Searching for up to 100 curated homologs for BWI76_RS07040 FitnessBrowser__Koxy:BWI76_RS07040 (349 a.a.)
Found high-coverage hits (≥70%) to 26 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
YlbC / b0517 ureidoglycolate dehydrogenase (EC 1.1.1.350) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
allD / P77555 ureidoglycolate dehydrogenase (EC 1.1.1.350) from Escherichia coli (strain K12) (see 2 papers)
ALLD_ECOLI / P77555 Ureidoglycolate dehydrogenase (NAD(+)); EC 1.1.1.350 from Escherichia coli (strain K12) (see 2 papers)
P77555 ureidoglycolate dehydrogenase (NAD+) (EC 1.1.1.350) from Escherichia coli (see paper)
83% identity, 100% coverage of query (618 bits)
4fjuA Crystal structure of ureidoglycolate dehydrogenase in ternary complex with nadh and glyoxylate (see paper)
83% identity, 97% coverage of query (600 bits)
1vbiA / Q53W84 Crystal structure of type 2 malate/lactate dehydrogenase from thermus thermophilus hb8
36% identity, 91% coverage of query (213 bits)
MDH_METFV / P16142 Malate/(S)-sulfolactate dehydrogenase; EC 1.1.1.310; EC 1.1.1.37; EC 1.1.1.82 from Methanothermus fervidus (strain ATCC 43054 / DSM 2088 / JCM 10308 / V24 S) (see paper)
P16142 L-2-hydroxycarboxylate dehydrogenase (NAD+) (EC 1.1.1.337) from Methanothermus fervidus (see 2 papers)
35% identity, 96% coverage of query (191 bits)
comC / Q58820 L-2-hydroxycarboxylate dehydrogenase (EC 1.1.1.337) from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (see 4 papers)
COMC_METJA / Q58820 L-sulfolactate dehydrogenase; (R)-2-hydroxyacid dehydrogenase; (R)-sulfolactate dehydrogenase; L-2-hydroxycarboxylate dehydrogenase (NAD(+)); EC 1.1.1.337 from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii) (see paper)
Q58820 L-2-hydroxycarboxylate dehydrogenase (NAD+) (EC 1.1.1.337) from Methanocaldococcus jannaschii (see 3 papers)
2x06A / Q58820 Sulfolactate dehydrogenase from methanocaldococcus jannaschii (see paper)
36% identity, 95% coverage of query (190 bits)
A0A0U3EA38 L-2-hydroxycarboxylate dehydrogenase (NAD+) (EC 1.1.1.337) from Methanobrevibacter millerae (see paper)
32% identity, 95% coverage of query (177 bits)
1v9nA / O59028 Structure of malate dehydrogenase from pyrococcus horikoshii ot3
31% identity, 95% coverage of query (159 bits)
comC / Q1QWN5 R-sulfolactate oxidoreductase (EC 1.1.1.338) from Chromohalobacter salexigens (strain ATCC BAA-138 / DSM 3043 / CIP 106854 / NCIMB 13768 / 1H11) (see 2 papers)
COMC_CHRSD / Q1QWN5 (2R)-3-sulfolactate dehydrogenase (NADP(+)); (R)-2-hydroxyacid dehydrogenase; (R)-sulfolactate dehydrogenase; EC 1.1.1.338 from Chromohalobacter salexigens (strain ATCC BAA-138 / DSM 3043 / CIP 106854 / NCIMB 13768 / 1H11) (see paper)
Q1QWN5 (2R)-3-sulfolactate dehydrogenase (NADP+) (EC 1.1.1.338) from Chromohalobacter salexigens (see paper)
30% identity, 95% coverage of query (139 bits)
PY2CR_STAND / D7A0Y0 Delta(1)-pyrroline-2-carboxylate reductase; Pyr2C reductase; EC 1.5.1.49 from Starkeya novella (strain ATCC 8093 / DSM 506 / JCM 20403 / CCM 1077 / IAM 12100 / NBRC 12443 / NCIMB 10456) (see paper)
32% identity, 95% coverage of query (129 bits)
2cwfB / Q4U331 Crystal structure of delta1-piperideine-2-carboxylate reductase from pseudomonas syringae complexed with NADPH (see paper)
31% identity, 94% coverage of query (128 bits)
2cwhA Crystal structure of delta1-piperideine-2-carboxylate reductase from pseudomonas syringae complexed with NADPH and pyrrole-2-carboxylate
31% identity, 94% coverage of query (128 bits)
PY2CR_PSEUB / Q4U331 Delta(1)-pyrroline-2-carboxylate/Delta(1)-piperideine-2-carboxylate reductase; Pyr2C/Pip2C reductase; N-methyl-L-amino acid dehydrogenase; EC 1.5.1.21; EC 1.4.1.17 from Pseudomonas syringae pv. tomato (see paper)
Q4U331 1-piperideine-2-carboxylate/1-pyrroline-2-carboxylate reductase [NAD(P)H] (EC 1.5.1.1); 1-piperideine-2-carboxylate/1-pyrroline-2-carboxylate reductase (NADPH) (EC 1.5.1.21) from Pseudomonas syringae (see paper)
31% identity, 94% coverage of query (127 bits)
mdpE / A2SP37 tert-butoxymethanol dehydrogenase from Methylibium petroleiphilum (strain ATCC BAA-1232 / LMG 22953 / PM1) (see paper)
31% identity, 86% coverage of query (126 bits)
Build an alignment for BWI76_RS07040 and 13 homologs with ≥ 30% identity
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dhpC / D7PC15 1-hydroxy-2-phosphorylethylphosphonate dehydrogenase from Streptomyces luridus (see paper)
29% identity, 81% coverage of query (124 bits)
3i0pA / C4M213 Crystal structure of malate dehydrogenase from entamoeba histolytica
28% identity, 88% coverage of query (124 bits)
dpkA / Q88GX6 Δ1-piperideine-2-carboxylate reductase (EC 1.5.1.1) from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440) (see 4 papers)
31% identity, 93% coverage of query (123 bits)
PY2CR_PSEPU / Q5FB93 Delta(1)-pyrroline-2-carboxylate/Delta(1)-piperideine-2-carboxylate reductase; Pyr2C/Pip2C reductase; N-methyl-L-amino acid dehydrogenase; NMAADH; EC 1.5.1.21; EC 1.4.1.17 from Pseudomonas putida (Arthrobacter siderocapsulatus) (see 2 papers)
dpkA / BAD89743.1 delta1-piperideine-2-carboxylate reductase from Pseudomonas putida (see paper)
30% identity, 93% coverage of query (122 bits)
1z2iA / Q7CRW4 Crystal structure of agrobacterium tumefaciens malate dehydrogenase, new york structural genomics consortium
29% identity, 83% coverage of query (122 bits)
PYCR2_BURM1 / A9ALD3 Delta(1)-pyrroline-2-carboxylate reductase 2; Pyr2C reductase 2; Proline ketimine reductase 2; EC 1.5.1.49 from Burkholderia multivorans (strain ATCC 17616 / 249) (see paper)
28% identity, 95% coverage of query (117 bits)
PYCR1_BURCM / Q0B9S2 Delta(1)-pyrroline-2-carboxylate reductase 1; Pyr2C reductase 1; Proline ketimine reductase 1; EC 1.5.1.49 from Burkholderia ambifaria (strain ATCC BAA-244 / AMMD) (Burkholderia cepacia (strain AMMD)) (see paper)
29% identity, 78% coverage of query (113 bits)
HcxB / b0801 hydroxycarboxylate dehydrogenase B (EC 1.1.1.237) from Escherichia coli K-12 substr. MG1655 (see 2 papers)
hcxB / P30178 hydroxycarboxylate dehydrogenase B (EC 1.1.1.237) from Escherichia coli (strain K12) (see paper)
HCXB_ECOLI / P30178 Hydroxycarboxylate dehydrogenase B; 2-oxoglutarate reductase; Hydroxyphenylpyruvate reductase; Phenylpyruvate reductase; EC 1.1.1.-; EC 1.1.1.237 from Escherichia coli (strain K12) (see paper)
29% identity, 89% coverage of query (112 bits)
2g8yA / P30178 The structure of a putative malate/lactate dehydrogenase from e. Coli.
29% identity, 89% coverage of query (111 bits)
PY2CR_PSEAE / Q9I492 Delta(1)-pyrroline-2-carboxylate/Delta(1)-piperideine-2-carboxylate reductase; Pyr2C/Pip2C reductase; Delta(1)-pyrroline-(4S)-hydroxy-2-carboxylate reductase; Pyr4SH2C reductase; Proline ketimine reductase; EC 1.5.1.21; EC 1.5.1.- from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see 3 papers)
Q9I492 1-piperideine-2-carboxylate/1-pyrroline-2-carboxylate reductase (NADPH) (EC 1.5.1.21) from Pseudomonas aeruginosa (see paper)
27% identity, 95% coverage of query (110 bits)
PY2CR_AGRFC / Q7CVK1 Delta(1)-pyrroline-2-carboxylate reductase; Pyr2C reductase; Proline ketimine reductase; EC 1.5.1.49 from Agrobacterium fabrum (strain C58 / ATCC 33970) (Agrobacterium tumefaciens (strain C58)) (see paper)
30% identity, 77% coverage of query (102 bits)
1s20G / P37672 A novel NAD binding protein revealed by the crystal structure of e. Coli 2,3-diketogulonate reductase (yiak) northeast structural genomics consortium target er82 (see paper)
23% identity, 94% coverage of query (87.8 bits)
YiaK / b3575 2,3-diketo-L-gulonate reductase (EC 1.1.1.130) from Escherichia coli K-12 substr. MG1655 (see 5 papers)
yiaK / P37672 2,3-diketo-L-gulonate reductase (EC 1.1.1.130) from Escherichia coli (strain K12) (see 4 papers)
DLGD_ECOLI / P37672 2,3-diketo-L-gulonate reductase; 2,3-DKG reductase; 3-dehydro-L-gulonate 2-dehydrogenase; EC 1.1.1.130 from Escherichia coli (strain K12) (see 2 papers)
23% identity, 94% coverage of query (87.8 bits)
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Lawrence Berkeley National Laboratory