Searching for up to 100 curated homologs for BWI76_RS07630 FitnessBrowser__Koxy:BWI76_RS07630 (677 a.a.)
Found high-coverage hits (≥70%) to 27 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
BetT / b0314 choline:H+ symporter from Escherichia coli K-12 substr. MG1655 (see 6 papers)
BetT / P0ABC9 choline:H+ symporter from Escherichia coli (strain K12) (see 5 papers)
BETT_ECOLI / P0ABC9 High-affinity choline transport protein from Escherichia coli (strain K12) (see 2 papers)
TC 2.A.15.1.4 / P0ABC9 The high-affinity, proton- or sodium-driven, secondary symporter, BetT from Escherichia coli (see 4 papers)
94% identity, 100% coverage of query (1310 bits)
BETT2_ACIAD / Q6FDF5 Osmo-dependent choline transporter BetT2 from Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1) (see paper)
69% identity, 99% coverage of query (967 bits)
TC 2.A.15.1.3 / Q4ZLW8 Low affinity (0.9 mM), high efficiency, choline/glycine betaine:H+ symporter, BetT from Pseudomonas syringae pv. syringae (strain B728a) (see paper)
45% identity, 97% coverage of query (597 bits)
GBTR_ACIAD / Q6F754 Glycine betaine transporter from Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1) (see paper)
TC 2.A.15.1.9 / Q6F754 High affinity glycine betaine uptake system from Acinetobacter sp. (strain ADP1) (see paper)
40% identity, 98% coverage of query (519 bits)
BETS_RHIML / G3XCN6 Glycine betaine/proline betaine transporter BetS from Rhizobium meliloti (Ensifer meliloti) (Sinorhizobium meliloti) (see paper)
TC 2.A.15.1.5 / Q92WM0 Glycine-betaine/proline-betaine:Na+ symporter, BetS; BetT, OpuD (see 2 papers)
39% identity, 97% coverage of query (473 bits)
BETT1_ACIAD / Q6FDF6 Osmo-independent choline transporter BetT1 from Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1) (see paper)
40% identity, 75% coverage of query (407 bits)
tmaT / A0A0B5RUB0 trimethylamine transporter from Myroides profundi (see paper)
TMAT_MYRPR / A0A0B5RUB0 Trimethylamine transporter; TMA transporter; TMA-specific transporter from Myroides profundi (see paper)
41% identity, 73% coverage of query (387 bits)
Q0PCR9 ABC-type quaternary amine transporter (EC 7.6.2.9) from Aphanothece halophytica (see paper)
40% identity, 75% coverage of query (361 bits)
BETL_LISMN / Q9X4A5 Glycine betaine transporter BetL; Glycine betaine-Na(+) symporter from Listeria monocytogenes (see 4 papers)
TC 2.A.15.1.11 / Q9X4A5 Glycine betaine transporter BetL (Glycine betaine-Na(+) symporter) from Listeria monocytogenes (see 4 papers)
39% identity, 72% coverage of query (360 bits)
GBT_DESHY / Q24SP9 Probable glycine betaine transporter from Desulfitobacterium hafniense (strain Y51) (see paper)
37% identity, 73% coverage of query (338 bits)
ECTP_CORGL / Q79VE0 Ectoine/glycine betaine/proline transporter EctP from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) (see 3 papers)
TC 2.A.15.1.2 / Q79VE0 Ectosine/glycine betaine/proline:Na+ symporter (see 2 papers)
ectP / CAA04760.1 EctP protein from Corynebacterium glutamicum (see paper)
32% identity, 88% coverage of query (323 bits)
BCCT1_VIBPA / Q87PP5 Glycine betaine/proline/choline/ectoine transporter VP1456 from Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633) (see paper)
36% identity, 73% coverage of query (318 bits)
BCCT2_VIBPA / Q87NZ5 Glycine betaine/proline/choline transporter VP1723 from Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633) (see paper)
34% identity, 74% coverage of query (318 bits)
BCCT3_VIBPA / Q87NG3 Glycine betaine transporter 1 from Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633) (see paper)
35% identity, 73% coverage of query (310 bits)
ECTT_VIRPA / Q93AK1 Ectoine/hydroxyectoine transporter from Virgibacillus pantothenticus (see paper)
TC 2.A.15.1.8 / Q93AK1 The ectoine/hydroxyectoine:Na+ symporter, EctT from Virgibacillus pantothenticus
35% identity, 74% coverage of query (309 bits)
LCOP_CORGL / Q8NN75 Betaine/ectoine transporter LcoP; Low capacity osmoregulated permease from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) (see 3 papers)
TC 2.A.15.1.7 / Q8NN75 The ectoine/glycine:Na+ symporter, LcoP from Corynebacterium glutamicum (see paper)
36% identity, 73% coverage of query (298 bits)
BETP_CORGL / P54582 Glycine betaine transporter BetP; Glycine betaine permease from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) (see 17 papers)
TC 2.A.15.1.10 / P54582 Glycine betaine transporter, BetP. The x-ray structure is known (3PO3; 2WIT; Ressl et al., 2009). Regulatory crosstalk in the trimeric BetP has been reported (Gärtner et al., 2011). An extracellular K+ -dependent interaction site modulates betaine-binding (Ge et al., 2011). The porter is trimeric and exhibits structural asymmetry (Tsai et al., 2011). The C-terminal domain is involved in osmosensing and is trimeric like wild-type BetP from Corynebacterium glutamicum (see paper)
35% identity, 75% coverage of query (296 bits)
4llhA / P54582 Substrate bound outward-open state of the symporter betp (see paper)
36% identity, 70% coverage of query (292 bits)
3p03C Crystal structure of betp-g153d with choline bound
36% identity, 70% coverage of query (291 bits)
BCCT4_VIBPA / Q87J97 Glycine betaine transporter 2 from Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633) (see paper)
31% identity, 71% coverage of query (209 bits)
Build an alignment for BWI76_RS07630 and 20 homologs with ≥ 30% identity
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CAIT_PROMH / B4EY22 L-carnitine/gamma-butyrobetaine antiporter from Proteus mirabilis (strain HI4320) (see 2 papers)
TC 2.A.15.2.2 / B4EY22 The L-carnitine:γ-butyrobetaine antiporter, CaiT from Proteus mirabilis (strain HI4320) (see 2 papers)
27% identity, 74% coverage of query (166 bits)
2wswA / B4EY22 Crystal structure of carnitine transporter from proteus mirabilis (see paper)
27% identity, 73% coverage of query (165 bits)
4m8jA Crystal structure of cait r262e bound to gamma-butyrobetaine
27% identity, 73% coverage of query (162 bits)
YaaP / b0040 L-carnitine:γ-butyrobetaine antiporter from Escherichia coli K-12 substr. MG1655 (see paper)
caiT / P31553 L-carnitine:γ-butyrobetaine antiporter from Escherichia coli (strain K12) (see 4 papers)
CAIT_ECOLI / P31553 L-carnitine/gamma-butyrobetaine antiporter from Escherichia coli (strain K12) (see 7 papers)
TC 2.A.15.2.1 / P31553 Carnitine:γ-butyrobetaine antiporter from Escherichia coli (see 7 papers)
27% identity, 73% coverage of query (154 bits)
2wsxA / P31553 Crystal structure of carnitine transporter from escherichia coli (see paper)
26% identity, 72% coverage of query (150 bits)
3hfxA Crystal structure of carnitine transporter
27% identity, 72% coverage of query (148 bits)
gbuE / A0A415DZ18 γ-butyrobetaine transporter from Emergencia timonensis (see paper)
24% identity, 75% coverage of query (132 bits)
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Lawrence Berkeley National Laboratory