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Searching for up to 100 curated homologs for BPHYT_RS25805 FitnessBrowser__BFirm:BPHYT_RS25805 (328 a.a.)

Found high-coverage hits (≥70%) to 100 curated proteins.

Removed hits that are identical to the query, leaving 99

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

H281DRAFT_01116 deoxyribose kinase (EC 2.7.1.15) from Paraburkholderia bryophila 376MFSha3.1
    85% identity, 97% coverage of query (503 bits)

deoK / Q8XGW5 deoxyribokinase monomer (EC 2.7.1.229) from Salmonella typhi (see 4 papers)
    37% identity, 92% coverage of query (199 bits)

AO356_00950 Ribokinase (EC 2.7.1.15) from Pseudomonas fluorescens FW300-N2C3
    43% identity, 91% coverage of query (198 bits)

BT2803 ribokinase (EC 2.7.1.15) from Bacteroides thetaiotaomicron VPI-5482
    37% identity, 91% coverage of query (194 bits)

AO353_20835 Ribokinase (EC 2.7.1.15) from Pseudomonas fluorescens FW300-N2E3
    44% identity, 91% coverage of query (193 bits)

Pf1N1B4_6031 Ribokinase (EC 2.7.1.15) from Pseudomonas fluorescens FW300-N1B4
    44% identity, 91% coverage of query (191 bits)

BWI76_RS00290 Ribokinase (EC 2.7.1.15) from Klebsiella michiganensis M5al
    40% identity, 93% coverage of query (182 bits)

RBSK_SCHPO / O60116 Ribokinase; RK; EC 2.7.1.15 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
    39% identity, 92% coverage of query (178 bits)

RBSK_STAAC / A0A0H2WZY4 Ribokinase; RK; EC 2.7.1.15 from Staphylococcus aureus (strain COL) (see paper)
A0A0H2WZY4 ribokinase (EC 2.7.1.15) from Staphylococcus aureus (see paper)
    38% identity, 92% coverage of query (176 bits)

RbsK / b3752 ribokinase (EC 2.7.1.15) from Escherichia coli K-12 substr. MG1655 (see 20 papers)
rbsK / P0A9J6 ribokinase (EC 2.7.1.15) from Escherichia coli (strain K12) (see 19 papers)
RBSK_ECOLI / P0A9J6 Ribokinase; RK; EC 2.7.1.15 from Escherichia coli (strain K12) (see 5 papers)
rbsK / RF|NP_418208 ribokinase from Escherichia coli K12 (see 4 papers)
    39% identity, 94% coverage of query (175 bits)

1gqtB / P0A9J6 Activation of ribokinase by monovalent cations (see paper)
    39% identity, 93% coverage of query (175 bits)

4xckA / A0A0H2UL04 Vibrio cholerae o395 ribokinase complexed with adp, ribose and cesium ion. (see paper)
    39% identity, 93% coverage of query (174 bits)

A0A0H2UL04 ribokinase (EC 2.7.1.15) from Vibrio cholerae (see paper)
    39% identity, 93% coverage of query (174 bits)

1rk2A E. Coli ribokinase complexed with ribose and adp, solved in space group p212121
    39% identity, 93% coverage of query (174 bits)

BT2804 ribokinase (EC 2.7.1.15) from Bacteroides thetaiotaomicron VPI-5482
    36% identity, 92% coverage of query (165 bits)

RBSKI_FRUSL / P83534 Bifunctional ribokinase/ribose-5-phosphate isomerase A; EC 2.7.1.15; EC 5.3.1.6 from Fructilactobacillus sanfranciscensis (strain ATCC 27651 / DSM 20451 / JCM 5668 / CCUG 30143 / KCTC 3205 / NCIMB 702811 / NRRL B-3934 / L-12) (Lactobacillus sanfranciscensis) (see paper)
    34% identity, 92% coverage of query (161 bits)

HSERO_RS11500 Ribokinase (EC 2.7.1.15) from Herbaspirillum seropedicae SmR1
    40% identity, 90% coverage of query (161 bits)

2fv7A Crystal structure of human ribokinase
    38% identity, 89% coverage of query (160 bits)

5c3yA Structure of human ribokinase crystallized with amppnp
    38% identity, 89% coverage of query (160 bits)

5c41A / Q9H477 Crystal structure of human ribokinase in complex with amppcp in p21 spacegroup and with 4 protomers
    38% identity, 89% coverage of query (159 bits)

6wk0B Crystal structure of human ribokinase in complex with amppcp and ribose
    38% identity, 89% coverage of query (159 bits)

6wjzA Crystal structure of human ribokinase in complex with ampcp
    38% identity, 89% coverage of query (159 bits)

RBSK_HUMAN / Q9H477 Ribokinase; RK; EC 2.7.1.15 from Homo sapiens (Human) (see paper)
Q9H477 ribokinase (EC 2.7.1.15) from Homo sapiens (see paper)
    38% identity, 88% coverage of query (155 bits)

5byfA Crystal structure of human ribokinase in complex with amp
    38% identity, 88% coverage of query (155 bits)

8cqxA / A0A0B0SD75 Ribokinase from t.Sp mutant a92g
    36% identity, 91% coverage of query (149 bits)

RBSK_LEIMA / E9AD19 Ribokinase; RK; EC 2.7.1.15 from Leishmania major (see paper)
    34% identity, 90% coverage of query (139 bits)

6a8aA / A0A3S7X0F5 Ribokinase from leishmania donovani with atp (see paper)
    35% identity, 90% coverage of query (139 bits)

6a8cA Ribokinase from leishmania donovani with adp
    35% identity, 90% coverage of query (139 bits)

6a8bA Ribokinase from leishmania donovani with amppcp
    35% identity, 90% coverage of query (139 bits)

SMc01103 Ribokinase (EC 2.7.1.15) from Sinorhizobium meliloti 1021
    33% identity, 90% coverage of query (127 bits)

6znxC / A0A0B0SD75 Ribokinase from thermus species
    34% identity, 83% coverage of query (117 bits)

Q8NQR0 ribokinase (EC 2.7.1.15) from Corynebacterium glutamicum (see paper)
    34% identity, 89% coverage of query (117 bits)

Build an alignment

Build an alignment for BPHYT_RS25805 and 32 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

RBSK / A1A6H3 ribokinase (EC 2.7.1.15) from Arabidopsis thaliana (see 2 papers)
RBSK_ARATH / A1A6H3 Ribokinase; AtRBSK; RK; EC 2.7.1.15 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
A1A6H3 ribokinase (EC 2.7.1.15) from Arabidopsis thaliana (see paper)
    29% identity, 92% coverage of query (112 bits)

6ilsB / A1A6H3 Structure of arabidopsis thaliana ribokinase complexed with ribose and atp (see paper)
    29% identity, 92% coverage of query (112 bits)

RBSK_YEAST / P25332 Ribokinase; RK; EC 2.7.1.15 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 2 papers)
    27% identity, 91% coverage of query (108 bits)

3ikhA / A6T989 Crystal structure of ribokinase in complex with atp and glycerol in the active site from klebsiella pneumoniae
    31% identity, 80% coverage of query (95.5 bits)

3i3yD Crystal structure of ribokinase in complex with d-ribose from klebsiella pneumoniae
    31% identity, 80% coverage of query (95.5 bits)

Q9YG89 6-phosphofructokinase (EC 2.7.1.11) from Aeropyrum pernix (see 2 papers)
    31% identity, 90% coverage of query (92.0 bits)

YdjH / b1772 L-glycero-L-galacto-octuluronate kinase from Escherichia coli K-12 substr. MG1655 (see 2 papers)
ydjH / P77493 L-glycero-L-galacto-octuluronate kinase from Escherichia coli (strain K12) (see 2 papers)
    28% identity, 83% coverage of query (82.4 bits)

3in1A / P77493 Crystal structure of a putative ribokinase in complex with adp from e.Coli
    28% identity, 83% coverage of query (82.0 bits)

Q42896 fructokinase (EC 2.7.1.4) from Solanum lycopersicum (see paper)
    25% identity, 83% coverage of query (80.1 bits)

6xk2A / J9VQ51 Crystal structure of ribokinase from cryptococcus neoformans var. Grubii serotype a in complex with adp
    28% identity, 92% coverage of query (79.7 bits)

P37829 fructokinase (EC 2.7.1.4) from Solanum tuberosum (see 2 papers)
    26% identity, 83% coverage of query (79.3 bits)

SCRK1_MAIZE / Q6XZ79 Fructokinase-1; ZmFRK1; EC 2.7.1.4 from Zea mays (Maize)
    25% identity, 84% coverage of query (79.0 bits)

RR42_RS28860 2-dehydro-3-deoxygluconokinase (EC 2.7.1.45) from Cupriavidus basilensis FW507-4G11
    30% identity, 81% coverage of query (77.4 bits)

Q9M1B9 fructokinase (EC 2.7.1.4) from Arabidopsis thaliana (see paper)
    25% identity, 83% coverage of query (75.5 bits)

SCRK2_ORYSI / A2YQL4 Fructokinase-2; Fructokinase II; OsFKII; EC 2.7.1.4 from Oryza sativa subsp. indica (Rice) (see paper)
SCRK2_ORYSJ / Q0J8G4 Fructokinase-2; Fructokinase II; OsFKII; EC 2.7.1.4 from Oryza sativa subsp. japonica (Rice) (see 2 papers)
A2YQL4 fructokinase (EC 2.7.1.4) from Oryza sativa (see paper)
    24% identity, 83% coverage of query (75.5 bits)

SCRK1_ORYSJ / Q0JGZ6 Fructokinase-1; Fructokinase I; OsFKI; EC 2.7.1.4 from Oryza sativa subsp. japonica (Rice) (see paper)
    25% identity, 83% coverage of query (74.3 bits)

SCRK1_ORYSI / A2WXV8 Fructokinase-1; Fructokinase I; OsFKI; EC 2.7.1.4 from Oryza sativa subsp. indica (Rice) (see paper)
    25% identity, 83% coverage of query (74.3 bits)

O82616 fructokinase (EC 2.7.1.4) from Arabidopsis thaliana (see paper)
    24% identity, 85% coverage of query (73.2 bits)

Q9SID0 fructokinase (EC 2.7.1.4) from Arabidopsis thaliana (see paper)
    24% identity, 83% coverage of query (71.6 bits)

Q42645 fructokinase (EC 2.7.1.4) from Beta vulgaris (see paper)
    24% identity, 83% coverage of query (70.9 bits)

O04897 fructokinase (EC 2.7.1.4) from Solanum lycopersicum (see paper)
    25% identity, 83% coverage of query (70.5 bits)

3iq0B / A0A0H2VDX9 Crystal structure of a putative ribokinase ii in complex with atp and mg+2 from e.Coli
    27% identity, 78% coverage of query (70.1 bits)

Q9LNE4 fructokinase (EC 2.7.1.4) from Arabidopsis thaliana (see paper)
    24% identity, 80% coverage of query (70.1 bits)

7aghA Crystal structure of sf kinase yihv from e. Coli in complex with amppnp-mg
    29% identity, 92% coverage of query (69.7 bits)

SquV / b3883 6-deoxy-6-sulfofructose kinase (EC 2.7.1.184) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
yihV / P32143 6-deoxy-6-sulfofructose kinase (EC 2.7.1.184) from Escherichia coli (strain K12) (see 2 papers)
SQUV_ECOLI / P32143 Sulfofructose kinase; SF kinase; EC 2.7.1.184 from Escherichia coli (strain K12) (see 2 papers)
    29% identity, 92% coverage of query (69.3 bits)

7agkA Crystal structure of e. Coli sf kinase (yihv) in complex with product sulfofructose phosphate (sfp)
    29% identity, 92% coverage of query (69.3 bits)

7ag6A / P32143 Crystal structure of sf kinase yihv from e. Coli in complex with sulfofructose (sf), adp-mg (see paper)
    29% identity, 92% coverage of query (68.9 bits)

Q9FLH8 fructokinase (EC 2.7.1.4) from Arabidopsis thaliana (see 2 papers)
    24% identity, 83% coverage of query (67.0 bits)

KDGK_BACSU / P50845 2-dehydro-3-deoxygluconokinase; 2-keto-3-deoxygluconokinase; 3-deoxy-2-oxo-D-gluconate kinase; KDG kinase; EC 2.7.1.45 from Bacillus subtilis (strain 168) (see paper)
    25% identity, 87% coverage of query (66.2 bits)

SCRK2_MAIZE / Q6XZ78 Fructokinase-2; ZmFRK2; EC 2.7.1.4 from Zea mays (Maize)
    24% identity, 80% coverage of query (65.9 bits)

P71913 ribokinase (EC 2.7.1.15) from Mycobacterium tuberculosis (see paper)
    33% identity, 84% coverage of query (65.9 bits)

3go6A / P71913 Crystal structure of m. Tuberculosis ribokinase (rv2436) in complex with ribose and amp-pnp
    33% identity, 84% coverage of query (65.5 bits)

3go6B Crystal structure of m. Tuberculosis ribokinase (rv2436) in complex with ribose and amp-pnp
    33% identity, 84% coverage of query (65.5 bits)

7c1zA Atp bound structure of pseudouridine kinase (puki) from arabidopsis thaliana
    26% identity, 90% coverage of query (64.7 bits)

Echvi_2804 Fructokinase (EC 2.7.1.4) from Echinicola vietnamensis KMM 6221, DSM 17526
    24% identity, 79% coverage of query (63.2 bits)

2c49A / Q57849 Crystal structure of methanocaldococcus jannaschii nucleoside kinase - an archaeal member of the ribokinase family (see paper)
    22% identity, 92% coverage of query (63.2 bits)

7c1yA / Q94AT3 Pseudouridine and adp bound structure of pseudouridine kinase (puki) from arabidopsis thaliana (see paper)
    25% identity, 90% coverage of query (63.2 bits)

NK_METJA / Q57849 Nucleoside kinase; NK; ATP-dependent nucleoside monophosphokinase; Cytidine kinase; Guanosine-inosine kinase; EC 2.7.1.213; EC 2.7.1.73 from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii) (see 2 papers)
    22% identity, 92% coverage of query (63.2 bits)

Q4KD57 2-ketogluconokinase (EC 2.7.1.13) from Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5) (see paper)
    25% identity, 80% coverage of query (62.8 bits)

Q9C524 fructokinase (EC 2.7.1.4) from Arabidopsis thaliana (see 2 papers)
    25% identity, 83% coverage of query (62.4 bits)

iolC / P42414 5-dehydro-2-deoxy-D-gluconate kinase (EC 2.7.1.92) from Bacillus subtilis (strain 168) (see 2 papers)
IOLC_BACSU / P42414 5-dehydro-2-deoxygluconokinase; 2-deoxy-5-keto-D-gluconate kinase; DKG kinase; EC 2.7.1.92 from Bacillus subtilis (strain 168) (see paper)
    23% identity, 84% coverage of query (62.0 bits)

7c1zB Atp bound structure of pseudouridine kinase (puki) from arabidopsis thaliana
    26% identity, 90% coverage of query (61.2 bits)

3kzhA / Q8XKB8 Crystal structure of a putative sugar kinase from clostridium perfringens
    24% identity, 84% coverage of query (60.5 bits)

PGA1_c07240 5-dehydro-2-deoxygluconokinase (EC 2.7.1.92) from Phaeobacter inhibens BS107
    26% identity, 81% coverage of query (59.7 bits)

Dshi_2797 Fructokinase (EC 2.7.1.4) from Dinoroseobacter shibae DFL-12
    28% identity, 83% coverage of query (58.5 bits)

PFKB_THETC / D9TT10 ATP-dependent 6-phosphofructokinase; ATP-PFK; Phosphofructokinase; EC 2.7.1.11 from Thermoanaerobacterium thermosaccharolyticum (strain ATCC 7956 / DSM 571 / NCIMB 9385 / NCA 3814 / NCTC 13789 / WDCM 00135 / 2032) (Clostridium thermosaccharolyticum) (see paper)
    20% identity, 85% coverage of query (57.0 bits)

ADK_PHYPA / O49923 Adenosine kinase; AK; Adenosine 5'-phosphotransferase; EC 2.7.1.20 from Physcomitrium patens (Spreading-leaved earth moss) (Physcomitrella patens) (see paper)
    26% identity, 72% coverage of query (56.2 bits)

4k8pA / Q2KDX6 Crystal structure of probable sugar kinase protein from rhizobium etli cfn 42 complexed with 2-ethylbenzyl alcohol
    26% identity, 80% coverage of query (55.1 bits)

4lc4A Crystal structure of probable sugar kinase protein from rhizobium etli cfn 42 complexed with guanosine
    26% identity, 80% coverage of query (55.1 bits)

4kbeA Crystal structure of probable sugar kinase protein from rhizobium etli cfn 42 complexed with benzoguanamine
    26% identity, 80% coverage of query (55.1 bits)

4kanA Crystal structure of probable sugar kinase protein from rhizobium etli cfn 42 complexed with 2-(2,5-dimethyl-1,3-thiazol-4-yl)acetic acid
    26% identity, 80% coverage of query (55.1 bits)

4kalA Crystal structure of probable sugar kinase protein from rhizobium etli cfn 42 complexed with quinoline-3-carboxylic acid
    26% identity, 80% coverage of query (55.1 bits)

4kahA Crystal structure of probable sugar kinase protein from rhizobium etli cfn 42 complexed with 4-bromo-1h-pyrazole
    26% identity, 80% coverage of query (55.1 bits)

4kadA Crystal structure of probable sugar kinase protein from rhizobium etli cfn 42 complexed with n1-(2.3-dihydro-1h-inden-5-yl)acetam
    26% identity, 80% coverage of query (55.1 bits)

4k9iA Crystal structure of probable sugar kinase protein from rhizobium etli cfn 42 complexed with norharmane
    26% identity, 80% coverage of query (55.1 bits)

4k9cA Crystal structure of probable sugar kinase protein from rhizobium etli cfn 42 complexed with n-(hydroxymethyl)benzamide and 4-methyl-3,4- dihydro-2h-1,4-benzoxazine-7-carboxylic acid
    26% identity, 80% coverage of query (55.1 bits)

4k93A Crystal structure of probable sugar kinase protein from rhizobium etli cfn 42 complexed with n-(hydroxymethyl)benzamide
    26% identity, 80% coverage of query (55.1 bits)

4k8tA Crystal structure of probable sugar kinase protein from rhizobium etli cfn 42 complexed with ethyl 3,4-diaminobenzoate
    26% identity, 80% coverage of query (55.1 bits)

4k8cA Crystal structure of probable sugar kinase protein from rhizobium etli cfn 42 complexed with adp
    26% identity, 80% coverage of query (55.1 bits)

4jkuA Crystal structure of probable sugar kinase protein from rhizobium etli cfn 42 complexed with quinaldic acid, nysgrc target 14306
    26% identity, 80% coverage of query (55.1 bits)

4lbxA Crystal structure of probable sugar kinase protein from rhizobium etli cfn 42 complexed with cytidine
    26% identity, 80% coverage of query (55.1 bits)

4k8kA Crystal structure of probable sugar kinase protein from rhizobium etli cfn 42 complexed with 1-(4-methoxyphenyl)-1-cyclopropane and 2- aminoperimidine
    26% identity, 80% coverage of query (55.1 bits)

G4SW45 diphosphate-fructose-6-phosphate 1-phosphotransferase (EC 2.7.1.90) from Methylotuvimicrobium alcaliphilum (see paper)
    27% identity, 86% coverage of query (54.7 bits)

ADK1 / Q9SF85 adenosine kinase 1 (EC 2.7.1.20) from Arabidopsis thaliana (see paper)
ADK1_ARATH / Q9SF85 Adenosine kinase 1; AK 1; Adenosine 5'-phosphotransferase 1; EC 2.7.1.20 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
Q9SF85 adenosine kinase (EC 2.7.1.20) from Arabidopsis thaliana (see paper)
    25% identity, 72% coverage of query (54.3 bits)

3uboA / Q92T17 The crystal structure of adenosine kinase from sinorhizobium meliloti
    26% identity, 78% coverage of query (53.5 bits)

STM4066 / Q8ZKR2 aminoimidazole riboside kinase (EC 2.7.1.223) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 2 papers)
AIRSK_SALTY / Q8ZKR2 Aminoimidazole riboside kinase; AIRs kinase; EC 2.7.1.223 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 2 papers)
Q8ZKR2 aminoimidazole riboside kinase (EC 2.7.1.223) from Salmonella enterica subsp. enterica serovar Typhimurium (see 2 papers)
    26% identity, 84% coverage of query (53.1 bits)

2varA / Q97U29 Crystal structure of sulfolobus solfataricus 2-keto-3-deoxygluconate kinase complexed with 2-keto-3-deoxygluconate (see paper)
    24% identity, 83% coverage of query (52.0 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory