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Searching for up to 100 curated homologs for BPHYT_RS15540 FitnessBrowser__BFirm:BPHYT_RS15540 (640 a.a.)

Found high-coverage hits (≥70%) to 15 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

GsiA / b0829 glutathione ABC transporter ATP binding subunit GsiA (EC 7.4.2.10) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
gsiA / P75796 glutathione ABC transporter ATP binding subunit GsiA (EC 7.4.2.10) from Escherichia coli (strain K12) (see 3 papers)
GSIA_ECOLI / P75796 Glutathione import ATP-binding protein GsiA; EC 7.4.2.10 from Escherichia coli (strain K12) (see paper)
P75796 ABC-type glutathione transporter (EC 7.4.2.10) from Escherichia coli (see paper)
TC 3.A.1.5.11 / P75796 Hypothetical ABC transporter ATP-binding protein yliA, component of Glutathione porter, YliABCD or GsiABCD from Escherichia coli (see 4 papers)
    66% identity, 98% coverage of query (823 bits)

Q8ZQM4 ABC-type glutathione transporter (EC 7.4.2.10) from Salmonella enterica subsp. enterica serovar Typhimurium (see paper)
    66% identity, 98% coverage of query (816 bits)

TC 3.A.1.5.26 / P63395 Uncharacterized ABC transporter ATP-binding protein Rv1281c/MT1318, component of The glutathione transporter, OppA (Dasgupta et al., 2010). OppA binds glutathione and the nanopeptide, bradykinin. Also regulates cytokine release, apoptosis and the innate immune response of macrophages infected with M. tuberculosis from Mycobacterium tuberculosis (see 2 papers)
    46% identity, 90% coverage of query (476 bits)

YejF / b2180 putative oligopeptide ABC transporter ATP binding subunit YejF (EC 7.4.2.6) from Escherichia coli K-12 substr. MG1655 (see 6 papers)
YejF / P33916 putative oligopeptide ABC transporter ATP binding subunit YejF (EC 7.4.2.6) from Escherichia coli (strain K12) (see 3 papers)
TC 3.A.1.5.21 / P33916 YejF, component of The Microcin C/peptide uptake porter, YejABEF from Escherichia coli (strain K12) (see 3 papers)
yejF / RF|NP_416685 uncharacterized ABC transporter ATP-binding protein yejF from Escherichia coli K12 (see paper)
    47% identity, 89% coverage of query (474 bits)

TC 3.A.1.5.24 / Q8ZNJ8 YejF, component of The antimicrobial peptide (protamine, melittin, polymyxin B, human defensin (HBD)-1 and HBD-2 exporter, YejABEF (Eswarappa et al., 2008). Prefers N-formyl methionine peptides, such as Microcin C (of prokaryotic origin) to non formylated peptides (of eukaryotic origin) from Salmonella typhimurium (see paper)
    47% identity, 88% coverage of query (460 bits)

TC 3.A.1.5.23 / Q9F9T4 EppD, component of The Ethylene diamine tetraacetate (EDTA) uptake porter, EppABCD (see 2 papers)
    44% identity, 92% coverage of query (449 bits)

SM_b21644 ABC transporter for D-Raffinose, ATPase component from Sinorhizobium meliloti 1021
    46% identity, 89% coverage of query (446 bits)

TC 3.A.1.5.8 / Q97UG5 MalK, component of Maltose and maltooligosaccharide porter from Sulfolobus solfataricus (see paper)
    34% identity, 90% coverage of query (332 bits)

TC 3.A.1.5.17 / Q92NE8 PrbD, component of The proline betaine uptake porter from Rhizobium meliloti (Sinorhizobium meliloti) (see paper)
    35% identity, 86% coverage of query (316 bits)

Build an alignment

Build an alignment for BPHYT_RS15540 and 9 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

1yqtA Rnase-l inhibitor
    25% identity, 80% coverage of query (83.2 bits)

5yv5A Crystal structure of the complex of archaeal ribosomal stalk protein ap1 and archaeal ribosome recycling factor aabce1.
    25% identity, 80% coverage of query (83.2 bits)

3bk7A / Q9UZA4 Structure of the complete abce1/rnaase-l inhibitor protein from pyrococcus abysii (see paper)
    24% identity, 80% coverage of query (77.8 bits)

3j5sD / P0A9W3 Etta binds to ribosome exit site and regulates translation by restricting ribosome and tRNA dynamics (see paper)
    24% identity, 88% coverage of query (76.6 bits)

YjjK / b4391 energy-dependent translational throttle protein EttA from Escherichia coli K-12 substr. MG1655 (see 9 papers)
ETTA_ECOLI / P0A9W3 Energy-dependent translational throttle protein EttA; Translational regulatory factor EttA; EC 3.6.1.- from Escherichia coli (strain K12) (see 2 papers)
CH_004211 ABC transporter, ATP-binding protein YjiK from Escherichia coli K12 (see paper)
    24% identity, 88% coverage of query (76.3 bits)

ETTA_ECOL6 / A0A0H2VFI8 Energy-dependent translational throttle protein EttA; Translational regulatory factor EttA; EC 3.6.1.- from Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) (see paper)
    24% identity, 88% coverage of query (76.3 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory