Searching for up to 100 curated homologs for BPHYT_RS34470 FitnessBrowser__BFirm:BPHYT_RS34470 (285 a.a.)
Found high-coverage hits (≥70%) to 67 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
Pf1N1B4_771 ABC transporter for L-asparagine and L-glutamate, periplasmic substrate-binding component from Pseudomonas fluorescens FW300-N1B4
59% identity, 99% coverage of query (337 bits)
2ia4B / A0A0H2UXX1 Crystal structure of novel amino acid binding protein from shigella flexneri
59% identity, 96% coverage of query (337 bits)
GASBP_PSEAE / Q9I402 L-glutamate/L-aspartate-binding protein from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
TC 3.A.1.3.22 / Q9I402 Probable binding protein component of ABC transporter, component of Amino acid transporter, AatJMQP. Probably transports L-glutamic acid, D-glutamine acid, L-glutamine and N-acetyl L-glutamic acid (Johnson et al. 2008). Very similar to 3.A.1.3.19 of P. putida from Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
57% identity, 100% coverage of query (337 bits)
2vhaA Debp
58% identity, 95% coverage of query (336 bits)
GltI / b0655 glutamate/aspartate ABC transporter periplasmic binding protein (EC 7.4.2.1) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
GltI / P37902 glutamate/aspartate ABC transporter periplasmic binding protein (EC 7.4.2.1) from Escherichia coli (strain K12) (see 3 papers)
GLTI_ECOLI / P37902 Glutamate/aspartate import solute-binding protein from Escherichia coli (strain K12) (see 3 papers)
TC 3.A.1.3.4 / P37902 YBEJ aka GltI aka B0655, component of Glutamate/aspartate porter from Escherichia coli (see 6 papers)
gltI / GB|BAA35307.2 glutamate-aspartate periplasmic-binding protein from Escherichia coli K12 (see 6 papers)
58% identity, 94% coverage of query (332 bits)
PfGW456L13_4770 ABC transporter for L-Asparagine and possibly other L-amino acids, periplasmic substrate-binding component from Pseudomonas fluorescens GW456-L13
58% identity, 99% coverage of query (327 bits)
AO353_16290 ABC transporter for L-aspartate, L-asparagine, L-glutamate, and L-glutamine, periplasmic substrate-binding component from Pseudomonas fluorescens FW300-N2E3
57% identity, 100% coverage of query (326 bits)
TC 3.A.1.3.19 / Q88NY2 PP1071, component of Acidic amino acid uptake porter, AatJMQP from Pseudomonas putida (strain KT2440) (see paper)
56% identity, 95% coverage of query (314 bits)
8ovoA / P37902,P42212 X-ray structure of the sf-iglusnfr-s72a in complex with l-aspartate
57% identity, 87% coverage of query (294 bits)
4zv1A An ancestral arginine-binding protein bound to arginine (see paper)
32% identity, 77% coverage of query (112 bits)
4zv2A An ancestral arginine-binding protein bound to glutamine
31% identity, 77% coverage of query (110 bits)
GLNH_BACSU / O34563 ABC transporter glutamine-binding protein GlnH from Bacillus subtilis (strain 168) (see paper)
30% identity, 86% coverage of query (109 bits)
5eyfB / Q3XZW5 Crystal structure of solute-binding protein from enterococcus faecium with bound glutamate
31% identity, 76% coverage of query (103 bits)
Build an alignment for BPHYT_RS34470 and 13 homologs with ≥ 30% identity
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6svfA / Q9WZ62 Crystal structure of the p235gk mutant of argbp from t. Maritima (see paper)
29% identity, 77% coverage of query (97.4 bits)
5t0wA Crystal structure of the ancestral amino acid-binding protein anccdt- 1, a precursor of cyclohexadienyl dehydratase
28% identity, 84% coverage of query (89.4 bits)
2q2cA Crystal structures of the arginine-, lysine-, histidine-binding protein artj from the thermophilic bacterium geobacillus stearothermophilus
29% identity, 80% coverage of query (87.4 bits)
2pvuA Crystal structures of the arginine-, lysine-, histidine-binding protein artj from the thermophilic bacterium geobacillus stearothermophilus
29% identity, 80% coverage of query (87.0 bits)
2q2aA / D0VWX8 Crystal structures of the arginine-, lysine-, histidine-binding protein artj from the thermophilic bacterium geobacillus stearothermophilus (see paper)
29% identity, 80% coverage of query (86.7 bits)
2yjpA / Q5F5B5 Crystal structure of the solute receptors for l-cysteine of neisseria gonorrhoeae (see paper)
27% identity, 83% coverage of query (84.0 bits)
TcyJ / b1920 cystine ABC transporter periplasmic binding protein (EC 7.4.2.12) from Escherichia coli K-12 substr. MG1655 (see 12 papers)
tcyJ / P0AEM9 cystine ABC transporter periplasmic binding protein (EC 7.4.2.12) from Escherichia coli (strain K12) (see 13 papers)
TCYJ_ECOLI / P0AEM9 L-cystine-binding protein TcyJ; CBP; Protein FliY; Sulfate starvation-induced protein 7; SSI7 from Escherichia coli (strain K12) (see 6 papers)
TC 3.A.1.3.10 / P0AEM9 Cystine-binding periplasmic protein FLIY aka CysX aka B1920, component of Cystine/cysteine/diaminopimelate transporter, CysXYZ; these proteins are also designated FliY/YecS/YecC from Escherichia coli (see 7 papers)
27% identity, 87% coverage of query (79.3 bits)
4ymxA / Q8RCC4 Crystal structure of the substrate binding protein of an amino acid abc transporter (see paper)
27% identity, 77% coverage of query (77.8 bits)
ARGBP_PSEAE / G3XD47 L-arginine-binding protein from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see 3 papers)
TC 3.A.1.3.11 / O50181 AotJ aka PA0888, component of Arginine/ornithine (but not lysine) porter from Pseudomonas aeruginosa (see 2 papers)
29% identity, 89% coverage of query (76.6 bits)
AAC45332.1 high affinity cystine binding protein from Lactobacillus reuteri (see 4 papers)
24% identity, 87% coverage of query (75.1 bits)
6h2tA / P96257 Glnh bound to glu, mycobacterium tuberculosis (see paper)
25% identity, 88% coverage of query (74.3 bits)
6h20A Glnh bound to asn, mycobacterium tuberculosis
25% identity, 91% coverage of query (73.9 bits)
6h1uA Glnh bound to asp, mycobacterium tuberculosis
25% identity, 91% coverage of query (73.9 bits)
5owfA Structure of a lao-binding protein mutant with glutamine
28% identity, 81% coverage of query (73.6 bits)
1lafE / P02911 Structural bases for multiple ligand specificity of the periplasmic lysine-, arginine-, ornithine-binding protein (see paper)
28% identity, 81% coverage of query (73.2 bits)
1lstA Three-dimensional structures of the periplasmic lysine-, arginine-, ornithine-binding protein with and without a ligand
28% identity, 81% coverage of query (73.2 bits)
1lahE Structural bases for multiple ligand specificity of the periplasmic lysine-, arginine-, ornithine-binding protein
28% identity, 81% coverage of query (73.2 bits)
1lagE Structural bases for multiple ligand specificity of the periplasmic lysine-, arginine-, ornithine-binding protein
28% identity, 81% coverage of query (73.2 bits)
ARGT_SALTY / P02911 Lysine/arginine/ornithine-binding periplasmic protein; LAO-binding protein from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 6 papers)
argT / RF|NP_461297.1 lysine/arginine/ornithine ABC transporter, periplasmic lysine/arginine/ornithine-binding protein ArgT from Salmonella enterica subsp. enterica serovar Typhimurium (see 4 papers)
28% identity, 81% coverage of query (72.8 bits)
Pf6N2E2_5402 ABC transporter for D-Alanine, periplasmic substrate-binding component from Pseudomonas fluorescens FW300-N2E2
26% identity, 81% coverage of query (72.4 bits)
Pf6N2E2_5660 L-Arginine ABC transporter, periplasmic substrate-binding component from Pseudomonas fluorescens FW300-N2E2
27% identity, 88% coverage of query (71.6 bits)
ArgT / b2310 lysine/arginine/ornithine ABC transporter periplasmic binding protein (EC 7.4.2.1) from Escherichia coli K-12 substr. MG1655 (see 6 papers)
TC 3.A.1.3.1 / TC 3.A.1.3.29 / P09551 ArgT aka B2310, component of Histidine/Arginine/Lysine (basic amino acid) uptake porter, HisJ/ArgT/HisP/HisM/HisQ [R, R, C, M, M, respectively] (Gilson et al. 1982). HisJ binds L-His (preferred), but 1-methyl-L-His and 3-methyl-L-His also bind, while the dipeptide carnosine binds weakly; D-histidine and the histidine degradation products, histamine, urocanic acid and imidazole do not bind. L-Arg, homo-L-Arg, and post-translationally modified methylated Arg-analogs also bind with the exception of symmetric dimethylated-L-Arg. L-Lys and L-Orn show weaker interactions with HisJ and methylated and acetylated Lys variants show poor binding.The carboxylate groups of these amino acids and their variants are essential from Escherichia coli (see 5 papers)
27% identity, 81% coverage of query (71.2 bits)
AO356_18700 L-Arginine ABC transporter, periplasmic substrate-binding component from Pseudomonas fluorescens FW300-N2C3
26% identity, 88% coverage of query (70.5 bits)
TC 3.A.1.3.18 / Q8YPM9 NatF, component of Acidic and neutral amino acid uptake transporter NatFGH/BgtA. BgtA is shared with BgtAB (see paper)
25% identity, 71% coverage of query (68.9 bits)
1hslA / P0AEU0 Refined 1.89 angstroms structure of the histidine-binding protein complexed with histidine and its relationship with many other active transport(slash)chemosensory receptors (see paper)
27% identity, 80% coverage of query (68.2 bits)
HISJ_SALTY / P02910 Histidine-binding periplasmic protein; HBP from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 4 papers)
hisJ / GB|AAV76512.1 histidine ABC transporter, periplasmic histidine-binding protein HisJ from Salmonella enterica subsp. enterica serovar Typhimurium (see 5 papers)
27% identity, 80% coverage of query (68.2 bits)
Pf1N1B4_3431 ABC transporter for L-Arginine and L-Citrulline, periplasmic substrate-binding component from Pseudomonas fluorescens FW300-N1B4
26% identity, 88% coverage of query (67.8 bits)
4g4pA / Q837S0 Crystal structure of glutamine-binding protein from enterococcus faecalis at 1.5 a (see paper)
29% identity, 75% coverage of query (67.4 bits)
3vvdA / Q72JG5 Crystal structure of ttc0807 complexed with ornithine (see paper)
26% identity, 86% coverage of query (67.0 bits)
Ac3H11_2555 ABC transporter for L-Histidine, periplasmic substrate-binding component 1 from Acidovorax sp. GW101-3H11
27% identity, 81% coverage of query (67.0 bits)
3vvfA Crystal structure of ttc0807 complexed with arginine
26% identity, 86% coverage of query (67.0 bits)
3vveA Crystal structure of ttc0807 complexed with lysine
26% identity, 86% coverage of query (67.0 bits)
TC 3.A.1.3.16 / Q0P9X8 PEB1A, component of Uptake system for glutamate and aspartate from Campylobacter jejuni (see 2 papers)
peb1A / RF|YP_002344319.1 major cell-binding factor from Campylobacter jejuni (see 3 papers)
peb1 / AAA02919.1 major cell-binding factor from Campylobacter jejuni (see paper)
24% identity, 85% coverage of query (66.6 bits)
3vv5A Crystal structure of ttc0807 complexed with (s)-2-aminoethyl-l- cysteine (aec)
26% identity, 84% coverage of query (66.6 bits)
2y7iA / Q8ZKA9 Structural basis for high arginine specificity in salmonella typhimurium periplasmic binding protein stm4351. (see paper)
26% identity, 77% coverage of query (66.2 bits)
GlnH / b0811 L-glutamine ABC transporter periplasmic binding protein (EC 7.4.2.1) from Escherichia coli K-12 substr. MG1655 (see 13 papers)
GlnH / P0AEQ3 L-glutamine ABC transporter periplasmic binding protein (EC 7.4.2.1) from Escherichia coli (strain K12) (see 13 papers)
GLNH_ECOLI / P0AEQ3 Glutamine-binding periplasmic protein; GlnBP from Escherichia coli (strain K12) (see paper)
TC 3.A.1.3.2 / P0AEQ3 Glutamine-binding periplasmic protein GlnH aka B0811 aka GlnBP, component of Three component ABC L-glutamine porter. The basal ATPase activity (ATP hydrolysis in the absence of substrate) is mainly caused by the docking of the closed-unliganded state of GlnH onto the transporter domain of GlnPQ. Unlike glutamine, arginine binds both GlnH domains, but does not trigger their closing. Comparison of the ATPase activity in nanodiscs with glutamine transport in proteoliposomes suggested that the stoichiometry of ATP per substrate is close to two from Escherichia coli (see 7 papers)
glnH / GB|AAN79369.1 glutamine ABC transporter, periplasmic glutamine-binding protein GlnH from Escherichia coli (see 7 papers)
24% identity, 78% coverage of query (66.2 bits)
2v25A / Q0P9X8 Structure of the campylobacter jejuni antigen peb1a, an aspartate and glutamate receptor with bound aspartate (see paper)
24% identity, 84% coverage of query (65.9 bits)
HisJ / b2309 histidine ABC transporter periplasmic binding protein (EC 7.4.2.1) from Escherichia coli K-12 substr. MG1655 (see 5 papers)
HISJ_ECOLI / P0AEU0 Histidine-binding periplasmic protein; HBP from Escherichia coli (strain K12) (see paper)
TC 3.A.1.3.29 / P0AEU0 Histidine-binding periplasmic protein, component of Histidine/Arginine/Lysine (basic amino acid) uptake porter, HisJ/ArgT/HisP/HisM/HisQ [R, R, C, M, M, respectively] (Gilson et al. 1982). HisJ binds L-His (preferred), but 1-methyl-L-His and 3-methyl-L-His also bind, while the dipeptide carnosine binds weakly; D-histidine and the histidine degradation products, histamine, urocanic acid and imidazole do not bind. L-Arg, homo-L-Arg, and post-translationally modified methylated Arg-analogs also bind with the exception of symmetric dimethylated-L-Arg. L-Lys and L-Orn show weaker interactions with HisJ and methylated and acetylated Lys variants show poor binding.The carboxylate groups of these amino acids and their variants are essential from Escherichia coli (strain K12)
hisJ / GB|AAC75369.1 histidine ABC transporter, periplasmic histidine-binding protein HisJ from Escherichia coli (see 7 papers)
26% identity, 80% coverage of query (65.5 bits)
AO353_03055 ABC transporter for L-Arginine and L-Citrulline, periplasmic substrate-binding component from Pseudomonas fluorescens FW300-N2E3
25% identity, 88% coverage of query (65.1 bits)
4ohnA / A0A0H2UKY8 Crystal structure of an abc uptake transporter substrate binding protein from streptococcus pneumoniae with bound histidine
22% identity, 85% coverage of query (65.1 bits)
4z9nB / A0A0M3KL33 Abc transporter / periplasmic binding protein from brucella ovis with glutathione bound
24% identity, 82% coverage of query (64.3 bits)
8eyzA / P0AEQ3 Engineered glutamine binding protein bound to gln and a cobaloxime ligand (see paper)
24% identity, 78% coverage of query (63.2 bits)
5l9oA Crystal structure of agrobacterium tumefaciens c58 strain pbp soca in complex with glucopine
25% identity, 84% coverage of query (62.4 bits)
5l9oB Crystal structure of agrobacterium tumefaciens c58 strain pbp soca in complex with glucopine
25% identity, 84% coverage of query (62.4 bits)
5lomB / Q7D447 Crystal structure of the pbp soca from agrobacterium tumefaciens c58 in complex with dfg at 1.5 a resolution (see paper)
25% identity, 84% coverage of query (62.4 bits)
2pyyB / D0VWX9 Crystal structure of the glur0 ligand-binding core from nostoc punctiforme in complex with (l)-glutamate (see paper)
26% identity, 73% coverage of query (59.7 bits)
6detA / S3MDF0 The crystal structure of tv2483 bound to l-arginine (see paper)
23% identity, 84% coverage of query (55.1 bits)
4zefA / Q837S0 Crystal structure of substrate binding domain 2 (sbd2) of abc transporter glnpq from enterococcus faecalis
25% identity, 73% coverage of query (52.4 bits)
3k4uE / Q7MAG0 Crystal structure of putative binding component of abc transporter from wolinella succinogenes dsm 1740 complexed with lysine
19% identity, 80% coverage of query (50.4 bits)
5itoA Structure of the periplasmic binding protein m117n-noct from a. Tumefaciens in complex with octopine
25% identity, 82% coverage of query (49.7 bits)
4i62A / A0A0H2ZN67 1.05 angstrom crystal structure of an amino acid abc transporter substrate-binding protein abpa from streptococcus pneumoniae canada mdr_19a bound to l-arginine
20% identity, 78% coverage of query (46.2 bits)
5orgA / P0A4F8 Structure of the periplasmic binding protein (pbp) occj from a. Tumefaciens b6 in complex with octopine. (see paper)
24% identity, 84% coverage of query (45.1 bits)
3tqlA / Q83E49 Structure of the amino acid abc transporter, periplasmic amino acid- binding protein from coxiella burnetii. (see paper)
24% identity, 77% coverage of query (45.1 bits)
4h5fA Crystal structure of an amino acid abc transporter substrate-binding protein from streptococcus pneumoniae canada mdr_19a bound to l- arginine, form 1
22% identity, 73% coverage of query (44.7 bits)
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Lawrence Berkeley National Laboratory