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Searching for up to 100 curated homologs for BPHYT_RS22245 FitnessBrowser__BFirm:BPHYT_RS22245 (493 a.a.)

Found high-coverage hits (≥70%) to 9 curated proteins.

Removed hits that are identical to the query, leaving 8

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

MCTP_RHIJ3 / Q1M7A2 Monocarboxylate transport permease protein from Rhizobium johnstonii (strain DSM 114642 / LMG 32736 / 3841) (Rhizobium leguminosarum bv. viciae) (see paper)
    66% identity, 94% coverage of query (551 bits)

TC 2.A.21.4.1 / Q8VM88 The monocarboxylate uptake (H+ symport?) permease, MctP (transports lactate (Km = 4.4 μM), pyruvate (Km = 3.8), propionate, butyrate (butanoic acid), α-hydroxybutyrate, L- and D-alanine (Km = 0.5 mM), and possibly cysteine and histidine) from Rhizobium leguminosarum (biovar viciae) (see paper)
mctP / CAD19128.1 monocarboxylic acid permease from Rhizobium leguminosarum bv. viciae (see paper)
    66% identity, 94% coverage of query (548 bits)

Build an alignment

Build an alignment for BPHYT_RS22245 and 2 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

SC5A7_CAEEL / O02228 High-affinity choline transporter 1 from Caenorhabditis elegans (see paper)
    23% identity, 86% coverage of query (63.2 bits)

Pf6N2E2_5849 large component of pyruvate transporter (actP-like) from Pseudomonas fluorescens FW300-N2E2
    22% identity, 89% coverage of query (50.8 bits)

PS417_08865 large component of pyruvate transporter (actP-like) from Pseudomonas simiae WCS417
    22% identity, 93% coverage of query (50.1 bits)

PUTP_STAA8 / Q2FWY7 Sodium/proline symporter; Proline permease from Staphylococcus aureus (strain NCTC 8325 / PS 47) (see 3 papers)
TC 2.A.21.2.2 / Q7A4Q7 Sodium/proline symporter (Proline permease) from Staphylococcus aureus (strain N315) (see paper)
    22% identity, 95% coverage of query (49.7 bits)

Pf1N1B4_3673 large component of pyruvate transporter (actP-like) from Pseudomonas fluorescens FW300-N1B4
    22% identity, 89% coverage of query (48.9 bits)

YjcG / b4067 acetate/glycolate:cation symporter from Escherichia coli K-12 substr. MG1655 (see 2 papers)
actP / P32705 acetate/glycolate:cation symporter from Escherichia coli (strain K12) (see 5 papers)
ACTP_ECOLI / P32705 Cation/acetate symporter ActP; Acetate permease; Acetate transporter ActP from Escherichia coli (strain K12) (see 2 papers)
TC 2.A.21.7.2 / P32705 Acetate/glyoxylate permease, ActP from Escherichia coli (see 6 papers)
    23% identity, 88% coverage of query (47.8 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory