Searching for up to 100 curated homologs for BWI76_RS01735 FitnessBrowser__Koxy:BWI76_RS01735 (164 a.a.)
Found high-coverage hits (≥70%) to 24 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
PTRB_KLEPN / P37081 PTS system sorbose-specific EIIB component; EIIB-Sor; EIII-B-Sor; Sorbose-specific phosphotransferase enzyme IIB component; EC 2.7.1.206 from Klebsiella pneumoniae (see 3 papers)
TC 4.A.6.1.3 / P37081 PTRB aka SORB, component of Sorbose porter from Klebsiella pneumoniae (see 3 papers)
89% identity, 100% coverage of query (301 bits)
PTRB_LACCA / Q9RGG4 PTS system sorbose-specific EIIB component; EIIB-Sor; Sorbose-specific phosphotransferase enzyme IIB component; EC 2.7.1.206 from Lacticaseibacillus casei (Lactobacillus casei) (see paper)
Q9RGG4 protein-Npi-phosphohistidine-L-sorbose phosphotransferase (subunit 3/4) (EC 2.7.1.206) from Lacticaseibacillus casei (see paper)
65% identity, 97% coverage of query (221 bits)
TC 4.A.6.1.16 / Q8Y8V9 Lmo0783 protein, component of Constitutively synthesized sensor, MpoABCD, controlling man operon (see TC# 4.A.6.1.15) expression by interacting with and phosphorylating ManR, the transcriptional regulator of the man operon from Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e)
58% identity, 94% coverage of query (189 bits)
ManX / b1817 mannose-specific PTS enzyme IIAB component (EC 2.7.1.191; EC 2.7.1.199; EC 2.7.1.193) from Escherichia coli K-12 substr. MG1655 (see 12 papers)
manX / P69797 mannose-specific PTS enzyme IIAB component from Escherichia coli (strain K12) (see 9 papers)
PTNAB_ECOLI / P69797 PTS system mannose-specific EIIAB component; EIIAB-Man; EIII-Man; EC 2.7.1.191 from Escherichia coli (strain K12) (see 10 papers)
TC 4.A.6.1.1 / P69797 PTNA aka MANX aka PTSL aka GPTB aka B1817, component of The mannose (glucose, 2-deoxyglucose, glucosamine, N-acetylglucosamine, N-acetylmannosamine, mannosamine and fructose) PTS porter/group translocator, ManXYZ (Rephaeli and Saier 1980; Plumbridge 2015). Catalyzes xylose facilitated diffusion in lactobacilli. The order of D-sugar substrate affinities is: glucose > mannose > 2-deoxyglucose > N-acetylglucosamine > glucosamine > N-acetylmannosamine > mannosamine > fructose from Escherichia coli (see 10 papers)
manX / RF|NP_416331.1 PTS system mannose-specific EIIAB component; EC 2.7.1.-; EC 2.7.1.69 from Escherichia coli K12 (see 10 papers)
52% identity, 97% coverage of query (176 bits)
PTFB_BACSU / P26380 PTS system fructose-specific EIIB component; EIIB-Fru; Fructose-specific phosphotransferase enzyme IIB component; lev-PTS; p18; EC 2.7.1.202 from Bacillus subtilis (strain 168) (see 3 papers)
TC 4.A.6.1.2 / P26380 PTFB aka LEVE aka SACL, component of Fructose group translocator, LevDEFG from Bacillus subtilis (see 4 papers)
46% identity, 91% coverage of query (154 bits)
TC 4.A.6.1.11 / D2BKY7 Mannose-specificPTS system, IIAB component, component of Mannose enzyme II complex, IIAB, IIC, IID. IIC/IID serve allows entry of some bacteriocins including pediocin (class IIa) and lactococcin A (class IIc) (Kjos et al., 2011). Transports and phosphorylates Glucose, Mannose and Glucosamine from Lactococcus lactis subsp. lactis (strain KF147) (see 2 papers)
43% identity, 96% coverage of query (143 bits)
TC 4.A.6.1.10 / Q04GK1 Phosphotransferase system, mannose/fructose-specific component IIA, component of The hexose (glucose and fructose demonstrated) PTS uptake system from Oenococcus oeni (strain BAA-331 / PSU-1) (see paper)
42% identity, 91% coverage of query (135 bits)
TC 4.A.6.1.15 / E1UCI0 PTS system, mannose-specific, IIAB component, component of The primary glucose /mannose uptake transporter, ManLMN from Listeria monocytogenes serotype 4a (strain L99)
40% identity, 100% coverage of query (134 bits)
Q9S4L5 protein-Npi-phosphohistidine-D-mannose phosphotransferase (EC 2.7.1.191) from Streptococcus salivarius (see paper)
40% identity, 99% coverage of query (132 bits)
TC 4.A.6.1.7 / Q5M5W6 ManL, component of The glucose/mannose/2-deoxyglucose/fructose phosphotransferase systems (phosphorylates without transport), ManLMN from Streptococcus thermophilus (strain ATCC BAA-250 / LMG 18311) (see paper)
40% identity, 99% coverage of query (130 bits)
TC 4.A.6.1.6 / Q2QKM4 ManL aka EIIAB, component of Glucose porter, ManLMN from Lactobacillus casei (see paper)
38% identity, 93% coverage of query (114 bits)
TC 4.A.6.1.18 / B3W754 Phosphotransferase system sugar-specific EIIB component, component of Uptake porter/group translocator of galacto N-biose (Gal-β-1,3-GalNAc: galactose linked β-1,3 to N-acetylgalactosamine), lacto N-biose (Gal-β-1,3-GlcNAc: galactose linked β-1,3 to N-acetylglucosamine), and D-N-acetylgalactosamine (Bidart et al. 2014). The system is designated the GnbABCD system where GnbA = IIA, GnbB = IIB, GnbC = IIC, and GnbD = IID of the mannose-type PTS Enzyme II complex from Lactobacillus casei (strain BL23)
32% identity, 94% coverage of query (103 bits)
TC 4.A.6.1.4 / Q9KIQ4 AgaV, component of N-acetyl galactosamine (GalNAc or Aga) porter (used the same IIA protein (AgaF) as does 4.A.6.1.5) from Escherichia coli (see paper)
35% identity, 93% coverage of query (102 bits)
YhaY / b3133 N-acetyl-D-galactosamine specific PTS enzyme IIB component from Escherichia coli K-12 substr. MG1655 (see 3 papers)
35% identity, 93% coverage of query (102 bits)
TC 4.A.6.1.9 / Q97N92 PTS system, IIB component, component of The fucose PTS uptake transporter, IIA/IIB/IIC/IIDFuc (FcsABCD) (Manzoor et al. 2015). Expression in response to fucose is under the control of the FcsR transcriptional activator, and its DNA binding site has been identified from Streptococcus pneumoniae (see paper)
32% identity, 96% coverage of query (98.2 bits)
TC 4.A.6.1.13 / B3WB09 Phosphoenolpyruvate-dependent sugar phosphotransferase system EIIAB, probable mannose specific, component of Fucosyl-α-1,3-N-acetylglucosamine PTS uptake porter, AlfEFG (next to an operon encoding a fucosidase (AlfB) and a transcriptional regulator of the GntR family, AlfR) from Lactobacillus casei (strain BL23)
33% identity, 88% coverage of query (94.7 bits)
TC 4.A.6.1.25 / CAQ67973.1 CAQ67973.1 AhaB protein (Fragment), component of D-ribitol (D-aldonitol) (a pentitol) PTS Enzyme II complex RtlABCD from Lactobacillus casei BL23
32% identity, 92% coverage of query (94.0 bits)
TC 4.A.6.1.14 / Q8DR76 Phosphotransferase system sugar-specific EII component, component of Probable PTS uptake porter (IIA - IID) of disaccharides of gluconate and N-acetyglucosamine derived from degradation of hyaluronate and chondroitin by hyaluronidase (Marion et al. 2012). The cytoplasmic disaccharide may be hydrolyzed by the enzyme Ugl from Streptococcus pneumoniae (strain ATCC BAA-255 / R6)
35% identity, 82% coverage of query (90.9 bits)
dgaB / A0A0F6B8S7 D-glucosaminate PTS permease components EIIB (EC 2.7.1.203) from Salmonella typhimurium (strain 14028s / SGSC 2262) (see paper)
TC 4.A.6.1.17 / D0ZLR6 Putative phosphotransferase system enzyme IIB, component of D-glucosaminate group translocating uptake porter, DgaABCD (IIA-141 aas, IIB-161 aas, IIC-249 aas, and IID-285 aas, respectively) from Salmonella typhimurium (strain 14028s / SGSC 2262)
32% identity, 95% coverage of query (90.1 bits)
Build an alignment for BWI76_RS01735 and 19 homologs with ≥ 30% identity
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gfrB / A0A0F6BB78 fructoselysine/glucoselysine PTS enzyme IIB component from Salmonella typhimurium (strain 14028s / SGSC 2262) (see paper)
TC 4.A.6.1.19 / V7IFY8 PTS system sorbose subfamily IIB component, component of PTS uptake system for glucoselysine and fructoselysine, GfrABCD from Salmonella enterica subsp. enterica serovar Cubana str. 76814
29% identity, 89% coverage of query (88.6 bits)
Y801_STRP6 / Q5XCC7 Probable phosphotransferase enzyme IIB component M6_Spy0801; PTS system EIIB component; EC 2.7.1.- from Streptococcus pyogenes serotype M6 (strain ATCC BAA-946 / MGAS10394)
27% identity, 82% coverage of query (76.3 bits)
AgaB / b3138 galactosamine-specific PTS enzyme IIB component from Escherichia coli K-12 substr. MG1655 (see 2 papers)
TC 4.A.6.1.5 / P42909 PTPB aka AgaB aka B3138, component of Galactosamine (GalN or Gam) porter (used the same IIA protein (AgaF) as does 4.A.6.1.4) from Escherichia coli (see 4 papers)
31% identity, 94% coverage of query (72.4 bits)
agaB / Q8XAB8 AgaB (EC 2.7.1.193) from Escherichia coli O157:H7 (see 4 papers)
31% identity, 94% coverage of query (72.4 bits)
TC 4.A.6.1.8 / Q82ZC7 PTS system, IIB component, component of The gluconate PTS uptake system. IIAGnt and IIBGnt form a high affinity 2:2 heterotetrameric complex from Enterococcus faecalis (see paper)
31% identity, 82% coverage of query (67.8 bits)
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Lawrence Berkeley National Laboratory