Searching for up to 100 curated homologs for BWI76_RS03090 FitnessBrowser__Koxy:BWI76_RS03090 (646 a.a.)
Found high-coverage hits (≥70%) to 100 curated proteins.
Removed hits that are identical to the query, leaving 99
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
AO353_21360 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase IolD (EC 3.7.1.22) from Pseudomonas fluorescens FW300-N2E3
72% identity, 100% coverage of query (941 bits)
AO356_23185 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase IolD (EC 3.7.1.22) from Pseudomonas fluorescens FW300-N2C3
72% identity, 100% coverage of query (938 bits)
Pf6N2E2_517 Epi-inositol hydrolase (EC 3.7.1.-) from Pseudomonas fluorescens FW300-N2E2
72% identity, 100% coverage of query (931 bits)
Pf1N1B4_4279 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase IolD (EC 3.7.1.22) from Pseudomonas fluorescens FW300-N1B4
72% identity, 100% coverage of query (930 bits)
PS417_11870 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase IolD (EC 3.7.1.22) from Pseudomonas simiae WCS417
71% identity, 100% coverage of query (928 bits)
iolD / P42415 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase (EC 3.7.1.22) from Bacillus subtilis (strain 168) (see 2 papers)
IOLD_BACSU / P42415 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase; THcHDO hydrolase; EC 3.7.1.22 from Bacillus subtilis (strain 168) (see paper)
P42415 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione acylhydrolase (ring-opening) (EC 3.7.1.22) from Bacillus subtilis (see paper)
54% identity, 100% coverage of query (738 bits)
Q9L3I0 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione acylhydrolase (ring-opening) (EC 3.7.1.22) from Rhizobium leguminosarum (see paper)
44% identity, 100% coverage of query (508 bits)
HSERO_RS12130 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase IolD (EC 3.7.1.22) from Herbaspirillum seropedicae SmR1
44% identity, 99% coverage of query (498 bits)
SMc01166 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase IolD (EC 3.7.1.22) from Sinorhizobium meliloti 1021
44% identity, 100% coverage of query (497 bits)
PGA1_c07250 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase IolD (EC 3.7.1.22) from Phaeobacter inhibens BS107
38% identity, 99% coverage of query (408 bits)
Build an alignment for BWI76_RS03090 and 10 homologs with ≥ 30% identity
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Q8U2A4 acetolactate synthase (EC 2.2.1.6) from Pyrococcus furiosus (see paper)
27% identity, 93% coverage of query (191 bits)
P42463 acetolactate synthase (EC 2.2.1.6) from Corynebacterium glutamicum (see paper)
28% identity, 91% coverage of query (172 bits)
P45261 acetolactate synthase (EC 2.2.1.6) from Haemophilus influenzae (see paper)
26% identity, 89% coverage of query (152 bits)
ilvB / AAB38426.1 acetolactate synthase from Mycobacterium avium (see paper)
27% identity, 91% coverage of query (152 bits)
thzk0150 / BAO66169.1 2-hydroxy-4-methyl-2-(2-phenylacetyl)pentanoic acid synthase from Thermosporothrix hazakensis (see paper)
26% identity, 89% coverage of query (151 bits)
ILVB1_MYCTU / P9WG41 Acetolactate synthase large subunit IlvB1; ALS; Acetohydroxy-acid synthase large subunit; AHAS; EC 2.2.1.6 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 4 papers)
P9WG41 acetolactate synthase (subunit 2/2) (EC 2.2.1.6) from Mycobacterium tuberculosis (see paper)
27% identity, 91% coverage of query (149 bits)
ilvB / O08353 acetohydroxy-acid synthase large subunit (EC 2.2.1.6) from Methanococcus aeolicus (see 2 papers)
25% identity, 93% coverage of query (148 bits)
Q5S3P7 acetolactate synthase (EC 2.2.1.6) from Streptomyces cinnamonensis (see 2 papers)
ilvB / AAV52901.1 acetohydroxy acid synthase large subunit from Streptomyces cinnamonensis (see paper)
25% identity, 96% coverage of query (146 bits)
P37251 acetolactate synthase (EC 2.2.1.6) from Bacillus subtilis (see paper)
25% identity, 88% coverage of query (144 bits)
ILVG_ECOLI / P0DP90 Acetolactate synthase isozyme 2 large subunit; AHAS-II; ALS-II; Acetohydroxy-acid synthase II large subunit; EC 2.2.1.6 from Escherichia coli (strain K12) (see 2 papers)
ilvG / GB|CAA28573.1 acetolactate synthase isozyme 2 large subunit; EC 2.2.1.6 from Escherichia coli K12 (see 8 papers)
26% identity, 89% coverage of query (141 bits)
Q8RL88 acetolactate synthase (subunit 2/2) (EC 2.2.1.6) from Geobacillus stearothermophilus (see paper)
ilvB / AAL99356.1 acetohydroxy acid synthase large subunit from Geobacillus stearothermophilus (see paper)
26% identity, 88% coverage of query (140 bits)
IlvB / b3671 acetohydroxy acid synthase I subunit IlvB (EC 2.2.1.6) from Escherichia coli K-12 substr. MG1655 (see 7 papers)
ilvB / P08142 acetohydroxy acid synthase I subunit IlvB (EC 2.2.1.6) from Escherichia coli (strain K12) (see 4 papers)
P08142 acetolactate synthase (subunit 2/2) (EC 2.2.1.6) from Escherichia coli (see paper)
24% identity, 93% coverage of query (139 bits)
IlvI / b0077 acetolactate synthase / acetohydroxybutanoate synthase, catalytic subunit (EC 2.2.1.6) from Escherichia coli K-12 substr. MG1655 (see 9 papers)
ilvI / P00893 acetolactate synthase / acetohydroxybutanoate synthase, catalytic subunit (EC 2.2.1.6) from Escherichia coli (strain K12) (see 7 papers)
P00893 acetolactate synthase (subunit 2/2) (EC 2.2.1.6) from Escherichia coli (see paper)
27% identity, 78% coverage of query (138 bits)
1t9bA / P07342 Crystal structure of yeast acetohydroxyacid synthase in complex with a sulfonylurea herbicide, chlorsulfuron (see paper)
25% identity, 89% coverage of query (137 bits)
Q5SJ01 acetolactate synthase (EC 2.2.1.6); pyruvate decarboxylase (EC 4.1.1.1) from Thermus thermophilus (see paper)
26% identity, 89% coverage of query (137 bits)
1t9dB Crystal structure of yeast acetohydroxyacid synthase in complex with a sulfonylurea herbicide, metsulfuron methyl
25% identity, 89% coverage of query (137 bits)
6lpiB / P08142 Crystal structure of ahas holo-enzyme (see paper)
25% identity, 88% coverage of query (135 bits)
1t9cA Crystal structure of yeast acetohydroxyacid synthase in complex with a sulfonylurea herbicide, sulfometuron methyl
25% identity, 89% coverage of query (134 bits)
1t9aA Crystal structure of yeast acetohydroxyacid synthase in complex with a sulfonylurea herbicide, tribenuron methyl
25% identity, 89% coverage of query (134 bits)
1t9dA Crystal structure of yeast acetohydroxyacid synthase in complex with a sulfonylurea herbicide, metsulfuron methyl
25% identity, 89% coverage of query (134 bits)
K7TWQ8 acetolactate synthase (EC 2.2.1.6) from Zea mays (see paper)
26% identity, 90% coverage of query (133 bits)
A0A0M3TGF7 acetolactate synthase (EC 2.2.1.6) from Poa annua (see paper)
25% identity, 90% coverage of query (133 bits)
6u9dB / P07342 Saccharomyces cerevisiae acetohydroxyacid synthase (see paper)
25% identity, 89% coverage of query (133 bits)
A5X300 acetolactate synthase (EC 2.2.1.6) from Oryza sativa Indica Group (see paper)
24% identity, 90% coverage of query (132 bits)
ILVB_YEAST / P07342 Acetolactate synthase catalytic subunit, mitochondrial; Acetohydroxy-acid synthase catalytic subunit; AHAS; ALS; EC 2.2.1.6 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 2 papers)
P07342 acetolactate synthase (EC 2.2.1.6) from Saccharomyces cerevisiae (see 5 papers)
25% identity, 89% coverage of query (132 bits)
A0A0M4NDK0 acetolactate synthase (EC 2.2.1.6) from Poa annua (see paper)
25% identity, 90% coverage of query (132 bits)
SYNPCC7002_A2770 / B1XMM5 2-oxoglutarate decarboxylase monomer (EC 4.1.1.71) from Synechococcus sp. (strain ATCC 27264 / PCC 7002 / PR-6) (see 2 papers)
B1XMM5 oxoglutarate dehydrogenase (succinyl-transferring) (EC 1.2.4.2) from Synechococcus sp. PCC 7002 (see paper)
24% identity, 93% coverage of query (132 bits)
5wkcA Saccharomyces cerevisiae acetohydroxyacid synthase in complex with the herbicide penoxsulam
25% identity, 89% coverage of query (132 bits)
1t9bB Crystal structure of yeast acetohydroxyacid synthase in complex with a sulfonylurea herbicide, chlorsulfuron
25% identity, 89% coverage of query (132 bits)
PS417_08810 glyoxylate carboligase (EC 4.1.1.47) from Pseudomonas simiae WCS417
26% identity, 81% coverage of query (131 bits)
ilvB / Q0KCU4 acetohydroxyacid synthase subunit B (EC 2.2.1.6) from Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier 337) (see paper)
25% identity, 84% coverage of query (131 bits)
1n0hA Crystal structure of yeast acetohydroxyacid synthase in complex with a sulfonylurea herbicide, chlorimuron ethyl
25% identity, 89% coverage of query (131 bits)
V5Q0Z4 acetolactate synthase (EC 2.2.1.6) from Myosoton aquaticum (see paper)
25% identity, 90% coverage of query (130 bits)
G0ZSE6 acetolactate synthase (EC 2.2.1.6) from Pseudomonas sp. (see paper)
25% identity, 91% coverage of query (130 bits)
Q6K2E8 acetolactate synthase (EC 2.2.1.6) from Oryza sativa (see paper)
24% identity, 90% coverage of query (129 bits)
ilvB / AAA93098.1 acetolactate synthase from Streptomyces avermitilis (see paper)
25% identity, 81% coverage of query (129 bits)
8i07D Crystal structure of escherichia coli glyoxylate carboligase double mutant in complex with glycolaldehyde
26% identity, 87% coverage of query (125 bits)
8i07A Crystal structure of escherichia coli glyoxylate carboligase double mutant in complex with glycolaldehyde
26% identity, 87% coverage of query (125 bits)
5imsA Saccharomyces cerevisiae acetohydroxyacid synthase
24% identity, 88% coverage of query (124 bits)
Q5VB42 acetolactate synthase (EC 2.2.1.6) from Helianthus annuus (see paper)
25% identity, 78% coverage of query (123 bits)
Psest_1181 Glyoxylate carboligase (EC 4.1.1.47) from Pseudomonas stutzeri RCH2
25% identity, 84% coverage of query (123 bits)
Gcl / b0507 glyoxylate carboligase (EC 4.1.1.47) from Escherichia coli K-12 substr. MG1655 (see 7 papers)
gcl / P0AEP7 glyoxylate carboligase (EC 4.1.1.47) from Escherichia coli (strain K12) (see 6 papers)
P0AEP7 tartronate-semialdehyde synthase (EC 4.1.1.47) from Escherichia coli K-12 (see paper)
gcl / ECOCYC|GLYOCARBOLIG-MONOMER glyoxylate carboligase; EC 4.1.1.47 from Escherichia coli K12 (see 5 papers)
gcl / AAA23864.1 glyoxylate carboligase from Escherichia coli (see paper)
26% identity, 87% coverage of query (123 bits)
7tzzA Crystal structure of arabidopsis thaliana acetohydroxyacid synthase p197t mutant in complex with bispyribac-sodium
24% identity, 92% coverage of query (123 bits)
8beoB Crystal structure of e. Coli glyoxylate carboligase mutant i393a with map
25% identity, 87% coverage of query (123 bits)
8beoA Crystal structure of e. Coli glyoxylate carboligase mutant i393a with map
25% identity, 87% coverage of query (123 bits)
5k2oA / P17597 Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with a pyrimidinyl-benzoate herbicide, pyrithiobac (see paper)
24% identity, 92% coverage of query (122 bits)
ILVB_ARATH / P17597 Acetolactate synthase, chloroplastic; AtALS; Acetohydroxy-acid synthase; Protein CHLORSULFURON RESISTANT 1; EC 2.2.1.6 from Arabidopsis thaliana (Mouse-ear cress) (see 16 papers)
P17597 acetolactate synthase (EC 2.2.1.6) from Arabidopsis thaliana (see 8 papers)
24% identity, 92% coverage of query (122 bits)
ILVB2_MYCTU / O06335 Putative acetolactate synthase large subunit IlvB2; ALS; Acetohydroxy-acid synthase large subunit; AHAS; EC 2.2.1.6 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
O06335 acetolactate synthase (EC 2.2.1.6) from Mycobacterium tuberculosis (see paper)
25% identity, 86% coverage of query (122 bits)
8et4A Crystal structure of wild-type arabidopsis thaliana acetohydroxyacid synthase in complex with amidosulfuron
24% identity, 92% coverage of query (122 bits)
5wj1A Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with a triazolopyrimidine herbicide, penoxsulam
24% identity, 92% coverage of query (122 bits)
5k6tA Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with a sulfonylamino-carbonyl-triazolinone herbicide, propoxycarbazone-sodium
24% identity, 92% coverage of query (122 bits)
5k6rA Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with a sulfonylamino-carbonyl-triazolinone herbicide, thiencarbazone-methyl
24% identity, 92% coverage of query (122 bits)
1z8nA Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with an imidazolinone herbicide, imazaquin
24% identity, 92% coverage of query (122 bits)
1yi1A Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with a sulfonylurea herbicide, tribenuron methyl
24% identity, 92% coverage of query (122 bits)
1yi0A Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with a sulfonylurea herbicide, sulfometuron methyl
24% identity, 92% coverage of query (122 bits)
1yhzA Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with a sulfonylurea herbicide, chlorsulfuron
24% identity, 92% coverage of query (122 bits)
1yhyA Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with a sulfonylurea herbicide, metsulfuron methyl
24% identity, 92% coverage of query (122 bits)
1ybhA Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with a sulfonylurea herbicide chlorimuron ethyl
24% identity, 92% coverage of query (122 bits)
P09114 Acetolactate synthase 2, chloroplastic; ALS II; Acetohydroxy-acid synthase II; Acetolactate synthase II; EC 2.2.1.6 from Nicotiana tabacum (Common tobacco)
24% identity, 90% coverage of query (122 bits)
5k3sA Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with a pyrimidinyl-benzoate herbicide, bispyribac-sodium
24% identity, 92% coverage of query (122 bits)
6bd3A Saccharomyces cerevisiae acetohydroxyacid synthase
24% identity, 87% coverage of query (122 bits)
8i01A / P0AEP7 Crystal structure of escherichia coli glyoxylate carboligase (see paper)
25% identity, 87% coverage of query (121 bits)
P09342 Acetolactate synthase 1, chloroplastic; ALS I; Acetohydroxy-acid synthase I; Acetolactate synthase I; EC 2.2.1.6 from Nicotiana tabacum (Common tobacco)
24% identity, 92% coverage of query (121 bits)
3ea4A Arabidopsis thaliana acetohydroxyacid synthase in complex with monosulfuron-ester
24% identity, 92% coverage of query (121 bits)
3e9yA Arabidopsis thaliana acetohydroxyacid synthase in complex with monosulfuron
24% identity, 92% coverage of query (121 bits)
1jscA Crystal structure of the catalytic subunit of yeast acetohydroxyacid synthase: a target for herbicidal inhibitors
24% identity, 87% coverage of query (121 bits)
Q42768 acetolactate synthase (EC 2.2.1.6) from Gossypium hirsutum (see paper)
24% identity, 91% coverage of query (120 bits)
6bd9A Saccharomyces cerevisiae acetohydroxyacid synthase
24% identity, 87% coverage of query (120 bits)
6dekA Crystal structure of candida albicans acetohydroxyacid synthase catalytic subunit
23% identity, 92% coverage of query (113 bits)
6denA Crystal structure of candida albicans acetohydroxyacid synthase in complex with the herbicide iodomuron ethyl
23% identity, 92% coverage of query (112 bits)
6deoA Crystal structure of candida albicans acetohydroxyacid synthase in complex with the herbicide iodomuron methyl
23% identity, 92% coverage of query (111 bits)
6desA Crystal structure of candida albicans acetohydroxyacid synthase in complex with the herbicide propoxycarbazone
23% identity, 92% coverage of query (111 bits)
6depA Crystal structure of candida albicans acetohydroxyacid synthase in complex with the herbicide sulfometuron methyl
23% identity, 92% coverage of query (111 bits)
6derA Crystal structure of candida albicans acetohydroxyacid synthase in complex with the herbicide metosulam
23% identity, 92% coverage of query (111 bits)
6demA Crystal structure of candida albicans acetohydroxyacid synthase in complex with the herbicide bensulfuron methyl
23% identity, 92% coverage of query (110 bits)
6delA Crystal structure of candida albicans acetohydroxyacid synthase in complex with the herbicide chlorimuron ethyl
23% identity, 92% coverage of query (110 bits)
6deqA / A0A1D8PJF9 Crystal structure of candida albicans acetohydroxyacid synthase in complex with the herbicide penoxsulam (see paper)
23% identity, 92% coverage of query (108 bits)
6vz8D / P17597 Arabidopsis thaliana acetohydroxyacid synthase complex with valine bound (see paper)
23% identity, 90% coverage of query (104 bits)
7pt1A Actinobacterial 2-hydroxyacyl-coa lyase (achacl) structure in complex with substrate 2-hib-coa and inactive cofactor 3-deaza-thdp
25% identity, 82% coverage of query (104 bits)
7pt4B / P0DUV9 Actinobacterial 2-hydroxyacyl-coa lyase (achacl) structure in complex with a covalently bound reaction intermediate as well as products formyl-coa and acetone (see paper)
25% identity, 82% coverage of query (104 bits)
HACL_ACTC0 / P0DUV9 2-hydroxyacyl-CoA lyase; AcHACL; HACL; 2-hydroxyisobutyryl-CoA lyase; EC 4.1.-.- from Actinomycetospora chiangmaiensis (strain DSM 45062 / JCM 15998 / CCTCC AA 205017 / NBRC 104400 / YIM 0006) (see 2 papers)
25% identity, 82% coverage of query (104 bits)
7pt4A Actinobacterial 2-hydroxyacyl-coa lyase (achacl) structure in complex with a covalently bound reaction intermediate as well as products formyl-coa and acetone
25% identity, 82% coverage of query (104 bits)
8rpjA Janthe from janthinobacterium sp. Hh01
23% identity, 90% coverage of query (101 bits)
8rpiA Janthe from janthinobacterium sp. Hh01, lactyl-thdp
23% identity, 90% coverage of query (101 bits)
8rphD 8rphD
23% identity, 90% coverage of query (101 bits)
6wo1A / Q96VZ6 Hybrid acetohydroxyacid synthase complex structure with cryptococcus neoformans ahas catalytic subunit and saccharomyces cerevisiae ahas regulatory subunit (see paper)
24% identity, 77% coverage of query (100 bits)
4d5eB / P0CH62 Crystal structure of recombinant wildtype cdh (see paper)
24% identity, 71% coverage of query (94.0 bits)
2pgnA The crystal structure of fad and thdp-dependent cyclohexane-1,2-dione hydrolase in complex with cyclohexane-1,2-dione
24% identity, 71% coverage of query (94.0 bits)
4feeA High-resolution structure of pyruvate oxidase in complex with reaction intermediate 2-hydroxyethyl-thiamin diphosphate carbanion-enamine, crystal b (see paper)
21% identity, 87% coverage of query (93.6 bits)
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