy-3-succinoylpyridine 3-monooxygenase (EC 1.14.13.163) from Agrobacterium tumefaciens (see 2 papers)
24% identity, 81% coverage of query (47.0 bits)
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Lawrence Berkeley National Laboratory