Searching for up to 100 curated homologs for BWI76_RS03865 BWI76_RS03865 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase (488 a.a.)
Found high-coverage hits (≥70%) to 100 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
hpaE / Q46979 subunit of 5-carboxymethyl-2-hydroxymuconic semialdehyde dehydrogenase (EC 1.2.1.60) from Escherichia coli (see 2 papers)
97% identity, 100% coverage of query (984 bits)
HPCC_ECOLX / P42269 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase; CHMS dehydrogenase; EC 1.2.1.60 from Escherichia coli (see paper)
95% identity, 95% coverage of query (899 bits)
2d4eC / Q5SJP9 Crystal structure of the hpcc from thermus thermophilus hb8
48% identity, 99% coverage of query (457 bits)
praB / C4TP02 2-hydroxymuconate-6-semialdehyde dehydrogenase (EC 1.2.1.85) from Paenibacillus sp. JJ-1b (see paper)
praB / BAH79100.1 2-hydroxymuconate-6-semialdehyde dehydrogenase from Paenibacillus sp. JJ-1b (see paper)
46% identity, 97% coverage of query (438 bits)
A9YD19 retinal dehydrogenase (EC 1.2.1.36) from Danio rerio (see paper)
46% identity, 97% coverage of query (425 bits)
ALDH8A1 / Q9H2A2 aminomuconate-semialdehyde dehydrogenase (EC 1.2.1.32) from Homo sapiens (see 2 papers)
AL8A1_HUMAN / Q9H2A2 2-aminomuconic semialdehyde dehydrogenase; Aldehyde dehydrogenase 12; Aldehyde dehydrogenase family 8 member A1; EC 1.2.1.32 from Homo sapiens (Human) (see 2 papers)
Q9H2A2 aldehyde dehydrogenase (NAD+) (EC 1.2.1.3); aminomuconate-semialdehyde dehydrogenase (EC 1.2.1.32) from Homo sapiens (see 2 papers)
42% identity, 97% coverage of query (408 bits)
Q9FAB1 long-chain-aldehyde dehydrogenase (EC 1.2.1.48) from Geobacillus thermoleovorans (see paper)
44% identity, 98% coverage of query (397 bits)
AL2B4_ARATH / Q9SU63 Aldehyde dehydrogenase family 2 member B4, mitochondrial; ALDH2a; EC 1.2.1.3 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
43% identity, 98% coverage of query (387 bits)
Q9CZS1 aldehyde dehydrogenase (NAD+) (EC 1.2.1.3) from Mus musculus (see 2 papers)
42% identity, 97% coverage of query (384 bits)
AL8A1_MOUSE / Q8BH00 2-aminomuconic semialdehyde dehydrogenase; Aldehyde dehydrogenase family 8 member A1; Retinal dehydrogenase 4; EC 1.2.1.32 from Mus musculus (Mouse) (see paper)
Q8BH00 aldehyde dehydrogenase (NAD+) (EC 1.2.1.3) from Mus musculus (see paper)
41% identity, 97% coverage of query (383 bits)
7mjcA / P30837 Crystal structure analysis of aldh1b1
41% identity, 97% coverage of query (381 bits)
P30837 aldehyde dehydrogenase (NAD+) (EC 1.2.1.3) from Homo sapiens (see 2 papers)
41% identity, 97% coverage of query (381 bits)
7radA Crystal structure analysis of aldh1b1
41% identity, 97% coverage of query (381 bits)
7mjdA Crystal structure analysis of aldh1b1
41% identity, 97% coverage of query (381 bits)
nbaE / Q83V33 2-aminomuconate 6-semialdehyde dehydrogenase (EC 1.2.1.32) from Pseudomonas fluorescens (see paper)
Q83V33 aminomuconate-semialdehyde dehydrogenase (EC 1.2.1.32) from Pseudomonas fluorescens (see paper)
41% identity, 97% coverage of query (379 bits)
4npiA 1.94 angstroms x-ray crystal structure of NAD- and intermediate- bound alpha-aminomuconate-epsilon-semialdehyde dehydrogenase from pseudomonas fluorescens
41% identity, 97% coverage of query (379 bits)
4i2rA 2.15 angstroms x-ray crystal structure of NAD- and alternative substrate-bound 2-aminomuconate 6-semialdehyde dehydrogenase from pseudomonas fluorescens
41% identity, 97% coverage of query (379 bits)
4i25A 2.00 angstroms x-ray crystal structure of NAD- and substrate-bound 2- aminomuconate 6-semialdehyde dehydrogenase from pseudomonas fluorescens
41% identity, 97% coverage of query (379 bits)
