Searching for up to 100 curated homologs for BPHYT_RS34225 FitnessBrowser__BFirm:BPHYT_RS34225 (346 a.a.)
Found high-coverage hits (≥70%) to 58 curated proteins.
Removed hits that are identical to the query, leaving 57
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
PLD_MICLT / Q76KC2 Pyridoxal 4-dehydrogenase; EC 1.1.1.107 from Microbacterium luteolum (Aureobacterium luteolum) (see paper)
52% identity, 95% coverage of query (347 bits)
SMc02775 D-arabinose 1-dehydrogenase from Sinorhizobium meliloti 1021
52% identity, 88% coverage of query (283 bits)
FCDH_PSESP / Q52472 D-threo-aldose 1-dehydrogenase; L-fucose dehydrogenase; EC 1.1.1.122 from Pseudomonas sp.
Q52472 D-threo-aldose 1-dehydrogenase (EC 1.1.1.122) from Pseudomonas sp. (see paper)
41% identity, 90% coverage of query (228 bits)
Build an alignment for BPHYT_RS34225 and 3 homologs with ≥ 30% identity
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Q6BDJ2 L-galactose 1-dehydrogenase (EC 1.1.1.316) from Spinacia oleracea (see paper)
GDH / BAD32687.1 L-galactose dehydrogenase from Spinacia oleracea (see paper)
28% identity, 90% coverage of query (120 bits)
7svqA / Q6BDJ2 Crystal structure of l-galactose dehydrogenase from spinacia oleracea in complex with NAD+ (see paper)
28% identity, 90% coverage of query (120 bits)
Q84L20 L-galactose 1-dehydrogenase (EC 1.1.1.316) from Malus domestica (see paper)
28% identity, 90% coverage of query (120 bits)
LGALDH / O81884 L-galactose dehydrogenase (EC 1.1.1.316) from Arabidopsis thaliana (see paper)
GALDH_ARATH / O81884 L-galactose dehydrogenase; At-GalDH; L-GalDH; EC 1.1.1.316 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
O81884 L-galactose 1-dehydrogenase (EC 1.1.1.316) from Arabidopsis thaliana (see paper)
L-GalDH / CAD10386.1 L-galactose dehydrogenase from Arabidopsis thaliana (see paper)
28% identity, 89% coverage of query (119 bits)
C0LVA5 L-galactose 1-dehydrogenase (EC 1.1.1.316) from Actinidia eriantha (see paper)
27% identity, 88% coverage of query (117 bits)
7eziA / Q2QQV2 Rice l-galactose dehydrogenase (apo form)
30% identity, 90% coverage of query (108 bits)
7ezlA Rice l-galactose dehydrogenase (holo form)
30% identity, 90% coverage of query (108 bits)
E9M5S4 L-galactose 1-dehydrogenase (EC 1.1.1.316) from Citrus unshiu (see paper)
27% identity, 89% coverage of query (107 bits)
lgaA / A6KWY2 L-galactose dehydrogenase from Phocaeicola vulgatus (strain ATCC 8482 / DSM 1447 / JCM 5826 / CCUG 4940 / NBRC 14291 / NCTC 11154) (see paper)
27% identity, 93% coverage of query (106 bits)
1pz0A / P46336 Structure of NADPH-dependent family 11 aldo-keto reductase akr11a(holo) (see paper)
26% identity, 89% coverage of query (100 bits)
IOLS_BACSU / P46336 Aldo-keto reductase IolS; AKR11A; Vegetative protein 147; VEG147; EC 1.1.1.- from Bacillus subtilis (strain 168) (see 4 papers)
26% identity, 89% coverage of query (100 bits)
YdjG / b1771 NADH-dependent methylglyoxal reductase from Escherichia coli K-12 substr. MG1655 (see 5 papers)
ydjG / P77256 NADH-dependent methylglyoxal reductase from Escherichia coli (strain K12) (see 4 papers)
AKRMG_ECOLI / P77256 NADH-specific methylglyoxal reductase; AKR11B2; EC 1.1.1.- from Escherichia coli (strain K12) (see 3 papers)
ydjG / RF|NP_416285 uncharacterized oxidoreductase ydjG from Escherichia coli K12 (see paper)
25% identity, 92% coverage of query (98.2 bits)
1ynpB / Q9KE47 Aldo-keto reductase akr11c1 from bacillus halodurans (apo form) (see paper)
27% identity, 90% coverage of query (82.4 bits)
1ynqB Aldo-keto reductase akr11c1 from bacillus halodurans (holo form)
27% identity, 90% coverage of query (82.4 bits)
PR / Q3L181 perakine reductase (EC 1.1.1.317) from Rauvolfia serpentina (see 2 papers)
PERR_RAUSE / Q3L181 Perakine reductase; EC 1.1.1.317 from Rauvolfia serpentina (Serpentine wood) (Ophioxylon serpentinum) (see 2 papers)
Q3L181 perakine reductase (EC 1.1.1.317) from Rauvolfia serpentina (see 3 papers)
25% identity, 90% coverage of query (72.8 bits)
YajO / b0419 1-deoxyxylulose-5-phosphate synthase YajO from Escherichia coli K-12 substr. MG1655 (see 7 papers)
yajO / P77735 1-deoxyxylulose-5-phosphate synthase YajO from Escherichia coli (strain K12) (see 6 papers)
YAJO_ECOLI / P77735 1-deoxyxylulose-5-phosphate synthase YajO; EC 1.1.-.- from Escherichia coli (strain K12) (see 2 papers)
P77735 1-deoxy-D-xylulose-5-phosphate synthase (EC 2.2.1.7) from Escherichia coli (see paper)
26% identity, 90% coverage of query (72.4 bits)
VRDA_ASPPA / B9WYE6 Versiconal hemiacetal acetate reductase; VHA reductase; EC 1.1.1.353 from Aspergillus parasiticus (see paper)
B9WYE6 versiconal hemiacetal acetate reductase (EC 1.1.1.353) from Aspergillus parasiticus (see paper)
24% identity, 90% coverage of query (70.9 bits)
6ow0B / Q194Q1 Crystal structure of mithramycin 3-side chain keto-reductase mtmw in complex with NAD+ and peg (see paper)
26% identity, 88% coverage of query (69.7 bits)
6ow0A / Q194Q1 Crystal structure of mithramycin 3-side chain keto-reductase mtmw in complex with NAD+ and peg (see paper)
25% identity, 88% coverage of query (69.3 bits)
AFTS1_ALTAL / Q75ZG3 Aldo-keto reductase AFTS1; AF-toxin biosynthesis protein S1; EC 1.1.1.- from Alternaria alternata (Alternaria rot fungus) (Torula alternata) (see 3 papers)
26% identity, 81% coverage of query (68.9 bits)
KCAB_ARATH / O23016 Probable voltage-gated potassium channel subunit beta; K(+) channel subunit beta; Potassium voltage beta 1; KV-beta1; EC 1.1.1.- from Arabidopsis thaliana (Mouse-ear cress) (see paper)
24% identity, 97% coverage of query (67.8 bits)
1ynpA Aldo-keto reductase akr11c1 from bacillus halodurans (apo form)
24% identity, 90% coverage of query (67.4 bits)
mtmW / Q194Q1 mithramycin dehydrogenase from Streptomyces argillaceus (see 2 papers)
25% identity, 88% coverage of query (65.9 bits)
3v0sA / Q3L181 Crystal structure of perakine reductase, founder member of a novel akr subfamily with unique conformational changes during NADPH binding (see paper)
24% identity, 90% coverage of query (64.3 bits)
KCAB_ORYSJ / Q40648 Probable voltage-gated potassium channel subunit beta; K(+) channel subunit beta; EC 1.1.1.- from Oryza sativa subsp. japonica (Rice) (see paper)
24% identity, 91% coverage of query (63.5 bits)
6kikA / Q9X265 Crystal structure of a thermostable aldo-keto reductase tm1743 in complex with inhibitor tolrestat (see paper)
24% identity, 95% coverage of query (62.4 bits)
6kiyA Crystal structure of a thermostable aldo-keto reductase tm1743 in complex with inhibitor epalrestat
24% identity, 95% coverage of query (62.4 bits)
Q9X265 carbonyl reductase (NADPH) (EC 1.1.1.184) from Thermotoga maritima (see 2 papers)
24% identity, 95% coverage of query (62.0 bits)
5danA Crystal structure of a novel aldo keto reductase tm1743 from thermotoga maritima in complex with NADP+
24% identity, 95% coverage of query (62.0 bits)
GME68_PESMI / A0A5B8YXI2 Aryl-alcohol dehydrogenase GME11368; Dibenzodioxocinones biosynthesis cluster protein GME11368; EC 1.1.1.- from Pestalotiopsis microspora (see 2 papers)
24% identity, 89% coverage of query (60.5 bits)
1pz1A / P80874 Structure of NADPH-dependent family 11 aldo-keto reductase akr11b(holo) (see paper)
25% identity, 85% coverage of query (60.5 bits)
KCAB_SCHPO / O59826 Putative voltage-gated potassium channel subunit beta; K(+) channel subunit beta; EC 1.1.1.- from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
23% identity, 89% coverage of query (60.5 bits)
GS69_BACSU / P80874 Aldo-keto reductase YhdN; AKR11B; General stress protein 69; GSP69; EC 1.1.1.- from Bacillus subtilis (strain 168) (see 3 papers)
25% identity, 85% coverage of query (60.1 bits)
YI7E_SCHPO / Q9P7U2 Putative aryl-alcohol dehydrogenase C977.14c; EC 1.1.1.- from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
23% identity, 89% coverage of query (59.7 bits)
8hw0A / A0A6B8QIS5 The structure of akr6d1
24% identity, 89% coverage of query (59.7 bits)
AMT2_ALTAL / Q75ZG2 Aldo-keto reductase AMT2; AM-toxin biosynthesis protein 2; EC 1.1.1.- from Alternaria alternata (Alternaria rot fungus) (Torula alternata) (see 3 papers)
