Sites on a Tree

 

Searching for up to 100 curated homologs for BWI76_RS04585 FitnessBrowser__Koxy:BWI76_RS04585 (500 a.a.)

Found high-coverage hits (≥70%) to 40 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

AraA / b0062 L-arabinose isomerase (EC 5.3.1.4) from Escherichia coli K-12 substr. MG1655 (see 9 papers)
araA / P08202 L-arabinose isomerase (EC 5.3.1.4) from Escherichia coli (strain K12) (see 8 papers)
ARAA_ECOLI / P08202 L-arabinose isomerase; EC 5.3.1.4 from Escherichia coli (strain K12) (see 3 papers)
P08202 L-arabinose isomerase (EC 5.3.1.4) from Escherichia coli (see 2 papers)
    90% identity, 100% coverage of query (964 bits)

Q8FL89 L-arabinose isomerase (EC 5.3.1.4) from Escherichia coli (see paper)
    90% identity, 100% coverage of query (964 bits)

P58538 L-arabinose isomerase (EC 5.3.1.4) from Escherichia coli (see paper)
    90% identity, 100% coverage of query (963 bits)

4f2dA / P08202 Crystal structure of escherichia coli l-arabinose isomerase (ecai) complexed with ribitol
    90% identity, 99% coverage of query (963 bits)

P58539 L-arabinose isomerase (EC 5.3.1.4) from Salmonella enterica subsp. enterica serovar Typhi (see paper)
    90% identity, 100% coverage of query (958 bits)

P06189 L-arabinose isomerase (EC 5.3.1.4) from Salmonella enterica subsp. enterica serovar Typhimurium (see paper)
    90% identity, 100% coverage of query (957 bits)

Q7UDT4 L-arabinose isomerase (EC 5.3.1.4) from Shigella flexneri (see paper)
    89% identity, 100% coverage of query (953 bits)

P58540 L-arabinose isomerase (EC 5.3.1.4) from Yersinia pestis (see paper)
    74% identity, 100% coverage of query (801 bits)

7chlA / K0IGW6,P08202,Q5KYP7 Crystal structure of hybrid arabinose isomerase ai-10
    64% identity, 98% coverage of query (660 bits)

Q6W9D4 L-arabinose isomerase (EC 5.3.1.4) from Geobacillus thermodenitrificans (see 3 papers)
    61% identity, 99% coverage of query (646 bits)

Q2VMT2 L-arabinose isomerase (EC 5.3.1.4) from Alicyclobacillus acidocaldarius (see paper)
    61% identity, 99% coverage of query (641 bits)

ARAA_GEOSE / Q9S467 L-arabinose isomerase; EC 5.3.1.4 from Geobacillus stearothermophilus (Bacillus stearothermophilus) (see 2 papers)
Q9S467 L-arabinose isomerase (EC 5.3.1.4) from Geobacillus stearothermophilus (see 4 papers)
    60% identity, 99% coverage of query (641 bits)

F6KRI7 L-arabinose isomerase (EC 5.3.1.4) from Anoxybacillus flavithermus (see paper)
    60% identity, 99% coverage of query (640 bits)

Q5KYP7 L-arabinose isomerase (EC 5.3.1.4) from Geobacillus kaustophilus (see paper)
4r1qE / Q5KYP7 Crystal structure of thermophilic geobacillus kaustophilus l-arabinose isomerase in complex with l-arabitol
    60% identity, 99% coverage of query (640 bits)

7cyyC / K0IGW6,Q2VMT2,Q5KYP7 Crystal structure of arabinose isomerase from hybrid ai8 with adonitol
    59% identity, 99% coverage of query (625 bits)

Echvi_1879 L-arabinose isomerase (EC 5.3.1.4) from Echinicola vietnamensis KMM 6221, DSM 17526
    58% identity, 98% coverage of query (614 bits)

Q9KBQ2 L-arabinose isomerase (EC 5.3.1.4) from Alkalihalobacillus halodurans (see paper)
    58% identity, 98% coverage of query (608 bits)

J9E728 L-arabinose isomerase (EC 5.3.1.4) from Alicyclobacillus hesperidum (see paper)
    56% identity, 99% coverage of query (600 bits)

CA265_RS08615 L-arabinose isomerase (EC 5.3.1.4) from Pedobacter sp. GW460-11-11-14-LB5
    54% identity, 99% coverage of query (586 bits)

Q9WYB3 L-arabinose isomerase (EC 5.3.1.4) from Thermotoga maritima (see paper)
    55% identity, 99% coverage of query (584 bits)

7ch3B / Q9WYB3 Crystal structure of arabinose isomerase from hyper thermophilic bacterium thermotoga maritima (tmai) triple mutant (k264a, e265a, k266a)
    55% identity, 99% coverage of query (582 bits)

Q6VAK6 L-arabinose isomerase (EC 5.3.1.4) from Parageobacillus thermoglucosidasius (see paper)
    53% identity, 98% coverage of query (565 bits)

ARAA_BACSU / P94523 L-arabinose isomerase; EC 5.3.1.4 from Bacillus subtilis (strain 168) (see paper)
P94523 L-arabinose isomerase (EC 5.3.1.4) from Bacillus subtilis (see paper)
    52% identity, 98% coverage of query (560 bits)

7ch3A / Q9WYB3 Crystal structure of arabinose isomerase from hyper thermophilic bacterium thermotoga maritima (tmai) triple mutant (k264a, e265a, k266a)
    53% identity, 99% coverage of query (559 bits)

Shewana3_2066 L-arabinose isomerase (EC 5.3.1.4) from Shewanella sp. ANA-3
    51% identity, 100% coverage of query (548 bits)

Q97JE0 L-arabinose isomerase (EC 5.3.1.4) from Clostridium acetobutylicum (see paper)
    51% identity, 95% coverage of query (528 bits)

A0LT86 L-arabinose isomerase (EC 5.3.1.4) from Acidothermus cellulolyticus (see paper)
    50% identity, 97% coverage of query (525 bits)

C0C0X3 L-arabinose isomerase (EC 5.3.1.4) from [Clostridium] hylemonae (see paper)
    50% identity, 99% coverage of query (520 bits)

H6UGW9 L-arabinose isomerase (EC 5.3.1.4) from Arthrobacter sp. (see paper)
    50% identity, 99% coverage of query (519 bits)

Q65J10 L-arabinose isomerase (EC 5.3.1.4) from Bacillus licheniformis (see 2 papers)
    52% identity, 94% coverage of query (513 bits)

A0A1L2F0V9 L-arabinose isomerase (EC 5.3.1.4) from Enterococcus faecium (see paper)
    51% identity, 94% coverage of query (510 bits)

Q8EMP4 L-arabinose isomerase (EC 5.3.1.4) from Oceanobacillus iheyensis (see paper)
    50% identity, 95% coverage of query (505 bits)

Q97JE4 L-arabinose isomerase (EC 5.3.1.4) from Clostridium acetobutylicum (see paper)
    50% identity, 95% coverage of query (496 bits)

A0A191W0D9 L-arabinose isomerase (EC 5.3.1.4) from Weizmannia coagulans (see paper)
    48% identity, 94% coverage of query (482 bits)

Q8AAW1 L-arabinose isomerase (EC 5.3.1.4) from Bacteroides thetaiotaomicron (see paper)
    46% identity, 99% coverage of query (476 bits)

I3ZR32 L-arabinose isomerase (EC 5.3.1.4) from Bifidobacterium longum (see paper)
Q8G7J3 L-arabinose isomerase (EC 5.3.1.4) from Bifidobacterium longum (see paper)
    46% identity, 99% coverage of query (468 bits)

G1JRK8 L-arabinose isomerase (EC 5.3.1.4) from Pediococcus pentosaceus (see paper)
    47% identity, 94% coverage of query (456 bits)

Q88S84 L-arabinose isomerase (EC 5.3.1.4) from Lactiplantibacillus plantarum (see paper)
    47% identity, 93% coverage of query (450 bits)

D9ILD9 L-arabinose isomerase (EC 5.3.1.4) from Limosilactobacillus fermentum (see 2 papers)
    45% identity, 95% coverage of query (423 bits)

Build an alignment

Build an alignment for BWI76_RS04585 and 39 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

Q70G56 L-arabinose isomerase (EC 5.3.1.4) from Thermoanaerobacter mathranii (see paper)
    29% identity, 93% coverage of query (168 bits)

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory