Searching for up to 100 curated homologs for BWI76_RS00580 FitnessBrowser__Koxy:BWI76_RS00580 (403 a.a.)
Found high-coverage hits (≥70%) to 74 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
BT2803 ribokinase (EC 2.7.1.15) from Bacteroides thetaiotaomicron VPI-5482
38% identity, 71% coverage of query (180 bits)
AO356_00950 Ribokinase (EC 2.7.1.15) from Pseudomonas fluorescens FW300-N2C3
40% identity, 75% coverage of query (172 bits)
BWI76_RS00290 Ribokinase (EC 2.7.1.15) from Klebsiella michiganensis M5al
37% identity, 75% coverage of query (165 bits)
AO353_20835 Ribokinase (EC 2.7.1.15) from Pseudomonas fluorescens FW300-N2E3
38% identity, 75% coverage of query (163 bits)
RBSK_STAAC / A0A0H2WZY4 Ribokinase; RK; EC 2.7.1.15 from Staphylococcus aureus (strain COL) (see paper)
A0A0H2WZY4 ribokinase (EC 2.7.1.15) from Staphylococcus aureus (see paper)
35% identity, 74% coverage of query (163 bits)
RBSKI_FRUSL / P83534 Bifunctional ribokinase/ribose-5-phosphate isomerase A; EC 2.7.1.15; EC 5.3.1.6 from Fructilactobacillus sanfranciscensis (strain ATCC 27651 / DSM 20451 / JCM 5668 / CCUG 30143 / KCTC 3205 / NCIMB 702811 / NRRL B-3934 / L-12) (Lactobacillus sanfranciscensis) (see paper)
37% identity, 72% coverage of query (159 bits)
deoK / Q8XGW5 deoxyribokinase monomer (EC 2.7.1.229) from Salmonella typhi (see 4 papers)
34% identity, 74% coverage of query (158 bits)
H281DRAFT_01116 deoxyribose kinase (EC 2.7.1.15) from Paraburkholderia bryophila 376MFSha3.1
35% identity, 74% coverage of query (152 bits)
BPHYT_RS25805 deoxyribose kinase (EC 2.7.1.15) from Burkholderia phytofirmans PsJN
34% identity, 75% coverage of query (148 bits)
6ilsB / A1A6H3 Structure of arabidopsis thaliana ribokinase complexed with ribose and atp (see paper)
34% identity, 73% coverage of query (147 bits)
RBSK / A1A6H3 ribokinase (EC 2.7.1.15) from Arabidopsis thaliana (see 2 papers)
RBSK_ARATH / A1A6H3 Ribokinase; AtRBSK; RK; EC 2.7.1.15 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
A1A6H3 ribokinase (EC 2.7.1.15) from Arabidopsis thaliana (see paper)
34% identity, 72% coverage of query (146 bits)
8cqxA / A0A0B0SD75 Ribokinase from t.Sp mutant a92g
35% identity, 71% coverage of query (141 bits)
RBSK_LEIMA / E9AD19 Ribokinase; RK; EC 2.7.1.15 from Leishmania major (see paper)
33% identity, 71% coverage of query (141 bits)
6a8aA / A0A3S7X0F5 Ribokinase from leishmania donovani with atp (see paper)
32% identity, 71% coverage of query (140 bits)
6a8cA Ribokinase from leishmania donovani with adp
32% identity, 71% coverage of query (140 bits)
6a8bA Ribokinase from leishmania donovani with amppcp
32% identity, 71% coverage of query (140 bits)
Q8NQR0 ribokinase (EC 2.7.1.15) from Corynebacterium glutamicum (see paper)
35% identity, 71% coverage of query (138 bits)
SMc01103 Ribokinase (EC 2.7.1.15) from Sinorhizobium meliloti 1021
33% identity, 74% coverage of query (138 bits)
RBSK_SCHPO / O60116 Ribokinase; RK; EC 2.7.1.15 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
32% identity, 72% coverage of query (134 bits)
HSERO_RS11500 Ribokinase (EC 2.7.1.15) from Herbaspirillum seropedicae SmR1
34% identity, 71% coverage of query (130 bits)
6znxC / A0A0B0SD75 Ribokinase from thermus species
31% identity, 71% coverage of query (106 bits)
Build an alignment for BWI76_RS00580 and 21 homologs with ≥ 30% identity
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RBSK_YEAST / P25332 Ribokinase; RK; EC 2.7.1.15 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 2 papers)
29% identity, 73% coverage of query (105 bits)
Q9YG89 6-phosphofructokinase (EC 2.7.1.11) from Aeropyrum pernix (see 2 papers)
29% identity, 73% coverage of query (90.9 bits)
TK2029 / Q5JDG9 α-D-ribose-1-phosphate 5-kinase (ADP) (EC 2.7.1.212) from Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (see paper)
R1PK_THEKO / Q5JDG9 ADP-dependent ribose-1-phosphate kinase; ADP-R1P kinase; ADP:alpha-D-ribose-1-phosphate 5-phosphotransferase; Alpha-D-ribose-1-phosphate 5-kinase (ADP); EC 2.7.1.212 from Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (Pyrococcus kodakaraensis (strain KOD1)) (see paper)
27% identity, 72% coverage of query (84.0 bits)
6xk2A / J9VQ51 Crystal structure of ribokinase from cryptococcus neoformans var. Grubii serotype a in complex with adp
28% identity, 74% coverage of query (79.3 bits)
7ag6A / P32143 Crystal structure of sf kinase yihv from e. Coli in complex with sulfofructose (sf), adp-mg (see paper)
28% identity, 74% coverage of query (77.0 bits)
SquV / b3883 6-deoxy-6-sulfofructose kinase (EC 2.7.1.184) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
yihV / P32143 6-deoxy-6-sulfofructose kinase (EC 2.7.1.184) from Escherichia coli (strain K12) (see 2 papers)
SQUV_ECOLI / P32143 Sulfofructose kinase; SF kinase; EC 2.7.1.184 from Escherichia coli (strain K12) (see 2 papers)
28% identity, 74% coverage of query (76.6 bits)
7agkA Crystal structure of e. Coli sf kinase (yihv) in complex with product sulfofructose phosphate (sfp)
28% identity, 74% coverage of query (76.6 bits)
7aghA Crystal structure of sf kinase yihv from e. Coli in complex with amppnp-mg
28% identity, 74% coverage of query (76.6 bits)
O04897 fructokinase (EC 2.7.1.4) from Solanum lycopersicum (see paper)
27% identity, 75% coverage of query (71.2 bits)
NK_METJA / Q57849 Nucleoside kinase; NK; ATP-dependent nucleoside monophosphokinase; Cytidine kinase; Guanosine-inosine kinase; EC 2.7.1.213; EC 2.7.1.73 from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii) (see 2 papers)
25% identity, 76% coverage of query (71.2 bits)
2c49A / Q57849 Crystal structure of methanocaldococcus jannaschii nucleoside kinase - an archaeal member of the ribokinase family (see paper)
25% identity, 75% coverage of query (70.5 bits)
P97328 ketohexokinase (EC 2.7.1.3) from Mus musculus (see 2 papers)
25% identity, 71% coverage of query (66.6 bits)
SCRK1_MAIZE / Q6XZ79 Fructokinase-1; ZmFRK1; EC 2.7.1.4 from Zea mays (Maize)
27% identity, 71% coverage of query (66.2 bits)
8omdA / P97328 Crystal structure of mkhk in complex with compound-4 (see paper)
25% identity, 71% coverage of query (65.9 bits)
6p2dA Structure of mouse ketohexokinasE-C in complex with fructose and adp
25% identity, 71% coverage of query (65.9 bits)
scrK / GB|AAA08602.1 fructokinase; EC 2.7.1.4 from Salmonella enterica subsp. enterica serovar Typhimurium (see paper)
scrK / CAA43323.1 fructokinase from Salmonella enterica subsp. enterica serovar Typhimurium (see paper)
25% identity, 72% coverage of query (64.7 bits)
SCRK1_ORYSI / A2WXV8 Fructokinase-1; Fructokinase I; OsFKI; EC 2.7.1.4 from Oryza sativa subsp. indica (Rice) (see paper)
26% identity, 71% coverage of query (63.2 bits)
8omeA / P50053 Crystal structure of hkhk-a in complex with compound-4 (see paper)
25% identity, 71% coverage of query (62.8 bits)
2hw1A Crystal structure of human ketohexokinase complexed to different sugar molecules
25% identity, 71% coverage of query (62.8 bits)
SCRK1_ORYSJ / Q0JGZ6 Fructokinase-1; Fructokinase I; OsFKI; EC 2.7.1.4 from Oryza sativa subsp. japonica (Rice) (see paper)
26% identity, 71% coverage of query (62.4 bits)
KHK_RAT / Q02974 Ketohexokinase; Hepatic fructokinase; EC 2.7.1.3 from Rattus norvegicus (Rat) (see 2 papers)
Q02974 ketohexokinase (EC 2.7.1.3) from Rattus norvegicus (see paper)
25% identity, 71% coverage of query (61.2 bits)
KHK / P50053 Ketohexokinase (EC 2.7.1.3) from Homo sapiens (see 8 papers)
KHK_HUMAN / P50053 Ketohexokinase; Hepatic fructokinase; EC 2.7.1.3 from Homo sapiens (Human) (see 4 papers)
P50053 ketohexokinase (EC 2.7.1.3) from Homo sapiens (see 6 papers)
25% identity, 71% coverage of query (60.5 bits)
6ul7A Structure of human ketohexokinasE-C in complex with fructose, no3, and osthole
25% identity, 71% coverage of query (60.5 bits)
8ug3A Crystal structure of khk-c and compound 23
25% identity, 71% coverage of query (60.5 bits)
8omkA Hkhk-c in complex with adp & fructose 1-phosphate
25% identity, 71% coverage of query (60.5 bits)
8ug1B / P50053 Crystal structure of khk-c and compound 13 (see paper)
25% identity, 71% coverage of query (60.1 bits)
3qa2A X-ray structure of ketohexokinase in complex with a pyrimidopyrimidine analog 2
25% identity, 71% coverage of query (60.1 bits)
8omfA Crystal structure of hkhk-c in complex with compound-4
25% identity, 71% coverage of query (60.1 bits)
6w0zA Structure of khk in complex with compound 8 (2-[(1~{s},5~{r})-3-[2- [(2~{s})-2-methylazetidin-1-yl]-6-(trifluoromethyl)pyrimidin-4-yl]-3- azabicyclo[3.1.0]hexan-6-yl]ethanoic acid)
25% identity, 71% coverage of query (60.1 bits)
6w0yA Structure of khk in complex with compound 6 (2-[(1~{r},5~{s})-3-[5- cyano-6-[(2~{s},3~{r})-2-methyl-3-oxidanyl-azetidin-1-yl]-4- (trifluoromethyl)pyridin-2-yl]-3-azabicyclo[3.1.0]hexan-6-yl]ethanoic acid)
25% identity, 71% coverage of query (60.1 bits)
6w0xA Structure of khk in complex with compound 4 (6-[(1~{s},5~{r})-6- (hydroxymethyl)-3-azabicyclo[3.1.0]hexan-3-yl]-2-[(2~{s},3~{r})-2- methyl-3-oxidanyl-azetidin-1-yl]-4-(trifluoromethyl)pyridine-3- carbonitrile)
25% identity, 71% coverage of query (60.1 bits)
6w0wA Structure of khk in complex with compound 3
25% identity, 71% coverage of query (60.1 bits)
6w0nA Structure of khk in complex with compound 2
25% identity, 71% coverage of query (60.1 bits)
5wbzA Structure of human ketohexokinase complexed with hits from fragment screening
25% identity, 71% coverage of query (60.1 bits)
5wbrA Structure of human ketohexokinase complexed with hits from fragment screening
25% identity, 71% coverage of query (60.1 bits)
5wbqA Structure of human ketohexokinase complexed with hits from fragment screening
25% identity, 71% coverage of query (60.1 bits)
5wbpA Structure of human ketohexokinase complexed with hits from fragment screening
25% identity, 71% coverage of query (60.1 bits)
5wboA Structure of human ketohexokinase complexed with hits from fragment screening
25% identity, 71% coverage of query (60.1 bits)
5wbmA Structure of human ketohexokinase complexed with hits from fragment screening
25% identity, 71% coverage of query (60.1 bits)
3ro4A X-ray structure of ketohexokinase in complex with an indazole compound derivative
25% identity, 71% coverage of query (60.1 bits)
3qaiA X-ray structure of ketohexokinase in complex with a pyrimidopyrimidine analog 3
25% identity, 71% coverage of query (60.1 bits)
3q92A X-ray structure of ketohexokinase in complex with a pyrimidopyrimidine analog 1
25% identity, 71% coverage of query (60.1 bits)
3ncaA X-ray structure of ketohexokinase in complex with a thieno pyridinol compound
25% identity, 71% coverage of query (60.1 bits)
3nc9A X-ray structure of ketohexokinase complexed with an indazole compound
25% identity, 71% coverage of query (60.1 bits)
3nc2A X-ray structure of ketohexokinase with a quinazoline
25% identity, 71% coverage of query (60.1 bits)
3nbwA X-ray structure of ketohexokinase in complex with a pyrazole compound
25% identity, 71% coverage of query (60.1 bits)
3nbvA X-ray structure of ketohexokinase in complex with amp-pnp and fructose
25% identity, 71% coverage of query (60.1 bits)
7c1zA Atp bound structure of pseudouridine kinase (puki) from arabidopsis thaliana
26% identity, 72% coverage of query (55.1 bits)
7w93A / A0A140N873 Crystal structure of e.Coli pseudouridine kinase psuk complexed with n1-methyl-pseudouridine (see paper)
24% identity, 73% coverage of query (53.9 bits)
7c1zB Atp bound structure of pseudouridine kinase (puki) from arabidopsis thaliana
25% identity, 72% coverage of query (53.5 bits)
7c1yA / Q94AT3 Pseudouridine and adp bound structure of pseudouridine kinase (puki) from arabidopsis thaliana (see paper)
25% identity, 72% coverage of query (53.5 bits)
STM4066 / Q8ZKR2 aminoimidazole riboside kinase (EC 2.7.1.223) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 2 papers)
AIRSK_SALTY / Q8ZKR2 Aminoimidazole riboside kinase; AIRs kinase; EC 2.7.1.223 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 2 papers)
Q8ZKR2 aminoimidazole riboside kinase (EC 2.7.1.223) from Salmonella enterica subsp. enterica serovar Typhimurium (see 2 papers)
24% identity, 75% coverage of query (50.8 bits)
PUKI_ARATH / Q94AT3 Pseudouridine kinase; EC 2.7.1.83 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
24% identity, 72% coverage of query (48.9 bits)
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Lawrence Berkeley National Laboratory