Sites on a Tree

 

Searching for up to 100 curated homologs for BPHYT_RS17340 FitnessBrowser__BFirm:BPHYT_RS17340 (566 a.a.)

Found high-coverage hits (≥70%) to 12 curated proteins.

Removed hits that are identical to the query, leaving 11

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

H281DRAFT_05724 3-oxo-5,6-didehydrosuberyl-CoA semialdehyde dehydrogenase PaaZ (EC:1.2.1.91) from Paraburkholderia bryophila 376MFSha3.1
    93% identity, 100% coverage of query (1038 bits)

Build an alignment

Build an alignment for BPHYT_RS17340 and 1 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

ROCA2_BACSU / P94391 1-pyrroline-5-carboxylate dehydrogenase 2; P5C dehydrogenase 2; L-glutamate gamma-semialdehyde dehydrogenase; EC 1.2.1.88 from Bacillus subtilis (strain 168) (see 3 papers)
    26% identity, 74% coverage of query (87.8 bits)

Q65NN2 L-glutamate gamma-semialdehyde dehydrogenase (EC 1.2.1.88) from Bacillus licheniformis (see paper)
    27% identity, 74% coverage of query (85.9 bits)

Q9K9B2 L-glutamate gamma-semialdehyde dehydrogenase (EC 1.2.1.88) from Alkalihalobacillus halodurans (see paper)
    26% identity, 74% coverage of query (82.4 bits)

3hazA / Q89E26 Crystal structure of bifunctional proline utilization a (puta) protein (see paper)
    26% identity, 72% coverage of query (79.0 bits)

6bsnA Structure of proline utilization a (puta) with proline bound in remote sites
    26% identity, 72% coverage of query (74.3 bits)

bzaA / G2IKR4 aromatic aldehyde dehydrogenase (EC 1.2.1.67; EC 1.2.1.29) from Sphingobium sp. (strain NBRC 103272 / SYK-6) (see paper)
    27% identity, 84% coverage of query (69.3 bits)

LADH / A3LNE3 NAD(P)+ L-lactaldehyde dehydrogenase from Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545) (see paper)
    23% identity, 77% coverage of query (66.6 bits)

GAPN_STREI / Q3C1A6 NADP-dependent glyceraldehyde-3-phosphate dehydrogenase; Glyceraldehyde-3-phosphate dehydrogenase [NADP(+)]; GAPN; Non-phosphorylating glyceraldehyde 3-phosphate dehydrogenase; Triosephosphate dehydrogenase; EC 1.2.1.9 from Streptococcus equinus (Streptococcus bovis) (see paper)
Q3C1A6 glyceraldehyde-3-phosphate dehydrogenase (NADP+) (EC 1.2.1.9) from Streptococcus equinus (see paper)
    24% identity, 77% coverage of query (60.1 bits)

GabD / b2661 succinate-semialdehyde dehydrogenase (NADP+) GabD (EC 1.2.1.79) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
gabD / P25526 succinate-semialdehyde dehydrogenase (NADP+) GabD (EC 1.2.1.79; EC 1.2.1.20) from Escherichia coli (strain K12) (see 22 papers)
GABD_ECOLI / P25526 Succinate-semialdehyde dehydrogenase [NADP(+)] GabD; SSDH; Glutarate-semialdehyde dehydrogenase; EC 1.2.1.79; EC 1.2.1.- from Escherichia coli (strain K12) (see 4 papers)
P25526 succinate-semialdehyde dehydrogenase (NADP+) (EC 1.2.1.79) from Escherichia coli K-12 (see paper)
GB|AAC75708.1 succinate-semialdehyde dehydrogenase [NAD(P)+]; EC 1.2.1.16 from Escherichia coli K12 (see 5 papers)
    25% identity, 74% coverage of query (50.4 bits)

3jz4A / P25526 Crystal structure of e. Coli NADP dependent enzyme (see paper)
    25% identity, 74% coverage of query (49.3 bits)

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory