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Searching for up to 100 curated homologs for BWI76_RS01515 FitnessBrowser__Koxy:BWI76_RS01515 (105 a.a.)

Found high-coverage hits (≥70%) to 16 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

TC 4.A.3.2.9 / U5MLJ3 PTS lactose transporter subunit IIA, component of PTS-type lactose transporter, IIC-IIB-IIA from Klebsiella pneumoniae CG43
    97% identity, 100% coverage of query (209 bits)

TC 4.A.3.2.7 / C4X746 PEP-dependent phosphotransferase enzyme III, component of N,N'-diacetylchitobiose (cellobiose) PTS permease, CelABC (IIABC) from Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044
    48% identity, 94% coverage of query (105 bits)

TC 4.A.3.2.6 / Q9KSH3 VC_1283 aka IIA, component of Glucosamine β(1→4) glucosamine (GlcN)2 (glucosamine dimer) transporter, VC1281-1283 (IIB; IIC; IIA, respectively) from Vibrio cholerae (see paper)
    46% identity, 92% coverage of query (99.4 bits)

ChbA / b1736 N,N'-diacetylchitobiose-specific PTS enzyme IIA component (EC 2.7.1.196) from Escherichia coli K-12 substr. MG1655 (see 9 papers)
ChbA / P69791 N,N'-diacetylchitobiose-specific PTS enzyme IIA component (EC 2.7.1.196) from Escherichia coli (strain K12) (see 6 papers)
PTQA_ECOLI / P69791 PTS system N,N'-diacetylchitobiose-specific EIIA component; EIIA-Chb; EIII-Chb; IIIcel; N,N'-diacetylchitobiose-specific phosphotransferase enzyme IIA component from Escherichia coli (strain K12) (see 7 papers)
TC 4.A.3.2.1 / P69791 PTCA aka ChbA aka CELC aka B1736, component of N,N'-diacetylchitobiose (Chb) porter from Escherichia coli (see 9 papers)
    47% identity, 96% coverage of query (99.0 bits)

TC 4.A.3.2.8 / Q72XQ1 PTS system, cellobiose-specific IIA component, component of N-, N'-diacetylchitobiose PTS permease, IIABCChb from Bacillus cereus (strain ATCC 10987)
    40% identity, 100% coverage of query (95.1 bits)

TC 4.A.3.2.2 / P46319 PTCA aka LicA aka CELC, component of Lichenan oligosaccharide (Lic) porter from Bacillus subtilis (see 3 papers)
    41% identity, 96% coverage of query (87.4 bits)

Q45402 protein-Npi-phosphohistidine-cellobiose phosphotransferase (EC 2.7.1.205) from Geobacillus stearothermophilus (see paper)
    37% identity, 93% coverage of query (77.8 bits)

PTCA_LACLM / A2RIE7 PTS system galactose-specific EIIA component from Lactococcus lactis subsp. cremoris (strain MG1363) (see paper)
    37% identity, 95% coverage of query (76.6 bits)

PTCA_LACLA / Q9CIE9 PTS system cellobiose-specific EIIA component from Lactococcus lactis subsp. lactis (strain IL1403) (Streptococcus lactis) (see 2 papers)
TC 4.A.3.2.4 / Q9CIE9 PtcA, component of The cellobiose-specific (PtcA-PtcB-CelB) porter (Kowalczyk et al., 2008 ) from Lactococcus lactis subsp. lactis (Streptococcus lactis) (see paper)
    36% identity, 95% coverage of query (75.5 bits)

PTLA_LACLL / P23532 PTS system lactose-specific EIIA component; EIIA-Lac; EIII-Lac; Lactose-specific phosphotransferase enzyme IIA component from Lactococcus lactis subsp. lactis (Streptococcus lactis) (see 2 papers)
    35% identity, 94% coverage of query (72.0 bits)

PTLA_STAAU / P0A0D6 PTS system lactose-specific EIIA component; EIIA-Lac; EIII-Lac; Lactose-specific phosphotransferase enzyme IIA component from Staphylococcus aureus (see 8 papers)
TC 4.A.3.1.1 / P0A0D6 PtlA aka LACF, component of Lactose (Lac) porter, LacEF from Staphylococcus aureus (see 5 papers)
    33% identity, 94% coverage of query (68.2 bits)

PTLA_LACCA / P11502 PTS system lactose-specific EIIA component; EIIA-Lac; EIII-Lac; FIII-Lac; Lactose-specific phosphotransferase enzyme IIA component from Lacticaseibacillus casei (Lactobacillus casei) (see paper)
    35% identity, 96% coverage of query (67.8 bits)

TC 4.A.3.1.2 / Q045X4 PTS system lactose-specific IIA component, Lac family, component of Lactose PTS group translocator #1, IIA/IICB from Lactobacillus gasseri (strain ATCC 33323 / DSM 20243)
    32% identity, 94% coverage of query (61.6 bits)

TC 4.A.3.1.3 / Q045H4 Cellobiose-specific PTS system IIA component, component of Lactose PTS group translocator #2, IIA/IICB from Lactobacillus gasseri (strain ATCC 33323 / DSM 20243)
    31% identity, 87% coverage of query (56.2 bits)

Build an alignment

Build an alignment for BWI76_RS01515 and 14 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Additional hits (identity < 30%)

PTEA_BACSU / O05506 PTS system oligo-beta-mannoside-specific EIIA component; Glucomannan utilization protein A; Oligo-beta-mannoside-specific phosphotransferase enzyme IIA component from Bacillus subtilis (strain 168) (see paper)
    26% identity, 90% coverage of query (52.4 bits)

TC 4.A.3.2.3 / O50981 ChbA, component of N,N'-diacetylchitobiose porter, ChbABC from Borrelia burgdorferi (Lyme disease spirochete) (see paper)
    28% identity, 95% coverage of query (45.8 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory