Searching for up to 100 curated homologs for BWI76_RS05690 FitnessBrowser__Koxy:BWI76_RS05690 (282 a.a.)

Found high-coverage hits (≥70%) to 30 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

dntG / Q8VUC7 2,4-dihydroxy-5-methyl-6-oxohexa-2,4-dienoate isomerase from Burkholderia cepacia (see 2 papers)
    41% identity, 98% coverage of query (204 bits)

SM_b21112 L-2,4-diketo-3-deoxyrhamnonate hydrolase; 2,4-dioxopentanoate hydrolase from Sinorhizobium meliloti 1021
    37% identity, 99% coverage of query (166 bits)

8skyB / A0A0D6X359 Crystal structure of yisk from bacillus subtilis in complex with oxalate (see paper)
    40% identity, 76% coverage of query (155 bits)

YISK_BACSU / O06724 Uncharacterized protein YisK from Bacillus subtilis (strain 168) (see paper)
    40% identity, 76% coverage of query (155 bits)

8sutA Crystal structure of yisk from bacillus subtilis in complex with reaction product 4-hydroxy-2-oxoglutaric acid
    40% identity, 76% coverage of query (155 bits)

BMULJ_04921 / A0A0H3KT28 2,4-didehydro-3-deoxy-L-fuconate hydrolase (EC 3.7.1.26) from Burkholderia multivorans (strain ATCC 17616 / 249) (see 2 papers)
    36% identity, 95% coverage of query (154 bits)

6v77B / A0QTY3 Crystal structure of a putative hpce protein from mycobacterium smegmatis
    40% identity, 70% coverage of query (152 bits)

6j5xA / Q8NLC0 Crystal structure of fumarylpyruvate hydrolase from corynebacterium glutamicum in complex with mn2+ and pyruvate (see paper)
    32% identity, 96% coverage of query (150 bits)

A0A1R4GQY2 3-fumarylpyruvate hydrolase (EC 3.7.1.20) from Corynebacterium glutamicum (see paper)
    32% identity, 96% coverage of query (150 bits)

6j5xB Crystal structure of fumarylpyruvate hydrolase from corynebacterium glutamicum in complex with mn2+ and pyruvate
    32% identity, 96% coverage of query (150 bits)

BPHYT_RS34210 2,4-diketo-3-deoxy-L-rhamnonate hydrolase (EC 3.7.1.-) from Burkholderia phytofirmans PsJN
    36% identity, 95% coverage of query (148 bits)

UGL_BURL3 / Q39BA7 Ureidoglycolate lyase; UGL; Ureidoglycolase; Ureidoglycolatase; Ureidoglycolate hydrolase; EC 4.3.2.3 from Burkholderia lata (strain ATCC 17760 / DSM 23089 / LMG 22485 / NCIMB 9086 / R18194 / 383) (see paper)
    36% identity, 95% coverage of query (146 bits)

8gsrA / Q1NEI7 Crystal structure of l-2,4-diketo-3-deoxyrhamnonate hydrolase from sphingomonas sp. (Apo-form) (see paper)
    34% identity, 95% coverage of query (141 bits)

8gstC Crystal structure of l-2,4-diketo-3-deoxyrhamnonate hydrolase from sphingomonas sp. (Pyruvate bound-form)
    34% identity, 95% coverage of query (141 bits)

lra6 / Q1NEI7 2,4-didehydro-3-deoxy-L-fuconate hydrolase (EC 3.7.1.26) from Sphingomonas sp. (strain SKA58) (see paper)
    34% identity, 95% coverage of query (139 bits)

K0A9N9 fumarylacetoacetase (EC 3.7.1.2) from Exiguobacterium antarcticum (see paper)
    35% identity, 97% coverage of query (137 bits)

6iymA / K0A9N9 Fumarylacetoacetate hydrolase (eafah) from psychrophilic exiguobacterium antarcticum (see paper)
    33% identity, 97% coverage of query (134 bits)

hbzF / Q0QFQ3 maleylpyruvate hydrolase monomer (EC 3.7.1.23) from Pseudomonas alcaligenes (see 2 papers)
HBZF_PSEAC / Q0QFQ3 Maleylpyruvate hydrolase; MPH11; EC 3.7.1.23 from Pseudomonas alcaligenes (see 3 papers)
Q0QFQ3 maleylpyruvate hydrolase (EC 3.7.1.23) from Pseudomonas alcaligenes (see 2 papers)
    31% identity, 98% coverage of query (132 bits)

Y2993_MYCTU / I6Y276 Protein Rv2993c from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
    35% identity, 72% coverage of query (124 bits)

3r6oA / B1MJ53 Crystal structure of a probable 2-hydroxyhepta-2,4-diene-1, 7- dioateisomerase from mycobacterium abscessus (see paper)
    31% identity, 81% coverage of query (120 bits)

3qdfA / B2HIH3 Crystal structure of 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase from mycobacterium marinum (see paper)
    34% identity, 72% coverage of query (114 bits)

A0A076VF18 fumarylacetoacetase (EC 3.7.1.2) from Rhodotorula diobovata (see paper)
    32% identity, 72% coverage of query (103 bits)

CPH_NEONM / A0A3G9JYJ6 Caffeoylpyruvate hydrolase; CPH; Fungal bioluminescence cycle protein cph; EC 3.7.-.- from Neonothopanus nambi (Agaricus nambi) (see 2 papers)
    33% identity, 73% coverage of query (101 bits)

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Build an alignment for BWI76_RS05690 and 23 homologs with ≥ 30% identity

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Additional hits (identity < 30%)

G2IPX5 maleylpyruvate hydrolase (EC 3.7.1.23) from Sphingobium sp. SYK-6 (see paper)
    26% identity, 95% coverage of query (100 bits)

A0A0M3SVN7 fumarylacetoacetase (EC 3.7.1.2) from Cupriavidus gilardii (see paper)
    30% identity, 81% coverage of query (98.2 bits)

4dbhA / Q8NQY2 Crystal structure of cg1458 with inhibitor (see paper)
    33% identity, 71% coverage of query (97.1 bits)

6jvwB / G2IPX5 Crystal structure of maleylpyruvate hydrolase from sphingobium sp. Syk-6 in complex with manganese (ii) ion and pyruvate (see paper)
    27% identity, 95% coverage of query (93.6 bits)

naaD / F8QQ75 3-fumarylpyruvate hydrolase (EC 3.7.1.20) from Bradyrhizobium sp. JS329 (see paper)
    27% identity, 76% coverage of query (79.7 bits)

xacE / D4GP28 2-dehydro-3-deoxy-L-arabinonate dehydratase (EC 4.2.1.43; EC 4.2.1.141) from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (see 3 papers)
KDXD_HALVD / D4GP28 Probable 2-keto-3-deoxyxylonate dehydratase; KDXD; EC 4.2.1.141 from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii) (see 2 papers)
    27% identity, 76% coverage of query (62.0 bits)

2q1dX 2-keto-3-deoxy-d-arabinonate dehydratase complexed with magnesium and 2,5-dioxopentanoate
    25% identity, 77% coverage of query (52.4 bits)

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