Searching for up to 100 curated homologs for BPHYT_RS31145 FitnessBrowser__BFirm:BPHYT_RS31145 (424 a.a.)
Found high-coverage hits (≥70%) to 68 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
4it1D / Q3KB33 Crystal structure of enolase pfl01_3283 (target efi-502286) from pseudomonas fluorescens pf0-1 with bound magnesium, potassium and tartrate
61% identity, 100% coverage of query (536 bits)
3vc6A / D6Y7Y6 Crystal structure of enolase tbis_1083(target efi-502310) from thermobispora bispora dsm 43833 complexed with magnesium and formate
53% identity, 98% coverage of query (431 bits)
3va8A Crystal structure of enolase fg03645.1 (target efi-502278) from gibberella zeae ph-1 complexed with magnesium, formate and sulfate
50% identity, 100% coverage of query (431 bits)
3nfuA / Q1QUN0 Crystal structure of probable glucarate dehydratase from chromohalobacter salexigens dsm 3043 complexed with magnesium
37% identity, 98% coverage of query (265 bits)
1ec9D / P0AES2 E. Coli glucarate dehydratase bound to xylarohydroxamate (see paper)
34% identity, 98% coverage of query (222 bits)
1ecqA E. Coli glucarate dehydratase bound to 4-deoxyglucarate
34% identity, 98% coverage of query (222 bits)
YgcX / b2787 D-glucarate dehydratase (EC 4.2.1.40) from Escherichia coli K-12 substr. MG1655 (see 6 papers)
gudD / P0AES2 D-glucarate dehydratase (EC 4.2.1.40) from Escherichia coli (strain K12) (see 5 papers)
GUDD_ECOLI / P0AES2 Glucarate dehydratase; GDH; GlucD; D-glucarate dehydratase; EC 4.2.1.40 from Escherichia coli (strain K12) (see 3 papers)
gudD / RF|NP_417267 glucarate dehydratase; EC 4.2.1.40 from Escherichia coli K12 (see 8 papers)
34% identity, 98% coverage of query (221 bits)
gudD / P42206 D-glucarate dehydratase subunit (EC 4.2.1.40) from Pseudomonas putida (see paper)
GUDD_PSEPU / P42206 Glucarate dehydratase; GDH; GlucD; EC 4.2.1.40 from Pseudomonas putida (Arthrobacter siderocapsulatus) (see paper)
35% identity, 99% coverage of query (221 bits)
1ec8A E. Coli glucarate dehydratase bound to product 2,3-dihydroxy-5-oxo- hexanedioate
34% identity, 98% coverage of query (221 bits)
gudD / Q6FFQ2 D-glucarate dehydratase subunit (EC 4.2.1.40) from Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1) (see paper)
GUDD_ACIAD / Q6FFQ2 Glucarate dehydratase; GDH; GlucD; EC 4.2.1.40 from Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1) (see paper)
Q6FFQ2 glucarate dehydratase (EC 4.2.1.40) from Acinetobacter baylyi (see paper)
32% identity, 98% coverage of query (220 bits)
3p0wB / B2UIZ1 Crystal structure of d-glucarate dehydratase from ralstonia solanacearum complexed with mg and d-glucarate
35% identity, 97% coverage of query (218 bits)
1jctA Glucarate dehydratase, n341l mutant orthorhombic form
34% identity, 98% coverage of query (218 bits)
GudX / b2788 glucarate dehydratase-related protein from Escherichia coli K-12 substr. MG1655 (see 2 papers)
GUDX_ECOLI / Q46915 Glucarate dehydratase-related protein; GDH-RP; GlucDRP; EC 4.2.1.- from Escherichia coli (strain K12) (see paper)
gudX / RF|NP_417268 glucarate dehydratase-related protein from Escherichia coli K12
34% identity, 99% coverage of query (216 bits)
3nxlC / Q39KL8 Crystal structure of glucarate dehydratase from burkholderia cepacia complexed with magnesium
36% identity, 99% coverage of query (211 bits)
3n6hB / A6VQF6 Crystal structure of mandelate racemase/muconate lactonizing protein from actinobacillus succinogenes 130z complexed with magnesium/sulfate
33% identity, 98% coverage of query (204 bits)
3pfrA Crystal structure of d-glucarate dehydratase related protein from actinobacillus succinogenes complexed with d-glucarate
32% identity, 98% coverage of query (202 bits)
Build an alignment for BPHYT_RS31145 and 16 homologs with ≥ 30% identity
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D4GYD4 gluconate dehydratase (EC 4.2.1.39) from Haloferax volcanii (see paper)
28% identity, 92% coverage of query (104 bits)
3rcyF Crystal structure of mandelate racemase/muconate lactonizing enzyme- like protein from roseovarius sp. Tm1035
28% identity, 82% coverage of query (88.6 bits)
xacD / D4GP40 D-xylonate dehydratase subunit (EC 4.2.1.25; EC 4.2.1.82) from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (see 3 papers)
XAD_HALVD / D4GP40 D-xylonate dehydratase; XAD; EC 4.2.1.82 from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii) (see 2 papers)
D4GP40 xylonate dehydratase (EC 4.2.1.82) from Haloferax volcanii (see paper)
26% identity, 91% coverage of query (85.9 bits)
catB / A0F0B3 muconate cycloisomerase (EC 5.5.1.1) from Pseudomonas reinekei (see paper)
26% identity, 83% coverage of query (85.1 bits)
3sjnA / A8H9D1 Crystal structure of enolase spea_3858 (target efi-500646) from shewanella pealeana with magnesium bound
27% identity, 84% coverage of query (83.2 bits)
PS417_23670 Muconate cycloisomerase (EC 5.5.1.1) from Pseudomonas simiae WCS417
26% identity, 83% coverage of query (80.1 bits)
catBI / BAA75205.1 muconate cycloisomerase from Frateuria sp. ANA-18 (see paper)
catB1 / BAC82532.1 muconate cycloisomerase from Frateuria sp. ANA-18 (see 3 papers)
25% identity, 83% coverage of query (77.8 bits)
3my9A / A8HTB8 Crystal structure of a muconate cycloisomerase from azorhizobium caulinodans
28% identity, 84% coverage of query (76.3 bits)
araD / Q97U96 D-arabinonate dehydratase subunit (EC 4.2.1.5) from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (see paper)
ARAD_SACS2 / Q97U96 Arabinonate dehydratase; EC 4.2.1.5 from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus) (see paper)
Q97U96 Arabinonate dehydratase (EC 4.2.1.5) from Saccharolobus solfataricus (see paper)
25% identity, 81% coverage of query (73.9 bits)
SSO26655 / Q97VG1 D-xylonate dehydratase subunit (EC 4.2.1.25; EC 4.2.1.82) from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (see paper)
25% identity, 91% coverage of query (73.2 bits)
3fcpA / A6T9N5 Crystal structure of muconate lactonizing enzyme from klebsiella pneumoniae
25% identity, 83% coverage of query (72.0 bits)
2o56A / Q8ZKY6 Crystal structure of a member of the enolase superfamily from salmonella typhimurium
24% identity, 82% coverage of query (69.3 bits)
lyxD / Q9I1Q2 L-lyxonate dehydratase (EC 4.2.1.176) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
Q9I1Q2 L-lyxonate dehydratase (EC 4.2.1.176) from Pseudomonas aeruginosa (see paper)
25% identity, 84% coverage of query (68.2 bits)
3bjsB / Q120Q7 Crystal structure of a member of enolase superfamily from polaromonas sp. Js666
27% identity, 82% coverage of query (67.8 bits)
GAD_SACS2 / Q97U27 D-gluconate/D-galactonate dehydratase; GAD; GNAD; EC 4.2.1.140; EC 4.2.1.39; EC 4.2.1.6 from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus) (see 2 papers)
Q97U27 gluconate/galactonate dehydratase (EC 4.2.1.140) from Saccharolobus solfataricus (see paper)
22% identity, 86% coverage of query (67.4 bits)
GAD_PICTO / Q6L1T2 D-gluconate/D-galactonate dehydratase; GAD; GNAD; EC 4.2.1.140; EC 4.2.1.39; EC 4.2.1.6 from Picrophilus torridus (strain ATCC 700027 / DSM 9790 / JCM 10055 / NBRC 100828 / KAW 2/3) (see paper)
Q6L1T2 gluconate/galactonate dehydratase (EC 4.2.1.140); gluconate dehydratase (EC 4.2.1.39) from Picrophilus torridus (see paper)
21% identity, 91% coverage of query (67.4 bits)
gci / A9CEQ8 D-galactarolactone cycloisomerase monomer (EC 5.5.1.27) from Agrobacterium fabrum (strain C58 / ATCC 33970) (see paper)
GCI_AGRFC / A9CEQ8 D-galactarolactone cycloisomerase; EC 5.5.1.27 from Agrobacterium fabrum (strain C58 / ATCC 33970) (Agrobacterium tumefaciens (strain C58)) (see 2 papers)
A9CEQ8 D-galactarolactone cycloisomerase (EC 5.5.1.27) from Agrobacterium tumefaciens (see paper)
4hpnA / A9CEQ8 Crystal structure of a proposed galactarolactone cycloisomerase from agrobacterium tumefaciens, target efi-500704, with bound ca, ordered loops (see paper)
24% identity, 84% coverage of query (67.4 bits)
3sn0A / Q13PB7 Crystal structure of putative l-alanine-dl-glutamate epimerase from burkholderia xenovorans strain lb400 bound to magnesium and fumarate
24% identity, 83% coverage of query (67.0 bits)
3sn4A Crystal structure of putative l-alanine-dl-glutamate epimerase from burkholderia xenovorans strain lb400 bound to magnesium and alpha- ketoglutarate
24% identity, 83% coverage of query (66.6 bits)
2qq6B / Q1AYK7 Crystal structure of mandelate racemase/muconate lactonizing enzyme- like protein from rubrobacter xylanophilus dsm 9941
25% identity, 80% coverage of query (65.1 bits)
5olcC / G0L7B8 Crystal structure of the 3,6-anhydro-d-galactonate cycloisomerase from zobellia galactanivorans (see paper)
22% identity, 83% coverage of query (65.1 bits)
G4RJQ1 gluconate dehydratase (EC 4.2.1.39) from Thermoproteus tenax (see paper)
24% identity, 86% coverage of query (64.3 bits)
GAD_THETE / Q704D2 D-gluconate dehydratase; EC 4.2.1.39 from Thermoproteus tenax (see 2 papers)
gad / CAF18462.1 gluconate dehydratase from Thermoproteus tenax (see paper)
24% identity, 86% coverage of query (64.3 bits)
2ps2A / Q2U1E8 Crystal structure of putative mandelate racemase/muconate lactonizing enzyme from aspergillus oryzae
23% identity, 77% coverage of query (62.4 bits)
NSAR_BACCR / Q81IL5 N-succinyl-L-Arg/Lys racemase; N-succinyl amino acid racemase; NSAR; EC 5.1.1.- from Bacillus cereus (strain ATCC 14579 / DSM 31 / CCUG 7414 / JCM 2152 / NBRC 15305 / NCIMB 9373 / NCTC 2599 / NRRL B-3711) (see paper)
2p88A / Q81IL5 Crystal structure of n-succinyl arg/lys racemase from bacillus cereus atcc 14579 (see paper)
22% identity, 84% coverage of query (61.2 bits)
2p8cA Crystal structure of n-succinyl arg/lys racemase from bacillus cereus atcc 14579 complexed with n-succinyl arg.
22% identity, 84% coverage of query (61.2 bits)
2p8bA Crystal structure of n-succinyl arg/lys racemase from bacillus cereus atcc 14579 complexed with n-succinyl lys.
22% identity, 84% coverage of query (61.2 bits)
C3HPD_STAND / D7A0Y2 Cis-3-hydroxy-L-proline dehydratase; c3LHyp dehydratase; c3LHypD; EC 4.2.1.171 from Starkeya novella (strain ATCC 8093 / DSM 506 / JCM 20403 / CCM 1077 / IAM 12100 / NBRC 12443 / NCIMB 10456) (see paper)
23% identity, 78% coverage of query (60.1 bits)
tfdD / AAT99367.1 TfdD from Sphingomonas sp. TFD44 (see paper)
25% identity, 76% coverage of query (60.1 bits)
2ox4C / Q5NN22 Crystal structure of putative dehydratase from zymomonas mobilis zm4
23% identity, 82% coverage of query (58.2 bits)
C3HPD_ROSAI / A0NXQ8 Cis-3-hydroxy-L-proline dehydratase; c3LHyp dehydratase; c3LHypD; EC 4.2.1.171 from Roseibium aggregatum (strain ATCC 25650 / DSM 13394 / JCM 20685 / NBRC 16684 / NCIMB 2208 / IAM 12614 / B1) (Stappia aggregata) (see paper)
A0NXQ8 cis-L-3-hydroxyproline dehydratase (EC 4.2.1.171) from Roseibium aggregatum (see paper)
22% identity, 85% coverage of query (57.4 bits)
4mggA / A0NXQ8 Crystal structure of an enolase (mandelate racemase subgroup) from labrenzia aggregata iam 12614 (target nysgrc-012903) with bound mg, space group p212121
23% identity, 85% coverage of query (57.4 bits)
3hpfA Crystal structure of the mutant y90f of divergent galactarate dehydratase from oceanobacillus iheyensis complexed with mg and galactarate
22% identity, 87% coverage of query (57.0 bits)
IMND2_ENTGE / C9A1P5 D-galactonate dehydratase family member EGBG_02030 from Enterococcus gallinarum (strain EG2) (see paper)
23% identity, 75% coverage of query (56.6 bits)
AXEP_MARSH / A4AQI7 L-Ala-D/L-amino acid epimerase; EC 5.1.1.- from Maribacter sp. (strain HTCC2170 / KCCM 42371) (see paper)
24% identity, 71% coverage of query (56.6 bits)
3es7A / Q8EMJ9 Crystal structure of divergent enolase from oceanobacillus iheyensis complexed with mg and l-malate. (see paper)
22% identity, 87% coverage of query (56.2 bits)
3cb3A / Q12GE3 Crystal structure of l-talarate dehydratase from polaromonas sp. Js666 complexed with mg and l-glucarate
25% identity, 89% coverage of query (55.8 bits)
Ob2843 / Q8EMJ9 galactarate dehydratase (D-threo-forming) (EC 4.2.1.158) from Oceanobacillus iheyensis (strain DSM 14371 / CIP 107618 / JCM 11309 / KCTC 3954 / HTE831) (see paper)
GALRD_OCEIH / Q8EMJ9 Galactarate dehydratase (D-threo-forming); GalrD; GalrD-II; EC 4.2.1.158 from Oceanobacillus iheyensis (strain DSM 14371 / CIP 107618 / JCM 11309 / KCTC 3954 / HTE831) (see paper)
Q8EMJ9 galactarate dehydratase (D-threo-forming) (EC 4.2.1.158) from Oceanobacillus iheyensis (see paper)
22% identity, 87% coverage of query (55.8 bits)
2og9A Crystal structure of mandelate racemase/muconate lactonizing enzyme from polaromonas sp. Js666
24% identity, 82% coverage of query (55.8 bits)
3dg6A / A0QTN8 Crystal structure of muconate lactonizing enzyme from mucobacterium smegmatis complexed with muconolactone (see paper)
23% identity, 87% coverage of query (54.7 bits)
3ozmD Crystal structure of enolase superfamily member from bordetella bronchiseptica complexed with mg, m-xylarate and l-lyxarate
26% identity, 83% coverage of query (54.7 bits)
3ozmA / A0A0H3LT39 Crystal structure of enolase superfamily member from bordetella bronchiseptica complexed with mg, m-xylarate and l-lyxarate
26% identity, 83% coverage of query (54.3 bits)
3op2A Crystal structure of putative mandelate racemase from bordetella bronchiseptica rb50 complexed with 2-oxoglutarate/phosphate
25% identity, 83% coverage of query (53.9 bits)
MAND_ECOL6 / Q8FHC7 D-galactonate dehydratase family member RspA; D-mannonate dehydratase; Starvation sensing protein RspA homolog; EC 4.2.1.-; EC 4.2.1.8 from Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) (see paper)
22% identity, 83% coverage of query (53.5 bits)
4il2B / Q8FHC7 Crystal structure of d-mannonate dehydratase (rspa) from e. Coli cft073 (efi target efi-501585)
22% identity, 83% coverage of query (53.1 bits)
MAND2_CAUSK / B0T4L2 D-mannonate dehydratase Caul1835; ManD; EC 4.2.1.8 from Caulobacter sp. (strain K31) (see paper)
22% identity, 87% coverage of query (52.8 bits)
4m0xA / Q8G9L1 Crystal structure of 2-chloromuconate cycloisomerase from rhodococcus opacus 1cp (see paper)
24% identity, 83% coverage of query (52.0 bits)
4dn1A / A9CL63 Crystal structure of an enolase (mandelate racemase subgroup member) from agrobacterium tumefaciens (target efi-502088) with bound mg and formate
23% identity, 89% coverage of query (51.6 bits)
3fv9C / A3SNG0 Crystal structure of putative mandelate racemase/muconatelactonizing enzyme from roseovarius nubinhibens ism complexed with magnesium
26% identity, 83% coverage of query (51.2 bits)
3n4eA / A1AYL4 Crystal structure of mandelate racemase/muconate lactonizing protein from paracoccus denitrificans pd1222
22% identity, 86% coverage of query (50.8 bits)
IMAND_PSECP / B8HCK2 D-galactonate dehydratase family member Achl_0790 from Pseudarthrobacter chlorophenolicus (strain ATCC 700700 / DSM 12829 / CIP 107037 / JCM 12360 / KCTC 9906 / NCIMB 13794 / A6) (Arthrobacter chlorophenolicus) (see paper)
22% identity, 84% coverage of query (50.8 bits)
4h1zB / Q92ZS5 Crystal structure of putative isomerase from sinorhizobium meliloti, open loop conformation (target efi-502104)
22% identity, 83% coverage of query (46.2 bits)
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Lawrence Berkeley National Laboratory