Searching for up to 100 curated homologs for BPHYT_RS15795 FitnessBrowser__BFirm:BPHYT_RS15795 (281 a.a.)
Found high-coverage hits (≥70%) to 100 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
5c7hA / Q92NR7 Crystal structure of aldo-keto reductase from sinorhizobium meliloti 1021 in complex with NADPH
55% identity, 100% coverage of query (307 bits)
4pmjA Crystal structure of a putative oxidoreductase from sinorhizobium meliloti 1021 in complex with NADP
55% identity, 100% coverage of query (307 bits)
YeaE / b1781 methylglyoxal reductase YeaE from Escherichia coli K-12 substr. MG1655 (see 4 papers)
yeaE / P76234 methylglyoxal reductase YeaE (EC 1.1.1.21) from Escherichia coli (strain K12) (see 3 papers)
54% identity, 95% coverage of query (297 bits)
6ciaA / A6T7Q7 Crystal structure of aldo-keto reductase from klebsiella pneumoniae in complex with NADPH.
52% identity, 98% coverage of query (290 bits)
4wghA Crystal structure of aldo/keto reductase from klebsiella pneumoniae in complex with NADP and acetate at 1.8 a resolution
52% identity, 98% coverage of query (290 bits)
Q9X265 carbonyl reductase (NADPH) (EC 1.1.1.184) from Thermotoga maritima (see 2 papers)
41% identity, 91% coverage of query (191 bits)
6kikA / Q9X265 Crystal structure of a thermostable aldo-keto reductase tm1743 in complex with inhibitor tolrestat (see paper)
41% identity, 91% coverage of query (191 bits)
5danA Crystal structure of a novel aldo keto reductase tm1743 from thermotoga maritima in complex with NADP+
41% identity, 91% coverage of query (191 bits)
6kiyA Crystal structure of a thermostable aldo-keto reductase tm1743 in complex with inhibitor epalrestat
41% identity, 91% coverage of query (191 bits)
Q8TZM9 alcohol dehydrogenase (EC 1.1.1.1) from Pyrococcus furiosus (see 2 papers)
37% identity, 88% coverage of query (140 bits)
Q5JI09 alcohol dehydrogenase (EC 1.1.1.1) from Thermococcus kodakarensis (see paper)
35% identity, 88% coverage of query (134 bits)
GS69_BACSU / P80874 Aldo-keto reductase YhdN; AKR11B; General stress protein 69; GSP69; EC 1.1.1.- from Bacillus subtilis (strain 168) (see 3 papers)
32% identity, 77% coverage of query (109 bits)
1pz1A / P80874 Structure of NADPH-dependent family 11 aldo-keto reductase akr11b(holo) (see paper)
32% identity, 77% coverage of query (107 bits)
Build an alignment for BPHYT_RS15795 and 13 homologs with ≥ 30% identity
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DkgB / b0207 methylglyoxal reductase DkgB (EC 1.1.1.91; EC 1.1.1.346) from Escherichia coli K-12 substr. MG1655 (see 6 papers)
dkgB / P30863 methylglyoxal reductase DkgB (EC 1.1.1.21; EC 1.1.1.91; EC 1.1.1.346) from Escherichia coli (strain K12) (see 5 papers)
dkgB / MB|P30863 2,5-diketo-D-gluconic acid reductase B; EC 1.1.1.274 from Escherichia coli K12 (see 5 papers)
28% identity, 90% coverage of query (104 bits)
1vbjA / Q9GV41 The crystal structure of prostaglandin f synthase from trypanosoma brucei
29% identity, 93% coverage of query (103 bits)
PGFS_TRYBB / Q9GV41 9,11-endoperoxide prostaglandin H2 reductase; Prostaglandin F2-alpha synthase; EC 1.1.1.- from Trypanosoma brucei brucei (see paper)
29% identity, 93% coverage of query (103 bits)
4g5dA / P22045 X-ray crystal structure of prostaglandin f synthase from leishmania major friedlin bound to NADPH (see paper)
29% identity, 93% coverage of query (102 bits)
PGFS_LEIMA / P22045 9,11-endoperoxide prostaglandin H2 reductase; Prostaglandin F2-alpha synthase; EC 1.1.1.- from Leishmania major (see paper)
P22045 prostaglandin-F synthase (EC 1.1.1.188) from Leishmania major (see paper)
29% identity, 93% coverage of query (102 bits)
akr5f1 organophosphate reductase from Klebsiella sp. F51-1-2 (see paper)
32% identity, 94% coverage of query (101 bits)
F2YCN5 D-xylose reductase (EC 1.1.1.307) from Zymomonas mobilis subsp. mobilis (see paper)
29% identity, 89% coverage of query (101 bits)
A0QV10 Aldo-keto reductase MSMEG_2408/MSMEI_2347; EC 1.1.1.- from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis)
30% identity, 92% coverage of query (99.8 bits)
GCY1 putative uncharacterized protein from Candida albicans (see paper)
31% identity, 88% coverage of query (99.4 bits)
A0A3P3ZE14 prostaglandin-F synthase (EC 1.1.1.188) from Leishmania braziliensis (see paper)
29% identity, 93% coverage of query (98.6 bits)
6ow0B / Q194Q1 Crystal structure of mithramycin 3-side chain keto-reductase mtmw in complex with NAD+ and peg (see paper)
30% identity, 82% coverage of query (97.8 bits)
Q4DJ07 prostaglandin-F synthase (EC 1.1.1.188) from Trypanosoma cruzi (see paper)
28% identity, 95% coverage of query (97.8 bits)
1m9hA Corynebacterium 2,5-dkgr a and phe 22 replaced with tyr (f22y), lys 232 replaced with gly (k232g), arg 238 replaced with his (r238h)and ala 272 replaced with gly (a272g)in presence of nadh cofactor
32% identity, 94% coverage of query (97.8 bits)
4gieA / Q4DJ07 Crystal structure of prostaglandin f synthase from trypanosoma cruzi bound to NADP (see paper)
28% identity, 95% coverage of query (97.4 bits)
1pz0A / P46336 Structure of NADPH-dependent family 11 aldo-keto reductase akr11a(holo) (see paper)
28% identity, 83% coverage of query (97.1 bits)
Y2407_MYCS2 / A0QV09 Aldo-keto reductase MSMEG_2407/MSMEI_2346; AKR; AKR5H1; EC 1.1.1.- from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis) (see paper)
29% identity, 95% coverage of query (97.1 bits)
2wzmA / A0QV09 Crystal structure of a mycobacterium aldo-keto reductase in its apo and liganded form (see paper)
29% identity, 95% coverage of query (96.7 bits)
dkgA / P06632 2,5-diketo-D-gluconate reductase A monomer (EC 1.1.1.346) from Corynebacterium sp. (strain ATCC 31090) (see 4 papers)
DKGA_CORSC / P06632 2,5-diketo-D-gluconic acid reductase A; 2,5-DKG reductase A; 2,5-DKGR A; 25DKGR-A; AKR5C; EC 1.1.1.346 from Corynebacterium sp. (strain ATCC 31090) (see 2 papers)
P06632 2,5-didehydrogluconate reductase (2-dehydro-L-gulonate-forming) (EC 1.1.1.346) from Corynebacterium sp. (see paper)
32% identity, 94% coverage of query (96.7 bits)
1a80A / P06632 Native 2,5-diketo-d-gluconic acid reductase a from corynbacterium sp. Complexed with NADPH (see paper)
32% identity, 94% coverage of query (96.7 bits)
5az1A Crystal structure of aldo-keto reductase (akr2e5) complexed with nadph (see paper)
29% identity, 98% coverage of query (96.7 bits)
4fziA Crystal structure of prostaglandin f synthase from trypanosoma cruzi
29% identity, 92% coverage of query (95.9 bits)
IOLS_BACSU / P46336 Aldo-keto reductase IolS; AKR11A; Vegetative protein 147; VEG147; EC 1.1.1.- from Bacillus subtilis (strain 168) (see 4 papers)
28% identity, 82% coverage of query (95.1 bits)
E3W861 carbonyl reductase (NADPH) (EC 1.1.1.184) from Bacillus sp. (in: Bacteria) (see paper)
3b3dA / O34678 B.Subtilis ytbe (see paper)
31% identity, 95% coverage of query (94.4 bits)
YBN4_SCHPO / O42888 Uncharacterized oxidoreductase C8E4.04; EC 1.-.-.- from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
27% identity, 93% coverage of query (94.4 bits)
yvgN / O32210 glyoxal/methylglyoxal reductase (EC 1.1.1.283; EC 1.1.1.91) from Bacillus subtilis (strain 168) (see 3 papers)
GR_BACSU / O32210 Glyoxal reductase; GR; Methylglyoxal reductase; EC 1.1.1.-; EC 1.1.1.283 from Bacillus subtilis (strain 168) (see paper)
31% identity, 100% coverage of query (94.0 bits)
3d3fA / O32210 Crystal structure of yvgn and cofactor NADPH from bacillus subtilis (see paper)
31% identity, 100% coverage of query (94.0 bits)
YajO / b0419 1-deoxyxylulose-5-phosphate synthase YajO from Escherichia coli K-12 substr. MG1655 (see 7 papers)
yajO / P77735 1-deoxyxylulose-5-phosphate synthase YajO from Escherichia coli (strain K12) (see 6 papers)
YAJO_ECOLI / P77735 1-deoxyxylulose-5-phosphate synthase YajO; EC 1.1.-.- from Escherichia coli (strain K12) (see 2 papers)
P77735 1-deoxy-D-xylulose-5-phosphate synthase (EC 2.2.1.7) from Escherichia coli (see paper)
26% identity, 91% coverage of query (93.6 bits)
BN592_00768 / R7AF73 NAD(P)-dependent bile acid 3β-dehydrogenase (EC 1.1.1.391) from Eggerthella sp. CAG:298 (see 2 papers)
R7AF73 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific) (EC 1.1.1.213); 3beta-hydroxysteroid 3-dehydrogenase (EC 1.1.1.270) from Eggerthella sp. CAG:298 (see paper)
28% identity, 94% coverage of query (92.4 bits)
AKR1C1 / Q04828 aldo-keto reductase family 1 member C1 (EC 1.1.1.149; EC 1.1.1.213; EC 1.1.1.112; EC 1.3.1.20) from Homo sapiens (see 13 papers)
AK1C1_HUMAN / Q04828 Aldo-keto reductase family 1 member C1; 20-alpha-hydroxysteroid dehydrogenase; 20-alpha-HSD; Chlordecone reductase homolog HAKRC; Dihydrodiol dehydrogenase 1; DD1; High-affinity hepatic bile acid-binding protein; HBAB; EC 1.1.1.-; EC 1.1.1.112; EC 1.1.1.209; EC 1.1.1.210; EC 1.1.1.357; EC 1.1.1.51; EC 1.1.1.53; EC 1.1.1.62; EC 1.3.1.20; EC 1.1.1.149 from Homo sapiens (Human) (see 8 papers)
Q04828 20alpha-hydroxysteroid dehydrogenase (EC 1.1.1.149); 3beta-hydroxysteroid 3-dehydrogenase (EC 1.1.1.270); 3alpha-hydroxysteroid 3-dehydrogenase (EC 1.1.1.357); 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific) (EC 1.1.1.50); trans-1,2-dihydrobenzene-1,2-diol dehydrogenase (EC 1.3.1.20) from Homo sapiens (see 13 papers)
29% identity, 95% coverage of query (92.0 bits)
AKR1C2 / P52895 3α hydroxysteroid dehydrogenase III (EC 1.1.1.52; EC 1.1.1.395; EC 1.1.1.213; EC 1.1.1.357) from Homo sapiens (see 12 papers)
AK1C2_HUMAN / P52895 Aldo-keto reductase family 1 member C2; 3-alpha-HSD3; Chlordecone reductase homolog HAKRD; Dihydrodiol dehydrogenase 2; DD-2; DD2; Dihydrodiol dehydrogenase/bile acid-binding protein; DD/BABP; Type III 3-alpha-hydroxysteroid dehydrogenase; EC 1.-.-.-; EC 1.1.1.112; EC 1.1.1.209; EC 1.1.1.53; EC 1.1.1.62; EC 1.3.1.20; EC 1.1.1.357 from Homo sapiens (Human) (see 9 papers)
P52895 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific) (EC 1.1.1.213); 3alpha-hydroxysteroid 3-dehydrogenase (EC 1.1.1.357); 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific) (EC 1.1.1.50); trans-1,2-dihydrobenzene-1,2-diol dehydrogenase (EC 1.3.1.20) from Homo sapiens (see 9 papers)
29% identity, 95% coverage of query (92.0 bits)
AK1C1_MACFU / Q95JH6 Aldo-keto reductase family 1 member C1; 20-alpha-hydroxysteroid dehydrogenase; 20-alpha-HSD; Dihydrodiol dehydrogenase 1; DD-1; DD1; EC 1.1.1.-; EC 1.1.1.112; EC 1.1.1.209; EC 1.1.1.210; EC 1.1.1.357; EC 1.1.1.51; EC 1.1.1.53; EC 1.1.1.62; EC 1.3.1.20; EC 1.1.1.149 from Macaca fuscata fuscata (Japanese macaque) (see paper)
28% identity, 95% coverage of query (92.0 bits)
3v0sA / Q3L181 Crystal structure of perakine reductase, founder member of a novel akr subfamily with unique conformational changes during NADPH binding (see paper)
29% identity, 90% coverage of query (90.9 bits)
4jtrB Akr1c2 complex with ibuprofen
29% identity, 94% coverage of query (90.5 bits)
6ow0A / Q194Q1 Crystal structure of mithramycin 3-side chain keto-reductase mtmw in complex with NAD+ and peg (see paper)
30% identity, 82% coverage of query (90.1 bits)
4l1wA / P52895 Crystal structuer of human 3-alpha hydroxysteroid dehydrogenase type 3 in complex with NADP+ and progesterone (see paper)
29% identity, 94% coverage of query (90.1 bits)
DkgA / b3012 methylglyoxal reductase DkgA (EC 1.1.1.346) from Escherichia coli K-12 substr. MG1655 (see 10 papers)
dkgA / Q46857 methylglyoxal reductase DkgA (EC 1.1.1.21; EC 1.1.1.346) from Escherichia coli (strain K12) (see 9 papers)
Q46857 2,5-didehydrogluconate reductase (2-dehydro-L-gulonate-forming) (EC 1.1.1.346) from Escherichia coli (see paper)
29% identity, 96% coverage of query (90.1 bits)
4xo7A Crystal structure of human 3-alpha hydroxysteroid dehydrogenase type 3 in complex with NADP+, 5alpha-androstan-3,17-dione and (3beta, 5alpha)-3-hydroxyandrostan-17-one
29% identity, 94% coverage of query (90.1 bits)
2hdjA Crystal structure of human type 3 3alpha-hydroxysteroid dehydrogenase in complex with NADP(h)
29% identity, 94% coverage of query (90.1 bits)
1j96A Human 3alpha-hsd type 3 in ternary complex with NADP and testosterone
29% identity, 94% coverage of query (90.1 bits)
1ihiA Crystal structure of human type iii 3-alpha-hydroxysteroid dehydrogenase/bile acid binding protein (akr1c2) complexed with NADP+ and ursodeoxycholate
29% identity, 94% coverage of query (90.1 bits)
4xo6B Crystal structure of human 3-alpha hydroxysteroid dehydrogenase type 3 in complex with NADP+, 5alpha-androstan-3,17-dione and (3beta, 5alpha)-3-hydroxyandrostan-17-one
29% identity, 94% coverage of query (90.1 bits)
4xo6A Crystal structure of human 3-alpha hydroxysteroid dehydrogenase type 3 in complex with NADP+, 5alpha-androstan-3,17-dione and (3beta, 5alpha)-3-hydroxyandrostan-17-one
29% identity, 94% coverage of query (90.1 bits)
1xjbA Crystal structure of human type 3 3alpha-hydroxysteroid dehydrogenase in complex with NADP(h), citrate and acetate molecules
29% identity, 94% coverage of query (90.1 bits)
AK1C1_MACFA / Q95JH7 Aldo-keto reductase family 1 member C1; 20-alpha-hydroxysteroid dehydrogenase; 20-alpha-HSD; Dihydrodiol dehydrogenase 1; DD-1; DD1; EC 1.1.1.-; EC 1.1.1.112; EC 1.1.1.209; EC 1.1.1.210; EC 1.1.1.357; EC 1.1.1.51; EC 1.1.1.53; EC 1.1.1.62; EC 1.3.1.20; EC 1.1.1.149 from Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) (see paper)
28% identity, 95% coverage of query (89.7 bits)
3ufyA Akr1c3 complex with r-naproxen
30% identity, 92% coverage of query (89.4 bits)
3r94A Akr1c3 complex with flurbiprofen
30% identity, 92% coverage of query (89.4 bits)
3r8hA Akr1c3 complex with zomepirac
30% identity, 92% coverage of query (89.4 bits)
3r8gA Akr1c3 complex with ibuprofen
30% identity, 92% coverage of query (89.4 bits)
3r7mA Akr1c3 complex with sulindac
30% identity, 92% coverage of query (89.4 bits)
3r6iA Akr1c3 complex with meclofenamic acid
30% identity, 92% coverage of query (89.4 bits)
4jtrA Akr1c2 complex with ibuprofen
29% identity, 92% coverage of query (89.4 bits)
4jtqA Akr1c2 complex with flurbiprofen
29% identity, 92% coverage of query (89.4 bits)
4jqaA Akr1c2 complex with mefenamic acid
29% identity, 92% coverage of query (89.4 bits)
4jq4A Akr1c2 complex with indomethacin
29% identity, 92% coverage of query (89.4 bits)
4jq3A Akr1c2 complex with zomepirac
29% identity, 92% coverage of query (89.4 bits)
4jq2A Akr1c2 complex with sulindac
29% identity, 92% coverage of query (89.4 bits)
4jq1A Akr1c2 complex with naproxen
29% identity, 92% coverage of query (89.4 bits)
3r58A Akr1c3 complex with naproxen
30% identity, 92% coverage of query (89.4 bits)
4falA Crystal structure of human 17beta-hydroxysteroid dehydrogenase type 5 in complex with 3-((3,4-dihydroisoquinolin-2(1h)-yl)sulfonyl)-n- methylbenzamide (80)
30% identity, 92% coverage of query (89.0 bits)
3c3uA Crystal structure of akr1c1 in complex with NADP and 3,5- dichlorosalicylic acid
29% identity, 92% coverage of query (89.0 bits)
6ijxA Crystal structure of akr1c1 complexed with meclofenamic acid
29% identity, 92% coverage of query (89.0 bits)
6a7aA Akr1c1 complexed with new inhibitor with novel scaffold
29% identity, 92% coverage of query (89.0 bits)
4yvpA Crystal structure of akr1c1 complexed with glibenclamide
29% identity, 92% coverage of query (89.0 bits)
3ntyA Crystal structure of akr1c1 in complex with NADP and 5-phenyl,3- chlorosalicylic acid
29% identity, 92% coverage of query (89.0 bits)
3gugA Crystal structure of akr1c1 l308v mutant in complex with NADP and 3,5- dichlorosalicylic acid
29% identity, 92% coverage of query (89.0 bits)
4hmnA Crystal structure of human 17beta-hydroxysteroid dehydrogenase type 5 in complex with (4-(4-chlorophenyl)piperazin-1-yl)(morpholino) methanone (24)
30% identity, 92% coverage of query (89.0 bits)
4fa3A Crystal structure of human 17beta-hydroxysteroid dehydrogenase type 5 in complex with (r)-1-(naphthalen-2-ylsulfonyl)piperidine-3- carboxylic acid (86)
30% identity, 92% coverage of query (89.0 bits)
Q5FT75 carbonyl reductase (NADPH) (EC 1.1.1.184) from Gluconobacter oxydans (see paper)
27% identity, 95% coverage of query (88.6 bits)
4h7cA Crystal structure of human 17beta-hydroxysteroid dehydrogenase type 5 in complex with 1-{4-[(2-methyl-1-piperidinyl)sulfonyl]phenyl}-2- pyrrolidinone
30% identity, 92% coverage of query (88.6 bits)
DHB5_MOUSE / P70694 Estradiol 17 beta-dehydrogenase 5; 17-beta-HSD 5; EC 1.1.1.- from Mus musculus (Mouse) (see paper)
28% identity, 95% coverage of query (87.8 bits)
3wbwA / Q5FT75 Crystal structure of gox0644 in complex with NADPH
27% identity, 92% coverage of query (87.8 bits)
YH5B_SCHPO / O94315 Uncharacterized oxidoreductase C215.11c; EC 1.-.-.- from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
28% identity, 93% coverage of query (87.8 bits)
7x3oA Crystal structure of aldo-keto reductase 1c3 complexed with compound s07054
30% identity, 92% coverage of query (87.8 bits)
2ipjA Crystal structure of h3alpha-hydroxysteroid dehydrogenase type 3 mutant y24a in complex with NADP+ and epi-testosterone
29% identity, 94% coverage of query (87.8 bits)
4wdxA 17beta-hsd5 in complex with [4-(2-hydroxyethyl)piperidin-1-yl](5- methyl-1h-indol-2-yl)methanone
30% identity, 92% coverage of query (87.4 bits)
4wdwA 17beta-hsd5 in complex with 3,6-dihydropyridin-1(2h)-yl(5-methyl-1h- indol-2-yl)methanone
29% identity, 92% coverage of query (87.0 bits)
5uxfA Crystal structure of mouse recon (akr1c13) in complex with cyclic di- amp
27% identity, 95% coverage of query (87.0 bits)
GCY1_YEAST / P14065 Glycerol 2-dehydrogenase (NADP(+)); Galactose-inducible crystallin-like protein 1; EC 1.1.1.156 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 13 papers)
27% identity, 96% coverage of query (86.7 bits)
Y2971_MYCTU / P9WQA5 Aldo-keto reductase Rv2971; AKR; EC 1.1.1.- from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 3 papers)
30% identity, 92% coverage of query (86.7 bits)
4zfcB / P42330 Crystal structure of akr1c3 complexed with glicazide (see paper)
29% identity, 95% coverage of query (86.7 bits)
7twzA / A0A0H3GP70 Crystal structure of NADP-linked putative oxidoreductase from klebsiella pneumoniae
30% identity, 88% coverage of query (86.7 bits)
3r43A Akr1c3 complexed with mefenamic acid
30% identity, 92% coverage of query (86.7 bits)
AKR1C3 / P42330 aldo-keto reductase family 1 member C3 (EC 1.1.1.64; EC 1.1.1.213; EC 1.1.1.112; EC 1.1.1.357; EC 1.1.1.188) from Homo sapiens (see 15 papers)
AK1C3_HUMAN / P42330 Aldo-keto reductase family 1 member C3; 17-beta-hydroxysteroid dehydrogenase type 5; 17-beta-HSD 5; 3-alpha-HSD type II, brain; 3-alpha-hydroxysteroid dehydrogenase type 2; 3-alpha-HSD type 2; Chlordecone reductase homolog HAKRb; Dihydrodiol dehydrogenase 3; DD-3; DD3; Dihydrodiol dehydrogenase type I; HA1753; Prostaglandin F synthase; PGFS; Testosterone 17-beta-dehydrogenase 5; EC 1.1.1.-; EC 1.1.1.210; EC 1.1.1.53; EC 1.1.1.62; EC 1.1.1.357; EC 1.1.1.188; EC 1.1.1.239; EC 1.1.1.64 from Homo sapiens (Human) (see 14 papers)
P42330 prostaglandin-F synthase (EC 1.1.1.188); aldose reductase (EC 1.1.1.21); 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific) (EC 1.1.1.213); 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) (EC 1.1.1.239); 3alpha-hydroxysteroid 3-dehydrogenase (EC 1.1.1.357); 3(or 17)beta-hydroxysteroid dehydrogenase (EC 1.1.1.51); 17beta-estradiol 17-dehydrogenase (EC 1.1.1.62); testosterone 17beta-dehydrogenase (NADP+) (EC 1.1.1.64); trans-1,2-dihydrobenzene-1,2-diol dehydrogenase (EC 1.3.1.20) from Homo sapiens (see 38 papers)
29% identity, 95% coverage of query (86.3 bits)
AK2E4_BOMMO / H9JTG9 Aldo-keto reductase AKR2E4; 3-dehydroecdysone reductase; Aldo-keto reductase 2E; EC 1.1.1.- from Bombyx mori (Silk moth) (see paper)
30% identity, 97% coverage of query (86.3 bits)
Y2996_MYCBO / Q7TXI6 Aldo-keto reductase BQ2027_MB2996; EC 1.1.1.- from Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97) (see paper)
30% identity, 92% coverage of query (85.5 bits)
3wczA / H9JTG9 Crystal structure of bombyx mori aldo-keto reductase (akr2e4) in complex with NADP (see paper)
30% identity, 95% coverage of query (85.5 bits)
3cv6A / Q91WR5 The crystal structure of mouse 17-alpha hydroxysteroid dehydrogenase gg225.226pp mutant in complex with inhibitor and cofactor NADP+. (see paper)
27% identity, 95% coverage of query (85.1 bits)
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Lawrence Berkeley National Laboratory