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Searching for up to 100 curated homologs for BPHYT_RS28740 FitnessBrowser__BFirm:BPHYT_RS28740 (296 a.a.)

Found high-coverage hits (≥70%) to 25 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

HSERO_RS06355 2,4-diketo-3-deoxy-L-fuconate hydrolase (EC 3.7.1.26) from Herbaspirillum seropedicae SmR1
    61% identity, 94% coverage of query (358 bits)

C785_RS20550 / A0A2E7P912 5-hydroxy-2,4-dioxopentanoate hydrolase (EC 3.7.1.26) from Herbaspirillum sp. (see paper)
    61% identity, 94% coverage of query (358 bits)

BMULJ_04921 / A0A0H3KT28 2,4-didehydro-3-deoxy-L-fuconate hydrolase (EC 3.7.1.26) from Burkholderia multivorans (strain ATCC 17616 / 249) (see 2 papers)
    61% identity, 94% coverage of query (349 bits)

BPHYT_RS34210 2,4-diketo-3-deoxy-L-rhamnonate hydrolase (EC 3.7.1.-) from Burkholderia phytofirmans PsJN
    60% identity, 93% coverage of query (346 bits)

SM_b21112 L-2,4-diketo-3-deoxyrhamnonate hydrolase; 2,4-dioxopentanoate hydrolase from Sinorhizobium meliloti 1021
    58% identity, 94% coverage of query (338 bits)

UGL_BURL3 / Q39BA7 Ureidoglycolate lyase; UGL; Ureidoglycolase; Ureidoglycolatase; Ureidoglycolate hydrolase; EC 4.3.2.3 from Burkholderia lata (strain ATCC 17760 / DSM 23089 / LMG 22485 / NCIMB 9086 / R18194 / 383) (see paper)
    60% identity, 93% coverage of query (332 bits)

lra6 / Q1NEI7 2,4-didehydro-3-deoxy-L-fuconate hydrolase (EC 3.7.1.26) from Sphingomonas sp. (strain SKA58) (see paper)
    54% identity, 95% coverage of query (295 bits)

8gsrA / Q1NEI7 Crystal structure of l-2,4-diketo-3-deoxyrhamnonate hydrolase from sphingomonas sp. (Apo-form) (see paper)
    54% identity, 94% coverage of query (291 bits)

8gstC Crystal structure of l-2,4-diketo-3-deoxyrhamnonate hydrolase from sphingomonas sp. (Pyruvate bound-form)
    54% identity, 94% coverage of query (291 bits)

6v77B / A0QTY3 Crystal structure of a putative hpce protein from mycobacterium smegmatis
    45% identity, 70% coverage of query (168 bits)

6iymA / K0A9N9 Fumarylacetoacetate hydrolase (eafah) from psychrophilic exiguobacterium antarcticum (see paper)
    43% identity, 78% coverage of query (168 bits)

K0A9N9 fumarylacetoacetase (EC 3.7.1.2) from Exiguobacterium antarcticum (see paper)
    42% identity, 78% coverage of query (165 bits)

3r6oA / B1MJ53 Crystal structure of a probable 2-hydroxyhepta-2,4-diene-1, 7- dioateisomerase from mycobacterium abscessus (see paper)
    37% identity, 83% coverage of query (156 bits)

Y2993_MYCTU / I6Y276 Protein Rv2993c from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
    41% identity, 70% coverage of query (154 bits)

dntG / Q8VUC7 2,4-dihydroxy-5-methyl-6-oxohexa-2,4-dienoate isomerase from Burkholderia cepacia (see 2 papers)
    35% identity, 95% coverage of query (152 bits)

A0A1R4GQY2 3-fumarylpyruvate hydrolase (EC 3.7.1.20) from Corynebacterium glutamicum (see paper)
    38% identity, 73% coverage of query (147 bits)

6j5xA / Q8NLC0 Crystal structure of fumarylpyruvate hydrolase from corynebacterium glutamicum in complex with mn2+ and pyruvate (see paper)
    38% identity, 73% coverage of query (147 bits)

6j5xB Crystal structure of fumarylpyruvate hydrolase from corynebacterium glutamicum in complex with mn2+ and pyruvate
    38% identity, 73% coverage of query (147 bits)

3qdfA / B2HIH3 Crystal structure of 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase from mycobacterium marinum (see paper)
    39% identity, 70% coverage of query (144 bits)

CPH_NEONM / A0A3G9JYJ6 Caffeoylpyruvate hydrolase; CPH; Fungal bioluminescence cycle protein cph; EC 3.7.-.- from Neonothopanus nambi (Agaricus nambi) (see 2 papers)
    35% identity, 70% coverage of query (124 bits)

A0A080VH08 3-fumarylpyruvate hydrolase (EC 3.7.1.20) from Pseudomonas aeruginosa (see paper)
    34% identity, 71% coverage of query (104 bits)

6j5yA / Q9I111 Crystal structure of fumarylpyruvate hydrolase from pseudomonas aeruginosa in complex with mn2+ and pyruvate (see paper)
    34% identity, 71% coverage of query (104 bits)

A0A0M3SVN7 fumarylacetoacetase (EC 3.7.1.2) from Cupriavidus gilardii (see paper)
    34% identity, 71% coverage of query (102 bits)

G2IPX5 maleylpyruvate hydrolase (EC 3.7.1.23) from Sphingobium sp. SYK-6 (see paper)
    35% identity, 77% coverage of query (102 bits)

6jvwB / G2IPX5 Crystal structure of maleylpyruvate hydrolase from sphingobium sp. Syk-6 in complex with manganese (ii) ion and pyruvate (see paper)
    33% identity, 77% coverage of query (100 bits)

Build an alignment

Build an alignment for BPHYT_RS28740 and 25 homologs with ≥ 30% identity

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory