Searching for up to 100 curated homologs for BWI76_RS05360 FitnessBrowser__Koxy:BWI76_RS05360 (217 a.a.)
Found high-coverage hits (≥70%) to 26 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
MetI / b0198 L-methionine/D-methionine ABC transporter membrane subunit (EC 7.4.2.11) from Escherichia coli K-12 substr. MG1655 (see 7 papers)
MetI / P31547 L-methionine/D-methionine ABC transporter membrane subunit (EC 7.4.2.11) from Escherichia coli (strain K12) (see 2 papers)
METI_ECOLI / P31547 D-methionine transport system permease protein MetI from Escherichia coli (strain K12) (see 3 papers)
P31547 ABC-type methionine transporter (subunit 1/2) (EC 7.4.2.11) from Escherichia coli (see 3 papers)
TC 3.A.1.24.1 / P31547 MetI, D-methionine transport system permease protein, component of The L- and D-methionine porter (also transports formyl-L-methionine and other methionine derivatives) (Zhang et al., 2003). The 3.7A structure of MetNI has been solved. An allosteric regulatory mechanism operates at the level of transport activity, so increased intracellular levels of the transported ligand stabilize an inward-facing, ATPase-inactive state of MetNI to inhibit further ligand translocation into the cell from Escherichia coli (see 4 papers)
97% identity, 100% coverage of query (360 bits)
METP_BACSU / O32168 Methionine import system permease protein MetP from Bacillus subtilis (strain 168) (see paper)
TC 3.A.1.24.2 / O32168 MetP (M) (aka YusB), component of The L- and D-methionine porter (also transports methionine sulfoxide from Bacillus subtilis subsp. subtilis str. 168 (see 2 papers)
47% identity, 82% coverage of query (156 bits)
TC 3.A.1.24.5 / Q9HT69 D-methionine ABC transporter membrane protein, component of L-Histidine uptake porter, MetIQN from Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
52% identity, 82% coverage of query (144 bits)
TC 3.A.1.24.3 / Q8K8K7 AtmE, component of The methionine porter, AtmBDE from Streptococcus pyogenes serotype M3 (see 2 papers)
42% identity, 95% coverage of query (114 bits)
Build an alignment for BWI76_RS05360 and 4 homologs with ≥ 30% identity
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TC 3.A.1.12.7 / Q92N36 ChoW, component of High affinity (3 μM) choline-specific uptake system from Rhizobium meliloti (Sinorhizobium meliloti) (see 2 papers)
28% identity, 75% coverage of query (63.2 bits)
TC 3.A.1.12.13 / Q7CXG1 ABC transporter, membrane spanning protein (Proline/glycine betaine), component of High affinity (2mμM) choline uptake porter. The choline binding receptor exhibits a venus fly trap mechanism of substrate binding. (ChoX binds acetyl choline and betaine with low affinity (80μM and 470μM, respectively) (Aktas et al., 2011) (most similar to 3.A.1.12.7) from Agrobacterium tumefaciens (strain C58 / ATCC 33970) (see 2 papers)
29% identity, 73% coverage of query (59.3 bits)
A0A077T980 ABC-type quaternary amine transporter (subunit 3/3) (EC 7.6.2.9) from Vibrio anguillarum serotype O1 (see paper)
28% identity, 76% coverage of query (59.3 bits)
TC 3.A.1.12.9 / Q8U4S4 OtaB, component of The salt-induced glycine betaine OtaABC transporter from Methanosarcina mazei (see paper)
28% identity, 94% coverage of query (58.5 bits)
AO353_16280 ABC transporter for L-aspartate, L-asparagine, L-glutamate, and L-glutamine, permease component 1 from Pseudomonas fluorescens FW300-N2E3
28% identity, 96% coverage of query (56.6 bits)
OUSW_DICD3 / E0SCY2 Glycine betaine/choline transport system permease protein OusW from Dickeya dadantii (strain 3937) (Erwinia chrysanthemi (strain 3937)) (see paper)
27% identity, 76% coverage of query (56.6 bits)
U5LHK3 ABC-type quaternary amine transporter (subunit 2/3) (EC 7.6.2.9) from Bacillus infantis (see paper)
30% identity, 78% coverage of query (56.6 bits)
OPUBB_BACSU / Q45461 Choline transport system permease protein OpuBB from Bacillus subtilis (strain 168) (see 2 papers)
TC 3.A.1.12.3 / Q45461 OPBB aka OpuBB aka PROW, component of Choline porter from Bacillus subtilis (see 3 papers)
27% identity, 82% coverage of query (56.2 bits)
PfGW456L13_4772 ABC transporter for L-Asparagine and possibly other L-amino acids, permease component 2 from Pseudomonas fluorescens GW456-L13
27% identity, 95% coverage of query (55.8 bits)
PHNE_MYCS2 / A0QQ68 Phosphate-import permease protein PhnE from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis) (see paper)
28% identity, 76% coverage of query (55.1 bits)
GLUD_CORGL / P48245 Glutamate transport system permease protein GluD; Glutamate uptake system protein GluD from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) (see paper)
TC 3.A.1.3.9 / P48245 GluD aka CGL1953, component of Glutamate porter from Corynebacterium glutamicum (Brevibacterium flavum) (see 2 papers)
25% identity, 93% coverage of query (53.9 bits)
OSMY_SALTY / Q8ZPK1 Osmoprotectant import permease protein OsmY from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
TC 3.A.1.12.14 / Q8ZPK1 ABC-type transport system protein, component of OsmU (OsmVWXY) transporter for glycine betaine and choline-O-sulfate uptake. Induced by osmotic stress (0.3M NaCl) (Frossard et al., 2012). Also called OpuCA/CB1/CB2/CC from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
30% identity, 74% coverage of query (53.5 bits)
TC 3.A.1.3.17 / Q8YSA2 Basic amino acid uptake transporter, BgtAB (see paper)
29% identity, 71% coverage of query (53.5 bits)
ARTQ_BACSU / P54536 Arginine transport system permease protein ArtQ from Bacillus subtilis (strain 168) (see paper)
27% identity, 84% coverage of query (52.8 bits)
OPUCB_LISM4 / G2JZ43 Carnitine transport permease protein OpuCB from Listeria monocytogenes serotype 1/2a (strain 10403S) (see 4 papers)
OPUCB_LISMN / Q9KHT8 Carnitine transport permease protein OpuCB from Listeria monocytogenes (see paper)
25% identity, 74% coverage of query (51.2 bits)
YehY / b2130 glycine betaine ABC transporter membrane subunit YehY from Escherichia coli K-12 substr. MG1655 (see 4 papers)
yehY / P33361 glycine betaine ABC transporter membrane subunit YehY from Escherichia coli (strain K12) (see 2 papers)
YEHY_ECOLI / P33361 Glycine betaine uptake system permease protein YehY from Escherichia coli (strain K12) (see 3 papers)
27% identity, 76% coverage of query (50.8 bits)
AO353_07785 ABC transporter for Carnitine, permease component from Pseudomonas fluorescens FW300-N2E3
26% identity, 75% coverage of query (50.4 bits)
EGTUB_LISMO / Q8Y775 Probable ergothioneine transporter EgtUBC from Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e) (see 2 papers)
30% identity, 71% coverage of query (48.5 bits)
TC 3.A.1.12.8 / Q93A34 BilEB aka OpuBB protein, component of A proline/glycine betaine uptake system. Also reported to be a bile exclusion system that exports oxgall and other bile compounds, BilEA/EB or OpuBA/BB (required for normal virulence) from Listeria monocytogenes (see paper)
30% identity, 71% coverage of query (48.5 bits)
GBUB_LISM4 / Q9RR45 Glycine betaine/carnitine transport permease protein GbuB from Listeria monocytogenes serotype 1/2a (strain 10403S) (see 4 papers)
25% identity, 74% coverage of query (48.5 bits)
OPUCD_LISM4 / G2JZ41 Carnitine transport permease protein OpuCD from Listeria monocytogenes serotype 1/2a (strain 10403S) (see 4 papers)
OPUCD_LISMN / Q9KHT6 Carnitine transport permease protein OpuCD from Listeria monocytogenes (see paper)
26% identity, 75% coverage of query (48.5 bits)
TC 3.A.1.12.6 / Q9KKE2 HutW aka HISW, component of Uptake system for hisitidine, proline, proline-betaine and glycine-betaine from Rhizobium meliloti (Sinorhizobium meliloti) (see paper)
25% identity, 76% coverage of query (48.1 bits)
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Lawrence Berkeley National Laboratory