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Searching for up to 100 curated homologs for BPHYT_RS32970 FitnessBrowser__BFirm:BPHYT_RS32970 (210 a.a.)

Found high-coverage hits (≥70%) to 30 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

4jbbA / A6TBY7 Crystal structure of glutathione s-transferase a6tby7(target efi- 507184) from klebsiella pneumoniae mgh 78578, gsh complex
    56% identity, 95% coverage of query (219 bits)

YfcF / b2301 glutathione S-transferase YfcF (EC 2.5.1.18) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
yfcF / P77544 glutathione S-transferase YfcF (EC 2.5.1.18) from Escherichia coli (strain K12) (see 2 papers)
YFCF_ECOLI / P77544 Glutathione S-transferase YfcF; EC 2.5.1.18 from Escherichia coli (strain K12) (see paper)
    51% identity, 98% coverage of query (209 bits)

3bbyA / P77544 Crystal structure of glutathione s-transferase (np_416804.1) from escherichia coli k12 at 1.85 a resolution
    50% identity, 96% coverage of query (195 bits)

4isdA / C5A7Z5 Crystal structure of glutathione transferase homolog from burkholderia gl bgr1, target efi-501803, with bound glutathione
    50% identity, 96% coverage of query (180 bits)

GSTT3_MOUSE / Q99L20 Glutathione S-transferase theta-3; EC 2.5.1.18 from Mus musculus (Mouse) (see paper)
    31% identity, 71% coverage of query (54.7 bits)

Build an alignment

Build an alignment for BPHYT_RS32970 and 5 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

MAAI_RAT / P57113 Maleylacetoacetate isomerase; MAAI; GSTZ1-1; Glutathione S-transferase zeta 1; EC 5.2.1.2; EC 2.5.1.18 from Rattus norvegicus (Rat) (see paper)
    26% identity, 72% coverage of query (53.9 bits)

A0A023JCC0 glutathione transferase (EC 2.5.1.18) from Macaca fascicularis (see paper)
    31% identity, 71% coverage of query (53.1 bits)

A0A023JCR6 glutathione transferase (EC 2.5.1.18) from Macaca mulatta (see paper)
    30% identity, 71% coverage of query (50.8 bits)

GSTZ1_ARATH / Q9ZVQ3 Glutathione S-transferase Z1; AtGSTZ1; GST class-zeta member 1; Glutathione S-transferase 18; Maleylacetone isomerase; MAI; EC 2.5.1.18; EC 5.2.1.- from Arabidopsis thaliana (Mouse-ear cress) (see paper)
    27% identity, 91% coverage of query (50.4 bits)

2cz2A / Q9WVL0 Crystal structure of glutathione transferase zeta 1-1 (maleylacetoacetate isomerase) from mus musculus (form-1 crystal)
    25% identity, 72% coverage of query (48.9 bits)

Q9WVL0 Maleylacetoacetate isomerase; MAAI; GSTZ1-1; Glutathione S-transferase zeta 1; EC 5.2.1.2; EC 2.5.1.18 from Mus musculus (Mouse)
    25% identity, 72% coverage of query (48.9 bits)

4hojA / O33374 Crystal structure of glutathione transferase homolog from neisseria gonorrhoeae, target efi-501841, with bound glutathione
    27% identity, 85% coverage of query (48.5 bits)

6f70A / A0A384E158 Crystal structure of glutathione transferase omega 6s from trametes versicolor (see paper)
    28% identity, 78% coverage of query (47.4 bits)

6f71A Crystal structure of glutathione transferase omega 6s from trametes versicolor in complex with naringenin
    28% identity, 78% coverage of query (47.4 bits)

4kdxA / B1FZ96 Crystal structure of a glutathione transferase family member from burkholderia graminis, target efi-507264, bound gsh, ordered domains, space group p21, form(1)
    28% identity, 78% coverage of query (46.6 bits)

1fw1A / O43708 Glutathione transferase zeta/maleylacetoacetate isomerase (see paper)
    25% identity, 75% coverage of query (46.6 bits)

HPM2_HYPSB / B3FWR8 Glutathione S-transferase hmp2; Hypothemycin biosynthesis cluster protein hpm2; EC 2.5.1.18 from Hypomyces subiculosus (Nectria subiculosa) (see 10 papers)
    27% identity, 70% coverage of query (44.7 bits)

GSTZ1 / O43708 maleylacetoacetate isomerase/glutathione transferase ζ monomer (EC 2.5.1.18; EC 5.2.1.2) from Homo sapiens (see 11 papers)
MAAI_HUMAN / O43708 Maleylacetoacetate isomerase; MAAI; GSTZ1-1; Glutathione S-transferase zeta 1; EC 5.2.1.2; EC 2.5.1.18 from Homo sapiens (Human) (see 3 papers)
O43708 glutathione transferase (EC 2.5.1.18); maleylacetoacetate isomerase (EC 5.2.1.2) from Homo sapiens (see 8 papers)
    24% identity, 75% coverage of query (43.1 bits)

8ax0A Crystal structure of trametes versicolor glutathione transferase omega 3s in complex with sodium nitroprusside
    26% identity, 76% coverage of query (42.4 bits)

8awzA / A0A384E145 Crystal structure of trametes versicolor glutathione transferase omega 3s in complex with dinitrosyl glutathionyl iron complex (dngic) (see paper)
    26% identity, 76% coverage of query (42.4 bits)

6hpeA Crystal structure of glutathione transferase omega 3s from trametes versicolor in complex with the glutathione adduct of phenethyl- isothiocyanate
    26% identity, 76% coverage of query (42.4 bits)

6f6aA Crystal structure of glutathione transferase omega 3s from trametes versicolor in complex with dihydrowogonin from wild-cherry extract
    26% identity, 76% coverage of query (42.4 bits)

6f69A Crystal structure of glutathione transferase omega 3s from trametes versicolor in complex with 2,3,4-trihydroxybenzophenone
    26% identity, 76% coverage of query (42.4 bits)

6f68A Crystal structure glutathione transferase omega 3s from trametes versicolor in complex with 2,4,4'-trihydroxybenzophenone
    26% identity, 76% coverage of query (42.4 bits)

6f67A Crystal structure of glutathione transferase omega 3s from trametes versicolor in complex with 3,4-dihydroxybenzophenone
    26% identity, 76% coverage of query (42.4 bits)

6f66A Crystal structure of glutathione transferase omega 3s from trametes versicolor in complex with 2,4-dihydroxybenzophenone
    26% identity, 76% coverage of query (42.4 bits)

6f4kA Crystal structure of glutathione transferase omega 3s from trametes versicolor in complex with hexyl-glutathione
    26% identity, 76% coverage of query (42.4 bits)

6f4fA Crystal structure of glutathione transferase omega 3s from trametes versicolor in complex with glutathionyl-s-dinitrobenzene
    26% identity, 76% coverage of query (42.4 bits)

8ax1A Crystal structure of trametes versicolor glutathione transferase omega 3s in complex with hydroxy-tetranitro-nitrosyl-ruthenate
    26% identity, 76% coverage of query (42.4 bits)

6f51A Crystal structure of glutathione transferase omega 3s from trametes versicolor in complex with glutathionyl-phenylacetophenone
    26% identity, 76% coverage of query (42.4 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory