Searching for up to 100 curated homologs for BWI76_RS03535 FitnessBrowser__Koxy:BWI76_RS03535 (462 a.a.)

Found high-coverage hits (≥70%) to 47 curated proteins.

Removed hits that are identical to the query, leaving 46

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

tnaA / Q59342 tryptophanase subunit from Klebsiella aerogenes (see paper)
tnaA / BAA03249.1 tryptophanase from Klebsiella aerogenes (see paper)
    99% identity, 100% coverage of query (956 bits)

8v4aA / P28796 Proteus vulgaris tryptophan indole-lyase complexed with l-ethionine
    69% identity, 100% coverage of query (682 bits)

8v9pA Proteus vulgaris tryptophan indole-lyase complexed with (3s)- dioxindolyl-l-alanine
    69% identity, 100% coverage of query (682 bits)

8v6pB Tryptophanase
    69% identity, 100% coverage of query (682 bits)

8v4aB Proteus vulgaris tryptophan indole-lyase complexed with l-ethionine
    69% identity, 100% coverage of query (682 bits)

5w19A Tryptophan indole-lyase complex with oxindolyl-l-alanine
    69% identity, 100% coverage of query (682 bits)

P28796 tryptophanase (EC 4.1.99.1) from Proteus vulgaris (see 3 papers)
    69% identity, 100% coverage of query (681 bits)

8v6pA Tryptophanase
    69% identity, 100% coverage of query (681 bits)

8v2kA Proteus vulgaris tryptophan indole-lyase complexed with l-alanine
    68% identity, 100% coverage of query (669 bits)

8v2kB Proteus vulgaris tryptophan indole-lyase complexed with l-alanine
    68% identity, 100% coverage of query (663 bits)

A5EYI0 tryptophanase (EC 4.1.99.1) from Vibrio cholerae O1 (see paper)
    58% identity, 99% coverage of query (541 bits)

TnaA / b3708 tryptophanase (EC 4.1.99.1; EC 4.4.1.1; EC 4.4.1.28) from Escherichia coli K-12 substr. MG1655 (see 88 papers)
tnaA / P0A853 tryptophanase (EC 4.1.99.1; EC 4.4.1.1) from Escherichia coli (strain K12) (see 91 papers)
TNAA_ECOLI / P0A853 Tryptophanase; L-tryptophan indole-lyase; TNase; EC 4.1.99.1 from Escherichia coli (strain K12) (see 3 papers)
P0A853 tryptophanase (EC 4.1.99.1) from Escherichia coli (see 10 papers)
tnaA / RF|NP_418164 tryptophanase from Escherichia coli K12 (see 3 papers)
    58% identity, 100% coverage of query (536 bits)

2c44C / P0A853 Crystal structure of e. Coli tryptophanase (see paper)
    58% identity, 100% coverage of query (535 bits)

Q6LP64 tryptophanase (EC 4.1.99.1) from Photobacterium profundum (see paper)
    57% identity, 100% coverage of query (528 bits)

5d8gA A structural view on the dissociation of e. Coli tryptophanase
    58% identity, 100% coverage of query (528 bits)

tna1 / P31014 tryptophanase subunit from Symbiobacterium thermophilum (strain T / IAM 14863) (see paper)
    57% identity, 98% coverage of query (527 bits)

tna-1 / BAD39426.1 tryptophanase Tna1 from Symbiobacterium thermophilum IAM 14863 (see paper)
    57% identity, 98% coverage of query (527 bits)

P31015 tryptophanase (EC 4.1.99.1) from Symbiobacterium thermophilum (see paper)
tna-2 / BAD39424.1 tryptophanase Tna2 from Symbiobacterium thermophilum IAM 14863 (see paper)
    56% identity, 99% coverage of query (515 bits)

1c7gA / P31011 Tyrosine phenol-lyase from erwinia herbicola
    51% identity, 98% coverage of query (475 bits)

8sijA / A0A448M3A5 Crystal structure of f. Varium tryptophanase (see paper)
    52% identity, 100% coverage of query (474 bits)

4w1yB / P0A853 Crystal structure of escherichia coli tryptophanase in 'semi-holo' form (see paper)
    54% identity, 100% coverage of query (466 bits)

8sijB Crystal structure of f. Varium tryptophanase
    51% identity, 100% coverage of query (466 bits)

BAD41827.1 tyrosine phenol-lyase from Symbiobacterium thermophilum IAM 14863 (see paper)
    52% identity, 99% coverage of query (464 bits)

E9RK37 tryptophanase (EC 4.1.99.1) from Prevotella intermedia (see paper)
    51% identity, 98% coverage of query (464 bits)

Q8RHM6 tyrosine phenol-lyase (EC 4.1.99.2) from Fusobacterium nucleatum subsp. nucleatum (see 2 papers)
    52% identity, 98% coverage of query (463 bits)

BAA02365.1 beta-tyrosinase from Symbiobacterium thermophilum (see paper)
    52% identity, 99% coverage of query (461 bits)

P31013 tyrosine phenol-lyase (EC 4.1.99.2) from Citrobacter freundii (see 10 papers)
    50% identity, 98% coverage of query (459 bits)

6nv8B Perdeuterated tyrosine phenol-lyase from citrobacter freundii complexed with an aminoacrylate intermediate formed from s-ethyl-l- cysteine and 4-hydroxypyridine
    50% identity, 98% coverage of query (459 bits)

2yctA Tyrosine phenol-lyase from citrobacter freundii in complex with pyridine n-oxide and the quinonoid intermediate formed with l-alanine
    50% identity, 98% coverage of query (459 bits)

2vlhA Quinonoid intermediate of citrobacter freundii tyrosine phenol-lyase formed with methionine
    50% identity, 98% coverage of query (459 bits)

2vlfA Quinonoid intermediate of citrobacter freundii tyrosine phenol-lyase formed with alanine
    50% identity, 98% coverage of query (459 bits)

2ez2A Apo tyrosine phenol-lyase from citrobacter freundii at ph 8.0
    50% identity, 98% coverage of query (459 bits)

6mpdA Citrobacter freundii tyrosine phenol-lyase complexed with 4- hydroxypyridine and aminoacrylate from 3-f-l-tyrosine
    50% identity, 98% coverage of query (459 bits)

6mo3B Citrobacter freundii tyrosine phenol-lyase complexed with 4- hydroxypyridine and aminoacrylate from l-serine
    50% identity, 98% coverage of query (459 bits)

6mlsA Citrobacter freundii tyrosine phenol-lyase complexed with 4- hydroxypyridine and aminoacrylate from l-tyrosine
    50% identity, 98% coverage of query (459 bits)

6durB Citrobacter freundii tyrosine phenol-lyase complexed with l- phenylalanine
    50% identity, 98% coverage of query (459 bits)

2tplB Tyrosine phenol-lyase from citrobacter intermedius complex with 3-(4'- hydroxyphenyl)propionic acid, pyridoxal-5'-phosphate and cs+ ion
    50% identity, 98% coverage of query (459 bits)

6dytB Citrobacter freundii tyrosine phenol-lyase f448a mutant complexed with l-alanine
    50% identity, 98% coverage of query (459 bits)

6dytA Citrobacter freundii tyrosine phenol-lyase f448a mutant complexed with l-alanine
    50% identity, 98% coverage of query (459 bits)

7tdlA M379a mutant tyrosine phenol-lyase complexed with 3-bromo-dl- phenylalanine
    50% identity, 98% coverage of query (458 bits)

7tcsA M379a mutant tyrosine phenol-lyase complexed with l-methionine
    50% identity, 98% coverage of query (458 bits)

2ycnA Y71f mutant of tyrosine phenol-lyase from citrobacter freundii in complex with quinonoid intermediate formed with 3-fluoro-l-tyrosine
    50% identity, 98% coverage of query (458 bits)

6durA Citrobacter freundii tyrosine phenol-lyase complexed with l- phenylalanine
    50% identity, 98% coverage of query (451 bits)

8sbgA / A0A3E5GM45 Crystal structure of b. Theta tryptophanase in holo form (see paper)
    51% identity, 98% coverage of query (438 bits)

8sl7D / A0A845MXR5 Butyricicoccus sp. Bioml-a1 tryptophanase complex with (3s) alg-05 (see paper)
    32% identity, 99% coverage of query (256 bits)

Build an alignment

Build an alignment for BWI76_RS03535 and 45 homologs with ≥ 30% identity

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Additional hits (identity < 30%)

lnmJ / Q8GGP2 leinamycin polyketide synthase LnmJ from Streptomyces atroolivaceus (see 5 papers)
    25% identity, 78% coverage of query (75.1 bits)

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