Searching for up to 100 curated homologs for BPHYT_RS20760 FitnessBrowser__BFirm:BPHYT_RS20760 (322 a.a.)
Found high-coverage hits (≥70%) to 34 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
3rc1A / B3TMR8 Crystal structure of kijd10, a 3-ketoreductase from actinomadura kijaniata incomplex with NADP and tdp-benzene (see paper)
32% identity, 98% coverage of query (147 bits)
KIJDR_ACTKI / B3TMR8 dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose 3-reductase; 3-ketoreductase; NADPH-dependent C3-ketoreductase; EC 1.1.1.384 from Actinomadura kijaniata (see paper)
B3TMR8 dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose 3-reductase (EC 1.1.1.384) from Actinomadura kijaniata (see paper)
32% identity, 98% coverage of query (147 bits)
mtmU / Q194Q3 D-oliose 4-ketoreductase from Streptomyces argillaceus (see paper)
37% identity, 71% coverage of query (132 bits)
GRA26_STRVN / Q9ZA33 dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose 3-reductase; Gra-orf26 protein; dTDP-3,4-diketo-2,6-dideoxyglucose 3-ketoreductase; EC 1.1.1.384 from Streptomyces violaceoruber
35% identity, 78% coverage of query (131 bits)
XDH2_HALVD / D4GP30 D-xylose 1-dehydrogenase (NADP(+)) 2; XDH 2; EC 1.1.1.179 from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii) (see paper)
D4GP30 D-xylose 1-dehydrogenase (NADP+, D-xylono-1,5-lactone-forming) (EC 1.1.1.179) from Haloferax volcanii (see paper)
32% identity, 98% coverage of query (131 bits)
oleW / Q9RR32 dTDP-3,4-diketo-2,6-dideoxy-D-glucose 3-ketoreductase (EC 1.1.1.384) from Streptomyces antibioticus (see paper)
OLEW_STRAT / Q9RR32 dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose 3-reductase; dTDP-3,4-diketo-2,6-dideoxyglucose 3-ketoreductase; EC 1.1.1.384 from Streptomyces antibioticus (see paper)
Q9RR32 dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose 3-reductase (EC 1.1.1.384) from Streptomyces antibioticus (see paper)
32% identity, 99% coverage of query (130 bits)
spnN / Q9ALN5 dTDP-3,4-diketo-2,6-dideoxy-D-glucose 3-ketoreductase (EC 1.1.1.384) from Saccharopolyspora spinosa (see paper)
SPNN_SACSN / Q9ALN5 dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose 3-reductase; dTDP-3,4-diketo-2,6-dideoxy-D-glucose 3-ketoreductase; EC 1.1.1.384 from Saccharopolyspora spinosa (see 2 papers)
Q9ALN5 dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose 3-reductase (EC 1.1.1.384) from Saccharopolyspora spinosa (see paper)
31% identity, 93% coverage of query (122 bits)
DHDH_CANLF / Q9TV68 Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase; Can2DD; D-xylose 1-dehydrogenase; D-xylose-NADP dehydrogenase; Dimeric dihydrodiol dehydrogenase; EC 1.3.1.20; EC 1.1.1.179 from Canis lupus familiaris (Dog) (Canis familiaris) (see 3 papers)
34% identity, 75% coverage of query (119 bits)
Q148L6 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase (EC 1.3.1.20) from Bos taurus (see paper)
34% identity, 75% coverage of query (118 bits)
Q9DBB8 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase (EC 1.3.1.20) from Mus musculus (see paper)
33% identity, 78% coverage of query (114 bits)
DHDH_PIG / Q9TV69 Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase; D-xylose 1-dehydrogenase; D-xylose-NADP dehydrogenase; Dimeric dihydrodiol dehydrogenase; Sus2DD; EC 1.3.1.20; EC 1.1.1.179 from Sus scrofa (Pig) (see 3 papers)
31% identity, 86% coverage of query (114 bits)
DHDH_HUMAN / Q9UQ10 Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase; D-xylose 1-dehydrogenase; D-xylose-NADP dehydrogenase; Dimeric dihydrodiol dehydrogenase; Hum2DD; EC 1.3.1.20; EC 1.1.1.179 from Homo sapiens (Human) (see paper)
33% identity, 77% coverage of query (114 bits)
DHDH_MACFU / Q7JK39 Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase; D-xylose 1-dehydrogenase; D-xylose-NADP dehydrogenase; Dimeric dihydrodiol dehydrogenase; Jmo2DD; EC 1.3.1.20; EC 1.1.1.179 from Macaca fuscata fuscata (Japanese macaque) (see 3 papers)
DHDH_MACFA / Q9TQS6 Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase; Cmo2DD; D-xylose 1-dehydrogenase; D-xylose-NADP dehydrogenase; Dimeric dihydrodiol dehydrogenase; EC 1.3.1.20; EC 1.1.1.179 from Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) (see paper)
Q9TQS6 D-xylose 1-dehydrogenase (NADP+, D-xylono-1,5-lactone-forming) (EC 1.1.1.179); trans-1,2-dihydrobenzene-1,2-diol dehydrogenase (EC 1.3.1.20) from Macaca fascicularis (see 2 papers)
32% identity, 77% coverage of query (112 bits)
2o4uX / Q9TQS6 Crystal structure of mammalian dimeric dihydrodiol dehydrogenase (see paper)
32% identity, 77% coverage of query (111 bits)
2poqX Dimeric dihydrodiol dehydrogenase complexed with inhibitor, isoascorbic acid
32% identity, 77% coverage of query (111 bits)
Q5R5J5 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase (EC 1.3.1.20) from Pongo abelii (see paper)
32% identity, 77% coverage of query (108 bits)
DHDH_RABIT / Q9TV70 Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase; D-xylose 1-dehydrogenase; D-xylose-NADP dehydrogenase; Dimeric dihydrodiol dehydrogenase; Ory2DD; EC 1.3.1.20; EC 1.1.1.179 from Oryctolagus cuniculus (Rabbit) (see 2 papers)
33% identity, 76% coverage of query (102 bits)
Build an alignment for BPHYT_RS20760 and 17 homologs with ≥ 30% identity
Or download the sequences
5a03C / Q9A8X3 Crystal structure of aldose-aldose oxidoreductase from caulobacter crescentus complexed with xylose (see paper)
26% identity, 99% coverage of query (101 bits)
5a06A Crystal structure of aldose-aldose oxidoreductase from caulobacter crescentus complexed with sorbitol
26% identity, 99% coverage of query (101 bits)
5a05A Crystal structure of aldose-aldose oxidoreductase from caulobacter crescentus complexed with maltotriose
26% identity, 99% coverage of query (101 bits)
5a04A Crystal structure of aldose-aldose oxidoreductase from caulobacter crescentus complexed with glucose
26% identity, 99% coverage of query (101 bits)
5a03E Crystal structure of aldose-aldose oxidoreductase from caulobacter crescentus complexed with xylose
26% identity, 99% coverage of query (101 bits)
5a02A Crystal structure of aldose-aldose oxidoreductase from caulobacter crescentus complexed with glycerol
26% identity, 99% coverage of query (101 bits)
jadP / Q939Q8 dTDP-3,4-didehydro-2,6-dideoxy-α-D-glucose reductase (EC 1.1.1.384) from Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745) (see paper)
Q939Q8 dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose 3-reductase (EC 1.1.1.384) from Streptomyces venezuelae (see paper)
32% identity, 77% coverage of query (97.4 bits)
xdh / Q5UY95 D-xylose dehydrogenase subunit (EC 1.1.1.424) from Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809) (see paper)
GFO6_HALMA / Q5UY95 D-xylose 1-dehydrogenase [NADP(+)]; XDH; EC 1.1.1.424 from Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809) (Halobacterium marismortui) (see paper)
Q5UY95 D-xylose 1-dehydrogenase (NADP+, D-xylono-1,5-lactone-forming) (EC 1.1.1.179); D-xylose 1-dehydrogenase (NADP+, D-xylono-1,4-lactone-forming) (EC 1.1.1.424) from Haloarcula marismortui (see paper)
25% identity, 92% coverage of query (93.6 bits)
xacA / D4GP29 D-xylose dehydrogenase subunit (EC 1.1.1.424) from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (see 4 papers)
XDH1_HALVD / D4GP29 D-xylose 1-dehydrogenase [NADP(+)] 1; XDH 1; EC 1.1.1.424 from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii) (see 3 papers)
D4GP29 D-xylose 1-dehydrogenase (NADP+, D-xylono-1,5-lactone-forming) (EC 1.1.1.179); D-xylose 1-dehydrogenase (NADP+, D-xylono-1,4-lactone-forming) (EC 1.1.1.424) from Haloferax volcanii (see 2 papers)
27% identity, 91% coverage of query (87.4 bits)
1zh8A / Q9WYE8 Crystal structure of oxidoreductase (tm0312) from thermotoga maritima at 2.50 a resolution
27% identity, 77% coverage of query (73.2 bits)
D4GR07 L-arabinose 1-dehydrogenase [NAD(P)+] (EC 1.1.1.376) from Haloferax volcanii (see paper)
26% identity, 71% coverage of query (70.1 bits)
Q9EZV8 inositol 2-dehydrogenase (EC 1.1.1.18) from Sinorhizobium fredii (see paper)
29% identity, 77% coverage of query (69.7 bits)
4nheB / A0A0H2UR04 The crystal structure of oxidoreductase (gfo/idh/moca family) from streptococcus pneumoniae tigr4 in complex with NADP
24% identity, 84% coverage of query (67.8 bits)
6jw7A / Q6L737 The crystal structure of kand2 in complex with nadh and 3"-deamino-3"- hydroxykanamycin a (see paper)
25% identity, 77% coverage of query (58.5 bits)
6jw8A The crystal structure of kand2 in complex with nadh and 3"-deamino-3"- hydroxykanamycin b
25% identity, 77% coverage of query (58.5 bits)
6jw6A The crystal structure of kand2 in complex with NAD
25% identity, 77% coverage of query (58.5 bits)
CCNA_01702 predicted 3-ketohexose reductase from Caulobacter crescentus NA1000
23% identity, 90% coverage of query (54.3 bits)
Or start over
Lawrence Berkeley National Laboratory