Searching for up to 100 curated homologs for BPHYT_RS22155 FitnessBrowser__BFirm:BPHYT_RS22155 (291 a.a.)
Found high-coverage hits (≥70%) to 75 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
davA / Q88QV2 5-aminopentanamidase (EC 3.5.1.30) from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440) (see paper)
Q88QV2 5-aminopentanamidase (EC 3.5.1.30) from Pseudomonas putida (see paper)
33% identity, 81% coverage of query (115 bits)
Pf1N1B4_2504 5-aminopentanamidase (EC 3.5.1.30) from Pseudomonas fluorescens FW300-N1B4
33% identity, 88% coverage of query (115 bits)
B3IVI7 5-aminopentanamidase (EC 3.5.1.30) from Pseudomonas putida (see 4 papers)
33% identity, 81% coverage of query (115 bits)
AO353_07425 5-aminopentanamidase (EC 3.5.1.30) from Pseudomonas fluorescens FW300-N2E3
32% identity, 88% coverage of query (113 bits)
PfGW456L13_1170 5-aminopentanamidase (EC 3.5.1.30) from Pseudomonas fluorescens GW456-L13
32% identity, 88% coverage of query (111 bits)
Pf6N2E2_4777 5-aminopentanamidase (EC 3.5.1.30) from Pseudomonas fluorescens FW300-N2E2
31% identity, 88% coverage of query (99.8 bits)
Build an alignment for BPHYT_RS22155 and 6 homologs with ≥ 30% identity
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F8AEP0 amidase (EC 3.5.1.4) from Pyrococcus yayanosii (see paper)
28% identity, 86% coverage of query (99.0 bits)
AO356_14225 5-aminopentanamidase (EC 3.5.1.30) from Pseudomonas fluorescens FW300-N2C3
30% identity, 88% coverage of query (97.8 bits)
4iztA / D0VWZ1 The e41q mutant of the amidase from nesterenkonia sp. An1 showing covalent addition of the acetamide moiety of fluoroacetamide at the active site cysteine
33% identity, 87% coverage of query (92.4 bits)
C6K3Z5 amidase (EC 3.5.1.4) from Nesterenkonia sp. (see paper)
34% identity, 82% coverage of query (90.9 bits)
SGR_6069 / B1W481 4-guanidinobutanamidase (EC 3.5.1.4) from Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350) (see 2 papers)
35% identity, 89% coverage of query (90.1 bits)
5nybA A c145a mutant of nesterenkonia an1 amidase bound to adipamide
33% identity, 87% coverage of query (90.1 bits)
5ny7A A c145a mutant of nesterenkonia an1 amidase bound to nicotinamide
33% identity, 87% coverage of query (90.1 bits)
4izuA The e41q mutant of the amidase from nesterenkonia sp. An1 showing the result of michael addition of acrylamide at the active site cysteine
34% identity, 79% coverage of query (88.6 bits)
3klcA / Q9UYV8 Crystal structure of hyperthermophilic nitrilase (see paper)
26% identity, 85% coverage of query (87.4 bits)
3klcB Crystal structure of hyperthermophilic nitrilase
26% identity, 85% coverage of query (87.4 bits)
NITR_PYRAB / Q9UYV8 Nitrilase; PaNit; EC 3.5.5.1 from Pyrococcus abyssi (strain GE5 / Orsay) (see 2 papers)
26% identity, 85% coverage of query (86.7 bits)
5nycA A c145a mutant of nesterenkonia an1 amidase bound to propionitrile
34% identity, 81% coverage of query (86.7 bits)
4izsA The c145a mutant of the amidase from nesterenkonia sp. An1 in complex with butyramide
34% identity, 81% coverage of query (86.7 bits)
NIT2_HUMAN / Q9NQR4 Omega-amidase NIT2; Nitrilase homolog 2; EC 3.5.1.3 from Homo sapiens (Human) (see 4 papers)
Q9NQR4 omega-amidase (EC 3.5.1.3) from Homo sapiens (see paper)
27% identity, 93% coverage of query (86.3 bits)
ramA / Q75SP7 (R)-amidase (EC 3.5.1.100) from Pseudomonas sp. (see paper)
RSAM_PSESP / Q75SP7 (R)-stereoselective amidase; EC 3.5.1.100 from Pseudomonas sp. (see paper)
Q75SP7 (R)-amidase (EC 3.5.1.100) from Pseudomonas sp. (see paper)
31% identity, 79% coverage of query (86.3 bits)
A0A088BHP3 aryl-acylamidase (EC 3.5.1.13); amidase (EC 3.5.1.4) from Streptomyces sp. (see paper)
27% identity, 88% coverage of query (85.5 bits)
YCU9_SCHPO / O59829 Probable nitrilase C965.09; EC 3.5.-.- from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
26% identity, 82% coverage of query (82.8 bits)
NIT3_YEAST / P49954 Omega-amidase NIT3; Nitrilase homolog 2; EC 3.5.1.3 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 3 papers)
24% identity, 85% coverage of query (81.6 bits)
6ypaB / O58376 The c146a variant of an amidase from pyrococcus horikoshii with bound glutaramide
26% identity, 93% coverage of query (81.3 bits)
7ovgA The c146a variant of an amidase from pyrococcus horikoshii with bound acetamide
25% identity, 91% coverage of query (79.7 bits)
D2SGH7 nitrilase (EC 3.5.5.1) from Geodermatophilus obscurus (see paper)
29% identity, 88% coverage of query (79.3 bits)
NIT2_RAT / Q497B0 Omega-amidase NIT2; Nitrilase homolog 2; EC 3.5.1.3 from Rattus norvegicus (Rat) (see 2 papers)
26% identity, 89% coverage of query (79.0 bits)
Nit2 / Q9JHW2 ω-amidase NIT2 monomer (EC 3.5.1.3) from Mus musculus (see 2 papers)
NIT2_MOUSE / Q9JHW2 Omega-amidase NIT2; Nitrilase homolog 2; EC 3.5.1.3 from Mus musculus (Mouse) (see 3 papers)
26% identity, 89% coverage of query (77.4 bits)
B8A0E5 omega-amidase (EC 3.5.1.3) from Zea mays (see paper)
27% identity, 86% coverage of query (76.6 bits)
B8A2V8 omega-amidase (EC 3.5.1.3) from Zea mays (see paper)
26% identity, 87% coverage of query (76.3 bits)
A0A0E3D8K7 nitrilase (EC 3.5.5.1); Aliphatic nitrilase (EC 3.5.5.7) from Fusarium proliferatum (see paper)
26% identity, 87% coverage of query (73.9 bits)
NILP3_ARATH / Q8RUF8 Omega-amidase, chloroplastic; Nitrilase-like protein 3; EC 3.5.1.3 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
Q8RUF8 omega-amidase (EC 3.5.1.3) from Arabidopsis thaliana (see paper)
27% identity, 90% coverage of query (72.8 bits)
A0QQY9 D-inositol-3-phosphate glycosyltransferase (EC 2.4.1.250) from Mycolicibacterium smegmatis (see paper)
31% identity, 87% coverage of query (69.3 bits)
A0A023XI92 N-carbamoyl-D-amino-acid hydrolase (EC 3.5.1.77) from Bradyrhizobium japonicum (see paper)
24% identity, 81% coverage of query (66.2 bits)
mtnU / O31664 2-oxoglutaramate:glutamine aminotransferase (EC 3.5.1.3) from Bacillus subtilis (strain 168) (see 4 papers)
MTNU_BACSU / O31664 2-oxoglutaramate amidase; EC 3.5.1.111 from Bacillus subtilis (strain 168) (see 2 papers)
24% identity, 88% coverage of query (65.9 bits)
Q9HVU6 deaminated glutathione amidase (EC 3.5.1.128) from Pseudomonas aeruginosa (see paper)
28% identity, 84% coverage of query (64.3 bits)
NILP2_ARATH / Q94JV5 Deaminated glutathione amidase, chloroplastic/cytosolic; dGSH amidase; Nitrilase-like protein 2; Protein nitrilase 1 homolog; AtNit1; Protein Nit1 homolog; EC 3.5.1.128 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
Q94JV5 deaminated glutathione amidase (EC 3.5.1.128) from Arabidopsis thaliana (see paper)
26% identity, 86% coverage of query (63.9 bits)
YHCX_BACSU / P54608 Probable hydrolase YhcX; EC 3.5.-.- from Bacillus subtilis (strain 168) (see paper)
24% identity, 84% coverage of query (63.9 bits)
NADE_ACIAD / Q6F8K4 Glutamine-dependent NAD(+) synthetase; NAD synthetase; NAD(+) synthase [glutamine-hydrolyzing]; EC 6.3.5.1 from Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1) (see paper)
24% identity, 82% coverage of query (63.5 bits)
Q44185 N-carbamoyl-D-amino acid hydrolase; D-N-alpha-carbamilase; EC 3.5.1.77 from Rhizobium radiobacter (Agrobacterium tumefaciens) (Agrobacterium radiobacter)
24% identity, 90% coverage of query (61.6 bits)
Q84FR7 N-carbamoyl-D-amino-acid hydrolase (EC 3.5.1.77) from Arthrobacter crystallopoietes (see paper)
25% identity, 76% coverage of query (60.8 bits)
NIT1_SYNYG / P0DP66 Deaminated glutathione amidase; dGSH amidase; Nitrilase homolog 1; syNit1; EC 3.5.1.128 from Synechocystis sp. (strain PCC 6803 / GT-S) (see paper)
P0DP66 deaminated glutathione amidase (EC 3.5.1.128) from Synechocystis sp. PCC 6803 (see paper)
26% identity, 85% coverage of query (60.5 bits)
YAFV_STAA4 / P0DP65 Omega-amidase YafV; saYafV; EC 3.5.1.3 from Staphylococcus aureus (strain 04-02981) (see paper)
23% identity, 86% coverage of query (59.3 bits)
A3DHT2 nitrilase (EC 3.5.5.1) from Acetivibrio thermocellus (see paper)
24% identity, 83% coverage of query (58.5 bits)
YafV / b0219 2-oxoglutaramate amidase (EC 3.5.1.3; EC 3.5.1.111) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
yafV / Q47679 2-oxoglutaramate amidase (EC 3.5.1.3) from Escherichia coli (strain K12) (see paper)
26% identity, 75% coverage of query (58.5 bits)
YAFV_ECOBD / A0A140NDS5 Omega-amidase YafV; ecYafV; EC 3.5.1.3 from Escherichia coli (strain B / BL21-DE3) (see paper)
26% identity, 75% coverage of query (57.8 bits)
A3QYW3 nitrilase (EC 3.5.5.1) from Brassica rapa (see paper)
23% identity, 86% coverage of query (57.0 bits)
8hpcC / P60327 Crystal structure of c171a mutant of n-carbamyl-d-amino acid amidohydrolase complexed with n-carbamyl-d-hydroxyphenylglycine
24% identity, 90% coverage of query (57.0 bits)
B0V8W9 NAD+ synthase (glutamine-hydrolysing) (EC 6.3.5.1) from Acinetobacter baumannii (see paper)
23% identity, 82% coverage of query (57.0 bits)
5khaA / V5VHL3 Structure of glutamine-dependent NAD+ synthetase from acinetobacter baumannii in complex with adenosine diphosphate (adp)
23% identity, 82% coverage of query (56.6 bits)
pydC / Q846U4 3-amino-isobutyrate synthase (EC 3.5.1.6) from Brevibacillus agri (see paper)
24% identity, 82% coverage of query (56.2 bits)
aguB / Q9I6J8 N-carbamoylputrascine amidohydrolase subunit (EC 3.5.1.53) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
24% identity, 87% coverage of query (55.8 bits)
ORF77 / Q93NG1 2-ketoglutaramate amidase monomer (EC 3.5.1.3) from Paenarthrobacter nicotinovorans (see 2 papers)
NIT_PAENI / Q93NG1 2-oxoglutaramate amidase; Omega-amidase; EC 3.5.1.111 from Paenarthrobacter nicotinovorans (Arthrobacter nicotinovorans) (see paper)
Q93NG1 2-oxoglutaramate amidase (EC 3.5.1.111) from Paenarthrobacter nicotinovorans (see paper)
23% identity, 92% coverage of query (55.5 bits)
1uf8A Crystal structure of c171a/v236a mutant of n-carbamyl-d-amino acid amidohydrolase complexed with n-carbamyl-d-phenylalanine
24% identity, 90% coverage of query (55.5 bits)
1uf7A Crystal structure of c171a/v236a mutant of n-carbamyl-d-amino acid amidohydrolase complexed with n-carbamyl-d-valine
24% identity, 90% coverage of query (55.5 bits)
1uf5A Crystal structure of c171a/v236a mutant of n-carbamyl-d-amino acid amidohydrolase complexed with n-carbamyl-d-methionine
24% identity, 90% coverage of query (55.5 bits)
4hg3A / P47016 Structural insights into yeast nit2: wild-type yeast nit2 in complex with alpha-ketoglutarate (see paper)
23% identity, 90% coverage of query (54.7 bits)
NIT2_YEAST / P47016 Deaminated glutathione amidase; dGSH amidase; Nitrilase homolog 1; EC 3.5.1.128 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 2 papers)
P47016 deaminated glutathione amidase (EC 3.5.1.128) from Saccharomyces cerevisiae (see paper)
23% identity, 90% coverage of query (54.7 bits)
4hg5A Structural insights into yeast nit2: wild-type yeast nit2 in complex with oxaloacetate
23% identity, 90% coverage of query (54.7 bits)
DCAS_ENSAD / Q5S260 N-carbamoyl-D-amino acid hydrolase; D-carbamoylase; EC 3.5.1.77 from Ensifer adhaerens (Sinorhizobium morelense) (see paper)
Q5S260 N-carbamoyl-D-amino-acid hydrolase (EC 3.5.1.77) from Ensifer adhaerens (see paper)
23% identity, 90% coverage of query (54.3 bits)
W6R265 cyanoalanine nitrilase (EC 3.5.5.4) from Pseudomonas oleovorans (see paper)
22% identity, 84% coverage of query (53.1 bits)
YBEM_ECOBD / A0A140NCB4 Deaminated glutathione amidase; dGSH amidase; Nitrilase homolog 1; ecYbeM; EC 3.5.1.128 from Escherichia coli (strain B / BL21-DE3) (see paper)
28% identity, 80% coverage of query (52.8 bits)
NIT1_YEREN / P0DP68 Deaminated glutathione amidase; dGSH amidase; Nitrilase homolog 1; yeNit1; EC 3.5.1.128 from Yersinia enterocolitica (see paper)
P0DP68 deaminated glutathione amidase (EC 3.5.1.128) from Yersinia enterocolitica (see paper)
26% identity, 75% coverage of query (52.0 bits)
NIT4A / Q5QGZ8 β-cyano-L-alanine nitrilase (EC 3.5.5.4; EC 4.2.1.65) from Lupinus angustifolius (see paper)
NRL4A_LUPAN / Q5QGZ8 Bifunctional nitrilase/nitrile hydratase NIT4A; LaNIT4A; 3-cyanoalanine hydratase; Cyanoalanine nitrilase A; EC 3.5.5.4; EC 4.2.1.65 from Lupinus angustifolius (Narrow-leaved blue lupine) (see paper)
Q5QGZ8 cyanoalanine nitrilase (EC 3.5.5.4); 3-Cyanoalanine hydratase (EC 4.2.1.65) from Lupinus angustifolius (see paper)
24% identity, 82% coverage of query (51.2 bits)
NFT1_CAEEL / O76463 Nitrilase and fragile histidine triad fusion protein NitFhit; EC 3.6.1.29; EC 3.5.-.- from Caenorhabditis elegans (see 2 papers)
23% identity, 91% coverage of query (50.4 bits)
NIT3 / P46010 Nit3 (EC 3.5.5.1; EC 4.2.1.84) from Arabidopsis thaliana (see 4 papers)
P46010 nitrilase (EC 3.5.5.1) from Arabidopsis thaliana (see 2 papers)
22% identity, 84% coverage of query (50.4 bits)
NIT1 / P32961 Nit1 (EC 3.5.5.1; EC 4.2.1.84) from Arabidopsis thaliana (see 5 papers)
NRL1_ARATH / P32961 Nitrilase 1; EC 3.5.5.1 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
P32961 deaminated glutathione amidase (EC 3.5.1.128); nitrilase (EC 3.5.5.1) from Arabidopsis thaliana (see 6 papers)
20% identity, 85% coverage of query (50.4 bits)
NIT2_PENRW / B6HVR6 Nitrilase; NitPc2; EC 3.5.5.1 from Penicillium rubens (strain ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin 54-1255) (Penicillium chrysogenum) (see paper)
22% identity, 82% coverage of query (50.4 bits)
4hgdA Structural insights into yeast nit2: c169s mutant of yeast nit2 in complex with an endogenous peptide-like ligand
23% identity, 88% coverage of query (50.4 bits)
NFT1_DROME / O76464 Nitrilase and fragile histidine triad fusion protein NitFhit; NFT-1 protein; EC 3.6.1.29; EC 3.5.-.- from Drosophila melanogaster (Fruit fly) (see paper)
23% identity, 95% coverage of query (49.3 bits)
NIT1_MOUSE / Q8VDK1 Deaminated glutathione amidase; dGSH amidase; Nitrilase homolog 1; EC 3.5.1.128 from Mus musculus (Mouse) (see 7 papers)
Q8VDK1 deaminated glutathione amidase (EC 3.5.1.128) from Mus musculus (see paper)
25% identity, 79% coverage of query (48.5 bits)
R0H4W3 nitrilase (EC 3.5.5.1) from Capsella rubella (see paper)
22% identity, 88% coverage of query (47.0 bits)
YAFV_YEREN / P0DP67 Omega-amidase YafV; yeYafV; EC 3.5.1.3 from Yersinia enterocolitica (see paper)
25% identity, 74% coverage of query (45.4 bits)
NRL4_ARATH / P46011 Bifunctional nitrilase/nitrile hydratase NIT4; Cyanoalanine nitrilase; Nitrilase 4; EC 3.5.5.1; EC 3.5.5.4; EC 4.2.1.65 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
23% identity, 82% coverage of query (45.1 bits)
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Lawrence Berkeley National Laboratory