5kj5B / Q83V33 Crystal structure of 2-aminomuconate 6-semialdehyde dehydrogenase n169d in complex with NAD+ (see paper)
40% identity, 98% coverage of query (377 bits)
5kllA Crystal structure of 2-hydroxymuconate-6-semialdehyde derived tautomeric intermediate in 2-aminomuconate 6-semialdehyde dehydrogenase n169d
40% identity, 98% coverage of query (377 bits)
4ou2A A 2.15 angstroms x-ray crystal structure of e268a 2-aminomuconate 6- semialdehyde dehydrogenase catalytic intermediate from pseudomonas fluorescens
40% identity, 97% coverage of query (377 bits)
4o6rA / B4EJX1 Crystal structure of a putative aldehyde dehydrogenase from burkholderia cenocepacia
41% identity, 98% coverage of query (376 bits)
BALDH_ANTMA / C7A2A0 Benzaldehyde dehydrogenase, mitochondrial; 2-phenylacetaldehyde dehydrogenase; Acetaldehyde dehydrogenase; EC 1.2.1.28; EC 1.2.1.39; EC 1.2.1.3 from Antirrhinum majus (Garden snapdragon) (see paper)
41% identity, 98% coverage of query (375 bits)
4fr8C / P05091 Crystal structure of human aldehyde dehydrogenase-2 in complex with nitroglycerin (see paper)
42% identity, 94% coverage of query (374 bits)
P20000 Aldehyde dehydrogenase, mitochondrial; ALDH class 2; ALDH-E2; ALDHI; EC 1.2.1.3 from Bos taurus (Bovine)
42% identity, 97% coverage of query (374 bits)
4fr8A Crystal structure of human aldehyde dehydrogenase-2 in complex with nitroglycerin
42% identity, 94% coverage of query (374 bits)
5l13A Structure of aldh2 in complex with 2p3
42% identity, 94% coverage of query (374 bits)
4kwgA Crystal structure analysis of aldh2+aldib13
42% identity, 94% coverage of query (374 bits)
4kwfA Crystal structure analysis of aldh2+aldib33
42% identity, 94% coverage of query (374 bits)
3sz9A Crystal structure of human aldh2 modified with the beta-elimination product of aldi-3; 1-(4-ethylbenzene)prop-2-en-1-one
42% identity, 94% coverage of query (374 bits)
3injA Human mitochondrial aldehyde dehydrogenase complexed with agonist alda-1
42% identity, 94% coverage of query (374 bits)
2vleA The structure of daidzin, a naturally occurring anti alcohol- addiction agent, in complex with human mitochondrial aldehyde dehydrogenase
42% identity, 94% coverage of query (374 bits)
1o01B Human mitochondrial aldehyde dehydrogenase complexed with crotonaldehyde, NAD(h) and mg2+
42% identity, 94% coverage of query (374 bits)
1cw3A Human mitochondrial aldehyde dehydrogenase complexed with NAD+ and mn2+
42% identity, 94% coverage of query (374 bits)
P11884 aldehyde dehydrogenase (NAD+) (EC 1.2.1.3); aldehyde dehydrogenase [NAD(P)+] (EC 1.2.1.5) from Rattus norvegicus (see 4 papers)
41% identity, 97% coverage of query (373 bits)
ALDH2 / P05091 mitochondrial aldehyde dehydrogenase subunit (EC 1.2.1.3; EC 1.2.1.39) from Homo sapiens (see 14 papers)
ALDH2_HUMAN / P05091 Aldehyde dehydrogenase, mitochondrial; ALDH class 2; ALDH-E2; ALDHI; EC 1.2.1.3 from Homo sapiens (Human) (see 2 papers)
P05091 aldehyde dehydrogenase (NAD+) (EC 1.2.1.3) from Homo sapiens (see 13 papers)
42% identity, 97% coverage of query (373 bits)
P47738 aldehyde dehydrogenase (NAD+) (EC 1.2.1.3) from Mus musculus (see 4 papers)
42% identity, 94% coverage of query (372 bits)
4cazA / Q9HTJ1 Crystal structure of betaine aldehyde dehydrogenase from pseudomonas aeruginosa in complex with nadh
41% identity, 97% coverage of query (372 bits)
AL2B7_ARATH / Q8S528 Aldehyde dehydrogenase family 2 member B7, mitochondrial; ALDH2b; EC 1.2.1.3 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
41% identity, 96% coverage of query (372 bits)
2woxA Betaine aldehyde dehydrogenase from pseudomonas aeruginosa with NAD(p) h-catalytic thiol adduct.
41% identity, 97% coverage of query (372 bits)
2wmeA Crystallographic structure of betaine aldehyde dehydrogenase from pseudomonas aeruginosa
41% identity, 97% coverage of query (372 bits)
BETB_PSEAE / Q9HTJ1 NAD/NADP-dependent betaine aldehyde dehydrogenase; BADH; EC 1.2.1.8 from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see 3 papers)
Q9HTJ1 betaine-aldehyde dehydrogenase (EC 1.2.1.8) from Pseudomonas aeruginosa (see 5 papers)
41% identity, 97% coverage of query (371 bits)
Q1XGK8 2-hydroxymuconate-6-semialdehyde dehydrogenase (EC 1.2.1.85) from Pseudomonas putida (see paper)
nahI / BAE92168.1 2-hydroxymuconic semialdehyde dehydrogenase NahI from Pseudomonas putida (see 2 papers)
41% identity, 98% coverage of query (370 bits)
ALDH4_BACSU / O34660 Putative aldehyde dehydrogenase DhaS; EC 1.2.1.3 from Bacillus subtilis (strain 168) (see paper)
41% identity, 97% coverage of query (370 bits)
1nzwA Cys302ser mutant of human mitochondrial aldehyde dehydrogenase complexed with nadh and mg2+
42% identity, 94% coverage of query (370 bits)
ALDH1A3 / P47895 retinal dehydrogenase 3 (EC 1.2.1.36) from Homo sapiens (see 3 papers)
AL1A3_HUMAN / P47895 Retinaldehyde dehydrogenase 3; RALDH-3; RalDH3; Aldehyde dehydrogenase 6; Aldehyde dehydrogenase family 1 member A3; ALDH1A3; EC 1.2.1.36 from Homo sapiens (Human) (see 9 papers)
P47895 retinal dehydrogenase (EC 1.2.1.36); aldehyde dehydrogenase [NAD(P)+] (EC 1.2.1.5) from Homo sapiens (see 6 papers)
40% identity, 98% coverage of query (369 bits)
7qk9A Crystal structure of the aldh1a3-atp complex
40% identity, 97% coverage of query (367 bits)
2onmA Human mitochondrial aldehyde dehydrogenase asian variant, aldh2 2, Complexed with NAD+
43% identity, 92% coverage of query (367 bits)
AL1A2_MOUSE / Q62148 Retinal dehydrogenase 2; RALDH 2; RalDH2; Aldehyde dehydrogenase family 1 member A2; ALDH1A2; Retinaldehyde-specific dehydrogenase type 2; RALDH(II); EC 1.2.1.36 from Mus musculus (Mouse) (see 3 papers)
Q62148 retinal dehydrogenase (EC 1.2.1.36) from Mus musculus (see 6 papers)
40% identity, 97% coverage of query (365 bits)
XYLG / AAC44160.1 2-hydroxy-5-methyl-6-oxohexa-2,4-dienoate dehydrogenase from Cycloclasticus oligotrophus (see paper)
39% identity, 98% coverage of query (365 bits)
pnpD / C6FI42 4-hydroxymuconic-semialdehyde dehydrogenase (EC 1.2.1.61) from Pseudomonas putida (see paper)
40% identity, 98% coverage of query (365 bits)
AL1A2_RAT / Q63639 Retinal dehydrogenase 2; RALDH 2; RalDH2; Aldehyde dehydrogenase family 1 member A2; ALDH1A2; Retinaldehyde-specific dehydrogenase type 2; RALDH(II); EC 1.2.1.36 from Rattus norvegicus (Rat) (see paper)
Q63639 retinal dehydrogenase (EC 1.2.1.36) from Rattus norvegicus (see 4 papers)
40% identity, 97% coverage of query (365 bits)
7a6qA / P47895 Crystal structure of human aldehyde dehydrogenase 1a3 in complex with selective nr6 inhibitor compound (see paper)
40% identity, 97% coverage of query (365 bits)
ALDH1A2 / O94788 retinal dehydrogenase 2 (EC 1.2.1.36) from Homo sapiens (see 4 papers)
AL1A2_HUMAN / O94788 Retinal dehydrogenase 2; RALDH 2; RalDH2; Aldehyde dehydrogenase family 1 member A2; ALDH1A2; Retinaldehyde-specific dehydrogenase type 2; RALDH(II); EC 1.2.1.36 from Homo sapiens (Human) (see 3 papers)
O94788 retinal dehydrogenase (EC 1.2.1.36) from Homo sapiens (see 6 papers)
40% identity, 97% coverage of query (365 bits)
7a6qB Crystal structure of human aldehyde dehydrogenase 1a3 in complex with selective nr6 inhibitor compound
40% identity, 97% coverage of query (365 bits)
5fhzA Human aldehyde dehydrogenase 1a3 complexed with NAD(+) and retinoic acid
40% identity, 97% coverage of query (365 bits)
6aljA / O94788 Aldh1a2 liganded with NAD and compound win18,446 (see paper)
40% identity, 97% coverage of query (364 bits)
6b5hA Aldh1a2 liganded with NAD and 1-(4-cyanophenyl)-n-(3-fluorophenyl)-3- [4-(methylsulfonyl)phenyl]-1h-pyrazole-4-carboxamide (compound cm121)
40% identity, 97% coverage of query (364 bits)
6b5gA Aldh1a2 liganded with NAD and (3-ethoxythiophen-2-yl){4-[4-nitro-3- (pyrrolidin-1-yl)phenyl]piperazin-1-yl}methanone (compound 6-118)
40% identity, 97% coverage of query (364 bits)
cymC / O33455 cumic aldehyde dehydrogenase (EC 1.2.1.29) from Pseudomonas putida (see paper)
cymc / AAB62298.1 p-cumic aldehyde dehydrogenase from Pseudomonas putida (see 3 papers)
41% identity, 94% coverage of query (363 bits)
7rluA / P28037 Structure of aldh1l1 (10-formyltetrahydrofolate dehydrogenase) in complex with NADP (see paper)
39% identity, 94% coverage of query (363 bits)
F8TW85 4-hydroxymuconic-semialdehyde dehydrogenase (EC 1.2.1.61) from Sphingomonas sp. (see paper)
41% identity, 97% coverage of query (363 bits)
6tryA Crystal structure of human aldehyde dehydrogenase 1a3 in complex with mf13 inhibitor compound
39% identity, 97% coverage of query (363 bits)
6te5B Crystal structure of human aldehyde dehydrogenase 1a3 in complex with lq43 inhibitor compound
39% identity, 97% coverage of query (363 bits)
4go2A Crystal structure of thE C-terminal domain of 10'formyltetrahydrofolate dehydrogenase in complex with thio-NADP
39% identity, 94% coverage of query (363 bits)
2o2rA Crystal structure of thE C-terminal domain of rat 10'formyltetrahydrofolate dehydrogenase in complex with NADPH
39% identity, 94% coverage of query (363 bits)
6tgwA Crystal structure of human aldehyde dehydrogenase 1a3 in complex with a selective inhibitor
39% identity, 97% coverage of query (363 bits)
4pxlA / Q8S532 Structure of zm aldh2-3 (rf2c) in complex with NAD (see paper)
42% identity, 98% coverage of query (362 bits)
AL1L1_MOUSE / Q8R0Y6 Cytosolic 10-formyltetrahydrofolate dehydrogenase; 10-FTHFDH; FDH; Aldehyde dehydrogenase family 1 member L1; EC 1.5.1.6 from Mus musculus (Mouse) (see paper)
39% identity, 95% coverage of query (362 bits)
AL1L1_RAT / P28037 Cytosolic 10-formyltetrahydrofolate dehydrogenase; 10-FTHFDH; FDH; Aldehyde dehydrogenase family 1 member L1; FBP-CI; EC 1.5.1.6 from Rattus norvegicus (Rat) (see 7 papers)
P28037 formyltetrahydrofolate dehydrogenase (EC 1.5.1.6) from Rattus norvegicus (see 3 papers)
39% identity, 95% coverage of query (362 bits)
5gtkA NAD+ complex structure of aldehyde dehydrogenase from bacillus cereus
39% identity, 98% coverage of query (361 bits)
AL2C4_ARATH / Q56YU0 Aldehyde dehydrogenase family 2 member C4; ALDH1a; Protein REDUCED EPIDERMAL FLUORESCENCE 1; EC 1.2.1.3 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
41% identity, 98% coverage of query (361 bits)
pdcG / D2STN3 4-hydroxymuconic-semialdehyde dehydrogenase (EC 1.2.1.61) from Pseudomonas sp. 1-7 (see paper)
42% identity, 94% coverage of query (361 bits)
5gtlA NADPH complex structure of aldehyde dehydrogenase from bacillus cereus
39% identity, 98% coverage of query (361 bits)
Q9FRX7 aldehyde dehydrogenase [NAD(P)+] (EC 1.2.1.5) from Oryza sativa (see paper)
41% identity, 96% coverage of query (360 bits)
Q9DD46 retinal dehydrogenase (EC 1.2.1.36) from Gallus gallus (see paper)
39% identity, 94% coverage of query (359 bits)
pnpE / C1I208 maleylacetate reductase (EC 1.3.1.32) from Pseudomonas sp. (strain WBC-3) (see paper)
C1I208 4-hydroxymuconic-semialdehyde dehydrogenase (EC 1.2.1.61) from Pseudomonas sp. WBC-3 (see paper)
42% identity, 94% coverage of query (358 bits)
4go4A / C1I208 Crystal structure of pnpe in complex with nicotinamide adenine dinucleotide
42% identity, 94% coverage of query (358 bits)
Q155V4 betaine-aldehyde dehydrogenase (EC 1.2.1.8) from Suaeda salsa (see paper)
Q8W5A1 betaine-aldehyde dehydrogenase (EC 1.2.1.8) from Suaeda liaotungensis (see 2 papers)
39% identity, 95% coverage of query (358 bits)
Q8K4D8 retinal dehydrogenase (EC 1.2.1.36) from Rattus norvegicus (see paper)
40% identity, 95% coverage of query (358 bits)
AL1A3_MOUSE / Q9JHW9 Retinaldehyde dehydrogenase 3; RALDH-3; RalDH3; Aldehyde dehydrogenase 6; Aldehyde dehydrogenase family 1 member A3; Aldh1a3; EC 1.2.1.36 from Mus musculus (Mouse) (see 7 papers)
Q9JHW9 retinal dehydrogenase (EC 1.2.1.36); aldehyde dehydrogenase [NAD(P)+] (EC 1.2.1.5) from Mus musculus (see 4 papers)
39% identity, 97% coverage of query (358 bits)
5abmA / P51977 Sheep aldehyde dehydrogenase 1a1 (see paper)
40% identity, 97% coverage of query (357 bits)
5ac0A Ovis aries aldehyde dehydrogenase 1a1 in complex with a duocarmycin analog
40% identity, 97% coverage of query (357 bits)
1bxsA Sheep liver class 1 aldehyde dehydrogenase with NAD bound
40% identity, 97% coverage of query (357 bits)
AL1L2_MOUSE / Q8K009 Mitochondrial 10-formyltetrahydrofolate dehydrogenase; Mitochondrial 10-FTHFDH; mtFDH; Aldehyde dehydrogenase family 1 member L2; EC 1.5.1.6 from Mus musculus (Mouse) (see paper)
40% identity, 96% coverage of query (356 bits)
AL1A1_SHEEP / P51977 Aldehyde dehydrogenase 1A1; 3-deoxyglucosone dehydrogenase; ALDH-E1; ALHDII; Aldehyde dehydrogenase family 1 member A1; Aldehyde dehydrogenase, cytosolic; Retinal dehydrogenase 1; RALDH 1; RalDH1; EC 1.2.1.19; EC 1.2.1.28; EC 1.2.1.3; EC 1.2.1.36 from Ovis aries (Sheep) (see 2 papers)
40% identity, 97% coverage of query (356 bits)
AL1A1_BOVIN / P48644 Aldehyde dehydrogenase 1A1; 3-deoxyglucosone dehydrogenase; ALDH-E1; ALHDII; Aldehyde dehydrogenase family 1 member A1; Aldehyde dehydrogenase, cytosolic; Retinal dehydrogenase 1; RALDH 1; RalDH1; EC 1.2.1.19; EC 1.2.1.28; EC 1.2.1.3; EC 1.2.1.36 from Bos taurus (Bovine) (see paper)
40% identity, 97% coverage of query (356 bits)
ipuH / Q936S5 aldehyde dehydrogenase from Pseudomonas sp. KIE171 (see paper)
41% identity, 97% coverage of query (355 bits)
P27463 retinal dehydrogenase (EC 1.2.1.36) from Gallus gallus (see 2 papers)
40% identity, 97% coverage of query (355 bits)
aldA / RF|XP_658158.1 aldehyde dehydrogenase ALDH; EC 1.2.1.3 from Emericella nidulans (see 5 papers)
40% identity, 97% coverage of query (355 bits)
8skfA / A0A447LC14 Crystal structure of betaine aldehyde dehydrogenase (betb) from klebsiella aerogenes (lattice translocation disorder)
39% identity, 98% coverage of query (355 bits)
8vr1A Crystal structure of betaine aldehyde dehydrogenase (betb) from klebsiella aerogenes (ctp bound)
39% identity, 98% coverage of query (355 bits)
8vr0A Crystal structure of betaine aldehyde dehydrogenase (betb) from klebsiella aerogenes (gmp bound)
39% identity, 98% coverage of query (355 bits)
8vqzA Crystal structure of betaine aldehyde dehydrogenase (betb) from klebsiella aerogenes (cmp bound)
39% identity, 98% coverage of query (355 bits)
8vqwC Crystal structure of betaine aldehyde dehydrogenase (betb) from klebsiella aerogenes (coa bound)
39% identity, 98% coverage of query (355 bits)
8vj3A Crystal structure of betaine aldehyde dehydrogenase (betb) from klebsiella aerogenes (fad bound)
39% identity, 98% coverage of query (355 bits)
8uzoA Crystal structure of betaine aldehyde dehydrogenase (betb) from klebsiella aerogenes (adp bound)
39% identity, 98% coverage of query (355 bits)
8uznA Crystal structure of betaine aldehyde dehydrogenase (betb) from klebsiella aerogenes (amp bound)
39% identity, 98% coverage of query (355 bits)
8uzmA Crystal structure of betaine aldehyde dehydrogenase (betb) from klebsiella aerogenes (NADPH bound)
39% identity, 98% coverage of query (355 bits)
8uzkA Crystal structure of betaine aldehyde dehydrogenase (betb) from klebsiella aerogenes (NADP+ bound)
39% identity, 98% coverage of query (355 bits)
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