25% identity, 93% coverage of query (59.3 bits)
eryBII / A4F7P4 dTDP-(2R,6S)-6-hydroxy-2-methyl-3-oxo-3,6-dihydro-2H-pyran-4-olate 3-ketoreductase (dTDP-4-dehydro-2,6-dideoxy-α-D-allose-forming) from Saccharopolyspora erythraea (strain ATCC 11635 / DSM 40517 / JCM 4748 / NBRC 13426 / NCIMB 8594 / NRRL 2338) (see 2 papers)
27% identity, 86% coverage of query (58.5 bits)
KCAB2_BOVIN / Q27955 Voltage-gated potassium channel subunit beta-2; K(+) channel subunit beta-2; Kv-beta-2; EC 1.1.1.- from Bos taurus (Bovine) (see paper)
23% identity, 89% coverage of query (58.5 bits)
8hnqA / A0A6B8QJ47 The structure of a alcohol dehydrogenase akr13b2 with NADP
25% identity, 88% coverage of query (58.5 bits)
KCAB2_HUMAN / Q13303 Voltage-gated potassium channel subunit beta-2; K(+) channel subunit beta-2; Kv-beta-2; hKvbeta2; EC 1.1.1.- from Homo sapiens (Human) (see 4 papers)
23% identity, 89% coverage of query (58.2 bits)
7wf3C / Q13303 Composite map of human kv1.3 channel in apo state with beta subunits (see paper)
23% identity, 89% coverage of query (57.8 bits)
KCAB2_MOUSE / P62482 Voltage-gated potassium channel subunit beta-2; K(+) channel subunit beta-2; Kv-beta-2; Neuroimmune protein F5; EC 1.1.1.- from Mus musculus (Mouse) (see 8 papers)
KCAB2_RAT / P62483 Voltage-gated potassium channel subunit beta-2; K(+) channel subunit beta-2; Kv-beta-2; EC 1.1.1.- from Rattus norvegicus (Rat) (see 19 papers)
23% identity, 89% coverage of query (55.5 bits)
1exbA Structure of the cytoplasmic beta subunit-t1 assembly of voltage- dependent k channels
23% identity, 89% coverage of query (55.5 bits)
6hg6A / A0A1S8QGT2 Clostridium beijerinckii aldo-keto reductase cbei_3974 with NADPH (see paper)
26% identity, 77% coverage of query (55.1 bits)
YH5B_SCHPO / O94315 Uncharacterized oxidoreductase C215.11c; EC 1.-.-.- from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
24% identity, 93% coverage of query (55.1 bits)
4exaF / Q9HUH3 Crystal structure of the pa4992, the putative aldo-keto reductase from pseudomona aeruginosa (see paper)
29% identity, 81% coverage of query (55.1 bits)
3eauA Voltage-dependent k+ channel beta subunit in complex with cortisone
23% identity, 89% coverage of query (55.1 bits)
KCAB2_XENLA / Q9PTM5 Voltage-gated potassium channel subunit beta-2; K(+) channel subunit beta-2; Kv-beta-2; EC 1.1.1.- from Xenopus laevis (African clawed frog) (see paper)
22% identity, 89% coverage of query (54.3 bits)
YgdS / b2834 putative NADP(H)-dependent aldo-keto reductase Tas from Escherichia coli K-12 substr. MG1655 (see 6 papers)
1lqaA / P0A9T4 Tas protein from escherichia coli in complex with NADPH (see paper)
tas protein Tas from Escherichia coli str. K12 substr. MG1655 (see paper)
24% identity, 90% coverage of query (51.6 bits)
P0A9T4 Protein tas from Escherichia coli (strain K12)
24% identity, 90% coverage of query (51.6 bits)
7bc1A / A9CEY6 Crystal structure of aldo-keto reductase from agrobacterium tumefaciens in a ternary complex with NADPH and glucose (see paper)
26% identity, 86% coverage of query (50.8 bits)
smoB / A9CEY6 6-dehydroglucose reductase monomer (EC 1.1.1.432) from Agrobacterium fabrum (strain C58 / ATCC 33970) (see paper)
DHGRD_AGRFC / A9CEY6 6-dehydroglucose reductase; SQ monooxygenase cluster protein B; EC 1.1.1.432 from Agrobacterium fabrum (strain C58 / ATCC 33970) (Agrobacterium tumefaciens (strain C58)) (see paper)
25% identity, 86% coverage of query (49.7 bits)
STCV_EMENI / Q00727 Norsolorinic acid reductase stcV; Sterigmatocystin biosynthesis cluster protein V; EC 1.1.1.- from Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) (see 8 papers)
stcV putative sterigmatocystin biosynthesis dehydrogenase stcV; EC 1.1.1.- from Emericella nidulans (see paper)
25% identity, 87% coverage of query (49.3 bits)
YAKC_SCHPO / Q09923 Aldo-keto reductase yakc [NADP(+)]; EC 1.1.1.- from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
yak3 aldose reductase YakC from Schizosaccharomyces pombe (see 3 papers)
21% identity, 93% coverage of query (49.3 bits)
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