Searching for up to 100 curated homologs for BPHYT_RS22015 FitnessBrowser__BFirm:BPHYT_RS22015 (363 a.a.)
Found high-coverage hits (≥70%) to 53 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
Q8YM92 ABC-type polyamine transporter (subunit 3/3) (EC 7.6.2.11) from Nostoc sp. PCC 7120 = FACHB-418 (see paper)
48% identity, 80% coverage of query (275 bits)
TC 3.A.1.20.1 / O54370 BitD, component of The iron transporter, BitABCDEF from Treponema hyodysenteriae (Serpulina hyodysenteriae) (see paper)
44% identity, 89% coverage of query (275 bits)
TC 3.A.1.11.7 / Q97Q42 Spermidine/putrescine import ATP-binding protein PotA, component of The spermidine/putrescine uptake porter, PotABCD from Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)
41% identity, 98% coverage of query (270 bits)
TC 3.A.1.20.3 / A3N296 Ferric ABC transporter ATP-binding protein, component of Iron (Fe3+) uptake porter, AfuABC (FbpABC) (Chin et al. 1996). AfuA has been characterized from Actinobacillus pleuropneumoniae serotype 5b (strain L20)
42% identity, 92% coverage of query (268 bits)
PotA / b1126 spermidine preferential ABC transporter ATP binding subunit (EC 7.6.2.11; EC 7.6.2.16) from Escherichia coli K-12 substr. MG1655 (see 5 papers)
PotA / P69874 spermidine preferential ABC transporter ATP binding subunit (EC 7.6.2.11) from Escherichia coli (strain K12) (see 5 papers)
POTA_ECOLI / P69874 Spermidine/putrescine import ATP-binding protein PotA; EC 7.6.2.11 from Escherichia coli (strain K12) (see 6 papers)
TC 3.A.1.11.1 / P69874 Spermidine/putrescine import ATP-binding protein PotA aka B1126, component of Polyamine (putrescine/spermidine) uptake porter from Escherichia coli (see 9 papers)
potA / MB|P69874 spermidine/putrescine ABC transporter, ATP-binding protein PotA; EC 3.6.3.31 from Escherichia coli K12 (see 10 papers)
48% identity, 80% coverage of query (268 bits)
UgpC / b3450 sn-glycerol 3-phosphate ABC transporter ATP binding subunit (EC 7.6.2.10) from Escherichia coli K-12 substr. MG1655 (see 5 papers)
UgpC / P10907 sn-glycerol 3-phosphate ABC transporter ATP binding subunit (EC 7.6.2.10) from Escherichia coli (strain K12) (see 2 papers)
UGPC_ECOLI / P10907 sn-glycerol-3-phosphate import ATP-binding protein UgpC; EC 7.6.2.10 from Escherichia coli (strain K12) (see 9 papers)
TC 3.A.1.1.3 / P10907 UgpC aka B3450, component of Glycerol-phosphate porter. Transports both glycerol-3-P and glycerol-3-P diesters including glycerophosphocholine but not glycerol-2-P from Escherichia coli (see 12 papers)
45% identity, 86% coverage of query (267 bits)
YagC / b0262 CP4-6 prophage; ABC transporter ATP-binding protein AfuC from Escherichia coli K-12 substr. MG1655 (see 4 papers)
46% identity, 81% coverage of query (267 bits)
mtlK / Q4KC54 polyol ABC-type transporterATP-binding component MtlK from Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5) (see paper)
43% identity, 90% coverage of query (266 bits)
TC 3.A.1.1.49 / O30494 MtlK, component of The polyol (mannitol, glucitol (sorbitol), arabitol (arabinitol; lyxitol)) uptake porter, MtlEFGK from Pseudomonas fluorescens
45% identity, 85% coverage of query (265 bits)
2d62A / O57933 Crystal structure of multiple sugar binding transport atp- binding protein
41% identity, 100% coverage of query (264 bits)
A0A142UTH4 ABC-type polyamine transporter (subunit 4/4) (EC 7.6.2.11) from Streptococcus suis (see paper)
44% identity, 86% coverage of query (263 bits)
Pf1N1B4_5115 sucrose ABC transporter, ATPase component from Pseudomonas fluorescens FW300-N1B4
42% identity, 90% coverage of query (262 bits)
PS417_12700 ABC transporter for D-Mannitol and D-Sorbitol, ATPase component from Pseudomonas simiae WCS417
44% identity, 85% coverage of query (261 bits)
1g291 / Q9YGA6 Malk (see paper)
42% identity, 99% coverage of query (261 bits)
BPHYT_RS16095 ABC transporter for D-Sorbitol, ATPase component from Burkholderia phytofirmans PsJN
42% identity, 87% coverage of query (259 bits)
MALK_THELN / Q9YGA6 Trehalose/maltose import ATP-binding protein MalK; EC 7.5.2.1 from Thermococcus litoralis (strain ATCC 51850 / DSM 5473 / JCM 8560 / NS-C) (see 5 papers)
42% identity, 99% coverage of query (258 bits)
TC 3.A.1.20.2 / Q9KLQ5 Fe(3+) ions import ATP-binding protein FbpC, component of Hexose-phosphate transporter from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
42% identity, 87% coverage of query (258 bits)
TC 3.A.1.1.12 / Q9AI63 PalK, component of Palatinose (isomaltulose; 6-O-α-D-glucopyranosyl-D-fructose) uptake porter from Erwinia rhapontici (see paper)
41% identity, 99% coverage of query (258 bits)
YdcT / b1441 putative ABC transporter ATP-binding protein YdcT from Escherichia coli K-12 substr. MG1655 (see 4 papers)
ydcT / P77795 putative ABC transporter ATP-binding protein YdcT from Escherichia coli (strain K12) (see 3 papers)
YDCT_ECOLI / P77795 Uncharacterized ABC transporter ATP-binding protein YdcT from Escherichia coli (strain K12) (see paper)
40% identity, 95% coverage of query (257 bits)
Pf6N2E2_1960 ABC transporter for D-sorbitol, ATPase component from Pseudomonas fluorescens FW300-N2E2
43% identity, 90% coverage of query (256 bits)
SM_b20002 ABC transporter for Lactose, ATPase component from Sinorhizobium meliloti 1021
44% identity, 82% coverage of query (256 bits)
MalK / b4035 maltose ABC transporter ATP binding subunit (EC 7.5.2.1) from Escherichia coli K-12 substr. MG1655 (see 31 papers)
MalK / P68187 maltose ABC transporter ATP binding subunit (EC 7.5.2.1) from Escherichia coli (strain K12) (see 29 papers)
MALK_ECOLI / P68187 Maltose/maltodextrin import ATP-binding protein MalK; EC 7.5.2.1 from Escherichia coli (strain K12) (see 6 papers)
P68187 ABC-type maltose transporter (subunit 3/3) (EC 7.5.2.1) from Escherichia coli (see paper)
TC 3.A.1.1.1 / P68187 Maltose/maltodextrin import ATP-binding protein MalK aka B4035, component of Maltooligosaccharide porter. The 3-D structure has been reported by Oldham et al. (2007). An altering access mechanism has been suggested for the maltose transporter resulting from rigid-body rotations (Khare et al., 2009). Bordignon et al. (2010) and Schneider et al. (2012) have reviewed the extensive knowledge available on MalEFGK2, its mode of action and its regulatory interactions from Escherichia coli (see 17 papers)
malK / RF|NP_418459 maltose/maltodextrin import ATP-binding protein malK; EC 3.6.3.19 from Escherichia coli K12 (see 18 papers)
44% identity, 80% coverage of query (254 bits)
PotG / b0855 putrescine ABC transporter ATP binding subunit (EC 7.6.2.11; EC 7.6.2.16) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
PotG / P31134 putrescine ABC transporter ATP binding subunit (EC 7.6.2.11) from Escherichia coli (strain K12) (see 2 papers)
POTG_ECOLI / P31134 Putrescine transport ATP-binding protein PotG; EC 7.6.2.16 from Escherichia coli (strain K12) (see 2 papers)
TC 3.A.1.11.2 / P31134 PotG aka B0855, component of Putrescine porter from Escherichia coli (see 4 papers)
41% identity, 90% coverage of query (254 bits)
TC 3.A.1.1.16 / Q8TZQ3 MalK aka PF1933, component of Maltooligosaccharide porter (Maltose is not a substrate, but maltotriose is.) from Pyrococcus furiosus
41% identity, 99% coverage of query (254 bits)
TC 3.A.1.11.6 / Q1M7Q1 Putative ABC transporter component, component of The γ-aminobutyrate (GABA) uptake system, GtsABCD from Rhizobium leguminosarum bv. viciae (strain 3841) (see paper)
41% identity, 96% coverage of query (254 bits)
AO356_00010 ABC transporter for D-Sorbitol, ATPase component from Pseudomonas fluorescens FW300-N2C3
43% identity, 90% coverage of query (254 bits)
Psest_0871 maltose ABC transporter, ATPase component MalK from Pseudomonas stutzeri RCH2
38% identity, 99% coverage of query (254 bits)
MALK_SALTY / P19566 Maltose/maltodextrin import ATP-binding protein MalK; EC 7.5.2.1 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
44% identity, 80% coverage of query (254 bits)
2awnB / P68187 Crystal structure of the adp-mg-bound e. Coli malk (crystallized with atp-mg) (see paper)
44% identity, 79% coverage of query (253 bits)
3puyA Crystal structure of an outward-facing mbp-maltose transporter complex bound to amp-pnp after crystal soaking of the pretranslocation state
44% identity, 79% coverage of query (253 bits)
3puxA Crystal structure of an outward-facing mbp-maltose transporter complex bound to adp-bef3
44% identity, 79% coverage of query (253 bits)
3puwA Crystal structure of an outward-facing mbp-maltose transporter complex bound to adp-alf4
44% identity, 79% coverage of query (253 bits)
3puvA Crystal structure of an outward-facing mbp-maltose transporter complex bound to adp-vo4
44% identity, 79% coverage of query (253 bits)
1q12A Crystal structure of the atp-bound e. Coli malk
44% identity, 79% coverage of query (253 bits)
TC 3.A.1.1.22 / Q9X103 MalK; aka Sugar ABC transporter, ATP-binding protein, component of The maltose, maltotriose, mannotetraose (MalE1)/maltose, maltotriose, trehalose (MalE2) porter (Nanavati et al., 2005). For MalG1 (823aas) and MalG2 (833aas), the C-terminal transmembrane domain with 6 putative TMSs is preceded by a single N-terminal TMS and a large (600 residue) hydrophilic region showing sequence similarity to MLP1 and 2 (9.A.14; e-12 & e-7) as well as other proteins from Thermotoga maritima (see paper)
46% identity, 82% coverage of query (252 bits)
Dshi_0546 ABC transporter for Xylitol, ATPase component from Dinoroseobacter shibae DFL-12
43% identity, 87% coverage of query (251 bits)
BWI76_RS01840 maltose ABC transporter, ATPase component (MalK) from Klebsiella michiganensis M5al
44% identity, 80% coverage of query (251 bits)
TC 3.A.1.1.4 / Q01937 LacK, component of Lactose porter from Agrobacterium radiobacter (see paper)
41% identity, 92% coverage of query (251 bits)
1vciA / O57758 Crystal structure of the atp-binding cassette of multisugar transporter from pyrococcus horikoshii ot3 complexed with atp (see paper)
40% identity, 99% coverage of query (249 bits)
8hprC Lpqy-sugabc in state 4
45% identity, 80% coverage of query (238 bits)
8hprD Lpqy-sugabc in state 4
45% identity, 80% coverage of query (238 bits)
8hplC / A0R2C0 Lpqy-sugabc in state 1 (see paper)
44% identity, 80% coverage of query (234 bits)
2awnC / P68187 Crystal structure of the adp-mg-bound e. Coli malk (crystallized with atp-mg) (see paper)
44% identity, 75% coverage of query (226 bits)
Q8TTZ3 ABC-type molybdate transporter (EC 7.3.2.5) from Methanosarcina acetivorans (see paper)
3d31A / Q8TTZ3 Modbc from methanosarcina acetivorans (see paper)
36% identity, 83% coverage of query (201 bits)
2awnA / P68187 Crystal structure of the adp-mg-bound e. Coli malk (crystallized with atp-mg) (see paper)
38% identity, 79% coverage of query (184 bits)
3fvqB / Q5FA19 Crystal structure of the nucleotide binding domain fbpc complexed with atp (see paper)
38% identity, 80% coverage of query (170 bits)
Build an alignment for BPHYT_RS22015 and 46 homologs with ≥ 30% identity
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5lilA / Q2EHL8 Structure of aggregatibacter actinomycetemcomitans macb bound to atpys (p21) (see paper)
28% identity, 77% coverage of query (114 bits)
5lj7A / Q2EHL8 Structure of aggregatibacter actinomycetemcomitans macb bound to atp (p21) (see paper)
28% identity, 77% coverage of query (114 bits)
3gd7A / P13569,P68187 Crystal structure of human nbd2 complexed with n6-phenylethyl-atp (p- atp)
28% identity, 79% coverage of query (107 bits)
8bmpB / Q1GBI9 Cryo-em structure of the folate-specific ecf transporter complex in msp2n2 lipid nanodiscs bound to atp and adp (see paper)
30% identity, 71% coverage of query (97.4 bits)
5d3mB Folate ecf transporter: amppnp bound state
30% identity, 71% coverage of query (97.4 bits)
8bmsB Cryo-em structure of the mutant solitary ecf module 2eq in msp2n2 lipid nanodiscs in the atpase closed and atp-bound conformation
29% identity, 71% coverage of query (96.3 bits)
8i3aA / Q84TH5 Cryo-em structure of abscisic acid transporter atabcg25 in outward conformation (see paper)
26% identity, 74% coverage of query (89.0 bits)
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Lawrence Berkeley National Laboratory