Searching for up to 100 curated homologs for BWI76_RS07190 FitnessBrowser__Koxy:BWI76_RS07190 (445 a.a.)
Found high-coverage hits (≥70%) to 29 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
CadB / b4132 lysine:cadaverine antiporter from Escherichia coli K-12 substr. MG1655 (see 10 papers)
CadB / P0AAE8 lysine:cadaverine antiporter from Escherichia coli (strain K12) (see 12 papers)
CADB_ECOLI / P0AAE8 Cadaverine/lysine antiporter from Escherichia coli (strain K12) (see 8 papers)
TC 2.A.3.2.2 / P0AAE8 Cadaverine:lysine antiporter [Catalyzes cadaverine uptake via H+ symport (Km=21μM) and cadaverine export (Km=300 μM) via cadaverine:lysine antiport.] (Soksawatmaekhin et al., 2004). Modeling tools have been used to gain information about the structures and functions of CadB and PotE in E. coli from Escherichia coli (see 6 papers)
91% identity, 100% coverage of query (793 bits)
cadB / AAQ16630.1 CadB, partial from Escherichia coli (see paper)
89% identity, 78% coverage of query (627 bits)
ADIC_SALTY / P60066 Arginine/agmatine antiporter from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 2 papers)
39% identity, 98% coverage of query (322 bits)
YjdD / b4115 arginine:agmatine antiporter from Escherichia coli K-12 substr. MG1655 (see 3 papers)
adiC / P60061 arginine:agmatine antiporter from Escherichia coli (strain K12) (see 2 papers)
ADIC_ECOLI / P60061 Arginine/agmatine antiporter from Escherichia coli (strain K12) (see 6 papers)
ADIC_ECO57 / P60063 Arginine/agmatine antiporter from Escherichia coli O157:H7 (see 3 papers)
TC 2.A.3.2.5 / P60061 Homodimeric electrogenic arginine (Km=80μM):agmatine antiporter, AdiC, involved in extreme acid resistance (Fang et al., 2007; Gong et al., 2003; Iyer et al., 2003). A projection structure at 6.5 Å resolution has been published (Casagrande et al., 2008), and the 3.2 Å resolution X-ray structure was determined by Fang et al., 2009 and Gao et al., 2009 from Escherichia coli (see 6 papers)
adiC / GB|AAN45533.1 arginine/agmatine antiporter from Shigella flexneri (see 6 papers)
39% identity, 98% coverage of query (318 bits)
5j4nA / P60061 Crystal structure of the l-arginine/agmatine antiporter adic in complex with agmatine at 2.6 angstroem resolution (see paper)
39% identity, 98% coverage of query (318 bits)
3l1lA Structure of arg-bound escherichia coli adic
38% identity, 98% coverage of query (300 bits)
PotE / b0692 putrescine transporter PotE from Escherichia coli K-12 substr. MG1655 (see 13 papers)
potE / P0AAF1 putrescine transporter PotE from Escherichia coli (strain K12) (see 14 papers)
POTE_ECOLI / P0AAF1 Putrescine transporter PotE; Putrescine-proton symporter / putrescine-ornithine antiporter from Escherichia coli (strain K12) (see 5 papers)
TC 2.A.3.2.1 / P0AAF1 Putrescine:ornithine antiporter for putrescine export; putrescine:H+ symporter for uptake from Escherichia coli (see 5 papers)
33% identity, 95% coverage of query (202 bits)
Build an alignment for BWI76_RS07190 and 7 homologs with ≥ 30% identity
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ARCD_PSEAE / P18275 Arginine/ornithine antiporter; Arginine-ornithine exchanger from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see 3 papers)
TC 2.A.3.2.3 / P18275 Arginine:ornithine antiporter from Pseudomonas aeruginosa (see 3 papers)
arcD / GB|AAG08555.1 arginine/ornithine antiporter from Pseudomonas aeruginosa (see 3 papers)
25% identity, 83% coverage of query (107 bits)
AAXC_CHLPN / Q9Z6M8 Arginine/agmatine antiporter from Chlamydia pneumoniae (Chlamydophila pneumoniae) (see paper)
TC 2.A.3.2.7 / Q9Z6M8 Arginine/agmatine antiporter from Chlamydia pneumoniae (see 4 papers)
27% identity, 76% coverage of query (106 bits)
YdgI / b1605 putative arginine:ornithine antiporter from Escherichia coli K-12 substr. MG1655 (see 5 papers)
ARCD_ECOLI / P0AAE5 Putative arginine/ornithine antiporter from Escherichia coli (strain K12) (see paper)
25% identity, 96% coverage of query (98.6 bits)
arcD / CAA04686.1 arginine /ornithine antiporter from Lactobacillus sakei (see 2 papers)
26% identity, 97% coverage of query (94.4 bits)
TC 2.A.3.2.11 / F2HL56 Arginine/Ornithine antiporter of 526 aas and 14 TMSs from Lactococcus lactis subsp. lactis (strain CV56)
23% identity, 90% coverage of query (90.5 bits)
ARCD1_LACLM / A2RNI5 Arginine/ornithine antiporter ArcD1; Arginine/ornithine exchanger from Lactococcus lactis subsp. cremoris (strain MG1363) (see 2 papers)
23% identity, 90% coverage of query (89.4 bits)
TC 2.A.3.2.4 / P35865 Lysine permease from Corynebacterium glutamicum (Brevibacterium flavum) (see 2 papers)
lysI / RF|YP_225261.1 L-lysine transport protein from Corynebacterium glutamicum (see paper)
24% identity, 84% coverage of query (81.3 bits)
YhfM / b3370 fructoselysine/psicoselysine transporter from Escherichia coli K-12 substr. MG1655 (see 4 papers)
frlA / P45539 fructoselysine/psicoselysine transporter from Escherichia coli (strain K12) (see 4 papers)
FRLA_ECOLI / P45539 Probable fructoselysine/psicoselysine transporter FrlA from Escherichia coli (strain K12) (see paper)
26% identity, 71% coverage of query (67.0 bits)
PS417_05405 L-alanine and D-alanine permease from Pseudomonas simiae WCS417
26% identity, 71% coverage of query (62.4 bits)
AO356_17670 L-alanine and D-alanine permease from Pseudomonas fluorescens FW300-N2C3
26% identity, 71% coverage of query (60.8 bits)
AO353_16120 D-alanine and L-alanine transporter from Pseudomonas fluorescens FW300-N2E3
26% identity, 71% coverage of query (58.2 bits)
AAT6_CAEEL / Q22397 Amino acid transporter protein 6 from Caenorhabditis elegans (see 2 papers)
TC 2.A.3.8.27 / Q22397 Amino acid transporter 6 (AAT-6). Interacts with NRFL-1, the C. elegans NHERF orthologue to promote localization to the intestinal luminal membrane from Caenorhabditis elegans
24% identity, 73% coverage of query (57.8 bits)
TC 2.A.3.12.4 / Q9LHN7 Golgi polyamine/paraquot uptake transporter of 478 aas, LAT4. Also called PUT2 and PAR1. Mutations give rise to paraquot resistance (Par1) both in A. thaliana and in rice. Probably present in the chloroplast membrane from Arabidopsis thaliana
22% identity, 73% coverage of query (57.8 bits)
SLC7A8 / Q9UHI5 large neutral amino acids transporter small subunit 2 from Homo sapiens (see 4 papers)
LAT2_HUMAN / Q9UHI5 Large neutral amino acids transporter small subunit 2; L-type amino acid transporter 2; hLAT2; Solute carrier family 7 member 8 from Homo sapiens (Human) (see 14 papers)
TC 2.A.3.8.20 / Q9UHI5 Large neutral amino acids transporter small subunit 2 (L-type amino acid transporter 2) (hLAT2) (Solute carrier family 7 member 8). Certain detergents stabilize and allow purification of the 4F2hc-LAT2 complex, allowing the measurement of substrate binding. In addition, an improved 3D map could be obtained from Homo sapiens (see 12 papers)
24% identity, 76% coverage of query (55.8 bits)
LAT2_MOUSE / Q9QXW9 Large neutral amino acids transporter small subunit 2; L-type amino acid transporter 2; mLAT2; Solute carrier family 7 member 8 from Mus musculus (Mouse) (see 6 papers)
24% identity, 76% coverage of query (55.5 bits)
LAT2_RABIT / Q9N1Q4 Large neutral amino acids transporter small subunit 2; 4F2-LC5; L-type amino acid transporter 2; Solute carrier family 7 member 8 from Oryctolagus cuniculus (Rabbit) (see paper)
25% identity, 76% coverage of query (55.1 bits)
LAT2_RAT / Q9WVR6 Large neutral amino acids transporter small subunit 2; L-type amino acid transporter 2; Solute carrier family 7 member 8 from Rattus norvegicus (Rat) (see 4 papers)
TC 2.A.3.8.6 / Q9WVR6 L-type neutral amino acid transporter, LAT2 (Na+-independent with broad specificity for all L-isomers of neutral amino acids; preferred substrate: Phe, His, Trp, Ile, Val, Leu, Gln, Cys, Ser; catalyzes obligatory exchange with μM affinities on the outside and mM affinities on the inside [1000x difference]). Both LAT2 and LAT1 (2.A.3.8.1) catalyze uptake of S-nitro-L-cysteine (Li and Whorton, 2005). Also transports thyroid hormones from Rattus norvegicus (Rat) (see 3 papers)
24% identity, 76% coverage of query (55.1 bits)
YifK / b3795 putative transporter YifK from Escherichia coli K-12 substr. MG1655 (see 5 papers)
thrP / P27837 threonine/serine:H+ symporter ThrP from Escherichia coli (strain K12) (see 5 papers)
23% identity, 71% coverage of query (54.3 bits)
GADC_ECO57 / P58229 Glutamate/gamma-aminobutyrate antiporter; Glu/GABA antiporter from Escherichia coli O157:H7 (see paper)
22% identity, 70% coverage of query (53.5 bits)
7b00A Human lat2-4f2hc complex in the apo-state
24% identity, 76% coverage of query (51.6 bits)
7cmiB The lat2-4f2hc complex in complex with leucine
24% identity, 76% coverage of query (51.6 bits)
7cmhB / Q9UHI5 The lat2-4f2hc complex in complex with tryptophan (see paper)
24% identity, 76% coverage of query (51.6 bits)
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Lawrence Berkeley National Laboratory